Clinical trials: Memory Loss
Patients With Cognitive Disturbances
Hippocampal Sclerosis and Amnesia Not Due to Alzheimer's Disease
Hippocampal Sclerosis (HS) leads to anterograde amnesia mimicking early Alzheimer's disease (AD) (so called HSA-nonAD). Recent studies showed that (a) the deficit of episodic memory as well as the level of hippocampal atrophy in…
- Trial name
- ShaTau7 (NCT02576821)
- Testing
- Neurological examinations, Neuropsychological examinations, Clinical examinations
- Where
- France
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Dementia, Alzheimer Disease
Care to Plan: a Tailored Resource for Family Members of Persons With Dementia
The present study will refine and conduct a preliminary efficacy evaluation of Care to Plan. Care to Plan is an online care planning tool that provides a succinct and clear overview of various types of dementia caregiver…
- Conditions
- Dementia, Alzheimer Disease, Memory Loss
- Trial name
- NCT03901456
- Testing
- Care to Plan, Usual Care
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Memory Loss, Memory Deficits
Screening for Memory Studies
We hope to recruit participants into various clinical trials and research projects.
- Conditions
- Memory Loss, Memory Deficits, Dementia, Alzheimer Disease
- Trial name
- NCT01123018
- Testing
- Memtrax Memory screening test
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Wesson Ashford Jr
Alzheimer Disease
Pregnenolone Sulfate an Early Marker of the Memory Loss in Alzheimer's Disease
The steroid pregnenolone sulfate (PREGS) may be one of the factors responsible for the memory decline related to normal aging or associated with Alzheimer's disease (AD).
- Trial name
- STERMEM (NCT00912886)
- Where
- 6 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aging Well, Memory Loss
Age Stereotype Priming and Social Participation
Memory performance is shown to be affected by age stereotypes among older adults. The purpose of the study is to examine the effects of age stereotype primes on episodic memory using priming intervention.
- Trial name
- ASPSP (NCT04202120)
- Testing
- Age-related stereotyping priming, Non age-related stereotype priming
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Alzheimer Disease, Anterograde Amnesia
Study of Repetitive Behaviors in Alzheimer's Disease
Alzheimer's disease (AD) is characterized by anterograde amnesia, the inability to memorize and remember events occurring after the cerebral lesion.
- Conditions
- Alzheimer Disease, Anterograde Amnesia, Anosognosia
- Trial name
- ECRA (NCT07732842)
- Where
- France
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Esquirol
Sentence Stimulus, Auditory Noise
Effects of Listening Effort on Sentence Processing and Memory (Study 1)
Sensorineural hearing loss (SNHL) is among the most prevalent chronic conditions in aging and has a profoundly negative effect on speech comprehension, leading to increased social isolation, reduced quality of life, and increased…
- Trial name
- NCT05584514
- Testing
- Sentence Stimulus, Auditory Noise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Utah
Post-Traumatic Stress Disorders, Anxiety
fMRI in Posttraumatic Stress Disorder (PTSD) During Working Memory Updating
Neuropsychological studies investigating trauma-exposed and posttraumatic stress disorder (PTSD) subjects have generally underlined the significantly poorer performance of tasks that require attention, concentration, and verbal…
- Conditions
- Post-Traumatic Stress Disorders, Anxiety, Amnesia, Dissociative
- Trial name
- METRAPI (NCT00288314)
- Testing
- Magnetic Resonance Imaging, Functional
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Aging, Memory Loss
Couples Health Aging, Rhythms and Sleep Study
Alzheimer's disease and related dementias (ADRD), including mild cognitive impairment (MCI), are becoming among the most prevalent causes of disability, death and healthcare costs worldwide.
- Trial name
- CHARMS (NCT05952284)
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cognitive Decline, Memory Loss
Effects of Music and Dance on Cognition, Frailty, and Burden in Elderly Caregivers Living in Rural Communities
This research aims to analyze the effects of senior dance on the cognition, frailty, and burden in elderly caregivers of rural communities.
- Conditions
- Cognitive Decline, Memory Loss, Frail Elderly Syndrome, Burden, Dependency
- Trial name
- NCT03068299
- Testing
- Dance, Health care guidance
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Epilepsy
fMRI Guided TMS Enhancement of Associative Memory Networks
This is a randomized, single-blinded, controlled phase 1 study to demonstrate feasibility and explore the neurophysiologic and clinical effects of repetitive transcranial magnetic stimulation (TMS) interventions in epilepsy…
- Trial name
- NCT02749422
- Testing
- MagStim RapidStim2
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Psychedelic Experiences, Amnesia
Pilot RECAP Study in Healthy Volunteers
The primary objective of the RECAP Study Program is to investigate the role played by conscious experience in the antidepressant effects of the psychedelic agent psilocybin.
- Trial name
- RECAP (NCT04842045)
- Testing
- Psilocybin and Midazolam
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cognitive Impairment, Mild, Cognitive Dysfunction
MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment
This is a randomized, double-blind, placebo-controlled, parallel group study. The use of placebo is appropriate to minimize bias related to treatment expectations of the subject, study partner, and site investigator, as well as…
- Conditions
- Cognitive Impairment, Mild, Cognitive Dysfunction, Amyloid Plaque, Neurodegenerative Disease, Hereditary
- Trial name
- NCT06177028
- Testing
- Lenalidomide 10 mg
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Healthy Participants
The Effective of Immersive Virtual Reality Distraction on Memory: Study 1
The effect of virtual reality on memory.
- Trial name
- NCT07172230
- Testing
- Immersive Virtual Reality, No distraction Control condition
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Washington
Anxiety and Fear
Memory and Fear Study (Fear of Memory Loss Study)
This study is a randomized control study to determine the impact of a tailored, web-based mindfulness program to reduce anxiety and increase the quality of life in older adults experiencing dementia-related fears, relative to a…
- Trial name
- NCT04821960
- Testing
- Tailored Mindfulness Program for Fear of Memory Loss, Conventional Mindfulness Program
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Anesthesia, Pain
Nitrous Oxide Neuroimaging
The purpose of this study is to determine the effects of acute pain on long-term memory and conditioned physiologic responses in the presence and absence of low dose nitrous oxide.
- Conditions
- Anesthesia, Pain, Amnesia
- Trial name
- NONI (NCT06702631)
- Testing
- Nitrous oxide, Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Keith M Vogt
Memory Loss, Age-Related Memory Disorders
Trial to Evaluate the Effectiveness of Memory Training Workshops in People From 65 to 80 Years
Randomized controlled trial to assess the effectiveness of a Memory Training Workshop in cognitive function, in terms of self-perceived memory, everyday memory and executive control abilities.
- Trial name
- NCT02431182
- Testing
- Memory Training Workshop
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Amnesia, Pain
Memory Modulation by Pain During Anesthesia
The purpose of this study is to determine the effects of pain on facilitating long-term auditory memory in the presence and absence of distinct intravenous anesthetics.
- Conditions
- Amnesia, Pain, Anesthesia
- Trial name
- MMA (NCT02515890)
- Testing
- Dexmedetomidine, Midazolam, Peripheral nerve stimulation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sleep Disturbance, Dementia
Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners
The purpose of this study is to determine if a 6-week videoconference intervention to teach skills to improve sleep is practical, acceptable, and helpful to persons living with memory loss, cognitive impairment, and/or dementia…
- Trial name
- SLEEPMATE (NCT06250725)
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Emory University
Dementia, Caregiver Burnout
WeCareAdvisor Study for Caregivers of People Living With Dementia
The WeCareAdvisor is an online tool to help caregivers manage behavioral and psychological symptoms of people living with dementia.
- Conditions
- Dementia, Caregiver Burnout, Caregiver Stress Syndrome, Alzheimer Disease
- Trial name
- NCT05012410
- Testing
- Immediate treatment group with High-Intensity Prompts, Immediate treatment group with Low-Intensity Prompts, Waitlist Control after three months with High-Intensity Prompts
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Drexel University