Clinical trials: Medical Emergencies
Cardiovascular Diseases, Diabetes Mellitus
A Community Paramedicine Initiative for Older Adults Living in Subsidized Housing (CHAP-EMS/CP@Clinic)
Older adults living in subsidized housing report poorer health. Their age and low income make it harder for them to use community services.
- Trial name
- CHAP-EMS (NCT02152891)
- Testing
- CHAP-EMS/CP@clinic
- Where
- 5 sites in Canada
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- McMaster University
Out-of-hospital Cardiac Arrest (OHCA), Emergency Medical Services
Telemedicine-Assisted vs Conventional Telephone Instruction in Cardiopulmonary Resuscitation
Out-of-hospital cardiac arrest (OHCA) is a life-threatening emergency where early cardiopulmonary resuscitation (CPR) by bystanders can significantly improve survival.
- Trial name
- TACTIC (NCT07546474)
- Testing
- Telemedicine-Assisted CPR (TA-CPR), Dispatcher-Assisted CPR (DA-CPR)
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Siriraj Hospital
Elderly
Risk Factors for Falls After Intervention of the Urgent Medical Assistance Service (SAMU) in the Elderly Person at Home
In this project, the investigators are interested in a particular population, that of elderly subjects who used the SAMU after a fall and who are not hospitalized or are hospitalized less than 24 hours.
- Trial name
- RISING-DOM (NCT04132544)
- Testing
- standardized gerontological evaluation (EGS), Proposal for a personalized intervention plan (PIP), Follow-up
- Where
- 12 sites in France
- Volunteers
- 952 people
- Sponsor
- University Hospital, Toulouse
Drowning, Drowning, Near
Developing an Utstein-style Danish Drowning Registry: Nationwide Fatal and Nonfatal Drowning Data Since 2016
This nationwide, registry-based study aims to link Danish Prehospital Drowning Data data with inhospital data to develop a Utstein-style Danish Drowning Registry.
- Conditions
- Drowning, Drowning, Near, Drowning; Asphyxia, Drowning and Nonfatal Submersion
- Trial name
- DROWN_INHOS (NCT06334276)
- Testing
- Drowning
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Prehospital Center, Region Zealand
Education, Medical
Study of Virtual Simulated Resuscitation in Junior Clinicians
The investigators seek to examine the impact of virtual patient simulation on junior clinicians' resuscitation skills in an academic emergency department.
- Trial name
- NCT05201950
- Testing
- Virtual simulation, Team based in situ simulation
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Sepsis, Severe Sepsis
Prehospital Antibiotics Against Sepsis Trial
Sepsis is one of the most frequent reasons for referral to emergency departments (EDs) worldwide. The incidence of sepsis is likely to rise in the upcoming years.
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- PHANTASi (NCT01988428)
- Testing
- Ceftriaxone 2000 mg
- Where
- 34 sites in Netherlands
- Volunteers
- 2,672 people
- Sponsor
- Amsterdam UMC, location VUmc
Stress, Pupillometry
Stress Evaluation and Management Using High Fidelity Simulation in Medical Education
The goal of this interventional study is to collect clinical and neurophysiological information to determine whether high-fidelity simulation can serve as a stress-inducing stimulus in a population of healthy residents (Emergency…
- Conditions
- Stress, Pupillometry, High Fidelity Simulation Training, Resident Education
- Trial name
- STRATAGEM (NCT06916949)
- Testing
- Electrocardiogram, Pupillometry, Electroencephalogram
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Indication for Analgesia, Emergency Medical Service
Telemedically Supported Analgesia in the Emergency Medical Service
The aim of the study is to evaluate the safety and efficacy of telemedically supported and delegated pain therapy in the Emergency Medical Service (EMS).
- Conditions
- Indication for Analgesia, Emergency Medical Service, Teleconsultation
- Trial name
- NCT01644032
- Testing
- Teleconsultation
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- RWTH Aachen University
Decompensated Heart Failure
Vericiguat in Decompensated Cardiac Failure: Clinical Insights on Addition to Guidelines Derived Medical Therapy-VERCIG Trial
This study will compare the outcomes of Vericuguat and placebo in patient with decompensated heart failure . This study will carry out after approval from IERB.
- Trial name
- NCT07444398
- Testing
- Vericiguat tablet, Sacubitril / Valsartan
- Where
- Pakistan
- Volunteers
- 130 people
- Sponsor
- Khawaja Danish Ali
ECG
An Evaluation Study of Nursing Assistants' Performance of Electrocardiograms in Emergency Departments as Part of a Delegation of Medical Procedures
ECG is a simple diagnosis tool which provide a lot of diagnosis and therapeutic decisions. The last few years, the admission number in french emergency department increases in parallel with the ECG acquisition request.
- Trial name
- ECGSU1 (NCT07773636)
- Testing
- electrocardiogram by nursing assistant, electrocardiogram
- Volunteers
- 2,450 people
- Sponsor
- University Hospital, Angers
Sudden Cardiac Arrest, Out-of-hospital Cardiac Arrest (OHCA)
FEMART-1 Pilot Study
The FEMART-1 Pilot Study is focused on evaluating the feasibility, safety, and procedural timing of prehospital femoral arterial sheath placement in patients with non-traumatic out-of-hospital cardiac arrest (OHCA), both during…
- Conditions
- Sudden Cardiac Arrest, Out-of-hospital Cardiac Arrest (OHCA), Cardiogenic Shock Acute
- Trial name
- FEMART-1 (NCT07596446)
- Testing
- Prehospital Ultrasound-Guided Femoral Arterial Sheath Placement
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Emergency Medical Service, Prague
Acute Agitation
Medical Monitoring for Agitated Patients Pilot RCT - Medical Monitoring
The Psychiatric Emergency Services (PES) is an under researched area of clinical practice, largely in the management of acutely agitated and violent patients.
- Trial name
- NCT02512705
- Testing
- Pinel Restraints, Seclusion Room
- Volunteers
- 90 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Out-Of-Hospital Cardiac Arrest
OHCA Sports in Denmark
While regular exercise is known to prevent cardiovascular disorders, exercise might also trigger acute cardiac events such as cardiac arrest.
- Trial name
- NCT05045729
- Volunteers
- 21,298 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Pregnancy Related Complications
PRONTO: Obstetric and Neonatal Emergency Training Program: A Cluster-Randomized Trial to Measure Impact
Rates and causes of maternal mortality in Mexico have dropped only slightly; thus, reaching the internationally established Millennium Development Milestones (MDM) is still a distant goal.
- Trial name
- PRONTO (NCT01477554)
- Testing
- PRONTO training
- Volunteers
- 24 people
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Dyspnea, Heart Failure
The Triple A Initiative Study ("Aktionsbündnis Akute Atemnot")
Acute dyspnea is a common chief complaint of patients presenting to the emergency department. Patients with acute dyspnea display a high mortality rate.
- Trial name
- NCT02049853
- Testing
- NTproBNP measurement with point of care device "Cobash232" in the POCT group
- Where
- 6 sites in Germany
- Volunteers
- 67 people
- Sponsor
- Prof. Dr. Michael Christ
Primary Healthcare, Out-of-hours Medical Care
The (Cost-)Effectiveness of Physician Assistants Working at the Primary Out of Hours Emergency Service
The aim of this study is to explore the effect of substituting General Practitioners (GPs) by Physician Assistants (PAs) in out-of-hours primary care.
- Trial name
- NCT02417181
- Testing
- Care provided by Physician Assistants
- Where
- Netherlands
- Volunteers
- 10,161 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Prehospital Emergency Medical Services, Prehospital Emergency Care
The Pre-POCT-Non-Conveyance Trial: Prehospital Point-of-Care Testing to Support Non-Conveyance Decisions
The goal of this clinical trial is to evaluate whether rapid blood tests performed in the ambulance can be implemented in routine prehospital assessment of adults who are initially considered for transport to hospital.
- Conditions
- Prehospital Emergency Medical Services, Prehospital Emergency Care, Point of Care Testing
- Trial name
- NCT07503470
- Testing
- Point-of-care testing (POCT)
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Central Denmark Region
Wounds and Injuries, Trauma
Study of Team Leadership Training Effect on Patient Care
Brief Summary: Trauma is a major public health burden; it is the fifth most common cause of mortality overall in the US and accounts for the majority of deaths in patients younger than 45.
- Trial name
- NCT03155490
- Testing
- Leadership training
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Washington
Occupational Exposure, Occupational Problems
Relationship Between Health Risk and Occupational Exposure of ED
This study established a sub-cohort of emergency medical workers, for the development of health care and disease prevention solution, by identifying epidemiological characteristics and factors related to occupational exposure.
- Conditions
- Occupational Exposure, Occupational Problems, Occupational Burnout, Medical Emergencies
- Trial name
- NCT05651477
- Testing
- Wearable Device (Smart Watch), Edge-Box
- Where
- South Korea
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Chest Pain, Acute Coronary Syndrome
Digital Decision Support in the Management of Patients With Chest Pain
The goal of this observational study is to develop a decision support system in patients presenting with chest pain in the prehospital setting.
- Conditions
- Chest Pain, Acute Coronary Syndrome, Chest--Diseases
- Trial name
- BRIAN2 (NCT05767619)
- Testing
- Troponin hs-cTnI, Plasma glucose
- Where
- 3 sites in Sweden
- Volunteers
- 2,000 people
- Sponsor
- Vastra Gotaland Region