Clinical trials: Membranous
Dry Eye
Dry Eye OmniLenz Application of Omnigen Research Study
Dry eye disease (DED) is a disease of the ocular surface characterised by ocular surface inflammation and damage and neurosensory abnormalities.
- Trial name
- DOORS (NCT04553432)
- Testing
- Amniotic membrane Omnigen[TM], Bandage soft Contact Lens OmniLenz[R]
- Where
- United Kingdom
- Volunteers
- 79 people
- Sponsor
- Aston University
Narrow Alveolar Ridge, CGF Concentrated Growth Factor
Clinical and Radiographic Evaluation of Ridge Splitting With Simultaneous Implant Placement Covered With Concentrated Growth Factor Membranes in Narrow Alveolar Ridge
This study aims to evaluate the tissue biotype and bone density around dental implants in patients with narrow alveolar ridge. Ridge splitting with simultaneous implant placement covered with concentrated growth factor (CGF)…
- Conditions
- Narrow Alveolar Ridge, CGF Concentrated Growth Factor, Postoperative Pain, Implant Placement
- Trial name
- CGF (NCT07534787)
- Testing
- Ridge splitting, Dental implant placement, Concentrated Growth Factor (CGF)
- Where
- 2 sites in Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Senile Cataract, Epiretinal Membrane
Clareon Intraocular Lens Stability in Vitrectomy Patients: CLOVE Study
This prospective randomized controlled trial will be conducted to investigate Clareon intraocular lens (IOL) stability in vitrectomy patients. The investigator plans to target the patients undergoing cataract surgery.
- Conditions
- Senile Cataract, Epiretinal Membrane, Vitreous Hemorrhage
- Trial name
- NCT06383754
- Testing
- Clareon, Tecnis 1
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Pneumonia, Bacterial, Extracorporeal Membrane Oxygenation
" Study of the Benefit of Nebulized Amikacin in the Treatment of Gram-negative Bacillus Pneumonia Acquired During Mechanical Ventilation in Patients Receiving Extracorporeal Membrane Veno-arterial Oxygenation "
Pneumonia are the most frequent infectious complication in patients on Extracorporeal Membrane Oxygenation Veno-arterial (ECMO-VA), with a treatment failure rate of around 40%, even though antibiotic therapy is tailored to the…
- Trial name
- NAVAP-ECMO (NCT06602557)
- Testing
- Amikacin, Standard of care
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Corneal Ulcers, Cataract
The Application of Fibrin Glue (Tissucol Duo Quick) in External Eye Surgeries
The fibrin sealants are prepared from fibrinogen, thrombin, and sometimes factor XIII that have been purified from human plasma. Tissucol Duo Quick (Baxter, Vienna, Austria) is a kind of fibrin sealants with popular use.
- Conditions
- Corneal Ulcers, Cataract, Pterygium, Retinal Detachment
- Trial name
- NCT02138019
- Testing
- Fibrin Glue assisted external eye surgery, Fibrin glue
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Macular Disease, Rhegmatogenous Retinal Detachment
Combined Vitrectomy and Femtosecond Laser-assisted Cataract Surgery
Based on the progress of cataract surgery, intraocular lens development, vitreoretinal surgery and anesthesia technology in recent years, the purpose of this study is to develop a new type of more accurate and minimally invasive…
- Conditions
- Macular Disease, Rhegmatogenous Retinal Detachment, Epiretinal Membrane, Cataract
- Trial name
- NCT05588037
- Testing
- FLACS +PPV+IOL + air, FLACS +PPV+IOL + epiretinal membrane peeling + Ozurdex, FLACS + PPV+IOL + internal limiting membrane peeling + air
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Myopic Choroidal Neovascular Membrane
Intravitreal Pegaptanib in Treatment of Choroidal Neovascularisation Secondary to Pathologic Myopia
Intravitreal pegaptanib for treatment of choroidal neovascularisation secondary to pathologic myopia
- Trial name
- INGECT (NCT01218230)
- Testing
- Intravitreal Pegaptanib
- Where
- India
- Sponsor
- L.V. Prasad Eye Institute
Preterm Labor
Uterocervical Angle in Patients With Preterm Premature Rupture of the Membranes
To evaluate the performance of uterocervical angle (UCA) in the prediction of labor timing in patients with preterm premature rupture of the membranes
- Trial name
- NCT04095507
- Testing
- uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nefise Nazlı YENIGUL
Premature Rupture of Membranes
FOLCROM Trial: Foley Catheter in Rupture of Membranes
Multicenter randomized clinical trial comparing oxytocin versus oxytocin and foley catheter for induction in women who present with premature rupture of membranes who are not in labor.
- Trial name
- FOLCROM (NCT01973036)
- Testing
- Foley Catheter, Oxytocin
- Where
- 5 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Ocular Cicatricial Pemphigoid
Clinical Trial Evaluating Rituximab in Ocular Cicatricial Pemphigoid
Cicatricial pemphigoid is an autoimmune blistering disease which affects the skin, mucous membranes, and, in a small subset of patients, the eye. Progressive ocular disease can lead to irreversible damage and blindness.
- Trial name
- NCT00584935
- Testing
- Rituximab
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Alabama at Birmingham
Hemodialysis, Coagulation
Dialysis Performance of Different Dialyzer Membranes Using Different Coagulation Strategies
Coagulation within the dialyzer membrane fibres is an obvious biological sign of bio-incompatibility. To avoid clotting during extracorporeal treatment, an anticoagulant is added to the circuit, resulting in an increased risk for…
- Trial name
- NCT03820401
- Testing
- choice of dialyzer, choice of dialysis mode, choice of anticoagulation strategy
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Ghent
Stage 2 or 3 Full Thickness Macular Hole
Full Thickness Macular Hole and Internal Limiting Membrane Peeling Study
A macular hole is a fairly common problem in the retina and is an important cause of loss of central vision. The aim of this study is to determine whether, in patients with a stage 2 or 3 full thickness macular hole (FTMH)…
- Trial name
- FILMS (NCT00286507)
- Testing
- Vitrectomy, post hyaloid detachment and gas injection with or without ILM peel.
- Where
- 9 sites in Ireland, United Kingdom
- Volunteers
- 141 people
- Sponsor
- University of Aberdeen
Epidermolysis Bullosa, Chronic Skin Ulcer
Uses of Irradiated Human Amniotic Membrane in the Treatment of Dystrophic Epidermolysis Bullosa Patients
To evaluate the effect of human amniotic membrane as a weekly dressing on chronic wounds in Epidermolysis Bullosa (EB) patients.
- Trial name
- NCT03942250
- Testing
- REGE pro dressing
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Egyptian Atomic Energy Authority
Optic Disc Structural Anomaly, Maculopathy
Surgical Management of Optic Disc Pit Maculaopathy
To evaluate the anatomical and functional results of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling, endolaser photocoagulation and gas tamponade in management of optic disc pit (ODP)…
- Trial name
- NCT03185936
- Testing
- pars plana vitrectomy with internal limiting membrane (ILM) peeling
- Volunteers
- 9 people
- Sponsor
- Minia University
Intraocular Implants, Extended Depth of Focus
Quality of Vision After Implantation of EDOF Implants Versus Monofocal Implants in Patients Who Underwent Epiretinal Membrane and Cataract Surgery
Phacoexistence, the first surgical procedure performed in France, naturally raises the question of lens replacement. In recent years, the choice of intraocular lenses has expanded considerably.
- Trial name
- MACAEDOF (NCT07789249)
- Testing
- Questionnaires, Intermediate visual acuity, Optical coherence tomography
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- Almaviva Sante
Apicomarginal Defects
TO DETERMINE THE EFFECT OF ALLOGRAFT AND iPRF WITH OR WITHOUT COLLAGEN MEMBRANE ON HEALING OF APICOMARGINAL DEFECTS
To determine the effect of allograft and iPRF with or without collagen membrane on healing of apicomarginal defects : A Randomized Controlled Trial
- Trial name
- NCT07048171
- Testing
- Endodontic Micro-Surgery
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Badly Broken Down Vital Teeth
Immediate Implant Placement With Deproteinized Bovine Bone vs Deproteinized Bovine Bone With HAM Gel
Statement of the problem: Immediate implant placement is faced with several problems. One of the most important is the jumping gap present after implant placement and whether it needs to be augmented or not.
- Trial name
- NCT06916026
- Testing
- Xenograft, Xenograft mixed with HAM gel.
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Idiopathic Membranous Nephropathy, Tacrolimus
Study on the Application of Hyperspectral Imaging Technique in the Treatment of IMN by TAC
We propose hyperspectral imaging analysis as a method to identify the efficacy of hormone-tacrolimus therapy for PMN, and to classify sensitive and insensitive patients treated with hormone-tacrolimus regimen.
- Conditions
- Idiopathic Membranous Nephropathy, Tacrolimus, Hyperspectral Imaging
- Trial name
- NCT05797038
- Testing
- Tacrolimus for the treatment of IMN
- Volunteers
- 40 people
- Sponsor
- Qianfoshan Hospital
Meningococcal Infections
Regulation of Mucosal Immune Response to Systemic MenB Vaccine
Meningitis or septicaemia (blood poisoning) caused by group B meningococcal infection (MenB) is an important cause of death and disability in the UK. Prevention through vaccination therefore remains a key public health priority.
- Trial name
- NCT00774384
- Testing
- NZ MenB OMV vaccine (NZ98/254)
- Where
- 2 sites in United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Septic Shock, Acute Kidney Injury
Safety and Efficacy of HA380 Hemoadsorption in Patients With Septic Shock
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Intensive care unit (ICU) mortality in patients with septic shock and acute kidney injury (AKI) requiring continuous…
- Trial name
- HEMOX-HDF (NCT04997421)
- Testing
- Combined HA380 hemoadsorption and continuous veno-venous hemodiafiltration (CVVHDF) with Oxiris®-AN69 membranes, Continuous veno-venous hemodiafiltration (CVVHDF) with Oxiris®-AN69 membranes
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Turku University Hospital
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