Clinical trials: Meibomian Gland Dysfunction (MGD)
Meibomian Gland Dysfunction, Evaporative Dry Eye Disease
Comparison Between iLux and LipiFlow in the Treatment of Meibomian Gland Dysfunction (MGD): A 12-month, Multicenter Study
The purpose of this post-approval study is to demonstrate that iLux treatment offers comparable treatment effectiveness to LipiFlow for MGD treatment at 12 months post single treatment.
- Trial name
- NCT03956225
- Testing
- Systane iLux® Dry Eye System, LipiFlow® Thermal Pulsation System
- Where
- 15 sites in United States
- Volunteers
- 299 people
- Sponsor
- Alcon Research
Evaporative Dry Eye Disease
Comparative Efficacy Study to Demonstrate the Non-inferiority of I-DROP® MGD Versus 2 Competitor Eye Drops in Managing Evaporative Dry Eye
A Pilot Comparative study between I-DROP MGD vs two commercially available lubricant eye drops for the management of evaporative dry eye
- Trial name
- NCT06686368
- Testing
- I-DROP MGD, Theloze Duo, Systane Complete PF
- Volunteers
- 60 people
- Sponsor
- I-MED Pharma
MGD-Meibomian Gland Dysfunction, Positron-Emission Tomography
PET-CT Imaging Features of Meibomian Glands
Analysis the results of Dry eye analysis results and PET-CT imaging comprehensively
- Conditions
- MGD-Meibomian Gland Dysfunction, Positron-Emission Tomography, Dry Eye
- Trial name
- NCT06324890
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Meibomian Gland Dysfunction, Dry Eye
A Multicenter Study Evaluating AZR-MD-001 in Patients With Meibomian Gland Dysfunction and Evaporative Dry Eye Disease (DED)
AZ201801 is a multicenter study of AZR-MD-001 ointment and AZR-MD-001 vehicle in patients with Meibomian Gland Dysfunction (MGD) and evaporative Dry Eye Disease (DED)
- Trial name
- NCT03652051
- Testing
- AZR-MD-001 Low Dose, AZR-MD-001 Mid Dose, AZR-MD-001 High Dose
- Where
- 30 sites in Australia, Canada and 1 more
- Volunteers
- 321 people
- Sponsor
- Azura Ophthalmics
Dry Eye Syndromes, Meibomian Gland Dysfunction
Therapeutic Efficacy and Safety of Non-Invasive RF Treatment in Refractory MGD
The goal of this prospective, 24-week, double-masked, randomized, sham-controlled clinical trials to compare clinical efficacy and safety of RF and MGX with MGX alone in patients with meibomian gland dysfunction-related dry eye…
- Trial name
- NCT06220474
- Testing
- The Thermage FLX System
- Where
- 2 sites in Hong Kong
- Volunteers
- 112 people
- Sponsor
- The University of Hong Kong
Meibomian Gland Dysfunction (MGD)
Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunction
This research study evaluates a prescription eye drop called Vevye® (cyclosporine 0.1%) for adults who have meibomian gland dysfunction (MGD), a common eye condition that can cause dry, irritated, or burning eyes.
- Trial name
- NCT07224529
- Testing
- Vevye(Cyclosporine 0.1% Ophthalmic Solution)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Alabama at Birmingham
Meibomian Gland Dysfunction (MGD)
Treatment of Meibomian Gland Dysfunction
The current study aims to test the efficacy of treatment for a device that utilises a thermal pulsation system, which applies heat from the inner surface of the eyelids (Lipiflow) in patients suffering from meibomian gland…
- Trial name
- NCT01683318
- Testing
- Thermal Pulsation therapy
- Where
- Singapore
- Volunteers
- 25 people
- Sponsor
- Singapore National Eye Centre
Meibomian Gland Dysfunction
Vectored Thermal Pulsation, Intense Pulsed Light, and Eyelid Warm Compress Therapies for MGD
Meibomian gland dysfunction (MGD), closely associated with Dry Eye Disease (DED), is a chronic condition where terminal ducts are obstructed and/or glandular secretion changes. The efficacy of traditional treatment options, e.g.
- Trial name
- NCT05577910
- Testing
- Vectored thermal pulsation (VTP) therapy, Intense pulsed light with meibomian gland expression (IPL+MGX) therapy, Eyelid Warm Compress Therapy (EW)
- Where
- 4 sites in Hong Kong
- Volunteers
- 374 people
- Sponsor
- Chinese University of Hong Kong
Dry Eye Disease, Dry Eye Syndromes
iTear Single-center, Open-label, Single-arm Study
This study aims to evaluate the effectiveness and safety of a device, iTEAR100 Neurostimulator (the device), which is designed to help people with Dry Eye Disease (DED) who are not satisfied with using artificial tears.
- Conditions
- Dry Eye Disease, Dry Eye Syndromes, Dry Eye, Meibomian Gland Dysfunction
- Trial name
- NCT06525961
- Testing
- iTEAR100 Neurostimulator
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Meibomian Gland Dysfunction, Dry Eye
Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users
To evaluate dry eye symptoms and contact lens wearing times after a single iLux treatment by evaluating change from baseline in OSDI scores, subjective CLDEQ8 and CL wearing time questionnaires, and meibomian gland secretion…
- Trial name
- NCT05306561
- Testing
- Systane iLux thermal pulsation treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Periman Eye Institute
Dry Eye Disease (DED), MGD-Meibomian Gland Dysfunction
The Effect of Eyelid Support Plate Assisted Eyelid Massage on Meibomian Gland Dysfunction: a Randomized Controlled Trial
This study aims to conduct a randomized controlled clinical trial to compare the efficacy of a new type of massage device - eyelid support plate and glass rod assisted eyelid massage in improving MGD related dry eye symptoms, and…
- Trial name
- NCT07633938
- Testing
- eyelid support plate assisted eyelid massage, glass rod assisted eyelid massage
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Meibomian Gland Dysfunction, Dry Eye Disease
Clinical Study Evaluating Nordlys™ SWT IPL for Dry Eye Disease (DED) Due to MGD
Clinical Study Evaluating Nordlys™ System with Selective Waveband Technology (SWT)® Intense Pulsed Light (IPL) Applicators for Dry Eye Disease (DED) due to Meibomian Gland Dysfunction (MGD).
- Trial name
- NCT06064071
- Testing
- Nordlys SWT IPL, Meibomian Gland Expression (MGX)
- Where
- 3 sites in United States, Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Meibomian Gland Dysfunction, Dry Eye Disease
Fingerprick Autologous Blood (FAB) in Mebomian Gland Dysfunction (MGD)
Dry eye disease remains one of the most common complaints seen in ophthalmic clinics. Causes of dry eye are multifactorial, with the most common cause of evaporative dry eye disease being meibomian gland dysfunction (MGD).
- Trial name
- NCT02943382
- Testing
- Fingerprick autologous blood (FAB)
- Volunteers
- 20 people
- Sponsor
- Bedford Hospital NHS Trust
Meibomian Gland Dysfunction
Clinical Efficacy of Hormone Replacement Therapy in Treating Perimenopausal Women With MGD
This project aims to evaluate the possible relationship between MGD and HRT in perimenopausal women
- Trial name
- NCT04962386
- Testing
- Hormone replacement therapy
- Where
- 2 sites in China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cataract
Meibomian Gland Dysfunction (MGD) and Tear Cytokines After Cataract Surgery According to Preoperative Meibomian Gland Status
To investigate the possible mechanisms by which cataract surgery aggravates meibomian gland dysfunction (MGD), the investigators evaluated the changes in tear cytokines and ocular surface parameters after cataract surgery…
- Trial name
- NCT02411487
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Dry Eye Disease
A Study to Evaluate the Safety and Effectiveness of Perfluorohexyloctane Eye Drops on Treatment of Dry Eye Disease (DED) Related to Meibomian Gland Dysfunction (MGD)
Perfluorohexyloctane eye drops is the only drug in China approved for treating Dry Eye Disease (DED) related to Meibomian Gland Dysfunction (MGD), its efficacy and safety in the clinical practice of treating DED related to MGD in…
- Trial name
- NCT07457021
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xiamen Ophthalmology Center Affiliated to Xiamen University
Meibomian Gland Dysfunction
Efficacy and Safety of Thermic Devices in the Treatment of Meibomian Gland Dysfunction
Dry eye syndrome is a common eye disease that affects 1 to 2 out of 10 persons around the planet. One common cause of this disease is the meibomian gland dysfunction.
- Trial name
- NCT03767530
- Testing
- Mibo Thermoflo, Warm compresses and eyelid massage
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Meibomian Gland Dysfunction
The Influence of Meibomian Gland Expression on Corneal Aberrations in MGD Patients
To evaluate the influence of corneal-aberrations before and after the meibomian gland thermal massage treatment.
- Trial name
- NCT05028491
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Wenzhou Medical University
Dry Eye, MGD-Meibomian Gland Dysfunction
Function and Morphological Characteristics of Meibomian Gland in Patients With Renal Anemia
Renal anemia refers to anemia in which the absolute or relative production of erythropoietin (EPO) is insufficient due to various kidney diseases, and uremic toxins affect erythropoietin production and its lifespan.
- Trial name
- NCT06287879
- Testing
- Dry eye examination
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhongnan Hospital
Meibomian Gland Dysfunction, Blepharitis
Pilot Study Comparing the Safety and Efficacy of Two Dosing Regimens of TP-03 for the Treatment of MGD
The purpose of this study is to compare the safety and efficacy of TP-03, 0.25%, an eyedrop, BID vs TID dosing regimens for the treatment of meibomian gland dysfunction in patients with Demodex lid infestation.
- Conditions
- Meibomian Gland Dysfunction, Blepharitis, Demodex Infestation
- Trial name
- Ersa (NCT05454956)
- Testing
- TP-03, TP-03 Vehicle
- Where
- 5 sites in United States
- Volunteers
- 39 people
- Sponsor
- Tarsus Pharmaceuticals, Inc.