Clinical trials: Medical Cannabis
Osteoarthritis of Knee, Osteoarthritis Hip
Cannabinoids for Osteoarthritis Pain Effectiveness Trial
This study aims to investigate whether oral cannabis extracts can effectively manage pain caused by osteoarthritis (OA), a common joint condition affecting one in seven Canadians.
- Trial name
- COPE (NCT06878417)
- Testing
- CBD, THC
- Where
- 3 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Fibromyalgia
Medical Cannabis for Treating Pain Related to Fibromyalgia
The goal of this interventional study is to learn about the effect of Medicinal Cannabis (Bedrocan®) on Fibromyalgia patients with pain resistant to conventional therapy.
- Trial name
- Bedrocan®-LD (NCT05939466)
- Testing
- Bedrocan®-type cannabis (22% THC, <1% CBD)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Universita degli Studi della Basilicata
Autism Spectrum Disorder
Safety and Efficacy of Oral Full-Spectrum Medicinal Cannabis Plant Extract in Children With Autism Spectrum Disorder.
This is a 20-week open-label study to evaluate the safety and efficacy of full-spectrum medicinal cannabis plant extract < 0.08% THC (FEN164) in children with Autism Spectrum Disorder.
- Trial name
- NCT05516407
- Testing
- FEN164
- Where
- Australia
- Volunteers
- 18 people
- Sponsor
- Fenix Innovation Group
Palliative Care
Pilot Study of MC in Paediatric Palliative Care
The goal of this pilot study is to explore the feasibility and acceptability of a medicinal cannabis clinical trial into easing the symptoms of children undergoing palliative care for non-oncological conditions.
- Trial name
- NCT05615389
- Testing
- Medicinal Cannabis - C12T12, Medicinal Cannabis - C20T5
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Murdoch Childrens Research Institute
Safety Study for Future Treatment of Psoriasis
A Phase I, Double Blind, Randomized, Placebo Controlled, Maximal Dose Study to Determine the Safety, Tolerability of Topical Cream Containing MGC (Medical Grade Cannabis) in Healthy Volunteers
This single center, prospective, double-blind, placebo-controlled, randomized two parts study (part I and part II) will assess the safety of topical cream (3% CBD and 3% THC), applied twice daily (bid), in healthy subjects, for…
- Trial name
- NCT02976779
- Testing
- OWC MGC cream, OWC Control Cream
- Where
- Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- One World Cannabis Ltd.
Multiple Sclerosis
Short-Term Effects of Medicinal Cannabis Therapy on Spasticity in Multiple Sclerosis
The purpose of this study is to determine whether or not smoked marijuana improves spasticity in patients with multiple sclerosis.
- Trial name
- NCT00248378
- Testing
- Smoked Cannabis
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Center for Medicinal Cannabis Research
Neuropathic Pain
Medicinal Cannabis for Painful HIV Neuropathy
The purpose of this study is to determine if medicinal cannabis (marijuana) is safe and effective for treating pain in individuals with HIV-associated distal, sensory-predominant polyneuropathy (DSPN).
- Trial name
- NCT00255580
- Testing
- Smoked cannabis
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Center for Medicinal Cannabis Research
Cancer, Epilepsy
Real World Evidence on the Use of Medical Cannabis in Pediatrics
CAN-RWE is an observational study that is following 500 children who have authorizations for medical cannabis for two years from across Canada.
- Conditions
- Cancer, Epilepsy, Neurodevelopmental Disorders
- Trial name
- CAN-RWE (NCT05863910)
- Testing
- Medical Cannabis
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Manitoba
Multiple Sclerosis
The Effects of Different Medical Marijuana Strains on Motor and Cognitive Function in People With Multiple Sclerosis
Over the last two years, the United States has witnessed enormous change concerning the acceptance of marijuana. The number of persons with MS (PwMS) using cannabis to treat their symptoms is expected to rise, and it is important…
- Trial name
- NCT03172741
- Testing
- Medical Marijuana
- Sponsor
- Colorado State University
Long COVID
Feasibility of Cannabidiol for the Treatment of Long COVID
This is an open label, phase 2 clinical trial to assess the feasibility of a cannabidiol (CBD) dominant medicinal cannabis for the treatment of Long COVID.
- Trial name
- NCT04997395
- Testing
- MediCabilis Cannabis sativa 50
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Bod Australia
HIV Positive, Marijuana Smoking
Medical Marijuana Use in HIV+ Patients Prospective Cohort Study
The investigators are interested in understanding personal factors such as medical conditions and mental health, as well as social and economic factors, that influence marijuana (and other substance) use in HIV-positive patients.
- Trial name
- MMC-1 (NCT01536899)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Wayne State University
Dementia with Behavioral Disturbance
MEDical CANnabis for Improving Symptoms During Severe DEMentia Disorders in Long-term Care Facility in Geneva
The behavioral and psychological symptoms of dementia affect up to 80% of long-term facilities residents with severe dementia. They seriously alter the quality of life of patients, relatives, and health professionals.
- Trial name
- MedCanDem (NCT05432206)
- Testing
- Cannabis Sativa Oil
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- Fondation pour l'accueil et l'hébérement des personnes âgées
Healthy Subjects
Comparison of Safety, Tolerability and Pharmacokinetics of Medical Grade Cannabis (MGC) Orally Disintegrating Tablets With Buccal Sativex®, in Healthy Adult Volunteers
This is a preliminary study designed to assess the safety and properties of a new oral formulation containing the two most common cannabinoids used for medicinal purposes - Tetrahydrocannabinol (THC) and Cannabidiol (CBD).
- Trial name
- NCT03936907
- Testing
- OWCP Orally Disintegrating Tablet, Sativex
- Where
- Israel
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- One World Cannabis Ltd.
HIV Positive
Medical Marijuana Use in HIV+ Patients: Probability Survey
More scientific information is needed about medical marijuana use among HIV positive patients. There is conflicting information about the use of marijuana, use of medical marijuana, and the associations between them and health…
- Trial name
- MMS (NCT01536912)
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- Wayne State University
Tourette Syndrome, Cannabis
The Effect of Medical Cannabis on Tics, Premonitory Urge and Psychiatric Comorbidity in Adults With Tourette Syndrome
Medical cannabis (MC) is a standard treatment in Israel to adults with resistant Gilles de la Tourette syndrome (GTS). While small randomized control trials assessed THC efficacy on tics and premonitory urge, only small…
- Trial name
- NCT05115318
- Testing
- Medical Cannabis
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Chemotherapy-induced Peripheral Neuropathy
The Kinetics of Endocannabinoids in Patients With Chemotherapy Induced Peripheral Neuropathy by Using Medical Cannabis.
Chemotherapy-induced peripheral neuropathy (CIPN) is the most common neurological cancer treatment complication. Medical cannabis is indicated in Israel for the treatment of chronic pain, spasticity and for the control of pain…
- Trial name
- NCT04376437
- Testing
- medical cannabis
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- HaEmek Medical Center, Israel
Autism Spectrum Disorder
The Effects of Medical Cannabis in Children With Autistic Spectrum Disorder
Children with autism spectrum disorder (ASD) commonly exhibit comorbid symptoms such as aggression, hyperactivity and anxiety. Data on the effects of cannabidiol rich cannabis extract use for ASD is promising but still limited.
- Trial name
- NCT05212493
- Testing
- Cannabis oil
- Where
- Israel
- Volunteers
- 128 people
- Sponsor
- Assaf-Harofeh Medical Center
Pancreatic Cancer Non-resectable, Pancreatic Cancer Metastatic
Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer
Many patients with advanced pancreatic cancer and colorectal cancer experience burdensome and difficult-to-treat symptoms. The impact of multiple symptoms (called "symptom burden") can negatively affect a patient's quality of…
- Conditions
- Pancreatic Cancer Non-resectable, Pancreatic Cancer Metastatic, Colorectal Cancer Metastatic
- Trial name
- CanPan-C (NCT06605430)
- Testing
- Medical Cannabis
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- HealthPartners Institute
Chronic Pain
Reactions of Older Adults Driving After Cannabis Exposure
Objective of the Protocol: The primary aim of the current protocol is to examine whether or not habitual use of medical marijuana affects psychomotor functioning operationalized as driving performance.
- Trial name
- ROADACE (NCT04629716)
- Testing
- Medical Cannabis
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Florida State University
Cancer, Cancer (With or Without Metastasis)
Assessing Claims of Cannabis as an Anti-cancer Agent (CATA)
The purpose of the study is to find out how cannabis may help control cancer growth by reviewing medical records of patients who report cannabis helped treat their cancer.
- Trial name
- CATA (NCT07107607)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute