Clinical trials: Medication Non-adherence
Medication Non-adherence
Improving Adherence and Outcomes by Artificial Intelligence-Adapted Text Messages
Uncontrolled hypertension is a major cause of morbidity and mortality and many patients fail to take their antihypertensive medication as prescribed.
- Trial name
- AIM@BP (NCT02454660)
- Testing
- SMS (Text messages)
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Patient Satisfaction, Extracorporeal Shock Wave Lithotripsy
COMPARİSON OF THE EFFECTS OF ULTRASOUND-GUİDED ERECTOR SPİNAE PLANE BLOCK AND INTRAMUSCULAR NONSTEROİDAL ANTİ-INFLAMMATORY DRUG ADMİNİSTRATİON ON INTRAOPERATİVE ANALGESİA AND PATİENT SATİSFACTİON DURİNG EXTRACORPOREAL SHOCK WAVE LİTHOTRİPSY
The aim of this study is to compare two ways of reducing pain during extracorporeal shock wave lithotripsy (ESWL), a non-invasive treatment that breaks up kidney and urinary stones with shock waves.
- Conditions
- Patient Satisfaction, Extracorporeal Shock Wave Lithotripsy, Erector Spinae Plane Block
- Trial name
- NCT07880535
- Testing
- Ultrasound-guided erector spinae plane block, Diclofenac Sodium (DCS)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Hypertension, Uncontrolled Hypertension
Addressing Medication Non-adherence in Patients With Poorly Controlled Hypertension Using Urine Mass Spectrometry
Hypertension is the single largest contributor to cardiovascular disease and death. While adequate control of hypertension reduces risk of disease, many patients have uncontrolled hypertension.
- Conditions
- Hypertension, Uncontrolled Hypertension, Non-Adherence, Medication
- Trial name
- ADURINE (NCT06938633)
- Testing
- mass spectrometry analysis
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- Changi General Hospital
Chronic Inflammatory Disease
Chronic Inflammatory Rheumatism: Management of Comorbidities in Ambulatory Medicine
Identification of factors limiting compliance with the recommendations established during the evaluation of the SCORIC population by the rheumatology department of the CHU Grenoble Alpes
- Trial name
- SCORIC-A (NCT05613712)
- Testing
- Patients, Referring physician
- Where
- France
- Volunteers
- 229 people
- Sponsor
- University Hospital, Grenoble
Medication Non Adherence, Polypharmacy
Tailored Medication Management Intervention
Successful medication management is an essential instrumental activity of daily living (IADL) for older adults with polypharmacy; however, between 40%-70% of older adults fail to take their medications as prescribed.
- Trial name
- NCT04717297
- Testing
- Medication Management Remote Intervention, Waitlist Control, Medication Management In-Person Intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Washington University School of Medicine
Arterial Hypertension, Medication Nonadherence
Feasibility of a Program on a Nurse-led Telephone 6-month-follow-up for Uncontrolled Hypertensive Women
This study evaluate the feasibility of a 6-month personalized support program for hypertensive and non-observant women, led by nurses by telephone follow-up.
- Trial name
- PreDynamiques (NCT03963934)
- Testing
- Program on a nurse-led telephone 6-month-follow-up for uncontrolled hypertensive women: a patient-tailored intervention
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Mme Edith DAUCHY
Gastrointestinal Hemorrhage, Ulcer
Gastroprotective Agent Compliance in Patients at Risk Suffering From a Gastrointestinal(GI) Ulcer
The purpose of this study is to assess gastroprotective agent compliance in patients at risk suffering from a gastrointestinal bleeding ulcer or a symptomatic ulcer with NSAID.
- Trial name
- NCT01215058
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
Metastatic Renal Cancer, Stage III Renal Cell Cancer
Safety and Compliance of Renal Cancer Patients Treated by Non-IV Drugs
Generally, in the trials, an observant patient is described as correctly taking 90 to 100% of the prescribed doses. Here, the 80% compliance rate will be the cut-off between observant and non-observant patients.
- Trial name
- TOPTACOS (NCT03630692)
- Testing
- observance of oral drug treatment
- Where
- 14 sites in France
- Volunteers
- 158 people
- Sponsor
- Institut Cancerologie de l'Ouest
Schizophrenia, Schizo Affective Disorder
Financial Incentives to Improve Acceptance of Antipsychotic Injections
There is a lack of incentive approach for patients who suffer from schizophrenia yet lack the insight to accept treatment. Most existing approaches involve coercion and involuntary hospitalizations.
- Conditions
- Schizophrenia, Schizo Affective Disorder, Bipolar I Disorder
- Trial name
- NCT03192631
- Testing
- Financial incentive
- Volunteers
- 20 people
- Sponsor
- Focus Community Mental Health Team
Medication Adherence
Establishing Novel Antiretroviral Imaging for Hair to Elucidate Non-Adherence (ENLIGHTEN)
This is a pilot study to assess the feasibility, acceptability and appropriateness of delivery of the investigational "MedViewer" intervention in adult patients living with HIV who have been prescribed antiretroviral (ARV)…
- Trial name
- ENLIGHTEN (NCT04232540)
- Testing
- MedViewer report
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of North Carolina, Chapel Hill
Medication Nonadherence, Hypertension, Resistant to Conventional Therapy
The Use of Educational Technology in Improving Adherence Therapy
Few studies show the benefits of educational technologies a support for the control of chronic diseases. The approach known as 'embracement' adopts relational strategies or soft technologies which promote bonding and may impact…
- Trial name
- NCT03324386
- Testing
- Experimental: Individual Orientation, Experimental: VLE for Distance Learning, Experimental: E-blended Lerarning
- Volunteers
- 57 people
- Sponsor
- University of Sao Paulo General Hospital
Bipolar Disorder, Schizophrenia
Event Marker Ingested To Trigger Event Recorder 3.0 Psychiatry Study
Feasibility study of using a digital health feedback system (DHFS) to monitor medication-taking and physiologic and behavioral parameters in patients with bipolar disorder or schizophrenia.
- Trial name
- EMITTER3PSY (NCT01804257)
- Testing
- Digital Health Feedback System
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Proteus Digital Health, Inc.
Chronic Disease, Cardiovascular Disease
Synchronization to Improve Non-Adherence to Cardiovascular Medications
The aim of this study is to evaluate if synchronizing when patients with diabetes and/or coronary artery disease fill their prescriptions improves long-term adherence to these medications.
- Conditions
- Chronic Disease, Cardiovascular Disease, Diabetes Mellitus
- Trial name
- SyNCMed (NCT01963156)
- Testing
- Prescription synchronization
- Where
- United States
- Volunteers
- 3,675 people
- Sponsor
- Brigham and Women's Hospital
Hyperlipidemia, Medication Nonadherence
AdLip: Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medication
Investigators hypothesize that the use of a human coach-supported digital/AI personal health assistant (app) will improve adherence to cholesterol-lowering medications (statins with or without ezetimibe) among patients with…
- Trial name
- AdLip (NCT06614049)
- Testing
- Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medications
- Where
- 2 sites in Singapore
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Opiate Addiction, Medication Non-adherence
Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy
This study uses an artificial intelligence platform to automatically confirm medication ingestion. The Health Insurance Portability and Accountability Act (HIPAA)-compliant platform can be downloaded as an 'app' onto any…
- Conditions
- Opiate Addiction, Medication Non-adherence, Addiction, Opioid Dependence
- Trial name
- NCT02243670
- Testing
- AiCure monitoring and intervention
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- AiCure
Schizophrenia
Patient-Centered Medication Adherence Intervention for Schizophrenia
Efficacious antipsychotic medication treatments for schizophrenia are available; however , antipsychotic regimens frequently do not achieve their potential because of poor medication adherence.
- Trial name
- AMAIS (NCT00144027)
- Testing
- Antipsychotic medication adherence intervention
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- US Department of Veterans Affairs
Hypertension
Evidence Synthesis: Hypertension Medication Adherence & Intensification
Hypertension affects nearly 50 million Americans [1] and is the most common chronic condition among veterans. Unfortunately, many patients with established hypertension have poorly controlled blood pressure (BP); control rates in…
- Trial name
- NCT00682968
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Epilepsy, Seizure
AI-Based Mobile Intervention on Medication Non-Adherence and Transition
This study aims to examine whether the AI-personalized version of the Medilepsy® app is more effective than the non-AI (standard version without AI personalization) can improve key outcomes, such as medical adherence and…
- Trial name
- NCT07445074
- Testing
- Medilepsy® Chatbot AI-Enhanced, Medilepsy® Chatbot Standard
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Central Florida
Relapsing Multiple Sclerosis (RMS)
Non-interventional Study to Assess Adherence to Treatment for Patients With RMS (MAIN-MS)
This is an open label, non randomized, uncontrolled, multicenter, single arm observational study. In this study, the enrolled subjects will be treated with Rebif human serum albumin (HSA)-free formulation (with or without…
- Trial name
- NCT02921035
- Testing
- Rebif (Interferon beta-1a)
- Where
- 41 sites in Algeria, Argentina and 11 more
- Volunteers
- 594 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Overweight, Childhood, Obesity Prevention
High Five! - School-based Prevention of Overweight and Obesity Among 6 to 9 Year Olds
The goal of this interventional study is to assess the effectiveness of the school-based "High Five!" program in reducing overweight, obesity and high blood pressure in children aged 7-9 years old.
- Conditions
- Overweight, Childhood, Obesity Prevention, Blood Pressure
- Trial name
- DINO-PL (NCT07357857)
- Testing
- High Five
- Where
- Poland
- Volunteers
- 659 people, healthy volunteers welcome
- Sponsor
- Institute of Mother and Child, Warsaw, Poland