Clinical trials: Medicine, Emergency
Emergency Department Visit
Automatic Detection of Eligible Patients to RAUC Protocol (RAUCISABLE)
The augmented rehabilitation of emergency surgeries (ARES, RAUC in French) is a research program supported by Amiens-Picardy University Hospital and the University of Picardy Jules Verne.
- Trial name
- RAUCISABLE (NCT07037719)
- Where
- France
- Volunteers
- 300,000 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Toothache
Percocet vs. Bupivicaine for Toothaches in the ED
The goal of this study is to compare the speed and adequacy of pain relief in Emergency Department patients with a toothache after an oral analgesic or a local anesthetic administered as a nerve block or by local infiltration.
- Trial name
- NCT02862691
- Testing
- Acetaminophen/Oxycodone (Oral analgesic), Bupivicaine (Injectable local anesthetic)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Stony Brook University
Accidental Injuries, Global Child Health
The P-KIDs CARE Health Systems Intervention in Tanzania
The objective of the proposed research is to develop and pilot a locally-relevant, multicomponent intervention to streamline the triage process (e.g.
- Conditions
- Accidental Injuries, Global Child Health, Pediatric Emergency Medicine, Public Health System Research
- Trial name
- P-KIDs CARE (NCT06075108)
- Testing
- P-KIDs CARE
- Where
- Tanzania
- Volunteers
- 284 people
- Sponsor
- University of Utah
Uncomplicated Cutaneous Abscess
A Randomized Blinded Trial of Abscess Management With Packing vs No Packing
Adult patients presenting to the emergency department with superficial cutaneous abscesses will be randomized after incision and drainage to standard care with wound packing or no packing to determine if there is a difference in…
- Trial name
- NCT01698996
- Testing
- Packing vs No Packing
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Opioid Use Disorder
Contingency Management to Improve Medication for Opioid Use Disorder Continuation After the Emergency Department
Project Summary The goal of this pilot clinical trial is to assess contingency management (CM) for increasing attendance at outpatient clinics after Medication for Opioid Use Disorder (MOUD) prescription and clinic referral…
- Trial name
- CM+ED+MOUD (NCT07129902)
- Testing
- Contingency Management, Usual care as prescribed by the ED physicians
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Vermont
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm
Patient Perceptions of the Relational Empathy of Healthcare Practitioners From the Department of Emergency Medicine During the COVID-19 Pandemic
This study investigates patients' perceptions of their doctor's or nurse's empathy during an in-person interaction with the doctor or nurse wearing personal protective equipment (PPE) compared to during a video interaction with…
- Conditions
- COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05102656
- Testing
- Best Practice, Discussion, Questionnaire Administration
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- M.D. Anderson Cancer Center
Emergency Medicine
Development and Evaluation of a Patient Safety Model
Despite systems for early detection of critical illness, 12% of patients in the emergency department develop clinical deterioration with an increased risk of death as a result.
- Trial name
- NCT03457272
- Testing
- New risk assessment
- Where
- 4 sites in Denmark
- Volunteers
- 34,556 people
- Sponsor
- University of Aarhus
Nosocomial Infections
ED Residents MBP During CVC Placement: Sim Lab Based Training
1. Baseline performance in maximal barrier precaution technique of Emergency Medicine (EM) residents, certified in CVC placement, is poor 2.
- Trial name
- EM CVC MBP (NCT00791583)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Opioid-use Disorder, Opioid Dependence
Young Houston Emergency Opioid Engagement System
The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a community-based research program integrating assertive outreach, medication for opioid use disorder (MOUD), behavioral…
- Conditions
- Opioid-use Disorder, Opioid Dependence, Opioid Overdose, Opioid Use
- Trial name
- YHEROES (NCT04811014)
- Testing
- Buprenorphine, Naloxone Drug Combination, Individual Counseling, Peer Recovery Support Services
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- The University of Texas Health Science Center, Houston
Migraine, Hemicrania
Home Detox in Medication Overuse Headache (MOH) During Covid-19 Emergency
Medication Overuse Headache (MOH) is a disabling condition that affects the 2% of migraine population. Medication overuse (MO) makes this condition very difficult to treat.
- Trial name
- MOHC (NCT04410536)
- Testing
- Symptomatic drugs, Bridge therapy, Mindfulness program
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Seasonal Mood Disorder
Vitamin D Supplementation and Effects on Mood in Emergency Medicine Residents
Seasonal mood changes, and even feelings of depression, appear to have an association with decreased amounts of vitamin D in people living in geographic areas where exposure to sunlight during the winter months is relatively low.
- Trial name
- NCT03739671
- Testing
- Vitamin D, No Vitamin D
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Corewell Health South
Cardiac Arrest, Out-Of-Hospital, Cardiac Arrest Due to Underlying Cardiac Condition
AID-OMIE - Artificial Intelligence in Detection of Occlusive Myocardial Infarction in Emergency Medicine
Study Objective and Hypothesis The study hypothesizes that artificial intelligence (AI)-assisted interpretation of the 12-lead electrocardiogram (ECG) can improve the care of patients resuscitated after out-of-hospital cardiac…
- Trial name
- AID-OMIE (NCT06767709)
- Volunteers
- 200 people
- Sponsor
- Institute of Mountain Emergency Medicine
Symptomatic Irreversible Pulpitis, Postoperative Endodontic Pain Following Emergency Root Canal Treatment
Tobradex as Intracanal Medicament
The goal of this prospective clinical study was to evaluate and compare the short-term effects of two intracanal medicaments-calcium hydroxide and a tobramycin-dexamethasone combination (Tobradex)-on postoperative pain following…
- Trial name
- NCT07332936
- Testing
- Calcium Hydroxide (Ca(OH)2), Tobramycin + Dexamethasone
- Where
- Saudi Arabia
- Volunteers
- 43 people
- Sponsor
- Umm Al-Qura University
Emergency Medicine
International Big Data Centre in Emergency Medicine
This observational study aims to use electronic health records to build an International Big Data Centre in Emergency Medicine, within the Institute of Sciences in Emergency Medicine (ISEM) at the Guangdong Provincial People's…
- Trial name
- NCT05616416
- Where
- China
- Volunteers
- 500,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Emergencies
Microcirculation in Prehospital Medicine
Diagnostic and risk stratification are limited in emergencies. The measurement of microcirculation might identify patients with poor perfusion but compensated macrocirculation such as in beginning shock.
- Trial name
- MicroCircPreHo (NCT04265066)
- Testing
- microcirculation
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Development, Human, Well-Being
The Impact of Professional Coaching on Early Career Academic Emergency Physicians
This research study is designed to answer the question: How does professional coaching impact early career academic emergency medicine physician goal attainment, leadership strengths, well-being, and burnout?
- Conditions
- Development, Human, Well-Being, Professional Burnout, Goals
- Trial name
- NCT03125330
- Testing
- Professional coaching
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pediatric Emergency Medicine, Therapeutic Turnaround Time
Effectiveness of a Mobile App in Reducing Therapeutic TAT in an Emergency Department
This study is a single center, non-equivalent comparison group, pre-post study in a tertiary pediatric emergency department in Switzerland.
- Trial name
- NCT05557331
- Testing
- PIMPmyHospital (mobile app)
- Where
- 2 sites in Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Hip Fractures
Regional Anesthesia by PENG-Block in Emergency Department
The study is a single-centre, open-label randomized comparative trial. Adult patients admitted to the emergency department for a hip fracture will be enrolled.
- Trial name
- ED-PENGBLOCK (NCT05673486)
- Testing
- PENG Block, Multimodal analgesia
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Migraine
A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache
Rimegepant (Nurtec) is an orally administered small molecule CGRP receptor antagonist with efficacy in the acute treatment of migraine.
- Trial name
- NCT06473597
- Testing
- Rimegepant, Rizatriptan Benzoate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Antonios Likourezos
Acute Pain Due to Trauma, Analgesia
Fentanyl OR Esketamine for Traumatic PAIN (FORE-PAIN) Trial
Fentanyl and esketamine are both standard of care for treatment of acute severe traumatic pain in the prehospital setting in the Netherlands. However, it is not known whether they are equally effective and safe.
- Conditions
- Acute Pain Due to Trauma, Analgesia, Fentanyl, Esketamine
- Trial name
- FORE-PAIN (NCT06051227)
- Testing
- Fentanyl Citrate, Esketamine
- Where
- Netherlands
- Volunteers
- 235 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)