Clinical trials: Membranous
External Hemorrhoid, External Hemorrhoid Thrombosed
Use of Human Dehydrated Amnion Chorion Allograft in Closed Hemorroidectomy
The purpose of this study is to determine the safety and effectiveness of human dehydrated amnion chorion allograft in closed hemorrhoidectomy as assessed by patient and wound assessments.
- Trial name
- NCT03479489
- Testing
- Human dehydrated amnion chorion allograft
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- MiMedx Group, Inc.
Membranous Nephropathy
Effect of B-cell Depleting Therapies on PLA2R-specific B Cells in Patients With Membranous Nephropathy
This is a non-pharmacological interventional monocentric study to primarily assess the levels of circulating phospholipase A2 receptor (PLA2R)-specific B cells in patients with PLA2R-mediated MN enrolled in the ORION and MONET…
- Trial name
- DEEPER (NCT06994468)
- Testing
- Flow-cytometry tetramer-based antigen-bait assay
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Chronic Periodontitis
Clinical, Anti-Inflammatory And Anti-Infective Properties Of Amniotic Membranes Used For Guided Tissue Regeneration
The objective of this study is to evaluate the anti-inflammatory and anti-infective properties of amniotic membrane (AM) when used for guided tissue regeneration (GTR) in periodontal bone defects.
- Trial name
- NCT02033226
- Testing
- Amniotic Membrane, Control group (Hydroxyapatite only)
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Bronchopulmonary Dysplasia (BPD)
Combined Oscillation-Volume guarantEe Study
Respiratory Distress Syndrome (RDS) remains the most common respiratory complication in the early postnatal period among preterm infants born before 32 weeks' gestational age.
- Trial name
- NCT07377955
- Testing
- HFOV, HFOV+VG
- Volunteers
- 348 people
- Sponsor
- Xingwang Zhu
Gastric Emptying, Delayed Gastric Emptying
Prevalence and Measurement of Delayed Gastric Emptying in Patients Receiving Extracorporeal Membrane Oxygenation
The goal of this observational study is to learn whether the stomach takes longer to empty in patients on the intensive care unit who are receiving ECMO (a machine that temporarily takes over the role of the lungs and heart)…
- Conditions
- Gastric Emptying, Delayed Gastric Emptying, Critical Illness, ExtraCorporeal Membrane Oxygenation (ECMO)
- Trial name
- PROPEL-ECMO (NCT07779174)
- Testing
- Gastric (stomach) ultrasound measurement, 'Residual volume' measurement, Scintigraphy (standard research method)
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Peritoneal Fibrosis
Epigenetic Determinants of Peritoneal Fibrosis
Peritoneal dialysis (PD) is a type of kidney replacement therapy for patients with chronic kidney disease where the peritoneal membrane is used to filter the blood.
- Trial name
- NCT02513615
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- McMaster University
Glaucoma
Safety and Effectiveness of PreserFlo and XEN Stents With or Without Amniotic Membrane in Glaucoma Surgery
Glaucoma is one of the leading causes of permanent blindness in the world. It happens when the optic nerve-the connection between the eye and the brain-is damaged. As this damage gets worse, vision is slowly lost.
- Trial name
- NCT07143708
- Testing
- Glaucoma Surgery with Amniotic Membrane, Glaucoma Surgery without Amniotic Membrane
- Volunteers
- 156 people
- Sponsor
- Nova Scotia Health Authority
Tooth Fractures, Tooth Extraction Status Nos
Alveolar Ridge Preservation Following Tooth Extraction.
Bone resorption after a tooth extraction is a generally accepted knowledge and has been demonstrated by many animal and human studies.
- Conditions
- Tooth Fractures, Tooth Extraction Status Nos, Caries
- Trial name
- NCT05505084
- Testing
- Tooth extraction and ridge preservation using different barrier mermbranes
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Prostate Cancer
Phase 1 of EC1169 In Patients With Recurrent MCRPC
The purpose of this study is to determine the safety of EC1169 and the best dose to use in humans in future studies. This study will also determine how EC1169 is distributed, broken down, passed and absorbed through your body and…
- Trial name
- NCT02202447
- Testing
- EC1169, EC0652
- Where
- 6 sites in United States
- Volunteers
- 40 people
- Sponsor
- Endocyte
Cardiovascular Diseases, Inflammation
Evaluation of Volume Status in Peritoneal Dialysis Patients
Patients with kidney failure on dialysis have a much higher risk of developing cardiovascular disease as compared to the general population.
- Conditions
- Cardiovascular Diseases, Inflammation, Peritoneal Dialysis
- Trial name
- NCT00182338
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- McMaster University
Glomerular Disease, Minimal Change Disease
KOrea Renal Biobank NEtwoRk System TOward NExt-generation Analysis
Glomerulonephritis (GN) generates an enormous individual and social economic burden. However, the therapeutic options are largely based on clinical and pathological parameters and the individual response to therapy or prognosis…
- Conditions
- Glomerular Disease, Minimal Change Disease, IgA Nephropathy, Membranous Nephropathy
- Trial name
- KORNERSTONE (NCT03929887)
- Testing
- Kidney Biopsy
- Where
- 6 sites in South Korea
- Volunteers
- 3,000 people
- Sponsor
- Seoul National University Hospital
PROM, Preterm (Pregnancy)
Novel Use of Central Venous Pressure (CVP) Set With McDonald Cerclage Technique for Amnioinfusion in Preterm Premature Rupture of Membranes Improves Amniotic Fluid Index and Neonatal Outcomes
This prospective, two-arm, non-randomized comparative interventional study evaluated the effectiveness of amnioinfusion using a central venous pressure (CVP) set compared with conventional transabdominal amnioinfusion in pregnant…
- Trial name
- CAM-PPROM (NCT07774832)
- Testing
- CVP-Set Amnioinfusion With McDonald Cerclage, Conventional transabdominal amnioinfusion
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Herlambang Herlambang
Pulp Disease, Dental
Evaluation of Different Materials in Pulpotomy of Primary Molars
The aim of the current study is to evaluate and compare clinical and radiographic success and antibacterial effect of Hyaluronic Acid and Amniotic membrane pulpotomy in primary molars in comparison with MTA pulpotomy (Randomized…
- Trial name
- NCT05981352
- Testing
- mineral trioxide aggregate pulpotomy, Dehydrated amniotic membrane pulpotomy, Hyaluronic acid pulpotomy
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Extracorporeal Membrane Oxygenation Complication
Use of Bivalirudin for Anticoagulation in Patients With Extracorporeal Membrane Oxygenation
The purpose of this study was to evaluate the efficacy and safety of bivalirudin in anticoagulation therapy in patients with extracorporeal membrane oxygenation (ECMO) compared with unfractionated heparin.
- Trial name
- NCT06275555
- Testing
- bivalirudin, unfractionated heparin
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Xiaotong Hou
Peri-Implantitis, Surgery
Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane
The objective of the present randomized clinical trial will be to compare two surgical methods of treating peri-implantitis. This study will determine if surgical debridement of peri-implantitis bone defects, including air powder…
- Trial name
- NCT05699343
- Testing
- InterOss Collagen (Bone xenograft) and InterOss Collagen Guide (Collagen membrane), InterOss Collagen (Bone xenograft)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Andrea Ravida
Resistant Vascular Ulcers
Evaluation of the Cryopreserved Amniotic Membranes in the Care of Resistant Vascular Ulcers
To evaluate tolerance and efficiency of cryopreserved amniotic membranes in local treatment of resistant vascular ulcers. To evaluate complete cicatrisation, efficiency on pain, prevention of infection, improvement of quality of…
- Trial name
- MAUV (NCT00820274)
- Testing
- amniotic membranes
- Where
- 3 sites in France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Limoges
Missing Maxillary Anterior Teeth
Poly Tetra Fluro Ethylene vs Native Collagen Membrane for Gbr in Anterior Maxilla
evaluation of amount of bone gained in the anterior maxilla using collagen membranes vs ptfe membrane while using a 1:1 mix of xenograft and autogenous bone
- Trial name
- NCT03839615
- Testing
- guided bone regenerations
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maternal Care for Other Abnormalities of Cervix
Maternal Consequences of Membrane Stripping
This study aims to investigate the maternal effects of membrane stripping during vaginal birth. This study was designed as an experimental case-control study.
- Trial name
- NCT06373250
- Testing
- Membrane stripping group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Idiopathic Membranous Nephropathy
Study on Single-nucleotide-polymorphism in Idiopathic Membranous Nephropathy
The purpose of this study is to analysis the different genotype in the idiopathic membranous nephropathy patients which with different therapeutic outcomes after treated by the Comprehensive Treatment Regimen or immunosuppressive…
- Trial name
- NCT01799460
- Testing
- The Comprehensive Treatment Regimen of Traditional Chinese Medicine, The immunosuppressive agents
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Maxillary Sinus
Effect of Buccal Fat Pad and Platelet Rich Fibrin After Ultrasonic Hydrodynamic Maxillary Sinus Membrane Elevation
Placing implants in the posterior maxillary area has the drawback of working with scarce, poor quality bone in a significant percentage of cases.
- Trial name
- NCT04123860
- Testing
- ultrasonic hydrodynamic maxillary sinus lift buccal pad fat, ultrasonic hydrodynamic maxillary sinus lift platelet rich fibrin
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
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