Clinical trials: Memory, Episodic
Memory Losses, Amnesia-Memory Loss
Effect of Affective Content on Drug Induced Amnesia of Episodic Memory
The purpose of this research is to understand how some of the drugs commonly used in anesthesia impair memory. We are particularly interested in whether the emotion associated with a memory influences how well these drugs are…
- Trial name
- NCT00142493
- Testing
- Propofol, Thiopental Sodium, Dexmedetomidine Hydrochloride
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cognitive Dysfunction, Memory Disorders in Old Age
Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment
The purpose of this study is to see if stimulation of the brain can improve memory. The investigators will use a device called transcranial magnetic stimulation that can stimulate and activate a specific part of the brain that is…
- Trial name
- NCT04558164
- Testing
- Active Theta Burst Stimulation
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, Los Angeles
Epilepsy, Unspecified, Pharmacologically Resistant, Memory Impairment
Episodic Memory Before and After Surgery in Drug-resistant Partial Epilepsies
This study has two purposes: firstly, a better understanding of the neurobiological processes underlying episodic memory and, secondly, the development of useful clinical applications for epileptic patients, in particular the…
- Trial name
- MemO-Epi (NCT01919957)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Epilepsy, Autobiographical Memory
Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings
The goal of this observational study is to develop novel methods for integrating multimodal data streams with invasive neural recordings to study autobiographical memory (AM) formation in individuals with implanted…
- Trial name
- CAPTURE (NCT06883981)
- Testing
- Free and Cued Recall Memory. Temporal Sequence and Spatial Memory
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Utah
Alzheimer Disease
Multiregional rtfMRI Neurofeedback for the Prevention of Alzheimer's Disease (NPAD)
This study aims to predict cognitive decline using a performance endophenotype of neuro-feedback based on functional magnetic resonance imaging in real time in a population at risk for Alzheimer's disease (AD).
- Trial name
- NPAD (NCT03173846)
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Schizophrenia
rTMS as a Probe of Episodic Memory Neurocircuitry in Schizophrenia
This will be a single site pilot study. 30 subjects with Early Phase Psychosis (EPP), defined as medical record documentation of the onset of clinically significant psychotic symptoms within the past ten years, will be enrolled.
- Trial name
- rTMS-EM (NCT04182113)
- Testing
- 1 Hz rTMS Stimulation
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Squamous Cell Carcinoma of the Head and Neck, Recurrent Head and Neck Squamous Cell Carcinoma
CIML NK Cell in Head & Neck Cancer
This research study is evaluating the safety and efficacy of a combination drug and biologic therapy in patients with advanced head and neck cancer.
- Trial name
- NCT04290546
- Testing
- Interleukin-15 Superagonist (N-803), CIML NK cell Infusion, Ipilimumab
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Dana-Farber Cancer Institute
Borderline Personality Disorder
Assessment of Sense of Identity in Patients Diagnosed With Borderline Personality Disorder. A Pilot Study
One of the key features and long considered a fundamental element of Borderline Personality Disorder is the disruption of identity.
- Trial name
- MASB (NCT04948905)
- Testing
- Evaluation using the Self-Defining Memory Questionnaire
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Epilepsy Intractable
Memory Retrieval and Encoding Investigated by Neural Stimulation
The purpose of this research is to understand biomarkers of human memory through correlational analyses and to use focal electrical stimulation as a causal manipulation to understand how biomarkers of memory relate to other brain…
- Trial name
- MEMREINS (NCT04286776)
- Testing
- Direct electrical stimulation
- Where
- 11 sites in United States
- Volunteers
- 800 people
- Sponsor
- University of Pennsylvania
Amnestic Mild Cognitive Impairment
CTA-MCI: Cognitive Control Training in Patients With Amnestic Mild Cognitive Impairment(CTA-MCI)
This study evaluates the efficacy and mechanism of internet-based cognitive control training on episodic memory function in patients with amnestic Mild Cognitive Impairment(aMCI).
- Trial name
- CTA-MCI (NCT03133052)
- Testing
- internet-based adaptive cognitive control training program
- Where
- China
- Volunteers
- 70 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Alcohol Use Disorder
Self-Concept and Autobiographical Memory in Alcohol Use Disorder
This study has two objectives. First, to evaluate the effectiveness of psychotherapy sessions based on self-concept and autobiographical memory in patients suffering from alcohol use disorders (AUD).
- Trial name
- CoSMA (NCT06985927)
- Testing
- psychotherapeutic sessions
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Post-Traumatic Stress Disorder
Therapeutic Effects of the Processing of Positive Memories Technique on Posttrauma Health
The current study will examine daily-level impacts of a technique addressing positive memory retrieval on thoughts, feelings, and health among individuals with trauma experiences.
- Trial name
- PPMT (NCT06680193)
- Testing
- Processing of Positive Memories Technique
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of North Texas, Denton, TX
Multiple Sclerosis, Relapsing-Remitting, Healthy Controls
The Relationships Between Personal Identity, Autobiographical Memory and Future Thinking in People With Multiple Sclerosis
Personal identity is composed of multiple facets of the self that are constructed and nourished through memories of past experiences (i.e., autobiographical memory) and the imagination of events that may occur in the future…
- Trial name
- SELFSEP (NCT05648292)
- Testing
- Neuropsychological tests and psychological questionnaires
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Aging
Modulation of Episodic Memory Using Theta Burst Stimulation (TBS)
The goal of this study is to evaluate the effect of white matter guided theta burst stimulation on episodic memory task performance in healthy older adults.
- Trial name
- NCT03406195
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Retrograde Amnesia
A Validation Study of the German Autobiographical Memory Interview
Electroconvulsive therapy (ECT) is recommended for the treatment of severe depression. But, despite the high remission rates the use of ECT is strongly limited by the social stigma and treatment-emergent cognitive side effects in…
- Trial name
- NCT04516863
- Testing
- German Autobiographical Memory Interview short-form
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rheinhessen-Fachklinik Alzey
Emotion Regulation, Mood Induction
Effectiveness of Personal Relevance of Visual Autobiographical Stimuli in Positive Emotions Induction
Background: The ability to retrieve specific memories is a cognitive and emotional protective factor. Among the most effective techniques to generate autobiographical memories is the use of audio-visual stimuli, particularly…
- Conditions
- Emotion Regulation, Mood Induction, Autobiographical Memory, Ageing
- Trial name
- NCT04251104
- Testing
- Images' personal relevance effectiveness in objective and subjective mood recovery
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Cannabis, Memory
Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 1
This study investigates the impact of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on recognition memory in healthy, regular cannabis users.
- Conditions
- Cannabis, Memory, Electroencephalography
- Trial name
- COBRA (NCT05868213)
- Testing
- Cannabis (smoked flower)
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Multiple Sclerosis
Influence of Emotional Disorders and Executive on the Components Retrograde and Anterograde Episodic Memory in MS
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system responsible for physical disability but can also cause cognitive disturbances annoying social and professional life of patients with the disease.
- Trial name
- ITEMS (NCT02518776)
- Testing
- Neuropsychological tests
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Generalized Anxiety, Fear of Failure
Optimization of Imagery Rescripting Research Using Generative Artificial Intelligence
This pilot randomized controlled trial will investigate the feasibility and effectiveness of using generative artificial intelligence to create personalized therapeutic scripts for imagery rescripting (ImRs).
- Conditions
- Generalized Anxiety, Fear of Failure, Rumination
- Trial name
- FRBN (NCT07189715)
- Testing
- Imagery Rescripting Intervention (AI-Generated)
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Episodic Memory, Healthy
Causal Role of Brain Networks in Episodic Memory
The goal of this study is to understand the basic brain mechanisms supporting episodic memory in healthy young adults. Transcranial magnetic stimulation will be used to influence brain activity in regions thought to be important…
- Trial name
- NCT05374551
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Boston College