Clinical trials: Membranous
Tympanic Membrane Perforation
Tympanoseal (Tympanic Membrane Device) Clinical Study
The purpose of this investigational study is to assess the ability of Tympanoseal (sodium/calcium alginate), an investigational device, to act as a scaffold during healing of the tympanic membrane.
- Trial name
- NCT02918942
- Testing
- Tympanoseal
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Grace Medical, Inc.
Extracorporeal Membrane Oxygenation
Feasibility and Prognosis of Early Rehabilitation in Patients With ECMO
ECMO is increasingly used in critically ill patients with severe circulatory and/or respiratory failure. Because of the catheterization of the femoral artery and femoral vein, usage of sedatives, and occasionally with…
- Trial name
- NCT05083624
- Testing
- rehabilation therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- JinyanXing
Laparoscopic General, Gynecological and Urologic Surgeries
Evaluation of the Sevoflurane Consumption During General Anesthesia When Using the MemsorbTM Membrane
The study aims at determining whether replacing the classical chemical absorber Dräegersorb 800+ on Dräeger Perseus A500 machines (Dräeger, Lübeck, Germany) by the new membrane technology-based product (Memsorb™, DMF Medical…
- Trial name
- MEMSEV (NCT04539405)
- Testing
- To evaluate sevoflurane consumption when using Memsorb, To evaluate sevoflurane consumption when using classical Dräegersorb
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Gingival Recession
Evaluating Coronally Advanced Flap With Platelet-rich Fibrin Membrane and Chorion Membrane for Gingival Recession
The present study was a double-blind, randomised, controlled clinical trial with a parallel design, comparing the coronally advanced flap (CAF) with platelet-rich fibrin (PRF) and chorion membrane (CM) for the treatment of…
- Trial name
- NCT07308405
- Testing
- Coronally advanced flap (CAF) with platelet-rich fibrin (PRF), A similar surgical procedure was followed for the recipient bed preparation similar to that for the PRF membrane. A chorion membrane (Tissue bank, Tata Memorial Hospital, Mumbai, Maharashtra, India) o
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of Dental Sciences, Bareilly, Uttar Pradesh, India
ExtraCorporeal Membrane Oxygenation (ECMO), Wound Complications
Closed Incision NPWT to Prevent Wound Complications Post-ECMO
Patients undergoing extracorporeal membrane oxygenation (ECMO) are at increased risk of wound complications at the vascular access site after decannulation. These complications may delay recovery and increase healthcare burden.
- Conditions
- ExtraCorporeal Membrane Oxygenation (ECMO), Wound Complications, Surgical Site Infection (SSI)
- Trial name
- PREVENT-ECMO (NCT07709546)
- Testing
- Prophylactic Closed-Incision Negative Pressure Wound Therapy, Standard Wound Dressing
- Volunteers
- 144 people
- Sponsor
- St. Antonius Hospital
Osteoarthritis, Fibromyalgia
Efficacy & Safety Study of Natural Eggshell Membrane (NEM) for the Treatment of Joint & Connective Tissue Disorders
The purpose of this study was to evaluate the use of the dietary supplement Natural Eggshell Membrane (NEM) for the treatment of joint and connective tissue discomfort \& pain.
- Trial name
- NCT00750854
- Testing
- NEM Formulation X, NEM Formulation Y
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- ESM Technologies, LLC
Sickle Cell Disease, Cerebral Stroke
Cerebral Oxygen Metabolism in Children
The purpose of this research study is to better understand how blood flow and metabolism change can influence brain development in the early decades of life.
- Trial name
- COMIC (NCT04157179)
- Testing
- Carbon Dioxide
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Alveolar Bone Loss, Alveolar Bone Resorption
Tomographic and Histologic Assessment on the Influence of the Use of a Collagen Membrane to Protect the Antrostomy After Maxillary Sinus Floor Augmentation.
the aim of the present study was to evaluate the dimensional variation and osseointegration of mini-implants at augmented sinus with the antrostomy left unprotected or protected with a collagen membrane.
- Trial name
- NCT03899688
- Testing
- Maxillary sinus augmentation
- Where
- Colombia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Hyaline Membrane Disease, Preterm Infant
Evaluation of the Neonatal Autonomic Stress During Intubations Under Propofol in a Population of Premature Infants Under 33 w'GA
Hyaline membrane disease is one of the leading causes of morbidity and mortality in premature newborns in industrialized countries.
- Trial name
- PROPOSURF (NCT03721640)
- Testing
- electrocardiogram
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Prostate Cancer
Comparison of PET Imaging Patterns With PSMA and AR Expression in Prostate Cancer and Bladder Cancer
Patients suffering either from newly diagnosed very high risk locally advanced and/or oligometastatic prostate cancer (cohort A), metastatic castration-resistant prostate cancer (mCRPC, cohort B), newly diagnosed postate cancer…
- Trial name
- NCT05109884
- Testing
- PSMA PET Scan, FDHT PET Scan
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Vienna
Hypospadias, Hypospadias and Epispadias and Other Penile Anomalies
Efficacy of Amniotic Membranes in Complex Genitourinary Reconstruction
Urinary fistulas are unfortunately one of the most common post operative complications in hypospadias repairs and bladder neck transections on pediatric and adult populations, an estimated 20%, resulting in multiple repeat…
- Conditions
- Hypospadias, Hypospadias and Epispadias and Other Penile Anomalies, Fistula, Fistula, Urinary
- Trial name
- NCT03685955
- Testing
- Amniotic membranes
- Sponsor
- Johns Hopkins University
Fetal Growth Restriction (FGR), Preterm Birth
Enhancing Prediction of Adverse Pregnancy Outcomes in Africa Through Partnerships and Innovation
Pregnancy complications such as pre-eclampsia (high blood pressure during pregnancy), poor fetal growth, unexplained stillbirth, and spontaneous preterm birth are major causes of illness and death for mothers and babies in…
- Conditions
- Fetal Growth Restriction (FGR), Preterm Birth, Still Births, Abruptio Placentae
- Trial name
- EPAPOA (NCT07844876)
- Where
- 2 sites in Uganda
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Makerere University
Macular Degeneration, Age Related
Efficacy of Faricimab in Patients With Subretinal Hyper-reflective Material
Whose aim is to: Determine the percentage of patients with resolution of subretinal hyperreflective material (SHRM) at week 16. This study is intended to be performed in the ophthalmology departments or ophthalmology clinics of…
- Trial name
- NCT07403825
- Testing
- Vabysmo 6 MG in 0.05 ML Injection
- Where
- 10 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Biobizkaia Health Research Institute
Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome)
RECOMMEND Platform Trial
The goal of this platform trial is to determine the efficacy, safety and cost-effectiveness of various interventions in patients with acute cardiorespiratory failure requiring extracorporeal membrane oxygenation (ECMO) The main…
- Conditions
- Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome), Intensive Care Medicine, Cardiac Arrest (CA)
- Trial name
- RECOMMEND (NCT06526533)
- Testing
- Liberal RBC Transfusion, Restrictive RBC Transfusion
- Where
- 3 sites in Australia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Retinal Detachment
Internal Limiting Membrane Flaps for Coexistent Macular Hole and Retinal Detachment
Purpose: To evaluate the logical surgical approaches in closing macular holes in eyes of proliferative diabetic retinopathy with retinal detachment
- Trial name
- ILMFCMHRDPDR (NCT03618498)
- Testing
- ILM flaps insertion techniques or free ILM flaps.
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Changhua Christian Hospital
Out-of-Hospital Cardiac Arrest
Induced Hypothermia in Cardiac Arrest Patients Rescued by Extracorporeal Cardiopulmonary Resuscitation.
Background： Cardiopulmonary resuscitation (CPR) with closed-chest cardiac massage has been shown that survival to discharge rate is poor.
- Trial name
- NCT00965016
- Testing
- hypothermia
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Min-Sheng General Hospital
Tympanic Membrane Perforation
Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations
This study is a double blinded, placebo-controlled phase II study evaluating the efficacy of FGF-2 for the treatment of chronic non-healing tympanic membrane perforations (TMP).
- Trial name
- NCT04960384
- Testing
- FGF-2
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- NYU Langone Health
Infant, Premature, Diseases
Enteral Supplementation With Docosahexaenoic Acid and Arachidonic Acid (DHA-AA) in Preterm Infants
Docosahexaenoic acid (DHA) and arachidonic acid (AA) have a critical effect on the health and neuronal development of the fetus and newborn.
- Trial name
- NCT06366893
- Testing
- DHA/AA emulsion supplement for preterm infant
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Septic Shock, Extracorporeal Membrane Oxygenation Complication
Study on the Efficacy and Timing of ECMO Therapy in Children With Refractory Septic Shock
Severe sepsis and septic shock remain the leading causes of child mortality worldwide. Sepsis is a complex process that ultimately leads to circulation disorders, organ perfusion abnormalities, capillary leakage, tissue hypoxia…
- Trial name
- NCT03948048
- Testing
- ECMO
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Fudan University
Rupture of Amniotic Membranes
Analysis of ROM Plus to Detect Rupture of Membranes
Specific objectives include confirmation: i) that the ROM PLUS consistently and accurately diagnoses rupture of membranes (ROM), ii) that the technique can be understood and applied in clinical practice, and iii) that the ROM…
- Trial name
- NCT01366443
- Testing
- Sterile speculum exam, ROM Plus Exam, Chart Reveiw
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Clinical Innovations, LLC
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