Clinical trials: Medical Disorders
Type 2 Diabetes
Culturally Tailored Nutrition Therapy to Improve Dietary Adherence of Type 2 Diabetes Patients in Benin, Africa
The clinical trial aims to assess the effectiveness of the Objectif Santé Diabète Benin (OSanDiaBé), a culturally tailored medical nutrition therapy (MNT), in enhancing diabetes management and nutrition choices.
- Trial name
- OSanDiaBé (NCT07145684)
- Testing
- A culturally tailored medical nutrition therapy
- Where
- Benin
- Volunteers
- 64 people
- Sponsor
- University of Arizona
Chronic Obstructive Pulmonary Disease (13645005)
Advancing the Patient Experience in Chronic Obstructive Pulmonary Disease (APEX COPD)
APEX COPD is registry to provide a mechanism to standardize, store and utilize data to enable greater power to answer key research questions, and to improve patient outcomes in COPD primary care.
- Trial name
- APEX COPD (NCT04285047)
- Testing
- Advancing Patient Experience (APEX) in COPD
- Where
- 4 sites in United States
- Volunteers
- 4,500 people
- Sponsor
- Optimum Patient Care
Diagnoses Disease
Inverting Grayscale Improves Detection of Proximal Femur Fracture
Proximal femur fractures (PFF) are a worldwide public health concern. A delay in the diagnosis and treatment worsens the prognosis.
- Trial name
- NCT05318378
- Testing
- BIXAM
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre de l'arthrose, Paris
Premature Infant
Calmer Brains in Very Preterm Infants
Very preterm infants in the neonatal intensive care unit (NICU) need lifesaving medical procedures which can be stressful and affect brain development.
- Trial name
- NCT07262385
- Testing
- Calmer
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Pulmonary Disease, Chronic Obstructive
Spiriva Observational Study Measuring Saint George's Respiratory Questionnaire (SGRQ) in Routine Medical Practice in Central & Eastern European Region
The objective of this observational study is to collect and evaluate data on Health Related Quality of Life (HRQoL) of Spiriva delivered by HandiHaler, using disease specific SGRQ in the national samples of Central \& Central…
- Trial name
- NCT01006135
- Where
- 864 sites in Croatia, Poland and 4 more
- Volunteers
- 4,852 people
- Sponsor
- Boehringer Ingelheim
Crohn's Disease, IBD
Impact of Medical Treatment on Sexual Function in Patients With Crohn's Disease
Crohn's disease is a chronic inflammatory condition of the intestines that causes abdominal pain, diarrhea, tunnels around the anus (fistulas), and extraintestinal symptoms.
- Trial name
- NCT02619552
- Testing
- Anti-TNF, Steroids
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Maryland, Baltimore
Heart Failure, Atrial Fibrillation
Rhythm Control - Catheter Ablation With or Without Anti-arrhythmic Drug Control of Maintaining Sinus Rhythm Versus Rate Control With Medical Therapy and/or Atrio-ventricular Junction Ablation and Pacemaker Treatment for Atrial Fibrillation
Atrial fibrillation and heart failure are two common heart conditions that are associated with an increase in death and suffering. When both of these two conditions occur in a patient the patient's prognosis is poor.
- Trial name
- RAFT-AF (NCT01420393)
- Testing
- Rhythm control, Rate Control
- Where
- 21 sites in Brazil, Canada and 2 more
- Volunteers
- 411 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Chronic Disabling, COVID-19
COVID-19 Outbreak Consequences for Outpatients Followed in PRM
Objectives This survey aims at reporting the immediate impact of the COVID-19 epidemic on outpatients followed in Physical and Rehabilitation Medicine (PRM).
- Trial name
- Handicall (NCT04384406)
- Where
- France
- Volunteers
- 467 people
- Sponsor
- University Hospital, Montpellier
Hypertension
VISN Collaborative for Improving Hypertension Management With ATHENA-HTN
This project is a VA HSR\&D-funded Quality Enhancement Research Initiative (QUERI) project to translate into practice evidence about clinical management of primary hypertension.
- Trial name
- HTN (NCT00374452)
- Testing
- ATHENA-CDS-HTN plus Guideline Link, Guideline Link Only
- Where
- 7 sites in United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chronic Myeloid Leukemia
A Study of Asciminib Safety and Efficacy in Young Adults With Chronic Myeloid Leukemia in the Gulf Region
The aim of this study is to evaluate the real-world effectiveness and safety of asciminib among young adults with chronic myeloid leukemia (CML) across the Gulf region.
- Trial name
- ASC4Young (NCT07681258)
- Volunteers
- 80 people
- Sponsor
- Novartis Pharmaceuticals
Anxiety, Loneliness
Loneliness and Health Outcomes in the High Need Population
The high need population are patients who have three or more chronic diseases and have a functional limitation in their ability to take care for themselves.
- Conditions
- Anxiety, Loneliness, Depression, Alcohol Use Disorder
- Trial name
- NCT05484258
- Testing
- Shared Medical Visit
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Sustainability, Female Infertility
Greening the Humanitas Fertility Center: How to Build a More Sustainable Medical Daily Routine
The goal of this observational study is to redefine an everyday clinical routine at the Humanitas Fertility center calculating the effects derived from the reduction of inappropriate and avoidable tests, procedures, tools and…
- Trial name
- Green (NCT06239051)
- Where
- Italy
- Volunteers
- 136 people
- Sponsor
- Istituto Clinico Humanitas
Fetal Hydrops
Precision Medical Research of Non-immune Fetal Hydrops (NIFH)-From Prenatal Diagnosis to Intrauterine Treatment
Based on multi-center clinical research resources, a large-scale prospective cohort study will be conduted to make a more accurate diagnosis and intervention plan of Non-immune fetal hydrops (NIFH), and then establish NIFH…
- Trial name
- NCT02956564
- Testing
- intrauterine intervention
- Volunteers
- 144 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Aphthous Stomatitis
Hyaluronic Acid in Counteracting Aphthous Stomatitis
Oral mucosal ulcers can determine a real worsening of the quality of life. Conventional therapy usually lasts not less than 2-3 weeks, and carries a high risk of serious side effects; furthermore, ulcers often recur.
- Trial name
- NCT04884464
- Testing
- Hyaluronic acid-based gel, Chlorhexidine Gluconate
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- University of Urbino "Carlo Bo"
Surgery, Cholecystectomy, Laparoscopic
Benefits of 'Repeat Back' Protocols Within A Computer-Based Informed Consent Program
This is a VA Merit Review Study involving 7 VA medical centers participating in a parallel group randomized trial comparing "repeat back" versus standard electronic consent for 4 common elective surgical procedures (total hip…
- Conditions
- Surgery, Cholecystectomy, Laparoscopic, Prostatectomy, Arthroplasty, Replacement, Hip
- Trial name
- NCT00288899
- Testing
- Enhanced surgical iMedConsent process (with "repeat back"), standard surgical iMedConsent process
- Where
- 7 sites in United States
- Volunteers
- 575 people
- Sponsor
- VA Office of Research and Development
Genetic Disorder, Fertility Disorders
Retrospective Study on Clinical Results of Preimplantation Genetic Screening at Different Embryo Stage
Preimplantational genetic screen (PGS) is tool for diagnosis of embryo chromosome abnormality before transfer. Under this tool, patients with a family history of genetic disease or special genetic disease could avoid to produce…
- Conditions
- Genetic Disorder, Fertility Disorders, Reproductive Disorder
- Trial name
- NCT03065114
- Testing
- PGS
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yeh
Cerebral Aneurysm
A Medical Device to Treat Brain Aneurysms
An aneurysm is a bulge in a blood vessel caused by a weakness in the blood vessel wall, usually where it branches. As blood passes through the weakened blood vessel, the blood pressure causes a small area to bulge outwards like a…
- Trial name
- NCT04963933
- Testing
- Nautilus endovascular device
- Where
- 2 sites in Bulgaria, Latvia
- Volunteers
- 30 people
- Sponsor
- EndoStream Medical
Burns, Pain
VR for Pain & Sleep in Burn Patients: A RCT
This study aims to evaluate whether virtual reality (VR) can reduce pain and improve sleep quality during wound dressing changes in burn patients with 25-60% total body surface area (TBSA) burns, compared to standard care.
- Conditions
- Burns, Pain, Sleep Disturbances
- Trial name
- NCT07306442
- Testing
- Virtual Reality Distraction, Standard Care
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Abadan University of Medical Sciences
Dyspnea
Palliative Oxygen for the Relief of Breathlessness
The main goal of this study is to establish the effectiveness of palliative oxygen in the context within which it is usually provided--relief of the sensation of breathlessness and improvement in quality of life for people with…
- Trial name
- NCT00327873
- Testing
- Oxygen, Medical Air
- Where
- 7 sites in United States, Australia and 1 more
- Volunteers
- 240 people
- Sponsor
- National Health and Medical Research Council, Australia
Peripheral Vascular Disease
Radiofrequency for the Treatment of Peripheral Vascular Occlusive Disease of the Lower Extremities
The purpose of this study is to evaluate the safety and efficacy of the Minnow Medical GRST Peripheral Catheter System in the treatment of new lesions in the superficial femoral artery or the popliteal artery.
- Trial name
- NCT00751283
- Testing
- GRST Peripheral Catheter System
- Sponsor
- Vessix Vascular, Inc