Clinical trials: Memory Disorders
Alzheimer Disease, Memory Disorders
Virtual Reality Cognitive Stimulation for Alzheimer's
This study aims to evaluate whether immersive virtual reality (VR) can improve cognitive function and memory in patients with Alzheimer's disease.
- Trial name
- CODDI (NCT07645638)
- Testing
- Virtual reality
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidad de Burgos
HIV Infections
Immunologic Memory (Supp. of ATN 024)
This is an exploratory, laboratory-based evaluation of cellular immune response to immunization with hepatitis B surface antigen in HIV-infected and HIV-uninfected adolescents. This is a substudy of ATN 024 and ATN 025.
- Trial name
- NCT00142753
- Testing
- Engerix B, Twinrix for ATN 024, Recombivax
- Where
- 4 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Memory Disorders
AIT-082 Phase 1B Study
AIT-082 is a novel small molecule that crosses the blood-brain barrier to enhance nerve function by increasing levels of neurotrophic growth factors and encouraging nerve sprouting in the brain.
- Trial name
- NCT00000180
- Testing
- AIT-082
- Where
- 4 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Schizophrenia
Pilot Study Using an NMDA Antagonist to Modulate Transcranial Direct Current Stimulation (tDCS) Effects on Sensory Discrimination
Transcranial direct current stimulation (tDCS) is a non-invasive form of brain stimulation which uses a very weak constant current to temporarily excite the brain area of interest via small electrodes placed on the scalp.
- Trial name
- NCT02426983
- Testing
- Direct Current Stimulation, Dextromethorphan
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Aging Well, Memory Loss
Age Stereotype Priming and Social Participation
Memory performance is shown to be affected by age stereotypes among older adults. The purpose of the study is to examine the effects of age stereotype primes on episodic memory using priming intervention.
- Trial name
- ASPSP (NCT04202120)
- Testing
- Age-related stereotyping priming, Non age-related stereotype priming
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cognitive Impairment
Phenytoin for Memory Impairment Secondary to Megestrol
This study is designed to test if megestrol acetate induces changes in declarative memory in healthy controls and if pre-administration of phenytoin can ameliorate any induced cognitive impairments.
- Trial name
- NCT02595723
- Testing
- Phenytoin 200 mg capsule, Megestrol 800 mg liquid
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Dementia
Circadian Rhythm and Other Factors in Memory Clinic Patients
The CIRCAME study is a bicentric study of patients from 2 memory clinics in Paris. The main objective is to identify circadian rhythm components and other individual risk factors (sociodemographic, behavioral, and health related…
- Trial name
- CIRCAME (NCT05977712)
- Testing
- Questionnaire, Clinical examination, Accelerometer port
- Where
- 2 sites in France
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mild Cognitive Impairment, Memory Loss
Targeted Transcranial Magnetic Stimulation to Improve Hippocampal-dependent Declarative Memory Abilities
This is a pilot study of non-invasive transcranial magnetic stimulation (TMS) to improve memory in healthy adults. It will also examine treating memory deficits in older adults with amnestic mild cognitive impairment (aMCI), a…
- Trial name
- NCT03574207
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Acellular Pertussis, Tetanus
Multicentre Booster & Immune Memory Study of a Booster Dose of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine or a Single Dose of 23-valent Plain Polysaccharide Vaccine in Healthy Children Aged 11-18 Mths, Previously Vaccinated in Study 103488
Booster and immune memory study
- Conditions
- Acellular Pertussis, Tetanus, Hepatitis B, Diphtheria
- Trial name
- NCT00307567
- Testing
- Pneumococcal (vaccine)
- Where
- 51 sites in Germany
- Volunteers
- 689 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Blindness
Enhanced Tactile Memory in the Blind
This study will determine if the brain regions in blind people that would normally be involved in vision are used instead to remember touch.
- Trial name
- NCT00076700
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Mild Cognitive Impairment, Alzheimer's Disease
Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)
Memory deficits are common after traumatic brain injuries (TBI) and are characteristic of various forms of dementia, such as Alzheimer's disease and its common precursor mild cognitive impairment (MCI).
- Conditions
- Mild Cognitive Impairment, Alzheimer's Disease, Traumatic Brain Injury
- Trial name
- NCT00714571
- Testing
- Mnemonic strategy training (MST), Repeated exposure (XP), Subtracting Cues training
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Phobias, Claustrophobia
Effects of Low-Level Laser Stimulation With and Without Fear Extinction Training
There are two specific aims for this study. Aim 1 is to test whether low-level laser therapy (LLLT) can enhance the efficacy of fear extinction training in the modification of pathological fear.
- Conditions
- Phobias, Claustrophobia, Social Phobia
- Trial name
- NCT02926352
- Testing
- Extinction Training, Low-Level Laser Therapy
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Dementia With Lewy Bodies, Alzheimer Disease
Self and Autobiographical Memory in Dementia With Lewy Bodies and Alzheimer Disease: a Behavioral and Multimodal Neuroimaging Study
The present project aims at exploring different components of Self-consciousness or 'the Self', such as autobiographical memory, self-concept and subjective sense of Self, in dementia with Lewy Bodies (DLB) compared to…
- Conditions
- Dementia With Lewy Bodies, Alzheimer Disease, Self, Autobiographical Memory
- Trial name
- SELF-MCL (NCT04616287)
- Testing
- Neuropsychological assessment and Multimodal brain MRI
- Where
- France
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Chronic Lymphocytic Leukemia (CLL)
The Duration of Humoral Immunity and the Memory Cell Function After Vaccination With 7-valent Pneumococcal Conjugate Vaccine in CLL
Patients with chronic lymphocytic leukemia (CLL)have had very poor humoral responses to pneumococcal polysaccharide vaccine (PPV).
- Trial name
- KLL2 (NCT00919321)
- Testing
- Pneumococcal polysaccharide vaccine (PPV)
- Where
- Finland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Parkinson Disease, Aging
Role of Sleep on Motor Learning in Parkinson's Disease and Healthy Older Adults
People with Parkinson's disease (pwPD) often present difficulty consolidating newly learned skills into long-term memory. Sleep facilitates motor memory consolidation in healthy adults, especially in combination with targeted…
- Trial name
- TARGET-SLEEP (NCT04144283)
- Testing
- NAP, WAKE
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Volunteers, Flu Vaccine
Impact of FLU Vaccination on Nasal Resident Memory Immune Responses and Peripheral Respiratory-tropic Memory Immune Responses
Mucosal sites, such as respiratory mucosa, are the primary entry points entry points for pathogens. However, clinical evaluation of vaccines against respiratory respiratory pathogens is currently based primarily on analysis of…
- Trial name
- MUCOVAC_2 (NCT06824779)
- Testing
- Flu Vaccine, Biological samples
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cognition, Mood
Genistein, Equol, Cognitive Function and Mood: Twelve-week. (GECFAMc)
Isoflavones (ISF) are naturally occurring compounds that can provide protective benefits for certain domains of cognitive function.
- Trial name
- GECFAMc (NCT07742501)
- Testing
- Equol, Genistein, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Reading
Opioid Use Disorder
Autobiographical Memory in Opioid Use Disorder
The research study is being conducted to better understand memory function in people with opioid use disorder (OUD) and whether memory training can improve the symptoms and lives of people with OUD.
- Trial name
- NAMO (NCT06643988)
- Testing
- MemFlex
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cerebrovascular Accident, Aphasia
Dopaminergic Enhancement of Learning and Memory in Aphasia
The purpose of this study is to determine whether levodopa, in combination with a high frequency language training, is effective in boosting naming performance in patients with aphasia.
- Trial name
- NCT00102869
- Testing
- levodopa
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster