Clinical trials: Melatonin Deficiency
Sleep Quality, DNA Damage Repair Deficiency
Melatonin and DNA Damage Study
This research aims to determine if melatonin supplementation, through improvements in sleep quality, increases the ability to repair oxidative DNA damage and reduce lipid peroxidation levels among nightshift workers.
- Conditions
- Sleep Quality, DNA Damage Repair Deficiency, Oxidative Stress
- Trial name
- NCT03945955
- Testing
- Melatonin
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Physical Exercise, Sleep Disturbance
Treatment of Sleep Disturbance in Children With ASD
This RCT study aims to compare effectiveness physical exercise and melatonin supplement on treating sleep disturbance in children with ASD.
- Conditions
- Physical Exercise, Sleep Disturbance, Autism Spectrum Disorder, Melatonin Deficiency
- Trial name
- NCT04878198
- Testing
- Jogging program, Melatonin supplement intervention
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- Education University of Hong Kong
Newborn Morbidity, Oxidative Stress
Antioxidant Effects of Melatonin in Preterm
Preterm infants are at risk of free radical mediated diseases from oxidative stress (OS) injury. Melatonin (MEL) is a powerful antioxidant and scavenger of free radicals.
- Conditions
- Newborn Morbidity, Oxidative Stress, Pre-Term, Melatonin Deficiency
- Trial name
- NCT04785183
- Testing
- Melatonin drops
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Oxytocin Deficiency, Hypopituitarism
Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study)
Oxytocin (OT) is a hypothalamic peptide that enters the peripheral circulation via the posterior pituitary gland. OT plays a key role in regulating appetite, psychopathology, prosocial behavior and sexual function.
- Conditions
- Oxytocin Deficiency, Hypopituitarism, Hypothalamic Obesity, Pituitary Dysfunction
- Trial name
- NCT05319301
- Testing
- Melatonin
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Sleep, Mood
Tryptophan Supplementation to Improve Night Shift Workers' Health
This randomized cross-over double-blinded trial aims to investigate the health effect of oral l-tryptophan supplementation on workers who rotate night shift work, and to examine the influences of different frequencies and timings…
- Conditions
- Sleep, Mood, Burnout, Melatonin Deficiency
- Trial name
- NCT04505800
- Testing
- Tryptophan supplement, Maltose
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Pregnancy Preterm
Melatonin Levels in Preterm and Term Newborn Infants
The general goal of the present study is to examine the developmental changes caused by melatonin in preterm and term newborns. The major brain lesions associated with cerebral palsy and cognitive impairment in preterm infants…
- Trial name
- MELIP (NCT01340417)
- Testing
- Measurements of melatonin levels in urine, blood, milk.
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Melatonin Deficiency
Melatonin Supplementation in Postmenopausal Women With H. Pylori-associated Dyspepsia
Background: The aim of the study was to assess the role of melatonin in chronic dyspepsia in this group of women, with consideration of Helicobacter infection.
- Trial name
- NCT04352062
- Testing
- Melatonin, Pantoprazole 40mg, Amoxicillin
- Where
- Poland
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz