Clinical trials: Mediation
Chronic Obstructive Pulmonary Disease
Mindfulness Mediation Intervention in Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to assess the feasibility and potential impact of an eight week program of meditation on expiratory time, anxiety and dyspnea in people with COPD.
- Trial name
- NCT01577329
- Testing
- Mindfulness meditation
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Michigan
Mental Disease
Mental Health Reinforcement in Wayapi and Teko Communities in French Guiana : Evaluation of the Impact of a Mediation Based Activity in Municipalities of Camopi and Trois Saut in French Guiana
In French Guiana, Indigenous people experience high levels of psychological distress and higher rates of suicidal behavior than the rest of the population.
- Trial name
- MCS Impact (NCT07808801)
- Where
- French Guiana
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Behavioral Flexibility, Healthy Volunteers
Flexibility, Alcohol Misuse, and Excitation
The goal of this study is to learn whether a single non-invasive brain stimulation alpha-transcranial alternating current stimulation (alpha-tACS) session changes measures of excitability in the prefrontal cortex.
- Conditions
- Behavioral Flexibility, Healthy Volunteers, High Risk Alcohol Use
- Trial name
- FLAME (NCT06634771)
- Testing
- 10 Hz transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Family Caregiver and Patient Mutual Negotiation of Roles and Responsibilities
Family Caregiving Role Adjustment and Dyadic Mutuality
Background: Cancer causes changes in the lives of patients and in the lives of their caregivers. Patients and caregivers feel stress and they affect each other as they deal with these changes.
- Trial name
- NCT02566174
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Alcohol Use, Unspecified
Risk Factors for Stress-induced Alcohol Misuse: Genetic Predictors and Mediation by Personality Type
To examine whether variation in 'risk-taking' personality and linked genetic variants predicts susceptibility to, and resilience against, stress-induced alcohol misuse.
- Trial name
- RISK (NCT04533802)
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Chronic Nonspecific Neck Pain
Comparative Effectiveness Randomised Controlled Trial of Hybrid Muscle Conditioning
Chronic nonspecific neck pain is a prevalent and recurrent condition frequently characterised by persistent impairments in cervical-scapular neuromuscular function.
- Trial name
- NCT07837414
- Testing
- Hybrid exercise group, Motor control exercise group, Endurance exercise group
- Where
- Hong Kong
- Volunteers
- 210 people
- Sponsor
- The Hong Kong Polytechnic University
Normal Non-fluency
Effect of Short Term Atypical Antipsychotic Administration Compared to Placebo on Hepatic Insulin Extraction
Within the past 20 years, there has been a striking increase in the incidence of obesity 1;2, type 2 diabetes mellitus (T2DM) 3-5, and cardiovascular diseases (CVD) in the schizophrenic population 6-8 .
- Trial name
- NCT02447835
- Testing
- Olanzapine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michael Rickels
Colorectal Cancer
Study of the Therapeutic Use of Language in Patients With Metastatic Colorectal Cancer
The purpose of this study is to determine if the degree of agreement between patients and their physicians regarding the "story" of the illness correlates with improved patient symptom control and quality of life.
- Trial name
- NCT00711672
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Hematology and Oncology Associates of NE Pennsylvania
Major Depressive Disorder
Deficits in Emotion Regulation Skills as a Maintaining Factor in Major Depressive Disorder
The primary aim of the study is to evaluate the efficacy of a systematic training of general affect regulation skills (ART) on the reduction of depressive symptom in individuals meeting criteria for major depressive disorder…
- Trial name
- NCT01330485
- Testing
- Affect Regulation Training, Common Factor Control Condition
- Where
- 3 sites in Germany
- Volunteers
- 218 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 5
Improving Medication Safety for Kidney Disease With a Digital Drug Dosing Tool in Nova Scotia Community Pharmacy Practice.
Chronic kidney disease (CKD) is a common condition. It occurs in approximately 7 out of 100 Canadians and is highest in rural settings. The kidneys are responsible for the removal of many drugs from the body.
- Trial name
- NCT06820372
- Testing
- Electronic Drug Dosing and Decision Support Kidney (eDoseCKD) Tool
- Volunteers
- 125 people
- Sponsor
- Nova Scotia Health Authority
Drug Interaction
The Interaction of Herbs and Statins
This project includes two separate pharmacokinetic studies with simvastatin and rosuvastatin, respectively. Each study is an open-label, single-dose, randomized, three-phase (no herbs, with green tea, with soy isoflavones)…
- Trial name
- NCT05072405
- Testing
- Simvastatin 20 mg (Zocor®, MSD), rosuvastatin 10 mg (Crestor®, Astra Zeneca)
- Where
- Hong Kong
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Alzheimer Disease, Cognitive Impairment
Negotiation Training for Caregiver Communication in AD
The purpose of this study is to design a Negotiation and Dispute Resolution (NDR) training intervention to improve communication and address resolution of conflicts that family caregivers of patients with cognitive impairment…
- Trial name
- NCT04837937
- Testing
- Caregiver vs. Patient [Beginner], Caregiver vs. Caregiver, Caregiver vs. Physician
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Northwestern University
ADD/ADHD
Ultra-processed Food Consumption and Behavioral Disorder and Cognitive Function
The goal of this interventional study is to determine whether reducing ultra-processed food consumption in children and adolescents can improve cognitive function.
- Trial name
- UPF (NCT07465081)
- Testing
- Nutritional education group
- Where
- Taiwan
- Volunteers
- 154 people
- Sponsor
- China Medical University Hospital
Moderate to Severe Dementia
Pilot Study of a Robot-assisted Intervention for the Management of Care-induced Pain in Dementia
Health care professionals lack tools to deal with acute pain in patients with moderate to severe dementia during daily nursing situations.
- Trial name
- PARODOL (NCT03591822)
- Testing
- A : Systemic evaluation of the pain and mediation with the PARO therapeutic robot, B : Systemic evaluation of the pain
- Where
- 5 sites in France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Failure Preserved Ejection Fraction, Pregnancy Complications
Middle-aged Women With Adverse Pregnancy Outcomes and Heart Failure With Preserved Ejection Fraction
Due to the steady increase in the burden of HFpEF, especially in women, it is an important task to search for new markers and early predictors associated with the development of this disease.
- Trial name
- MAPO-HF (NCT06338943)
- Testing
- Echocardiography, Questionnaire
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
A Brief Negotiation Interview Chatbot to Improve Buprenorphine Engagement Among Justice-Involved Individuals
Primary Objective: Conduct pilot study to assess effects of brief negotiation interview (BNI) Chatbot among individuals involved in the Connecticut criminal justice system with opioid use disorder (OUD).
- Conditions
- Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe, Criminal Behavior
- Trial name
- BNICHAT (NCT04982627)
- Testing
- BNI Chatbot, OUD Education & Treatment Resources
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Center for Progressive Recovery, LLC
Pancreas Neoplasm
Postoperative Outcomes After Partial Duodenopancreatectomy Versus Total Pancreatectomy
The goal of this observational study is to compare short-term outcomes after partial pancreatoduodenectomy and total pancreatectomy in adults undergoing elective surgery for pancreatic or periampullary neoplasms in Switzerland.
- Trial name
- NCT07831694
- Volunteers
- 3,602 people
- Sponsor
- Cantonal Hospital of St. Gallen
Diabetes Complications, Depression Anxiety Disorder
Joint Effects of Physical Activity and Diet Quality on Depression and Mortality in Diabetes
This observational study aims to investigate whether physical activity (PA) and diet quality (DQ) can reduce depression and mortality risk in individuals with diabetes.
- Conditions
- Diabetes Complications, Depression Anxiety Disorder, Diabetes
- Trial name
- NCT07122271
- Where
- China
- Volunteers
- 3,621 people
- Sponsor
- Minghui Wang
Depression, Anxiety
The Effect of Hatha Yoga on Mental Health
The goal of this clinical trial is to determine the effects of a 10-week (2x a week; 45-minute per session) Hatha yoga intervention in adults ages 18-25 (n = 45) on mental health outcomes.
- Conditions
- Depression, Anxiety, Mental Health Issue
- Trial name
- NCT05777044
- Testing
- Yoga
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Auburn University
Traumatic Brain Injury (TBI) Patients, Equine-assisted Therapy
Impact of a Standardized Equine Mediation Program on the Evolution of the Psycho-behavioral Profile of Adults With Traumatic Brain Injuries Experiencing Impaired Quality of Life (EPONA).
In France, 155,000 traumatic brain injuries (TBIs) are treated annually, representing a major public health challenge. The sequelae vary depending on the lesions and include a range of motor disorders as well as complex cognitive…
- Conditions
- Traumatic Brain Injury (TBI) Patients, Equine-assisted Therapy, Cognitive Disorders, Quality of Life
- Trial name
- EPONA (NCT06713538)
- Testing
- Equine assisted therapy, Physical activity
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hopital La Musse