Clinical trials: Medicine, Emergency
Primary Care Quality Metrics, Well Child Visits in First 15 Months of Life NQF 1392
The Impact of Patient Complexity on Healthcare Utilization
Healthcare providers are routinely being assessed for metrics designed to assess the quality of the care they deliver. There is growing consensus that these measurements, which typically assess the percentage of patients meeting…
- Conditions
- Primary Care Quality Metrics, Well Child Visits in First 15 Months of Life NQF 1392, Diabetes Mellitus NQF 0059, Colorectal Cancer Screening NQF 0034
- Trial name
- NCT03327896
- Testing
- Charlson score and Community Social Deprivation
- Volunteers
- 200,000 people
- Sponsor
- OCHIN, Inc.
Ventilation Therapy, PEEP, Occult
PEEP vs. ZEEP in Out-of-Hospital-Cardiac-Arrest
Out-of-hospital cardiac arrest (OHCA) remains a major cause of mortality, with low survival probabilities to hospital discharge.
- Conditions
- Ventilation Therapy, PEEP, Occult, CPR, Cardiac Arrest (CA)
- Trial name
- PerAVent (NCT06836830)
- Testing
- PEEP 5 mbar, ZEEP 0 mbar
- Where
- 3 sites in Germany
- Volunteers
- 600 people
- Sponsor
- Muehlenkreiskliniken, MKK
Intracranial Hemorrhages, Acute Ischemic Stroke
AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Intracranial Hemorrhages, Acute Ischemic Stroke, Hydrocephalus, Cerebral Infarction
- Trial name
- AI-REACT (NCT06018545)
- Testing
- Ground truthing, Reading
- Where
- 4 sites in United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Mass Casualty Incidents
Impact of Ten Second Triage vs. Sieve on Triage Performance in Simulated Mass-Casualty Incidents
This study will compare two emergency triage algorithm - Ten Second Triage (TST) versus Sieve - to see which one works better during simulated mass-casualty incidents.
- Trial name
- NCT07436052
- Testing
- Ten Second Triage algorithm, Sieve triage algorithm
- Where
- Switzerland
- Volunteers
- 201 people
- Sponsor
- Stuby Loric
Asthma
A Computerized Asthma Management System in the Pediatric Emergency Department
The primary goal of this study is that the combination of a computerized asthma reminder system with implementation of an guideline will increase utilization and adherence of guideline-driven care, leading to improved patient…
- Trial name
- NCT01070147
- Testing
- Computerized Asthma Management System
- Where
- United States
- Volunteers
- 1,631 people
- Sponsor
- Vanderbilt University Medical Center
Emergency Medicine, Frontline Providers
N95 Reuse During COVID-19
During critical personal protective equipment (PPE) shortages, such as those associated with the COVID-19 pandemic, Centers for Disease Control (CDC) recommends N95 extended use (wearing the same N95 for multiple patient…
- Conditions
- Emergency Medicine, Frontline Providers, Healthcare Worker
- Trial name
- ReuseN95 (NCT05148793)
- Where
- United States
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Acute Pain
Topical Piroxicam vs Soulagel in the Treatment of Acute Extremity Pain After Emergency Department Discharge
Acute soft tissues injuries are a common complaint for emergency department (ED) visit. RICE and Topical non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used to reduce pain and inflammation.
- Trial name
- TPS (NCT05054023)
- Testing
- Soulagel®, Arthrosyl®
- Where
- Tunisia
- Volunteers
- 1,525 people
- Sponsor
- University of Monastir
Drug Overdose
Pharmacodynamics and Arteriovenous Differences of Naloxone in Healthy Participants Exposed to an Opioid
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least in Norway. To save lives, immediate treatment with a μ-opioid antidote such as naloxone is required.
- Trial name
- OPI-15-001 (NCT02405988)
- Testing
- Intravenous naloxone, Remifentanil
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Drug Overdose, Opioid Withdrawal
Feasibility of the Utilization of Buprenorphine in the Emergency Room to Treat Clinical Opioid Withdrawal
The investigators are trying to determine whether they can effectively treat patients suffering from acute opioid withdrawal in the Emergency Department at Virginia Commonwealth University Health System (VCUHS) and subsequently…
- Conditions
- Drug Overdose, Opioid Withdrawal, Opioid-use Disorder
- Trial name
- NCT03489161
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Virginia Commonwealth University
Suicidal and Self-injurious Behavior
An ED-based RCT of Lethal Means Counseling for Parents of At-Risk Youth
The National Action Alliance to Prevent Suicide recently released a research agenda aimed at significantly reducing suicide over the next decade.
- Trial name
- NCT03143283
- Testing
- Safety Study Lethal Means Counseling
- Where
- 8 sites in United States
- Volunteers
- 575 people
- Sponsor
- Northeastern University
Pneumonia, Fungal Pneumonia
Derivation and Validation of the Fungal Pneumonia Assessment and Likelihood Predictor Score
The FUNGAL-P study is a single-center observational study designed to derive and validate a clinical prediction score for the early identification of fungal pneumonia in adult patients presenting with pneumonia.
- Conditions
- Pneumonia, Fungal Pneumonia, Aspergillosis Pneumonia, Pulmonary Aspergillosis
- Trial name
- FUNGAL-P (NCT07681583)
- Testing
- FUNGAL-P Score Assessment
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Myocardial Infarction, Angina, Unstable
Novel Method to Diagnose Acute Myocardial Ischemia
The aim of this study is to improve the detection of heart attack in people who come to a hospital emergency room (ER) with cardiac symptoms.
- Conditions
- Myocardial Infarction, Angina, Unstable, Myocardial Ischemia, Coronary Disease
- Trial name
- NCT00285922
- Where
- United States
- Volunteers
- 1,320 people
- Sponsor
- University of California, San Francisco
Anaphylactic Reaction, Anaphylaxis
Steroid Use in Treatment of Allergic Reactions to Food
In this study, the investigators want to find out whether a specific medication commonly used for severe allergic reactions is really necessary.
- Conditions
- Anaphylactic Reaction, Anaphylaxis, Allergy in Children, IgE Mediated Food Allergy
- Trial name
- SAFARI (NCT07341776)
- Testing
- Antihistamines, Systemic corticosteroids, Adrenaline (rescue medication)
- Where
- 2 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Johannes Trueck
Sepsis
Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care
Sepsis is a life-threatening complication of infection that can be difficult to recognize and treat promptly. Timely administration of antibiotics for emergency department (ED) patients with sepsis is challenging.
- Trial name
- Code Sepsis (NCT04148989)
- Testing
- Code Sepsis protocol (full implementation)
- Where
- 3 sites in United States
- Volunteers
- 180,402 people
- Sponsor
- Intermountain Health Care, Inc.
Mass Casualty Incident Preparedness, Simulation-Based Medical Education
Mass-Casualty Incident - Prehospital Emergency Response
The goal of this study was to learn whether the MCIPHER memory aid could help first-year resident doctors manage a simulated mass-casualty incident.
- Trial name
- MCIPHER (NCT07838441)
- Testing
- Standard Mass-Casualty Incident Curriculum, MCIPHER mnemonic pre-brief, Tabletop Simulation
- Where
- United Arab Emirates
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Community-acquired Pneumonia, Dyspnea
Chest CT-scan for the Diagnosis of Community-acquired Pneumonia
Primary objective : to estimate impact of CT-scan on diagnostic for emergency department (ED) patients with suspected Community-acquired Pneumonia (CAP).
- Trial name
- PACSCAN (NCT01574066)
- Testing
- Chest CT-scan
- Where
- 4 sites in France
- Volunteers
- 339 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke
Prehospital Study at the Universitair Ziekenhuis Brussel II
Interventional prospective randomized open blinded end-point (PROBE) single-center clinical trial on the evaluation of the efficacy, safety, feasibility, reliability, and cost-effectiveness of in-ambulance telemedicine for…
- Trial name
- PreSSUB II (NCT02270541)
- Testing
- Telemedicine
- Where
- Belgium
- Volunteers
- 140 people
- Sponsor
- Universitair Ziekenhuis Brussel
Adverse Drug Event
Adverse Drug Events at Emergency Department
Emergency departments (EDs) are a crucial element of the health care systems at interface between hospital and communities. The goals of the ED are to make an initial diagnosis and deliver urgent and critical care 24 hour per day…
- Trial name
- ADEsED (NCT03442010)
- Testing
- Detection of adverse drug events
- Where
- France
- Volunteers
- 13,453 people
- Sponsor
- University Hospital, Montpellier
Human Immunodeficiency Virus
Mater-Bronx Rapid HIV Testing Project.
In the M-BRiHT study we aim to implement a programme of opportunistic HIV screening in the Emergency Department, Mater Misericordiae University Hospital.
- Trial name
- M-BRiHT (NCT01778374)
- Testing
- No participant choice of counselor, Participant choice of counselor
- Where
- Ireland
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Hypertension, Hyperglycemia
Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial
The objective of this study is to pilot a multifaceted, optimized intervention for metabolic syndrome (MetS) in emergency department patients to establish feasibility.
- Conditions
- Hypertension, Hyperglycemia, Dyslipidemia, Metabolic Syndrome
- Trial name
- METS (NCT07119658)
- Testing
- Composite intervention to address MetS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University