Clinical trials: Meniscectomy
Recovery Following Partial Medial Meniscectomy
Follow-up Study of Chondrogen® Delivered by Intra-Articular Injection Following Meniscectomy
The objective of the present study is to establish the long-term safety of an intra-articular injection of human mesenchymal stem cells (hMSCs) (Chondrogen).
- Trial name
- NCT00702741
- Testing
- Chondrogen
- Where
- 4 sites in United States
- Volunteers
- 55 people
- Sponsor
- Mesoblast International Sàrl
Meniscus Rupture, Meniscus Injury
Surgical Outcome After Displaced Bucket-handle Meniscal Lesions - Repair Versus Partial Meniscectomy
The menisci of the knee joint are structures composed of cartilage and connective tissue, whose primary functions are to stabilize the joint and distribute weight across joint surfaces.
- Conditions
- Meniscus Rupture, Meniscus Injury, Osteoarthritis of Knee
- Trial name
- NCT07079254
- Testing
- Meniscus suture, Partial meniscectomy
- Where
- 2 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Chondral Lesion Plus Partial Medial Meniscectomy
Mechanical vs. Radiofrequency-Based Debridement in the Treatment of Articular Cartilage Lesions
The purpose of this study is to evaluate changes in clinical and imaging outcomes following arthroscopic treatment of a single medial femoral chondral lesion plus partial medial meniscectomy by Radiofrequency-Based debridement or…
- Trial name
- ACT (NCT01803880)
- Testing
- Mechanical Debridement, RF-Based Debridement
- Where
- 7 sites in United States
- Volunteers
- 148 people
- Sponsor
- Smith & Nephew, Inc.
Meniscectomy
Muscle Weakness and Post-traumatic Knee OA
This is a single-center, randomized, single-blind (evaluator) study. Enrolled patients had a traumatic meniscal tear and underwent meniscectomy.
- Trial name
- NCT01879852
- Testing
- Quadriceps intensive strengthening, Standard rehabilitation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Florida
Meniscus Injury, Osteoarthritis, Knee
The Effect of Commercially Available Footwear Interventions in Meniscectomy Patients
Injuries to the meniscus are common in sport. A meniscectomy is often performed to manage symptoms associated with the meniscal injury. Following a meniscectomy individuals are highly likely to develop knee osteoarthritis (OA).
- Conditions
- Meniscus Injury, Osteoarthritis, Knee, Footwear
- Trial name
- MENI-FOOT (NCT03379415)
- Testing
- Footwear, Gait analysis
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Salford
Osteoarthritis, Knee, Meniscus Tear
Corticosteroid Meniscectomy Randomized Trial
Synovitis has an important role in the symptoms and progression of Osteoarthritis (OA). Inflamed synovium has been associated with both increased symptoms and increased progression in OA patients.
- Conditions
- Osteoarthritis, Knee, Meniscus Tear, Meniscus; Degeneration, Synovitis
- Trial name
- CoMeT (NCT04641351)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Postoperative Pain
Double-Blind, Multicenter, Study Comparing the Efficacy and Safety of OMS103HP With Vehicle Irrigation Solution in Subjects Undergoing Meniscectomy
The purpose of this study is to assess the benefit of OMS103HP for Injection (OMS103HP) compared with vehicle irrigation solution for prevention of pain and pain relief in subjects undergoing meniscectomy.
- Trial name
- C07-004 (NCT00624845)
- Testing
- OMS103HP, Vehicle
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- Omeros Corporation
Post Operative Pain
Acetaminophen Randomized Controlled Trial
Patients that are to undergo isolated meniscectomy will be randomized to 2 cohorts: one will take the FDA recommended dose of acetominophen (1000mg) 24hrs before surgery, one will be given a similarly looking placebo pill.
- Trial name
- NCT02737124
- Testing
- Acetaminophen
- Where
- United States
- Sponsor
- NYU Langone Health
Pain, Joint, Pain, Procedural
Saphenous Nerve Block for Partial Meniscectomy
Partial meniscectomy and meniscus repair are two of the most common orthopedic surgery procedures. As these procedures are being increasingly performed in ambulatory surgical centers, there has been a shift towards providing…
- Conditions
- Pain, Joint, Pain, Procedural, Meniscectomy
- Trial name
- NCT04717609
- Testing
- Saphenous Nerve Block, Ropivacaine injection
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Osteoarthritis
AMS Study: Inflammatory and Biomechanical Contributors to Arthritis Development Following Arthroscopic Meniscectomy
The purpose of this study is to examine the relationship between muscle activation and heart rate on joint generalized inflammation and arthritis development.
- Trial name
- NCT00752271
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Degenerative Meniscus Tear
The Benefit of Arthroscopic Partial Meniscectomy in Middle-Aged Patients
BACKGROUND Osteoarthritis (OA) is the most common form of arthritis and the knee is one of the most affected joints. The meniscus plays an important role in the development of knee OA.
- Trial name
- SLAMSHAM (NCT01264991)
- Testing
- Arthroscopic partial meniscectomy
- Where
- 2 sites in Denmark
- Volunteers
- 41 people
- Sponsor
- Slagelse Hospital
Degenerative Meniscal Tear
Surgical or Exercise Therapy on Patients With Degenerative Meniscus Tears
This study is conducted as a collaboration between NAR, Orthopedic Department, Oslo University Hospital,Ullevaal, Hjelp24Nimi Oslo, Martina Hansens Hospital Norway, and University of Southern Denmark, Odense, Denmark.
- Trial name
- OMEX (NCT01002794)
- Testing
- Arthroscopic partial menisectomy, Supervised neuromuscular and strength training
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Metabolic Syndrome, Meniscus; Degeneration
Metabolic Syndrome and Degenerate Meniscus Tears
The aim is to determine the outcomes of calorie-restricted diet and exercise intervention; libitum diet and waiting list control; early arthroscopic partial meniscectomy(APM) or delayed APM effect on MetS patients with Degenerate…
- Trial name
- NCT04837456
- Testing
- Calorie restricted diet and exercise intervention, libitum diet and waiting list control group, Early arthroscopic partial menisectomy group
- Where
- China
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Jingzhou
Post-Meniscectomy Pain Syndrome, Osteoarthritis, Knee
The SUN Clinical Trial (Safety Utilizing NUsurface Meniscus Implant)
The NUsurface® Meniscus Implant SUN Clinical Trial is a multi-center, single-arm, prospective, open label, non-randomized, observational clinical trial to gather safety and probable clinical benefit data on the NUsurface®…
- Trial name
- SUN (NCT02483988)
- Testing
- NUsurface® Meniscus Implant
- Where
- 13 sites in United States
- Volunteers
- 115 people
- Sponsor
- Phoenix Kinetics
Partial Meniscectomy, Knee Arthroscopic Surgery
Video-Based Education Versus In-Person Education in Patients Undergoing Arthroscopic Partial Meniscectomy
The primary aim of the study is to investigate whether video-based education and exercise-program is non-inferior to in-person instructions in improving pain-related self-efficacy in patients undergoing arthroscopic partial…
- Trial name
- NI-RCT (NCT07358325)
- Testing
- Video-based education, Usual Care
- Where
- Italy
- Volunteers
- 166 people
- Sponsor
- Istituto Clinico Humanitas
Meniscectomy
Telerehabilitation Following Meniscectomy
Telerehabilitation is a form of tele-treatment in which rehabilitation services are dispensed at patients' home utilizing video telecommunication services with real-time synchronous exchange of information.
- Trial name
- NCT04644640
- Testing
- Telerehabilitation Therapy, In-person Rehabilitation Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Meniscal Injuries, Meniscal Tear
Semitendinosus Autograft vs Meniscal Allograft in Post-Meniscectomy Syndrome
This multicenter, stratified, partially randomized clinical trial aims to compare autologous semitendinosus tendon graft and meniscal allograft transplantation (MAT) in young adults with post-meniscectomy syndrome.
- Conditions
- Meniscal Injuries, Meniscal Tear, Meniscus Lesion
- Trial name
- MAT (NCT07204587)
- Testing
- Autologous Semitendinosus Tendon Graft, Meniscal Allograft Transplantation (MAT)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Multimodal Analgesia, Nonsteroidal Anti-inflammatory Drugs
NSAID vs. Narcotics
This will be a single-center, prospective observational study. The study will compare post-operative pain scores and narcotic consumption between two groups of patients - one cohort will receive ibuprofen (Motrin) and Percocet…
- Trial name
- NCT02915055
- Testing
- Ibuprofen 600 mg, standard oxycodone/acetaminophen
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Lesion of the Medial Meniscus
Gait Analysis Meniscal Repair
In the past it was shown, that medial partial meniscectomy (MPM) leads to an increase of the knee adduction moment (KAM) during walking.
- Trial name
- NCT02474004
- Testing
- medial meniscal surgery
- Where
- 2 sites in Austria
- Volunteers
- 30 people
- Sponsor
- Michael Liebensteiner
ACL Repair, Meniscectomy
Efficacy Study of Continuous Intraarticular Infusion in Patients Undergoing Arthroscopic Knee and Shoulder Operations
The aim of this study is to determine whether the continuous intraarticular infusion of local anesthetics in the postoperative period can improve analgesia and patients satisfaction after knee and shoulder arthroscopy.
- Conditions
- ACL Repair, Meniscectomy, Bankart Repair
- Trial name
- NCT00314457
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Children's Hospital of Philadelphia