Clinical trials: Medicine, Emergency
Status Epilepticus, Seizure
EEG in In-hospital Patients With Seizure or Altered Mental State
In Kuopio University Department of Clinical Neurophysiology there have been designed a fast EEG electrode, that is suitable for acute emergency use.
- Conditions
- Status Epilepticus, Seizure, Altered Mental Status
- Trial name
- NCT02383745
- Testing
- Acute EEG with fast EEG electrode
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Kuopio University Hospital
Overdose, Drug, Drug Use
ASSIST: A Surveillance Study of Illicit Substance Toxicity
There is a drug-related death crisis in Scotland. This study aims to collaborate with Public Health Scotland in order to assess the feasibility of introducing a surveillance system to the Emergency Department to highlight illicit…
- Conditions
- Overdose, Drug, Drug Use, Drug Abuse, Drug Toxicity
- Trial name
- ASSIST (NCT05329142)
- Testing
- Surplus sample toxicology analysis
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- NHS Greater Glasgow and Clyde
Vascular Access Complication
Ultrasound Guided Versus Landmark Guided Arterial Line Placement by Emergency Medicine Interns
Critically ill patients in the emergency department commonly require arterial line placement for continuous direct blood pressure monitoring, frequent arterial blood gas sampling, and frequent blood sampling.
- Trial name
- NCT03326739
- Testing
- Arterial Line Placement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Temple University
General Medicine, Emergency Medicine
Improving Follow-Up for Discharged Emergency Care Patients
This study's purpose is to test the effects of an electronic health intervention platform developed by Epharmix (also known as CareSignal), which features two-way SMS text messages and phone calls intended to improve clinical…
- Conditions
- General Medicine, Emergency Medicine, Mobile Health
- Trial name
- NCT03002311
- Testing
- Epharmix/CareSignal eHealth
- Where
- United States
- Volunteers
- 327 people
- Sponsor
- Washington University School of Medicine
Cardiac Arrest, Pulseless Electrical Activity
Surviving PEA in Roanoke (SPEAR) Study
The Carilion Clinic and Virginia Tech Carilion School of Medicine, in conjunction with Roanoke Fire-EMS, Botetourt County Department of Fire \& EMS and Salem Fire-EMS, are studying the outcomes of patients experiencing Pulseless…
- Trial name
- SPEAR (NCT05283850)
- Testing
- High Calcium, Low Sodium (HCLS) Crystalloid Therapy, High Calcium, High Sodium (HCHS) Crystalloid Therapy
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- Carol Bernier
Stroke Acute, Emergency Medical Services
Sex diffErences in prehoSpitAl Stroke MEdicine
Background: Stroke is a leading cause for individual, family and societal harm with huge health-economic impact. Immediate and correct prehospital acute stroke pathway initiation is key for treatment success.
- Conditions
- Stroke Acute, Emergency Medical Services, Sex Characteristics, Prehospital Setting
- Trial name
- SESAME (NCT06865950)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Universität des Saarlandes
Burnout, Professional
Identifying Mental Health Distress in EM Physicians
This project seeks to develop and test provider-centered strategies that improve the detection and facilitate the treatment of physiologic and mental health symptoms in emergency medicine physicians.
- Trial name
- NCT05606887
- Testing
- Wearable Device and Ecological Momentary Assessments
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Regional Anaesthesia, Emergency Medicine
Comparative Evaluation of Ultrasound-Guided Femoral Nerve Block Training With Low-Fidelity Low-Cost Simulation Model Among Junior Doctors in Department of Emergency Medicine USM.
To study the effectiveness of low-fidelity ultrasound-guided femoral nerve block training interventions score in knowledge and skills performance among junior doctors in the Department of Emergency Medicine Universiti Sains…
- Trial name
- NCT07604506
- Testing
- Low-fidelity ultrasound-guided femoral nerve block simulation training
- Where
- Malaysia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Virtual Reality Simulation, Simulation-based Medical Education
Immersive Virtual Reality Simulation-Effects of Self-Guided Versus Facilitator-Guided Debriefing
The goal of this clinical trial is to find out whether self-guided and facilitator-guided virtual reality (VR) simulations are equally effective in helping medical students learn how to manage and treat critically ill children.
- Conditions
- Virtual Reality Simulation, Simulation-based Medical Education, Pediatric Emergency Medicine, Immersive Virtual Reality
- Trial name
- NCT06956833
- Testing
- Ìmmersive virtual reality simulation with self-guided debriefing, Ìmmersive virtual reality simulation with facilitator-guided debriefing
- Where
- Denmark
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Dehydration
Study of Subcutaneous Rehydration With Recombinant Human Hyaluronidase for Infants and Children
The aim of the study is to evaluate the safety, effectiveness and ease of use of subcutaneous (SC) rehydration using HYLENEX-augmented SC infusion of fluids and electrolytes for the rehydration of pediatric patients with mild to…
- Trial name
- INFUSE-PR (NCT00477152)
- Testing
- hyaluronidase (human recombinant)/rehydration fluid
- Volunteers
- 52 people
- Sponsor
- Baxter Healthcare Corporation
Opioid Use Disorder, Opioid Overdose
A Bundled Intervention to End Opioid Overdoses
Opioid overdose deaths have reached historically high records in the United States and are particularly concentrated among patients after emergency department (ED) discharge.
- Trial name
- B-CARE (NCT07485335)
- Testing
- Bundled intervention (Experimental), control group, Buprenorphine (Experimental)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Alabama at Birmingham
Asthma, Pediatric ALL
Inhaled Steroids for Pediatric Asthma at Pediatric Emergency Medicine Discharge
This study evaluates the initiation of inhaled corticosteroids upon discharge from the pediatric emergency room in children under 18 presenting with asthma exacerbation.
- Trial name
- NCT03369847
- Testing
- budesonide, beclomethasone
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Asthma
RCT of a Written Action Plan vs. Usual Care in Children With Acute Asthma
The objective of the proposed large, high-intensity, randomised controlled trial is to evaluate the real-life effectiveness of providing a written action plan to asthmatic children discharged from the emergency department (ED) or…
- Trial name
- NCT00381355
- Testing
- Written Action Plan for Acute Asthma
- Where
- Canada
- Volunteers
- 218 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Penicillin Allergy, Pediatric Emergency Medicine
Oral Challenge in the Pediatric ED
Our primary objective was to demonstrate the feasibility of utilizing a novel penicillin allergy questionnaire in the PED to identify a low-risk group of patients who will complete an oral challenge in the PED to test for an…
- Trial name
- OPEN (NCT03404804)
- Testing
- Amoxicillin
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Medical College of Wisconsin
Head Injury, Traumatic Brain Injury
Selective CT for Anticoagulated Head Injured Patients
The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications. The objectives are to: 1.
- Conditions
- Head Injury, Traumatic Brain Injury, Intracranial Hemorrhage, Traumatic, Blunt Head Injury
- Trial name
- Can-SCAHn (NCT05364749)
- Where
- 7 sites in Canada
- Volunteers
- 4,000 people
- Sponsor
- Dr. Kerstin de Wit
Triage, Emergency Department Triage
Impact of Point-of-care Lactate Testing as Triage Supplement on Patient Management Using Manchester Triage System
Although the Manchester Triage System (MTS) is widely used and validated internationally, it has some limitations. Its accuracy is moderate, especially for children and the elderly.
- Conditions
- Triage, Emergency Department Triage, Emergency Department Overcrowding, Emergency Medicine
- Trial name
- NCT07123857
- Testing
- re-triage
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Medical Centre Maribor
Uncertainty, Communication Research
Trial of Simulation-based Mastery Learning to Communicate Diagnostic Uncertainty
The goal of this study is to teach emergency medicine resident physicians to communicate more effectively with patients at the time of emergency department discharge in the setting of diagnostic uncertainty (i.e.
- Conditions
- Uncertainty, Communication Research, Emergency Medicine
- Trial name
- NCT04021771
- Testing
- Educational Curriculum Intervention
- Where
- 2 sites in United States
- Volunteers
- 109 people
- Sponsor
- Thomas Jefferson University
Trauma
Accuracy and External Validation of mREMS in Road Traffic Injuries
The goal of this prospective observational study is to assess the accuracy and external validation of the Modified Rapid Emergency Medicine Score (mREMS) in predicting outcomes for patients with road traffic injuries (RTIs)…
- Trial name
- AVE-MREMS (NCT06740409)
- Where
- Iraq
- Volunteers
- 292 people
- Sponsor
- Al-Nahrain University
Pediatric Emergency Medicine, Resuscitation
A Clinical Trial to Study the Feasibility and Acceptability of an App to Support Pediatric Resuscitation
The goal of this clinicial trial is to test the acceptability and feasibility of linear cognitive aid intervention to support EMS teams in responding to pediatric emergencies.
- Conditions
- Pediatric Emergency Medicine, Resuscitation, Pediatrics, Emergency Medical Services
- Trial name
- NCT06768099
- Testing
- Linear Cognitive Aid
- Where
- 2 sites in United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Schizophrenia, Schizoaffective Disorder
PROFILe3: Epidemiologic Survey in Patients With Schizophrenia or Schizoaffective Disorders
The purpose of this study is to evaluate epidemiological characteristics of patients that experience relapse and need an admission in psychiatric acute units across Spain.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- NCT00399334
- Testing
- antipsychotic medications
- Volunteers
- 1,607 people
- Sponsor
- Janssen-Cilag, S.A.