Clinical trials: Medicine, Emergency
Drug Interactions, Hypertension
Interactions Between Antihypertensive Drugs and Drugs Prescribed in the Emergency Room
Drug interactions (IFF) are events that occur when multiple drugs are administered at the same time to an individual. People with arterial hypertension generally require therapeutic regimens based on 2 or more drugs for their…
- Trial name
- NCT05140590
- Where
- Mexico
- Volunteers
- 53 people
- Sponsor
- Instituto Mexicano del Seguro Social
Patient Discharge
Discharge Planning for Elderly Patients in the Emergency Department: Use of a Brief Phone Call After Discharge to Improve Medication Utilization and Physician Follow-up
The investigators hypothesize that the acquisition and correct utilization of medications as well as arranging and attending follow-up appointments will improve as a result of a phone call intervention 1-3 days after elderly…
- Trial name
- NCT01207180
- Testing
- Phone call follow-up, Satisfaction survey, Control group --- no intervention
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- University of North Carolina, Chapel Hill
Cellulitis, Skin Disease, Infectious
Naproxen Versus Placebo as Adjunct Treatment of Cellulitis
Cellulitis is a painful bacterial skin infection commonly seen in Canadian emergency departments. Cellulitis has a negative impact on patients' quality of life and productivity.
- Conditions
- Cellulitis, Skin Disease, Infectious, Infection, Skin and Soft Tissue Infections (SSTIs)
- Trial name
- NVP (NCT07665476)
- Testing
- enteric-coated naproxen, Cephalexin Tablets
- Where
- Canada
- Volunteers
- 884 people
- Sponsor
- Ottawa Hospital Research Institute
Constipation Drug Induced
Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation
The purpose of this study is to compare the efficacy of subcutaneous versus oral mu-opioid receptor antagonist therapy in opioid induced constipation that is refractory to other bowel regimens.
- Trial name
- NCT03523520
- Testing
- Methylnaltrexone Bromide 150 mg Oral Tablet, Methylnaltrexone Bromide 12 MG/0.6 ML Subcutaneous Solution [RELISTOR]_#1, Naloxegol 25 MG Oral Tablet
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Missouri-Columbia
Intoxication; Opioid
Early Addiction Care Pathway After Acute Drug Intoxication in Emergency Departments
Acute intoxication with psychoactive substances represents a major public health issue and a frequent reason for emergency department (ED) visits.
- Trial name
- IPAIS (NCT07738835)
- Testing
- Structured early addiction care, Not structured early addiction care
- Where
- 4 sites in France
- Volunteers
- 266 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Renal Colic
Transcutaneous Electrical Nerve Stimulation Treatment of Renal Colic
The aim of the present trial was to investigate the analgesic efficacy and safety of Transcutaneous electrical nerve stimulation treatment in patients with renal colic within the emergency department.
- Trial name
- NCT03237208
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Adiyaman University Research Hospital
Adverse Drug Events, Adverse Drug Reactions
Pharmacogenetic Testing Among Home Health Patients
Patients meeting eligibility criteria will be randomized into two groups, one receiving pharmacogenetic testing and the other not receiving pharmacogenetic testing.
- Conditions
- Adverse Drug Events, Adverse Drug Reactions, Drug Interaction Potentiation, Drug Metabolism, Poor, CYP2D6-RELATED
- Trial name
- NCT02378220
- Testing
- Pharmacogenetic testing
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Genelex Corporation
Medication Compliance, Drug-Related Side Effects and Adverse Reactions
Improving Drug Safety in Emergency Patients -a Randomized Controlled Trial
Aim/Objective: Investigate the effect of implementing a working model for performing medication reconciliation (MR) and medication review (MRe) in the emergency department (ED), on readmissions, patient safety and efficiency of…
- Conditions
- Medication Compliance, Drug-Related Side Effects and Adverse Reactions, Remission, Medicinal Substance; Adverse Effect
- Trial name
- EPIMERR (NCT03123640)
- Testing
- Medication reconciliation and medication review
- Where
- Norway
- Volunteers
- 806 people
- Sponsor
- Diakonhjemmet Hospital
Drug Abuse
Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department
Screening, brief interventions, and referral to treatment (SBIRT) for drug use/abuse offers opportunities for early detection, brief intervention/treatment, and substance use treatment referrals for patients in medical settings.
- Trial name
- NCT01113190
- Testing
- Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET)
- Where
- United States
- Volunteers
- 878 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Drug Related Problems, Pharmaceutical Care
Integral Management of Healthcare Problems Related With Drugs in Polimedicated Patients: Medication Code
Background: Although Drug- related Problems (DRPs) in polimedicated patients are a major public health problem in western countries and many of them have been considered avoidable, secondary and primary prevention policies have…
- Trial name
- NCT03607097
- Testing
- Secondary prevention program for drug related problems
- Where
- Spain
- Volunteers
- 808 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Bronchiolitis, Viral Bronchiolitis
Internal Jugular Vein Respiratory Variability as a Marker of Disease Severity in Infant Bronchiolitis
This prospective observational cohort study evaluates whether respiratory-cycle variation in internal jugular vein (IJV) diameter, measured by point-of-care ultrasound, correlates with clinical disease severity in infants 1-23…
- Conditions
- Acute Bronchiolitis, Viral Bronchiolitis, Respiratory Syncytial Virus Infections
- Trial name
- IJV-BRONCH (NCT07778225)
- Testing
- Point-of-Care Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Eskisehir Osmangazi University
Sedation and Analgesia, Side Effect of Drug
The Effect of Ondansetron During Intramuscular Ketamine Use in Children: A Trial in Emergency Department
The purpose of this study is to evaluate the anti-emetic effect of oral ondansetron. For this evaluation, the investigators will perform a multi-center, double-blind, placebo-controled, randomized study.
- Trial name
- NCT01477242
- Testing
- Ondansetron
- Where
- South Korea
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Medication Administration, Medication Errors
Decreasing Medication Errors by Caregivers Using a Health Literacy Intervention
Giving medications to children can be confusing; studies have shown that caregivers make dosing administration errors up to 50% of the time.
- Trial name
- NCT01294501
- Testing
- Medication administration educational module
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Columbia University
Healthy
Impact of Stress and Sleep Management on Emergency Professionals
The investigators hypothesize that a recovery management program could have an impact on emergency nurses and physicians by improving their sleep and reducing their psychological and physiological responses when dealing with…
- Trial name
- REST (NCT05251246)
- Testing
- recovery management program
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Opioid Use, Opioid Abuse
Rural Expanded Access to OUD Care & Linkage Using Toxicologists for Telehealth Initiated Treatment
The overarching goal of this project is to increase the availability of OUD treatment in rural counties in the state of Georgia by using Emergency Department (ED)-based telehealth strategies to initiate MOUD and connect patients…
- Trial name
- REAL TTIME (NCT05711056)
- Testing
- Sociobehavioral Intervention
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Emory University
Pulmonary Embolism (Diagnosis)
Adjust-Unlikely PE
The aim of this pilot study is to assess the feasibility of a larger study to determine the Adjust-Unlikely algorithm safety and efficiency for diagnosing PE. The pilot study objectives are to: 1.
- Trial name
- NCT05708794
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Dr. Kerstin de Wit
Firearm Injury, Pediatric Emergency Medicine
Randomized Trial to Improve Safe Firearm Storage
The goal of this clinical trial is to test the effect of providing gun locks to caregivers of children presenting to the emergency department for mental health concerns.
- Conditions
- Firearm Injury, Pediatric Emergency Medicine, Suicide and Self-harm, Mental Health Issue
- Trial name
- FARTHER (NCT05568901)
- Testing
- Lethal means counseling, Provision of Cable-style gun locks
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Elderly, Older Adults
The PAINFREE Initiative, a Stepped Wedge Cluster Randomized Trial
The PAINFREE (Improving PAIN control following FRactures; towards an Elder-friendly Emergency department) Initiative is a patient-centered multifaceted intervention which aims to improve pain management in patients 75 years and…
- Conditions
- Elderly, Older Adults, Bone Fracture, Emergency Department
- Trial name
- PAINFREE (NCT03082417)
- Testing
- Implementation
- Where
- Canada
- Volunteers
- 1,375 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Craniocerebral Trauma, Brain Injuries, Traumatic
Socio-Cultural Level, Health Literacy, and Parental CT Demand in Paediatric Minor Head Trauma
Minor head trauma is one of the most frequent reasons for paediatric emergency department visits worldwide. The PECARN (Paediatric Emergency Care Applied Research Network) clinical decision rule stratifies children with minor…
- Conditions
- Craniocerebral Trauma, Brain Injuries, Traumatic, Head Injuries, Closed
- Trial name
- NCT07655310
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Critically Ill
POC Analysis of IO Blood Samples Within Critically Ill Patients
This study aims to investigate whether point-of-care (POC) analysis of intraosseous (IO) blood samples from critically ill emergency patients are accurate enough for emergency decision making, in comparison with arterial…
- Trial name
- NCT03746496
- Testing
- point-of-care laboratory analysis
- Where
- Finland
- Volunteers
- 35 people
- Sponsor
- Helsinki University Central Hospital