Clinical trials: Membranous
Pulmonary Diffusing Capacity
Development of a New Method for Steady-State Measurement of NO Lung Diffusing Capacity in Healthy Subjects
Using a rapidly responding nitric oxide analyzer in a new developed modular lung-function-setup we are going to measure steady-state NO diffusing capacity in 107 healthy subjects (age 6-45 years).
- Trial name
- NCT00315965
- Testing
- Nitric oxide, Carbon monoxide, Helium
- Where
- Germany
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Epiretinal Membrane, Internal Limiting Membrane Wrinkling
Fovea ERM After Fovea-sparing ILM Peeling
To report cases who had received previous fovea-sparing internal limiting peeling membrane and developed secondary fovea epiretinal membrane contraction
- Trial name
- NCT04445142
- Testing
- fovea-sparing internal limiting membrane peeling
- Where
- Taiwan
- Volunteers
- 3 people
- Sponsor
- Changhua Christian Hospital
Labor Long, Nulliparity
HIDRATA Study: Efficacy of a Hydration Protocol in Nulliparous Women During Labor
Aim. To evaluate the efficacy of optimizing hydration during labor in nulliparous women with respect to reducing the duration of dilation and the second stage of labor, lowering the incidence of Cesarean sections and fever, and…
- Conditions
- Labor Long, Nulliparity, Premature Rupture of Membrane, Pregnancy, Prolonged
- Trial name
- HYDRATA (NCT03607929)
- Testing
- optimal, variability
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Videoscope, Maxillary Sinus
Videoscope-assisted Lateral Maxillary Sinus Floor Elevation: Evaluation of the Schneiderian Membrane for Micro-tears
This case series will recruit patients who require lateral maxillary sinus floor elevation surgery. This procedure will be carried out as per standard surgical protocol.
- Conditions
- Videoscope, Maxillary Sinus, Schneiderian Membrane
- Trial name
- NCT04510701
- Testing
- videoscope
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Acute Respiratory Distress Syndrome, Adult
Treatment of Severe Acute Respiratory Distress Syndrome With Allogeneic Bone Marrow-derived Mesenchymal Stromal Cells
This is a multi-center, open-label, non-randomized controlled trial. Patients with viral-induced acute respiratory distress syndrome (ARDS) on extracorporeal membrane oxygenation (ECMO) will be eligible.
- Trial name
- NCT02215811
- Testing
- Mesenchymal stromal cells
- Where
- 2 sites in Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska University Hospital
Peritonitis, Septic Shock
Effects of Hemoperfusion With a Polymyxin B Membrane in Peritonitis With Septic Shock
The purpose of this randomized, comparative, open and multi-centre study is to show that two sessions of hemoperfusion with Toraymyxin performed within maximum 36 hours after the surgery of a peritonitis by hollow organ…
- Trial name
- ABDO-MIX (NCT01222663)
- Testing
- standard therapy, hemoperfusion
- Where
- 18 sites in France
- Volunteers
- 243 people
- Sponsor
- Meditor SAS
ECMO
Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation
The goal of this multicenter, randomized trial is to compare early early left ventricular unloading by Intra-aortic Balloon Pump (IABP) versus conventional approach in patients with cardiogenic shock (CS) undergoing venoarterial…
- Trial name
- EASE-ECMO (NCT06872021)
- Testing
- Early IABP use, Conventional approach
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Beijing Anzhen Hospital
Diabetic Foot Ulcer (DFU), Ulcer Foot
Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs
The purpose of this study is to evaluate the efficacy of four dehydrated complete human placental membrane, also defined as Cellular, Acellular, Matrix-like Products/skin substitutes, plus SOC versus SOC alone in achieving…
- Conditions
- Diabetic Foot Ulcer (DFU), Ulcer Foot, Diabetic Foot, Foot Ulcer
- Trial name
- CAMPSTIM (NCT06449638)
- Testing
- Standard of Care, Revita, Relese
- Where
- 5 sites in United States
- Volunteers
- 272 people
- Sponsor
- StimLabs
Infertility, Male
Oral Astaxanthin and Semen Quality, Fertilization and Embryo Development in Assisted Reproduction Techniques Procedures
The purpose of the study is to determine whether administration of dietary supplement of astaxanthin with vitamin E improves the quality of sperm, fertilization and embryo development in Assisted Reproduction Techniques (ART)…
- Trial name
- Astax-ART (NCT02310087)
- Testing
- astaxanthin with vitamin E
- Where
- Slovenia
- Volunteers
- 80 people
- Sponsor
- University Medical Centre Ljubljana
Gingival Recession
Treatment of Gingival Recessions with Connective Tissue or Concentrated Growth Factor Membrane Using Tunnel Technique
This randomized controlled clinical study aimed to evaluate the success of the combination of tunnel technique and concentrated growth factor membrane for root coverage in treating multiple gingival recessions and compare with…
- Trial name
- NCT04561947
- Testing
- Tunnel technique, Connective tissue graft, Concentrated growth factor membrane
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bulent Ecevit University
Cardiogenic Shock
CARDSUP - SWISS Circulatory Support Registry
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing ECMO or Impella implantation at all included sites.
- Trial name
- CARDSUP (NCT04117230)
- Where
- 5 sites in Switzerland
- Volunteers
- 1,500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Trapeziometacarpal Osteoarthritis
Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of Trapeziometacarpal Osteoarthritis
The objective of this clinical trial is to evaluate whether a human umbilical cord amniotic membrane allograft can serve as an interposition implant in the surgical treatment of trapeziometacarpal osteoarthritis.
- Trial name
- NCT07435571
- Testing
- with SclerFIX
- Where
- 4 sites in France
- Volunteers
- 22 people
- Sponsor
- TBF Genie Tissulaire
Rupture of Membranes; Delayed Delivery (Following Spontaneous Rupture), Rupture of Membranes; Premature
Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA
This study is a non-blinded, prospective, randomized controlled trial designed to compare the effect of outpatient oral antibiotics (i.e., amoxicillin and azithromycin) on the length of time (days) that pregnancy continues after…
- Conditions
- Rupture of Membranes; Delayed Delivery (Following Spontaneous Rupture), Rupture of Membranes; Premature, Rupture of Membranes; Premature, Affecting Fetus, Preterm Birth
- Trial name
- NCT04047849
- Testing
- Antibiotics, oral Azithromycin and oral Amoxicillin
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Woman's
Cardiac Arrest, Cardiopulmonary Resuscitation
Cardiac Arrest Extra Corporeal Oxygenation Membrane
French guidelines for Cardio Pulmonary Resuscitation (CPR) consider Extra-Corporeal Life Support (ECLS) as one option in Refractory out-of hospital Cardiac Arrest (ROHCA) patients with a no-flow less than five minutes and absence…
- Conditions
- Cardiac Arrest, Cardiopulmonary Resuscitation, Advanced Cardiac Life Support, Extracorporeal Life Support
- Trial name
- CAREECMO (NCT03352999)
- Testing
- Fast track access to vaECMO
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
To Analyze and Compare the Efficacy and Safety of Ondansetron and Tablet for the Prevention of Moderate and Hypoemetic Chemotherapy
Comparative Study on the Efficacy and Safety of Ondansetron Oral Membrane for the Prevention of Vomiting During Moderate Hypoemetic Chemotherapy
Children aged 4-15 years scheduled to receive Moderate or low emetic chemotherapy were randomly assigned to arm-A (Ondansetron mouth soluble film) or arm-B (Ondansetron tablet).
- Trial name
- Ondansetron (NCT06371014)
- Testing
- Ondansetron oral membrane
- Volunteers
- 200 people
- Sponsor
- Shanghai Children's Medical Center
Preterm Premature Rupture of Membranes (PPROM), Premature Rupture of Membranes (PROM)
Effects of Emotional Freedom Technique and Music Therapy in High-Risk Pregnancy
Pregnancy is a physiological process; however, it is also a dynamic period during which obstetric and medical complications that may threaten maternal and fetal health can occur.
- Conditions
- Preterm Premature Rupture of Membranes (PPROM), Premature Rupture of Membranes (PROM), High-Risk Pregnancy
- Trial name
- NCT07559071
- Testing
- Emotional Freedom Technique (EFT), Music Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 177 people
- Sponsor
- Selcuk University
Extracorporeal Membrane Oxygenation Complication, Cerebral Circulatory Failure
Monitoring of Cerebral Blood Flow in Patients on Extracorporeal Membrane Oxygenation
Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a supportive therapy, indicated in case of severe, possibly reversible pulmonary failure, refractory to conventional therapies.
- Trial name
- NOTICE (NCT05303363)
- Testing
- VV-ECMO
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Flexor Tendon Injury
The Effect of Human Amniotic Membrane Allograft on Functional Recovery After Flexor Tendon Repair
The objective of this pilot study is to gain observational insight into potential preventive features of amniotic membrane transplantation in the adhesion formation after flexor tendon repair.
- Trial name
- NCT02361814
- Testing
- The use of amnionic membrane allograft
- Where
- Finland
- Volunteers
- 5 people
- Sponsor
- Tampere University
Atrophic Ridge
Guided Bone Regeneration Using Ti-Reinforced PTFE Membrane Vs. Khoury's Technique in Augmentation of Posterior Mandibular Defects
The aim of the present clinical trial is to compare two different alveolar ridge bone augmentation techniques for mandibular horizontal bone defects.
- Trial name
- NCT07394933
- Testing
- Khoury's bone shell technique, GBR using Ti-reinforced PTFE Membrane
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- British University In Egypt
Glaucoma, Blindness, Acquired
Implantable Intraocular Pressure Sensor for Glaucoma Monitoring in Patients With Boston Keratoprosthesis Type 1
The purpose of this study is to evaluate the safety and performance of the EYEMATE system in patients undergoing concomitant implantation of a BKPro type 1 and an EYEMATE sensor over the 24 months period beginning at implantation.
- Conditions
- Glaucoma, Blindness, Acquired, Keratitis, Herpetic, Ocular Cicatricial Pemphigoid
- Trial name
- BKPro (NCT03421548)
- Testing
- EyeMate
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
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