Clinical trials: Medium-chain Triglyceride
Healthy
Effect of MCT Emulsification on Ketogenesis in Human Adults
Lower brain glucose uptake is present before the onset of cognitive deterioration and may increase the risk of cognitive decline in Alzheimer's disease. Ketones are the brain's main alternative energy substrates.
- Trial name
- NCT02409927
- Testing
- MCT oil 10g, MCT homogenate 10g, Control
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Cholestasis, Jaundice, Obstructive
SMOFlipid to Lessen the Severity of Neonatal Cholestasis
Parenteral nutrition (PN) provides intravenous nutritional supplementation for infants unable to absorb adequate enteral nutrients secondary to insufficient intestinal length or function.
- Trial name
- NCT02721277
- Testing
- SMOFlipid
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Florida
Parkinson's Disease
Acute Effects of Medium Chain Triglyceride (MCT) Nutritional Ketosis on Parkinson's Disease (PD) Symptoms and Biomarkers (MCT-PD)
Background: The ketogenic diet uses fats as a person's major energy source rather than carbohydrates. There is increasing interest in using this diet to treat neurodegenerative disorders like Parkinson's disease.
- Trial name
- NCT04584346
- Testing
- Liquigen MCT oil, Standard American Diet
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Prediabetic State
Medium Chain Triglycerides and Aerobic Exercise on Ketone Production in Women With or Without Prediabetes
The aim of this study is to compare the effect on ketone production of dietary an MCT supplement combined or not with physical exercise in two groups of women (N=10/group), healthy adults and patients with prediabetes.
- Trial name
- MCT+AE (NCT02678390)
- Testing
- MCT, MCT+ aerobic exercise, Aerobic exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Healthy Adults
Comparing the Ketogenic Effect of Coconut Oil and Different MCTs
The aim of this study is to compare the ketogenic effect of coconut oil and three MCT oils (60-40 , tricaprylin and triheptanoate) on the production of ketones in healthy adults.
- Trial name
- MCT-Coco (NCT02679222)
- Testing
- Coconut oil, Coconut oil + MCT, MCT
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Candida Infection, Premature Infant
Effect of Medium Chain Triglyceride Intake on Colonization of Preterm Infants With Candida
This study evaluates whether adding a dietary supplement similar to coconut oil (MCT oil) to feedings in premature infants will reduce the amount of yeast (Candida) detectable in their stool.
- Trial name
- NCT03630770
- Testing
- Medium-Chain Triglyceride (MCT) Oil
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Joseph Bliss
Healthy Adults
Evaluation of the Ketogenic Potential of Different Diet Supplements
Evaluate the capacity of different dietary supplements to increase ketone production in healthy adults.
- Trial name
- NCT02693106
- Testing
- Control, Leucine, Butyrate -
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Preterm Infants, Parenteral Nutrition n-3 Fatty Acids
Comparison of Two Different Lipid Emulsions for Parenteral Nutrition in Preterm Infants
The study shall provide evidence for the save and efficient use of a fish oil containing lipid emulsion in parenteral nutrition of preterm infants.Safety will be assessed by monitoring hepatological and hematological laboratory…
- Trial name
- NCT00497289
- Testing
- Lipofundin MCT/LCT 20 %, Lipidem 20%
- Where
- 2 sites in Germany
- Volunteers
- 48 people
- Sponsor
- B. Braun Melsungen AG