Clinical trials: Memory Deficits
Impact of Pomegranate Juice on Memory in Older Adults
Study of Pomegranate Juice on Memory in Older Adults
This project is designed to study whether pomegranate juice benefits cognitive abilities in middle-aged and older non-demented volunteers.
- Trial name
- NCT02093130
- Testing
- Pomegranate Juice
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Schizophrenia, Attention Deficit Disorder With Hyperactivity (ADHD)
Investigating Mediodorsal Thalamus Representations Underlying Human Cognitive Flexibility
The goal of this basic experimental research study is to examine how the human thalamus supports flexible thinking and behavior.
- Trial name
- NCT07217652
- Testing
- High-resolution fMRI during working memory, cognitive control, and decision-making tasks
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kai Hwang
Alzheimer Dementia, Alzheimer Disease
SAD Phase I Study (First-in-human) to Investigate Contraloid Acetate
This is a single-center first-in-human single-ascending-dose clinical trial assessing the safety and tolerability of oral dosing of Contraloid acetate in healthy volunteers.
- Trial name
- NCT03944460
- Testing
- Contraloid
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Dieter Willbold
Aphasia, Acquired, Short-Term Memory Impairment
Short-term Memory Assessment in Patients With Poststroke Aphasia
Background and aim There is a growing awareness that people with aphasia (language problems) after a stroke often have difficulties with their short-term memory (STM).
- Trial name
- NCT06068296
- Testing
- short term memory assessment, Oxford cognitive screen, Token Test
- Where
- 2 sites in Belgium
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Delirium, Postoperative Cognitive Dysfunction
Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial
The purpose of this study is to determine whether preoperative administration of Rivastigmine prevents the incidence of postoperative delirium in patients undergoing major surgery as well as postoperative cognitive dysfunction.
- Trial name
- NCT00835159
- Testing
- Rivastigmine Patch
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Memory Impairment
The Effect of tES on a Cognitive Training
The aim of this study is to investigate the effect of a transcranial electrical stimulation (tES) on a cognitive training in healthy elderly and memory impaired participants.
- Trial name
- NCT03475446
- Testing
- real anodal tDCS healthy elderly, real tACS healthy elderly, real anodal tDCS MCI
- Where
- Switzerland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Bern
Age-Related Memory Disorders
A Study to Evaluate The Effects Of a Multivitamin/Mineral With Ginko In Subjects With Age Associated Memory Impairment
A Study to evaluate the cognitive effects and tolerance of a Multi-Vitamin/Mineral Preperation containing Gingko in elderly subjects with age associated memory impairment.
- Trial name
- NCT01160692
- Testing
- Multivitamin/Multimineral/Ginkgo (BAY 81-2775)
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Bayer
Mild Cognitive Impairment, Alzheimer Disease
A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses
The goal of this clinical trial is to test 6 months of aerobic exercise in older adults who are 65 years or older and have mild cognitive impairment (MCI) or probable/possible mild Alzheimer's Disease.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Cognitive Impairment, Cognitive Decline
- Trial name
- SMART (NCT05877196)
- Testing
- Moderate Intensity Continuous Training (MICT), Chair-based Stretch, High-Intensity Interval Training (HIIT)
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cognitive Function, Mood
The Effects of Efalex Active 50+ on Cognitive Performance, Well-being and Cerebral Hemodynamics in Healthy Older Adults
Dietary intake of omega-3 polyunsaturated fatty acids (n-3 PUFAs) is inversely associated with cognitive decline and dementia (e.g. Kalmijn et al. 2004, Heude et al. 2003, Morris et al. 2005, Dullemeijer et al. 2009).
- Conditions
- Cognitive Function, Mood, Well-being, Cerebral Blood Flow
- Trial name
- NCT01185379
- Testing
- Efalex active 50+, DHA rich fish oil
- Where
- United Kingdom
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Attention-deficit/Hyperactivity Disorder
A Genome-wide Association Study on the Endophenotype of Spatial Working Memory in ADHD
Specific Aims: 1. To find the genetic variations associated with spatial working memory performance in patients with ADHD by using genome-wide association studies (GWAS); 2.
- Trial name
- NCT02710929
- Where
- Taiwan
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Memory Impairment
Age-related Longitudinal Changes in Aviator Performance
Our overall goal has been twofold: 1) to evaluate whether there are significant age-related changes in flight simulator performance near age 60, and 2) to assess whether there is an alternative model that can explain longitudinal…
- Trial name
- NCT01364753
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Stanford University
Schizophrenia
Schizophrenia Sensory Gating Deficit With Quetiapine
The purpose of this study is the use of magnetoencephalography or MEG (a machine that measures magnetic activity in your brain) and electroencephalography or EEG (a technique that measures electrical activity in your brain) to…
- Trial name
- NCT00536783
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- New Mexico VA Healthcare System
Healthy
Cognitive Effects of Citicoline in Men and Women With Age-Associated Memory Impairment
The objective of this trial is to determine the effects of citicoline on cognitive performance in healthy Men and Women with Age-Associated Memory Impairment compared to a placebo.
- Trial name
- NCT03369925
- Testing
- Citicoline supplement
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kyowa Hakko Bio Co., Ltd.
Attention Deficit Disorder With Hyperactivity
Sleep and Memory Consolidation in Adults With Attention Deficit Hyperactivity.
Attention Deficit Disorder With Hyperactivity is associated with deficits in cognition and sleep. In healthy adults, memory consolidation processes are related to sleep spindle activity in the sleep electroencephalogram.
- Trial name
- HYPNOS (NCT05876286)
- Testing
- Neurological examinations
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Lack of Satiety, Dietary Modification
Breakfast Consumption in Preschoolers: Satiety, Diet Quality and Memory
One important factor determining school performance is the consumption of breakfast. While research has shown that older children perform better in school after consuming breakfast, there are little data for preschool-age…
- Conditions
- Lack of Satiety, Dietary Modification, Memory Deficits, Obesity
- Trial name
- NCT02122224
- Testing
- High fiber breakfast, High Protein Breakfast, High Protein/High Fiber Breakfast
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Purdue University
Age-Related Memory Disorders
A Safety and Efficacy Study of Ispronicline (TC-1734-112) in Subjects With Age Associated Memory Impairment (AAMI)
The purpose of this Phase II study is to evaluate the efficacy and safety of ispronicline (TC-1734-112) compared to placebo (inactive substance pill) in patients with age associated memory impairment (AAMI).
- Trial name
- NCT00109564
- Testing
- ispronicline (nicotinic acetylcholine receptor agonist)
- Where
- 15 sites in United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Targacept Inc.
ADHD, Time Perception Altered
Working Memory and Social-emotional Training for Preschoolers at Risk of ADHD
The study aims to explore the effectiveness of working memory training and social emotional training for young children with ADHD in Hong Kong.
- Conditions
- ADHD, Time Perception Altered, Working Memory, Social Skills
- Trial name
- NCT05162729
- Testing
- Game-like online working memory training, Game-like online social emotional training
- Where
- Hong Kong
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Healthy, Mild Cognitive Impairment
tES Effects on Associative Memory Performance
Previous studies showed that transcranial electric stimulation (tES) applied over the prefrontal cortex improves cognitive performance in healthy elderly adults as well as in patients suffering from mild cognitive impairment or…
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03351452
- Testing
- real anodal transcranial direct current stimulation, real transcranial alternating current stimulation
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Bern
Schizophrenia, Sensory Gating
Remediation of Schizophrenia Sensory Gating Deficit With Aripiprazole
The purpose of this study is the use of magnetoencephalography or MEG (a machine that measures magnetic activity in your brain) and electroencephalography or EEG (a technique that measures electrical activity in your brain) to…
- Trial name
- NCT00567099
- Testing
- Aripiprzole
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- New Mexico VA Healthcare System
Amnesia, Alzheimer Disease
OCT-Angiography and Adaptive Optics in Patients With Memory Impairment
Studies suggest an association between retinal abnormalities and NCD (Neuro Cognitive Disorders) whether they are linked to proven or prodromal Alzheimer's disease (aMCI : amnestic mild cognitive impairment), or to other…
- Conditions
- Amnesia, Alzheimer Disease, Lewy Body Disease, Parkinsons Disease With Dementia
- Trial name
- OCTAVO (NCT04389437)
- Testing
- Ophthalmological exam, Blood pressure measurement
- Where
- France
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild