Clinical trials: Melasma
Hyperpigmentation
Efficacy and Tolerability of the Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06234527
- Testing
- tested product
- Where
- Senegal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Acne, Melasma
The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis
The study is conducted to determine if image-based computer grading can of acne, melasma, rosacea and seborrheic dermatitis correlate well to expert based clinical severity grading.
- Conditions
- Acne, Melasma, Rosacea, Seborrheic Dermatitis
- Trial name
- NCT05942248
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Melasma, Post-acne Hyperpigmentation
Efficacy and Safety of a Combined Serum Containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES
The goal of this clinical trial is to evaluate the efficacy and safety of a combination serum containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES when used as a moisturizer after QS-Nd:YAG 1064 nm low-fluence laser…
- Trial name
- NCT07121439
- Testing
- a combination serum containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES, 2% hydroquinone cream
- Where
- Indonesia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Melasma
Split-face Study Comparing the Cosmetic Efficacy and Tolerability of Two Topical Products in Participants With Moderate Facial Melasma
The objective of this study is to evaluate the efficacy and tolerability of Lytera 2.0 versus 4% hydroquinone in the improvement of the appearance of moderate facial melasma.
- Trial name
- NCT02977507
- Testing
- Lytera 2.0, 4% Hydroquinone Topical Cream, SkinMedica Facial Cleanser
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Allergan
Melasma
Curcuma Xanthorriza Roxb. 10% Cream for Melasma
Melasma is an acquired hyperpigmentation disorder with a multifactorial etiology and complex pathogenesis that can significantly diminish the quality of life for affected patients.
- Trial name
- NCT06153134
- Testing
- 10% Curcuma xanthorriza Roxb., 2% Kojic Acid
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Melasma
Opsin Receptors in Melasma
Melasma is a hyperpigmentation disorder that is probably exacerbated by visible light. Opsin receptors (OPN 1, 2, 3, 4 y 5) were described in the skin, being capable of activating melanogenesis induced by visible light.
- Trial name
- NCT04417348
- Testing
- Retinoic acid
- Where
- Mexico
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Melasma
Cysteamine Compared to Hydroquinone in Melasma
Melasma is an acquired pigmentary disorder of symmetrical hyperpigmentation appearing as variable darkness macules and patches over the forehead, cheeks, and chin, even sun-exposed areas of the body.
- Trial name
- NCT05969587
- Testing
- 5% cysteamine cream, hydroquinone cream group
- Where
- Taiwan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Vitiligo, Melasma
In Vivo Imaging of Pigmentary Disorders by Reflectance Confocal Microscopy
This is a pilot study to evaluate the findings of the Reflectance Confocal Microscopy when performed in cutaneous pigmentary disorders, such as vitiligo, melasma, post-inflammatory hyper-pigmentation and hypo-pigmentation.
- Conditions
- Vitiligo, Melasma, Hyperpigmentation, Hypopigmentation
- Trial name
- NCT00771355
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Melasma
Oral Tranexamic Acid and Laser for Treatment of Melasma
Tranexamic acid and 1927 diode laser non-ablative fractionated laser for the treatment of Melasma.
- Trial name
- NCT03686787
- Testing
- Tranexamic Acid
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Laser and Skin Surgery Center of New York
Melasma
Comparison of 30% Metformin and 2% Nicotinamide Lotion With Kligman Formula in the Treatment of Melasma
Comparison of 30% Metformin and 2% Nicotinamide lotion with kligman formula in the treatment of Melasma
- Trial name
- NCT05790577
- Testing
- Metformin and Nicotinamide vs Kligman Formula
- Where
- Pakistan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ishtiaq Ahmed
Melasma
Treatment of Melasma With Glycolic Acid-Salicylic Acid Peel Versus Glycolic Acid Peel
The aim of this pilot study is to conduct a controlled comparison of the efficacy and safety of a combination peel (glycolic acid and salicylic acid) as compared to glycolic acid peel alone in the treatment of melasma.
- Trial name
- NCT02812719
- Testing
- Glycolic acid peel alone, Glycolic and salicylic acid peel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Melasma
Effectiveness and Safety of Pigment Solution Program (PSP) as Adjuvant Therapy in Melasma
This research is a clinical study with a single-blind randomized clinical trial design (randomized controlled trial) in multicenters at two Dermatology and Venereology Education centers in Indonesia.
- Trial name
- NCT06174545
- Testing
- Pigment Solution Program
- Where
- Indonesia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Melasma
Development of Products Based on Secretom From Stem Cell Conditioned Medium for Melasma Therapy
This research is a clinical study with a single-blind randomized clinical trial design (randomized controlled trial) in RSCM-FKUI This study aims to Assess the effectiveness and safety of intradermal concentrated secretome…
- Trial name
- NCT06516419
- Testing
- Concentrated secretome Injection 2mL, Tranexamic acid injection, Triple Combination Cream
- Where
- 2 sites in Indonesia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Hyperpigmentation
Efficacy and Tolerability of Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06320314
- Testing
- tested product (2039125 03)
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Melanosis
A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of Melasma
The purpose of this study is to find out the safety and effectiveness of Glycolic Acid Chemical Peels compared to Salicylic Acid Chemical Peels for the treatment of melasma.
- Trial name
- NCT01976286
- Testing
- Salicylic Acid Peels, Glycolic Acid Peels
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hyperpigmentation
Efficacy and Tolerability of Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06253468
- Testing
- tested product
- Where
- Singapore
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Melasma
Comparison Between Free Thyroxine and Thyroid Stimulating Hormone Levels on Melasma Severity
The objective of the study was to compare the level of serum FT4 and TSH in patients with mild melasma and moderate-severe melasma.
- Trial name
- NCT04359719
- Where
- Indonesia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Melanosis
A Pilot Study Testing 1064nm Q-switch Laser Versus Glycolic Acid Peels for the Treatment of Melasma
The purpose of this study is to find out the safety and effectiveness of 1064 Q-Switch Laser Therapy compared to Glycolic Acid Chemical Peels for the treatment of melasma.
- Trial name
- NCT01976273
- Testing
- 1064nm Q-switch Laser, Glycolic Acid Peels
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Melasma
Efficacy and Tolerability of Test Product Versus Cysteamine 5% in Treatment of Facial Epidermal Melasma
This interventional, randomized, investigator blinded, controlled study conducted in one centre consists in a 4-month evaluation period within the same season avoiding sunny season on 140 subjects with facial epidermal melasma.
- Trial name
- NCT06278948
- Testing
- Group TP, Group CYS
- Where
- India
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Melasma, Hyperthyroidism
Comparative Study of mMASI Before and After Hyperthyroid Therapy in Hyperthyroid Subjects With Melasma
Study's objectives are to determine proportion of melasma cases in hyperthyroid patients and to compare severity of melasma before and after medications of three months hyperthyroid therapy using modified melasma area and…
- Trial name
- NCT04346901
- Testing
- Thiamazol
- Where
- Indonesia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)