Clinical trials: Membranous
Multiple Myeloma
A Phase II Study of Bevacizumab and Bortezomib in Patients With Relapsed/Refractory Multiple Myeloma
The purpose of this study is to determine whether the combination of bevacizumab and bortezomib have increased efficacy in the treatment of relapsed/ refractory multiple myeloma.
- Trial name
- NCT00464178
- Testing
- Bortezomib
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
Inferior Turbinate Hypertrophy, Nasal Obstruction
Efficacy And Safety of An IRE System For Treatment of Inferior Turbinate Hypertrophy
The purpose of the IRE System is to address the clinical need for reducing the volume of hypertrophic inferior turbinate(s) causing nasal obstruction while minimizing side effects and complications.
- Conditions
- Inferior Turbinate Hypertrophy, Nasal Obstruction, Turbinate; Hypertrophy Mucous Membrane
- Trial name
- NCT06438185
- Testing
- IRE System
- Where
- 4 sites in Israel, Lithuania and 2 more
- Volunteers
- 48 people
- Sponsor
- ENTire Medical Ltd.
Cardiovascular Resuscitation, Venovenous Extracorporeal Membrane Oxygenation
Mechanical Cardiopulmonary Resuscitation During Treatment of Acute Respiratory Failure Through Extracorporeal Membrane Oxygenation.
In-hospital cardiovascular arrest is associated with poor outcome despite prompt treatment and optimal on-site resources. The population of patients treated by venovenous extracorporeal membrane oxygenation (vv-ECMO) due to…
- Trial name
- NCT05342363
- Where
- Germany
- Volunteers
- 117 people
- Sponsor
- Goethe University
Pediatric Traumatic Brain Injury
Overcoming Membrane Transporters to Improve CNS Drug Delivery - Improving Brain Antioxidants After Traumatic Brain Injury
The overall purpose of this research study is to investigate the safety of pharmacological therapies that may potentially improve pediatric outcomes after traumatic brain injury.
- Trial name
- Pro-NAC (NCT01322009)
- Testing
- Probenecid and N-acetyl cysteine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Pittsburgh
Peri-implantitis
20-25 Year Follow-Up on Regenerative Bone Procedures for Peri-Implantitis
The goal of this 20-25-year observational study is to investigate the outcomes of bone regenerative surgery in peri-implantitis.
- Trial name
- periimpl20y (NCT06648564)
- Testing
- Bone regenerative surgery with a bone graft substitute and a resorbable membrane
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Kristianstad University
Wounds, Trauma
Limb Salvage Through Tissue Engineering: A Novel Treatment Modality Using Dehydrated Human Amnion/Chorion Membrane
Extremity wounds with exposed critical structures, including bone and tendon are a major burden on the American healthcare system with limited treatment options.
- Conditions
- Wounds, Trauma, Injury, Limb Salvage
- Trial name
- NCT03521258
- Testing
- Dehydrated Human Amnion/Chorion Membrane, Flap-Based Reconstructive Surgery
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Tooth Extraction
Alveolar Ridge Preservation in Molar Extraction Sockets With an Open Healed Collagen Membrane: A Randomized Clinical Trial.
The resorption of alveolar ridge after tooth extraction develop difficulty in restoring the extraction area with implant or bridge.
- Trial name
- NCT04802148
- Testing
- membrane guided regeneration, collagen plug
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication
Quality of Life 1y and 2 y After VV-ECMO for COVID-19
This study aims to investigate the quality of life and the outcome after veno-venous extracoporeal membrane oxygenation (ECMO) support fir severe acute respiratory syndrome (ARDS) in COVID-19 patients.
- Conditions
- COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication, Quality of Life, Death
- Trial name
- NCT05780255
- Testing
- VV-ECMO
- Where
- Belgium
- Volunteers
- 28 people
- Sponsor
- University Hospital, Ghent
Metabolic Syndrome, Metabolic Endotoxemia
Alleviation Of Metabolic Endotoxemia In Adults With Metabolic Syndrome With Milk Fat Globule Membrane
Metabolic syndrome (MetS) adults (n = 24; 18-65 y) will be enrolled to complete a 2-arm, double-blind, randomized controlled, crossover trial.
- Trial name
- NCT03860584
- Testing
- MFGM-enriched full-fat dairy milk, Soy phospholipid/lecithin milk
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Oroantral Communication, Acute Oroantral Communication
Acute Oroantral Communication Closure: Resorbable Collagen Membrane vs. Buccal Advancement Flap Outcomes
Oroantral communication (OAC) is an abnormal opening between the oral cavity and the maxillary sinus that may occur after extraction of posterior maxillary teeth.
- Conditions
- Oroantral Communication, Acute Oroantral Communication, Oroantral Fistula, Post-extraction Maxillary Sinus Communication
- Trial name
- AOC (NCT07476664)
- Testing
- Resorbable collagen membrane OAC closure, Buccal advancement flap OAC closure
- Where
- Poland
- Volunteers
- 24 people
- Sponsor
- Medical University of Silesia
Chronic Otitis Media, Tympanic Membrane Perforation
A Prospective Comparative Study of Dry vs Wet Temporalis Fascia Graft in Tympanoplasty
This study was conducted to compare two methods of using temporalis fascia graft in tympanoplasty, namely wet temporalis fascia graft and dry temporalis fascia graft.
- Trial name
- NCT07595484
- Testing
- Wet Temporalis Fascia Graft Tympanoplasty, Dry Temporalis Fascia Graft Tympanoplasty
- Where
- Pakistan
- Volunteers
- 92 people
- Sponsor
- Shaikh Zayed Hospital, Lahore
Bone Gain
Customized Titanium Membrane for Growing Jaw Bone Horizontally
A single center, randomized, controlled, parallel-arm study is planned to investigate clinical outcomes of horizontal ridge augmentation with simultaneous single implant placement, using the newly designed Ti-membrane.
- Trial name
- NCT02227719
- Testing
- CTI, Collagen membrane
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
ARDS, COVID-19
ECMO for COVID-19 vs Influenza A H1N1 Associated ARDS
Objective: Veno-venous ECMO has been used as a rescue therapy for patients with severe ARDS associated to influenza A H1N1 and COVID19 viral pneumonia.
- Conditions
- ARDS, COVID-19, H1N1 Influenza
- Trial name
- InfluCOV_ECMO (NCT05080933)
- Where
- Italy
- Volunteers
- 308 people
- Sponsor
- University of Turin, Italy
Age-related Macular Degeneration
Changes in Retinal Function After Intravitreal Ranibizumab for Age-related Macular Degeneration
Age-related macular degeneration, a leading cause of blindness, is caused by an abnormal growth of the vessels beneath the retina.
- Trial name
- NCT00539734
- Testing
- ranibizumab
- Where
- Thailand
- Volunteers
- 25 people
- Sponsor
- Prince of Songkla University
Extracorporeal Membrane Oxygenation, Membrane Lung Function
Evaluation of Membrane Lung Function in High-altitude Regions
Over the last 20 years, extracorporeal membrane oxygenation (ECMO) has been used to support adult patients with respiratory or cardiac failure who are unlikely to survive conventional treatment methods.
- Conditions
- Extracorporeal Membrane Oxygenation, Membrane Lung Function, High Altitude
- Trial name
- NCT06152744
- Testing
- Monitoring membrane lung function at different altitudes
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Chao Yang Hospital
Extraction, Tooth, Tooth Fracture
Platelet-Rich Fibrin (PRF) vs Bone Graft With Membrane for Ridge Preservation After Tooth Extraction
This study uses a natural material called Platelet-Rich Fibrin (PRF) to help improve healing after tooth removal. PRF is made from your own blood.
- Conditions
- Extraction, Tooth, Tooth Fracture, Tooth Crown Fracture, Root; Fracture
- Trial name
- NCT07595198
- Testing
- Platelet-rich fibrin (PRF), Freeze-dried bone allograft, Collagen barrier membrane
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Ocular Graft Versus Host Disease
Evaluation of the Safety and Effectiveness of omniLenz in Patient With Ocular Graft vs Host Disease
A case series of patients presented with graft versus host disease with ocular involvement . The study recruited a total of 3 patients who were referred to cornea clinic of Farwaniya Hospital, Kuwait between April 2022 and April…
- Trial name
- NCT07066865
- Testing
- omniLenz
- Where
- Kuwait
- Volunteers
- 3 people
- Sponsor
- Farwaniya Hospital
Badly Broken Maxillary Premolars Indicated for Extraction
Soft Tissue Healing During Alveolar Ridge Preservation
Statement of the problem: Alveolar ridge preservation after tooth extractions is considered a challenge in oral surgery daily practice. Dental extraction is a traumatic procedure which leads to loss of alveolar bone.
- Trial name
- NCT06927453
- Testing
- Acrylic splint, No splint
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Advanced Lung Disease, Lung Transplant
Progressive Rehabilitation Therapy in Patients With Advanced Lung Disease
The International Society of Heart and Lung Transplantation Registry data shows that there is a growing population of critically ill patients with advanced lung disease undergoing lung transplantation.
- Conditions
- Advanced Lung Disease, Lung Transplant, Extracorporeal Membrane Oxygenation
- Trial name
- NCT03562728
- Testing
- MRP and NMES(neuromuscular electric stimulation), Standard of Care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Maryland, Baltimore
Periodontal Bone Loss
Platelet-rich Fibrin and Autogenous Bone vs Membrane and Autogenous Bone in Intrabony Defects
Currently, the most positive documented outcomes of periodontal regenerative therapy (PRT) in intrabony defects (IBDs) have been achieved with a combination of bone grafts ( BGs) and a regeneration material like membranes in…
- Trial name
- NCT04043754
- Testing
- Procedure/Surgery: Periodontal surgery with Membrane, Periodontal surgery with Platlet Rich fibrin
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
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