Clinical trials: Meibomian Gland Dysfunction (MGD)
Meibomian Gland Dysfunction of Unspecified Eye, Unspecified Eyelid
Analysis of Postoperative Ocular Surface Changes and Intervention Effect After PPV in MGD Dry Eye Patients
AIM: To observe ocular surface changes after phacovitrectomy in patients with mild to moderate meibomian gland dysfunction (MGD)-type dry eye and track clinical treatment response using a Keratograph 5M and a LipiView…
- Trial name
- NCT05771194
- Testing
- Routine preoperative and postoperative anti-infection therapy, artificial tear therapy, Cleaning, hot compresses and massage of the meibomian gland
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Palpebral Pathologies, Ocular Surface Disease
Management of Eyelid Disorders by Ophthalmologists in Usual Medical Practice
The purpose of this study is to determine the incidence and characteristics of eyelid inflammatory disorders during general ophthalmological consultations and to demonstrate association between palpebral pathologies and ocular…
- Conditions
- Palpebral Pathologies, Ocular Surface Disease, Meibomian Gland Dysfunction
- Trial name
- MEIBUM (NCT01552174)
- Where
- 2 sites in Germany, Spain
- Volunteers
- 185 people
- Sponsor
- Laboratoires Thea
Meibomian Gland Dysfunction, Dry Eye
Randomized Controlled Trial of Long-term Treatment Effectiveness for Meibomian Gland Dysfunction (MGD) and Dry Eye
The study objective is to evaluate the long-term treatment effectiveness for adult patients with meibomian gland dysfunction (MGD) and evaporative dry eye by: 1) comparing the LipiFlow® System to a standardized daily warm…
- Trial name
- NCT01521507
- Testing
- LipiFlow System, Warm Compress Therapy + Lid Scrub
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- TearScience, Inc.
MGD-Meibomian Gland Dysfunction
The Effect of Meibomian Glands Massage on Signs and Symptoms of Dry Eye
The study aims to investigate whether combined treatment of MGD massage and artificial tears will improve signs and symptoms of dry eye compared to artificial tears alone.
- Trial name
- NCT03104894
- Testing
- Meibomian Glands Massage, Meibomian Massage device
- Where
- Israel
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Meibomian Gland Dysfunction (Disorder)
TearCare MGX™ System With and Without Warming Hold
TearCare is an office-based thermal therapeutic eyelid technology cleared by the US Food and Drug Administration for the treatment of evaporative dry eye disease due to meibomian gland dysfunction.
- Trial name
- XTEND (NCT07365735)
- Testing
- localized heat therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Sight Sciences, Inc.
Meibomian Gland Dysfunction (MGD)
The Effect of an Eyelid Warming Device for the Management of Meibomian Gland Dysfunction
Along the edge of the eyelids, there are glands (meibomian glands) that produce and deliver oils (meibum) onto the tear film. These oils serve to slow down the evaporation of tears.
- Trial name
- Hummingbird (NCT02284997)
- Testing
- MGDRx® EyeBag
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- University of Waterloo
Dry Eye Disease, Meibomian Gland Dysfunction
Feasibility of IPL Combined With RF for Treatment of DED Due to MGD
The purpose of this single-arm pilot study is to evaluate the feasibility and safety of combination therapy of intense pulsed light (IPL) and (Radiofrequency) RF for treatment of Dry eye disease (DED) due to Meibomian gland…
- Trial name
- NCT05487547
- Testing
- IPL_RF_MGX
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Lumenis Be Ltd.
Dry Eye, Ocular Graft vs Host Disease
Brimonidine Eye Drops for Treatment of Ocular Graft-vs-Host Disease (oGVHD)
The objective of this study is to establish whether patients with dry eye disease (DED) are able to tolerate receiving Brimonidine: 0.15% eye drops two times a day for twelve weeks (primary tolerability objective) and to…
- Conditions
- Dry Eye, Ocular Graft vs Host Disease, Meibomian Gland Dysfunction
- Trial name
- NCT02975557
- Testing
- Brimonidine 0.15%, Brimonidine 0.075%
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Sandeep Jain, MD
Cataracts, Meibomian Gland Dysfunction (MGD)
A Post-Market Evaluation of LipiFlow Treatment in Cataract Surgery Practice
This is a post-market, prospective, randomized, multi-center, bilateral, open-label, cross-over, comparative clinical study. Study group will undergo preoperative LipiFlow treatment and Control group will not receive preoperative…
- Trial name
- NCT03708367
- Testing
- LipiFlow Thermal Pulsation System
- Where
- 5 sites in United States
- Volunteers
- 117 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
MGD-Meibomian Gland Dysfunction
Therapeutic Effectiveness of Different Machines in Intense Pulsed Light Treatment of Meibomian Gland Dysfunction
This study aimed to determine the therapeutic effectiveness of different machines in intense pulsed light (IPL) treatment of meibomian gland dysfunction (MGD).
- Trial name
- MGD (NCT06034626)
- Testing
- Intense pulsed light, 0.3% hyaluronic acid eye drops
- Where
- 3 sites in China
- Volunteers
- 216 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Evaporative Dry Eye Disease, Meibomian Gland Dysfunction
Clinical Study Using Eye Lipid Mobilizer (ELM) With Heat and Vibration To Treat Evaporative Dry Eye Disease
The goal of this clinical trial is to evaluate the Eye Lipid Mobilizer (ELM) for the treatment of evaporative dry eye disease associated with meibomian gland dysfunction.
- Trial name
- ELM (NCT06242860)
- Testing
- ELM
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Eyedetec Medical, Inc.
Dry Eye
Effect of Intense Pulse Light (IPL) Treatment on Tear Film Osmolarity
Evaluate changes in tear film osmolarity and other DED signs/symptoms following treatment with IPL.
- Trial name
- NCT02992535
- Testing
- Intense Pulse Light Energy delivery (IPL)
- Volunteers
- 60 people
- Sponsor
- Carones Ophthalmology Center
Evaporative Dry Eye
iLux Treatment for Meibomian Gland Dysfunction (MGD)
The purpose of this study is to assess changes in meibomian gland function and evaporative dry eye symptoms after treatment with the iLux medical device.
- Trial name
- NCT03055650
- Testing
- iLux 2020 System
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Tear Film Innovations, Inc.
Meibomian Gland Dysfunction, Evaporative Dry Eye
Dextenza With ILUX for Treatment of MGD
To evaluate the benefit of treatment with a physician administered intracanalicular dexamethasone insert in evaporative dry eye disease (DED) patients with meibomian gland disfunction (MGD) and underlying inflammation undergoing…
- Trial name
- NCT04658927
- Testing
- Dexamethasone, 0.4mg, Prednisone acetate, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Warrenville Eyecare
Dry Eye, MGD-Meibomian Gland Dysfunction
Comparative Effects of USB-Powered Warm Compress and Self-Heating Eye Mask in the Management of Meibomian Gland Dysfunction
Why was this study done? People with Meibomian Gland Dysfunction (MGD) often have dry, irritated eyes because the tiny oil glands in their eyelids do not work properly.
- Trial name
- NCT07618169
- Testing
- USB-Powered Warm Compress, Self-Heating Eye Mask
- Where
- Saudi Arabia
- Volunteers
- 15 people
- Sponsor
- King Saud University
Demodex Blepharitis, Meibomian Gland Dysfunction (MGD)
Effectiveness of Low Level Light Therapy and Intense Pulse Light on Mite Count as Adjuntive Therapies in Demodex Blepharitis Using Artificial Intelligent Program (Ai-Demodex)
Primary Objective: To evaluate the efficacy of LLLT, IPL, and IPL + LLLT in re ducing demodex count in patients with Demodex Blepharitis.
- Trial name
- Ai-Demodex (NCT07169461)
- Testing
- The blue MY MASK-E, IPL, Mechanical with pharmacological treatment
- Where
- Thailand
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Meibomian Gland Dysfunction
Evaluation of AZR-MD-001 in Patients With Meibomian Gland Dysfunction (MGD)
AZ202001 is a multicenter study of AZR-MD-001 ointment and AZR-MD-001 vehicle in patients with Meibomian Gland Dysfunction (MGD)
- Trial name
- NCT04391959
- Testing
- AZR-MD-001 Active, AZR-MD-001 Vehicle
- Where
- 5 sites in Australia, New Zealand
- Volunteers
- 31 people
- Sponsor
- Azura Ophthalmics
Dry Eye Syndromes
Feasibility of IPL for Reducing Dry Eye Symptoms Caused by MGD
The purpose of this study is to evaluate if, in patients with meibomian gland dysfunction (MGD), treatment with the Lumenis M22 Intense Pulsed Light (IPL) system causes a reduction in dry eye symptoms post-treatment, compared to…
- Trial name
- NCT02621593
- Testing
- M22-IPL
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Lumenis Be Ltd.
Dry Eye Syndrome
Efficacy Comparison of Two Kinds of Treatment in Treating Dry Eye Caused by Meibomian Gland Dysfunction
This study aims to evaluate the efficacy of intense pulsed light in treating dry eye caused by meibomian gland dysfunction and make a comparison between the traditional treatment.
- Trial name
- NCT02958514
- Testing
- intense pulsed light, Tobramycin and Dexamethasone Ophthalmic Ointment
- Volunteers
- 20 people
- Sponsor
- Peking University Third Hospital
Meibomian Gland Dysfunction
The Efficacy of an Ocular Emulsion in Meibomian Gland Dysfunction
The aim of this study will be to determine the efficacy of this novel, lipid-containing artificial tear on the signs and symptoms of meibomian gland disease.
- Trial name
- NCT01207752
- Testing
- Systane Balance, Optive Lubricant Eye Drops
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University