Clinical trials: Membranous
Respiratory Failure
Lung Transplantation in Respiratory Failure Patients
Survival after cadaveric lung transplantation in recipients depended on ventilation support prior to transplantation has been reported to have relative high surgical mortality and morbidity rate.
- Trial name
- NCT00854165
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Recurrent Pterygium
Recurrent Pterygium Surgery Using Mitomycin C With Limbal Conjunctival or Amniotic Membrane
To compare the outcomes of limbal conjunctival autograft (LCAG) versus amniotic membrane graft (AMG) when combined with intraoperative 0.02% mitomycin C (MMC) after pterygium removal in patients with recurrent pterygium.
- Trial name
- NCT01319721
- Testing
- MMC, LCAG, AMG
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Shiyou Zhou
Prostate Cancer
Imaging Study to Investigate the Safety and Diagnostic Performance of rhPSMA 7.3 (18F) in Newly Diagnosed Prostate Cancer.
A prospective, Phase 3, multi center, single-arm, imaging study investigating the safety and diagnostic performance of Radio-hybrid Prostate Specific Membrane Antigen (rhPSMA) 7.3 (18F) Positron Emission Tomography (PET) ligand…
- Trial name
- NCT04186819
- Testing
- rhPSMA-7.3 (18F) Injection, Positron Emission Tomography scan
- Where
- 34 sites in United States, Finland and 2 more
- Volunteers
- 356 people
- Sponsor
- Blue Earth Diagnostics
Cardiac Rhythm Disorder
Incidence and Morbidity of Cardiac Rhythm Disorders in Patients Assisted by ECMO-VA for Refractory Cardiogenic Shock
Brief Summary : Rhythm disorders are a frequent and potentially serious complication of critical patients in the ICU and postoperative cardiac surgery.
- Trial name
- CAVA-ECMO (NCT05788120)
- Testing
- Follow up by phone call
- Where
- 20 sites in France
- Volunteers
- 600 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Herpes Simplex Dendritic Keratitis
Evaluating Adjunctive Cryopreserved Amniotic Membrane Treatment in Herpes Simplex Dendritic Keratitis
To prospectively evaluate the effectiveness of Prokera Slim in adults with primary or recurrent herpetic epithelial keratitis in terms of visual function, corneal opacity, time to resolution, cost of care, number of patient…
- Trial name
- NCT04598282
- Testing
- Prokera Slim, Standard of Care
- Where
- United States
- Sponsor
- Oregon Health and Science University
Fetal Growth Restriction, Placenta
Placental Progesterone Membrane Receptors in Fetal Growth Restriction
This prospective observational case-control study aims to compare placental expression levels of progesterone membrane receptors, including PGRMC1, PGRMC2, and PAQR family receptors, among pregnancies affected by impaired fetal…
- Conditions
- Fetal Growth Restriction, Placenta, Progesterone Membrane Receptor, PGRMC1
- Trial name
- NCT07701837
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Samsun University
Acute Respiratory Distress Syndrome, Acute Respiratory Failure
Pronation During Veno-venous Extra Corporeal Membrane Oxygenation
The Acute Respiratory Distress Syndrome (ARDS) is defined by a recent (within 1 week) respiratory failure, not fully explained by cardiac failure or fluid overload.
- Trial name
- NCT05198986
- Testing
- Prone Position during Extra Corporeal Membrane Oxygenation (ECMO)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University Magna Graecia
Horizontal Alveolar Bone Defect, Guided Bone Regeneration
Guided Bone Regeneration in Lower Posterior Edentulous Arch Using Resorbable or Non Resorbable Membrane.
the purpose of this study is to compare the efficiency of non-resorbable membrane versus resorbable membrane in guided bone regeneration in atrophic posterior mandible.
- Trial name
- NCT07254494
- Testing
- guided bone regeneration using Resorbable membrane pericardium, guided bone regeneration using non resorbable ptfe membrane
- Where
- Lebanon
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Acute Respiratory Distress Syndrome, Septic Shock
Organ-substituting Technologies in the Treatment of Heart and Pulmonary Failure
The implementation of this project will improve the effectiveness of surgical treatment and reduce the level of complications and mortality among patients with heart failure and heart failure in the terminal stage.
- Conditions
- Acute Respiratory Distress Syndrome, Septic Shock, Sepsis
- Trial name
- OST (NCT05042622)
- Testing
- Cytokine adsorber filter, Extracorporeal hemoperfusion cartridge
- Where
- Kazakhstan
- Volunteers
- 90 people
- Sponsor
- National Research Center for Cardiac Surgery, Kazakhstan
Angioid Streaks of Macula
Antiangiogenic Therapy of CNV Associated With Angioid Streaks
The purpose of this study is to determine the effectiveness of antiangiogenic therapy to choroidal neovascularization secondary to angioid streaks.
- Trial name
- COAST_UAasCNV (NCT04119219)
- Testing
- Intravitreal injection
- Where
- 3 sites in Ukraine
- Volunteers
- 100 people
- Sponsor
- The Filatov Institute of Eye Diseases and Tissue Therapy
Extramembranous Glomerulopathy
In Vitro Immunomodulation in Membranous Nephropathy Relapses
In order to propose the best therapeutic option to relapsed MN patients with strong activation of the Th17 pathway, the investigators propose to study in vitro the effect of different immunomodulators on the Th17/Treg balance…
- Trial name
- BIOGEM (NCT05428605)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Edentulous; Alveolar Process, Atrophy
Titanium Mesh Versus Collagen Membrane for Closure of Window in Maxillary Sinus Elevation With Implant Placement
Evaluation the amount of bone height gained when using titanium mesh in closing the lateral window of the sinus compared to collagen membrane.Evaluation the quality of new bone gained when using of the titanium mesh to close the…
- Trial name
- NCT03401554
- Testing
- titanium mesh, collagen membrane
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fuchs Endothelial Corneal Dystrophy, FECD3
Study With QR-504a to Evaluate Safety, Tolerability & Corneal Endothelium Molecular Biomarker(s) in Subjects With FECD3
PQ-504a-001 (Fuchs Focus) is an open-label, single-dose, exploratory study to evaluate safety, tolerability, and corneal endothelium molecular biomarker(s) in subjects with Fuchs Endothelial Corneal Dystrophy with Trinucleotide…
- Conditions
- Fuchs Endothelial Corneal Dystrophy, FECD3, Corneal Diseases, LRS
- Trial name
- Fuchs Focus (NCT05052554)
- Testing
- QR-504a
- Where
- United Kingdom
- Sponsor
- ProQR Therapeutics
Medullary Thyroid Cancer, Medullary Thyroid Carcinoma
Evaluation of the 18F-PSMA Positron Emission Tomography (PET)/CT in Patients With Medullary Thyroid Cancer
Rationale: In patients with medullary thyroid cancer (MTC), molecular imaging is used to assess the extent of disease in the primary diagnostic process and follow-up period to determine possible therapeutic options.
- Conditions
- Medullary Thyroid Cancer, Medullary Thyroid Carcinoma, Thyroid Carcinoma, Medullary, Thyroid Cancer, Medullary
- Trial name
- MIMETIC (NCT05534594)
- Testing
- 18F-PSMA-1007
- Where
- Netherlands
- Volunteers
- 8 people
- Sponsor
- University Medical Center Groningen
Tooth Loss, Recession, Gingival
Use of Leucocyte- and Platelet-rich Fibrin Membranes in Single Implant
The objective of this randomized controlled clinical trial is to evaluate the increase of soft tissue thickness around single implants installed in maxillary esthetic area with the use of Leucocyte-Platelet rich Fibrin (L-PRF)…
- Trial name
- NCT03660566
- Testing
- Test - Implant with L-PRF, Control - Implant without L-PRF
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Critically Ill, Mechanically Ventilated, Extracorporeal Membrane Oxygenation Complication
Extracorporeal Membrane Oxygenation Physical Training
Critically ill patients who require extracorporeal membrane oxygenation (ECMO) are the sickest in the hospital. More patients are surviving but survivors have compromised functional recovery for months or years.
- Trial name
- ECMO-PT (NCT03328767)
- Testing
- Early activity and Mobilisation intervention
- Where
- 5 sites in Australia, Canada
- Volunteers
- 20 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Resolution of Pathologic Process
Reconstructive Management of Peri-implantitis
With the growing burden of peri-implantitis around the globe, interest has flourished on the management of this pathology. Nevertheless, lack of consensus exists in the pursuit of a predictable therapy.
- Trial name
- NCT05282667
- Testing
- Reconstructive therapy of peri-implantitis by means of bone graft (and barrier membrane in the test group)
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Preterm Premature Rupture of Fetal Membranes, Induction of Labor Affected Fetus / Newborn
A Randomized Trial of Induction Methods in Premature Rupture of Membranes
This study evaluates the addition of transcervical Foley catheter balloon and vaginal prostaglandin E2 induction in premature rupture of membranes.
- Trial name
- NCT03744078
- Testing
- Foley balloon catheter
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Dry Eye
Dry Eye OmniLenz Application of Omnigen Research Study
Dry eye disease (DED) is a disease of the ocular surface characterised by ocular surface inflammation and damage and neurosensory abnormalities.
- Trial name
- DOORS (NCT04553432)
- Testing
- Amniotic membrane Omnigen[TM], Bandage soft Contact Lens OmniLenz[R]
- Where
- United Kingdom
- Volunteers
- 79 people
- Sponsor
- Aston University
End Stage Renal Disease
Effect of Dialysis Dose and Membrane Flux in Maintenance Hemodialysis
OBJECTIVES: I. Evaluate whether hemodialysis providing a 2-pool, variable volume urea kinetic modelling value of 1.05 versus 1.45 reduces mortality and morbidity in patients with end stage renal disease. II.
- Trial name
- HEMO (NCT00004285)
- Testing
- Standard dose, low flux hemodialysis, Standard dose, high flux hemodialysis, High dose, low flux hemodialysis
- Where
- United States
- Volunteers
- 1,846 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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