Clinical trials: Memory Functions
Healthy Volunteers
Pomegranate Extract and Memory
This project is designed to study whether pomegranate extract benefits cognitive abilities in middle-aged and older non-demented volunteers.
- Trial name
- NCT01950221
- Testing
- POMx
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Breast Cancer, Healthy
Impact of Cancer on Memory Functioning: Understanding Disorders Using Approaches in Neuropsychology and Neuroimaging
The purpose of this study is to investigate memory problems in patients with cancer.
- Trial name
- CANMEM (NCT01332916)
- Testing
- cognitive tests and cerebral IRM
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
Memory Functions
Influence of Salbutamol on Emotional and Cognitive Functions in Healthy Subjects
Aim is to investigate the effect of beta2 adrenergic stimulant salbutamol on emotional and cognitive functions in healthy humans.
- Trial name
- Salmon-Basel (NCT01957293)
- Testing
- Salbutamol
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Aging, Noninvasive Brain Stimulation
Memory Enhancement in Aging With Optimal Dosing
This project optimizes high-resolution transcranial Alternating Current Stimulation (tACS) to improve memory in healthy older adults, advancing drug-free approaches for Alzheimer's disease and related dementia (ADRD).
- Conditions
- Aging, Noninvasive Brain Stimulation, Memory
- Trial name
- NCT07461584
- Testing
- 1-day patterned tACS, 3-day patterned tACS, 5-day patterned tACS
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Sleep Quality, Cognitive Function
Effects of Walking Exercise on Sleep Quality in Older Adults
This study aims to explore whether increasing physical activity can improve sleep quality in older adults, particularly those with poor sleep, and whether such improvements positively influence cognitive functions such as memory…
- Trial name
- NCT07027176
- Testing
- walking exercise
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yea-Ru Yang
Memory Disorders in Old Age
Improving Working Memory in Older Adults
The research program will evaluate the theoretical claim that age-related memory and cognitive decline in humans result from the inefficient orchestration of rhythmic activity within large-scale cortical networks.
- Trial name
- NCT04362696
- Testing
- High definition transcranial electrical current stimulation
- Where
- United States
- Volunteers
- 964 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Rehabilitation, Working Memory
The Neural Substrates for Working Memory Training
This study aims to conduct a contrast study on the characteristics of functional and structural connectivity of neural networks of working memory in patients with acquired brain injury versus normal controls, using resting-state…
- Trial name
- WMT (NCT03012269)
- Testing
- Working memory training
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- China Rehabilitation Research Center
Mild Cognitive Impairment, Metabolic Syndrome
Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation
The study explores whether selective memory complaints (SMC), mild cognitive impairment (MCI) and the comorbidity of Metabolic Syndrome symptomatic of peripheral and cerebral hypo-metabolism with corresponding epigenetic shifts…
- Trial name
- NCT03319173
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Bristlecone Health, Inc.
Alzheimer Disease, Dementia
Exploratory Clinical Study and Validation of Blood Biomarkers for Alzheimer's Disease
This is a 24-month, monocentric, exploratory and observational clinical study aimed at developing and validating a blood-based diagnostic test for Alzheimer's disease (AD).
- Conditions
- Alzheimer Disease, Dementia, Neurodegenerative Disorders, Cognitive Decline
- Trial name
- ADKIT (NCT07294586)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Amoneta Diagnostics SAS
Language Development Disorders
Memorisation of Phonologic Information Among Children With Oral Language Developement Disorder
The disorder of oral language development is defined by the delay in language acquisition in children who possess efficient auditory acuity and normal non verbal intellect.
- Trial name
- MEMENTO (NCT02609542)
- Testing
- Eye Tracking
- Where
- France
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Healthy
Behavioral and Physiological Effects of Visual Training
The primary objective of this study is to evaluate the learnability of a 3 week, 40 minutes per day, 5 day per week, computer-based visual training exercise by healthy mature individuals undergoing normal aging.
- Trial name
- NCT00526942
- Testing
- SAAGE-designed, visual memory-based cognitive training
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Posit Science Corporation
Elderly
Acute Effects of Aerobic Exercise on Motor Memory Consolidation in Older People
Scientific evidence suggests that an aerobic exercise session promotes improvements in the consolidation of motor memory in adults.
- Trial name
- NCT03506490
- Testing
- Aerobic exercises
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Castelo Branco
Chronic Posttraumatic Stress Disorder
Enhancing Exposure Therapy for Post-traumatic Stress Disorder
This study is investigating a new brief psychotherapy for post-traumatic stress disorder (PTSD) which, modifies an already proven psychotherapy for PTSD by adding two new components and modifying several others.
- Trial name
- NCT01574118
- Testing
- Revisiting the Trauma memories, Processing the trauma memories, Psychoeducation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Obesity, Adolescent
Increased Protein at Breakfast for Weight Management in Overweight Adolescents
Adolescent obesity, negatively affecting the lives of over 18 million (34%) US adolescents, continues to be a major public health concern due to the increased risk of developing chronic diseases, including type 2 diabetes.
- Trial name
- NCT03146442
- Testing
- Breakfast
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Behavior
The Effects of Mindfulness Meditation on Brain Metabolism in the Limbic Regions Studied by Magnetic Resonance Spectroscopy
Stress reduction methods based on mindfulness meditation have been experiencing significant growth in various fields of society over the past twenty years.
- Trial name
- MEMOREM (NCT05710250)
- Testing
- 6-week MBSR program, 6-week muscular relaxation program
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Cognitive Decline
The Impact of Exercise on Hippocampus-dependent Cognition and the Gut Microbiota
The NeuroFit study will be investigating the impact of exercise on global cognition, hippocampus-dependent memory function and the gut microbiota in a middle-aged population.
- Trial name
- NeuroFit (NCT05397990)
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy Ageing
Effect of Polyphenol-rich Cocoa Products on Cognitive Function
This project aims to investigate whether consumption of cocoa polyphenols has an impact on cognitive function in individuals aged 50 to 60 years of age and if such an improvement is a result of an improvement in risk factors…
- Trial name
- NCT02996578
- Testing
- polyphenol rich chocolate bar, polyphenol rich cocoa powder, low polyphenol content chocolate bar
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Subjective Cognitive Decline
Effects of Individualized Theta-tACS on a Working Memory Training at SCD
The aim of the study is to investigate the effects and mechanisms of action of an individualized transcranial alternating current stimulation in the theta-range (ITF-tACS) on a three day spatial working memory training in healthy…
- Trial name
- tACOSenior (NCT06501755)
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
To Assess the Safety and Tolerability of Intranasal Administration of a Male Donor Memory T Lymphocyte Solution
A Phase I, Single-Center, Open-Label, Dose-Escalation Clinical Trial to Assess the Safety and Tolerability of an Intranasal Memory T Lymphocytes Solution in Adult Females: vRELEASE I. (vRELEASE I)
Proof-of-concept trial to assess the safety and tolerability of intranasal administration of a male donor memory T lymphocyte solution in females aged between 18 - 55 years of age.
- Trial name
- vRELEASE I (NCT06699758)
- Testing
- CD45RA- memory T lymphocytes cells sourced from healthy peripheral blood mononuclear cells male donors.
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Cristina Calvo Rey
Primary Progressive Aphasia, Semantic Dementia
Treatment for Speech and Language in Primary Progressive Aphasia
Primary progressive aphasia (PPA) is a progressive neurological disorder that causes a gradual decline in communication ability as a result of selective neurodegeneration of speech and language networks in the brain.
- Conditions
- Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia
- Trial name
- NCT04881617
- Testing
- Lexical Retrieval Training (LRT), Video-Implemented Script Training for Aphasia (VISTA)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
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