Clinical trials: Mediation
Anemia, Cardiac Surgery
Mediation Analysis in Cardiac Surgery
This study investigates the mediating role of intraoperative allogeneic red blood cell transfusion in the relationship between preoperative anaemia and postoperative complications in patients undergoing cardiac surgery.
- Conditions
- Anemia, Cardiac Surgery, Transfusion, Mediation
- Trial name
- MACS (NCT07092683)
- Testing
- anemia, nonanemia
- Where
- China
- Volunteers
- 13,683 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Depression, Stress
Internet Based Psychological Support
The investigators have developed interactive, multimedia-intensive, computer-based treatment programs that include depression (Problem-Solving Therapy), stress management, and conflict management.
- Conditions
- Depression, Stress, Conflict Resolution
- Trial name
- NCT02726061
- Testing
- Internet-based psychological support
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Equine-assisted Therapy, Addiction
The Impact of Equine-Assisted Therapy on Mental Health and Addictive Behaviors in Patients Receiving Addiction Treatment
Addiction is a major public health issue. According to the World Health Organization (2024), approximately 400 million people worldwide suffer from alcohol- or drug-related disorders, resulting in nearly 3.2 million deaths per…
- Conditions
- Equine-assisted Therapy, Addiction, Recidivism, Addictive Behaviors
- Trial name
- EQUI-ADDICT (NCT07495839)
- Testing
- Equine mediation
- Volunteers
- 22 people
- Sponsor
- Hopital La Musse
Depression, Anxiety
Investigating a Mediation Model of Emotion Regulation and Psychological Resilience in Relationship Between Mindfulness and Negative Emotions Among College Students in Guangzhou
This study examines whether a four-week mindfulness-based intervention can reduce depression, anxiety, and stress among college students in Guangzhou, China.
- Conditions
- Depression, Anxiety, Stress
- Trial name
- NCT07741422
- Testing
- Mindfulness-Based Intervention, Health Education
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Universiti Sains Malaysia
Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolically Healthy Obesity
Metabolically Healthy Obesity Increases the Risks of MASLD and Hyperuricemia
Although metabolically healthy obesity (MHO) is often considered a relatively benign obesity, its association with the risk of metabolic dysfunction-associated steatotic liver disease (MASLD) and hyperuricemia remains unclear.
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolically Healthy Obesity, Hyperuricemia
- Trial name
- NCT07001865
- Where
- China
- Volunteers
- 17,040 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Exercise, Cognition
Sympathetic Nervous System Mediation of Acute Exercise Effects on Childhood Brain and Cognition
Today's children have become increasingly inactive and unfit, with >50% of children not meeting the recommended 60 min of moderate-to-vigorous physical activity.
- Trial name
- NCT03592238
- Testing
- Aerobic Exercise Intervention, Trier Social Stress Test for Children, Seated Rest
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Prematurity, Framing
Framing and Decision Making in Neonatology
The purpose of this study is to study how people make decisions regarding delivery room management for infants born extremely premature when survival and long term outcomes are uncertain.
- Conditions
- Prematurity, Framing, Perinatal Decision Making
- Trial name
- NCT01421238
- Testing
- Survey
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Columbia University
Nicotine Dependence, Cigarettes
Negotiating a Quit Date or Not in Online Interventions
The primary purpose of the current study is to test the effect of providing users of automated web-based smoking cessation interventions with the option of negotiating and re-negotiating the quit date.
- Trial name
- NCT03194919
- Testing
- Endre: a digital smoking cessation counsellor
- Where
- 2 sites in Czechia, Norway
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Total Knee Replacement, Mediation
Mindfulness Meditation Intervention Study
The goal of this pilot study is to develop a randomized control trial study with sufficient power to definitely address if a preop mindfulness meditation intervention can improve post-total knee arthroplasty mental well-being or…
- Conditions
- Total Knee Replacement, Mediation, Feasibility
- Trial name
- NCT06180486
- Testing
- Mindfulness Meditation Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
Family Functioning
Family Mediation Program For At-Risk Youth
The goal of this project is to conduct a pilot evaluation of a parent-child mediation program for at-risk youth. It is investigating whether families who receive parent-child mediation show greater improvement in family…
- Trial name
- NCT01944748
- Testing
- Families Able To Resolve Situations (FARS)
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- RAND
Human Immunodeficiency Virus Infection (HIV), Sexually Transmitted Disease (STD)
Being Responsible for Ourselves HIV Risk Reduction for Black MSM
The incidence of HIV/AIDS among African American men who have sex with men (MSM) is alarming, and the public health response to this urgent situation has been hampered by a lack of sexual risk reduction interventions with solid…
- Trial name
- BRO (NCT02561286)
- Testing
- BRO HIV Risk Reduction Intervention, Health Promotion Intervention
- Where
- United States
- Volunteers
- 595 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Substance Use Disorders, Substance Abuse
tDCS and Impulsivity
Substance use disorder (SUD) affects more than 23 million Americans and claims more than 70,000 lives annually. With 40-60% relapse rate, SUD patients are high hospital utilizers, 65% of the incarcerated population, and are at…
- Conditions
- Substance Use Disorders, Substance Abuse, Substance Use
- Trial name
- NCT05845164
- Testing
- tDCS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arizona
Frail Elderly Syndrome
Exercise Mediation on Hormonal, Immune and Psychological Well-being in Institutionalized Frail Older Women.
Frailty syndrome is a complex aging expression determined by ontogenetic and phylogenetic factors. Chronic stress has been shown to have immunosuppressive effects, to accelerate immunosenescence and to cause cumulative disorders…
- Trial name
- UC (NCT04435899)
- Testing
- Physical exercise
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Epilepsy
Impact of Canine Mediation Practice in Psychomotor Therapy on Improving the Quality of Life in Adult Epileptic Patients.
In addition to the search for new pharmaceutical or surgical solutions that could improve the therapeutic management of epileptic individuals, it is interesting to ask whether other complementary approaches, such as canine…
- Trial name
- MCP-Epi (NCT06898749)
- Testing
- canine mediation, standard psychomotor therapy
- Where
- 2 sites in France
- Volunteers
- 76 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Pregnancy Related, Mediation
Investigation of the Effect of Mindfulness-Based Stress Reduction Program on in Pregnant Women
This study was planned to examine the effects of the Mindfulness-Based Stress Reduction Program, which is one of the popular concepts of the 21st century, on depression, psychological well-being and prenatal attachment, which are…
- Conditions
- Pregnancy Related, Mediation, Depression, Maternal-Fetal Relations
- Trial name
- NCT05804838
- Testing
- Mindfulness stress reduction program group
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Developmental Language Disorder
Training Inner Speech in Children With Developmental Language Disorder
The complex and unclear relationship between language and executive function (EF) creates barriers to developing effective interventions for children with developmental language disorder (DLD) whose language difficulties often…
- Trial name
- NCT06880731
- Testing
- Modeling with Verbal Mediation, Modeling Only
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Patellofemoral Pain Syndrome
The Effect of Muscle Strengthening Associated With Neuromuscular Stimulus in Patients With Patellofemoral Pain During Negotiating Stairs
Assess pain, function, hip and knee strength and kinematics of trunk and lower limbs during ascent and descent stairs after the addition of neuromuscular training to hip muscle strengthening.
- Trial name
- NCT02591680
- Testing
- Neuromuscular training, Muscle strengthening, Sensorimotor
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Nove de Julho
Chronic Low Back Pain (CLBP)
A Mediation Analysis Investigating Dry Needling Treatment Mechanisms in a Chronic Low Back Pain Population
Low back pain is a common problem that many adults experience at some point in their lives. One treatment being studied is dry needling, a technique where a small needle is inserted into a specific area of muscle to help relieve…
- Trial name
- NCT06940492
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Schizophrenia
Cognitive Factors Mediating the Relationship Between Childhood Trauma and Auditory Hallucinations in Schizophrenia
BACKGROUND It is demonstrated that strong associations between trauma suffered in childhood and having schizophrenia, and more specifically to experience acoustic-verbal hallucinations (AVH).
- Trial name
- HADITRYOS (NCT04481217)
- Testing
- Self-questionnaires battery, Socio-demographic screening
- Where
- 2 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Grenoble
Violence, Gender-Based, Violence, Domestic
Responsible Engaged and Loving (REAL) Fathers Intervention Evaluation
The goal of this stepped-wedge cluster randomized control trial is to assess whether a Ugandan community-based intervention for young fathers (ages 18-25 years) of children ages 0-3 years impacts fathers' knowledge, attitudes…
- Conditions
- Violence, Gender-Based, Violence, Domestic, Violence, Sexual, Violence, Physical
- Trial name
- NCT06100679
- Testing
- Responsible Engaged and Loving (REAL) Fathers Initiative
- Where
- 4 sites in Uganda
- Volunteers
- 4,728 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego