Clinical trials: Menopausal
Menopause and Genitourinary Syndrome
Effect of CBD-Based Vaginal Suppositories on Menopausal Symptoms
Efficacy and safety of the medical device CANNEFF® vaginal suppositories containing two active ingredients cannabidiol (CBD) and hyaluronic acid (HA) in alleviating menopausal symptoms and improving quality of life in…
- Trial name
- Gyno-CBD (NCT06804889)
- Testing
- CANNEFF® VAG SUP vaginal suppositories
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Palacky University
Menopause
Menopausal Health Training for Husbands on Women's Quality of Life and Marital Satisfaction
The investigators conducted a clinical trial to evaluation the effect of a menopausal health training for Husbands of 45-60 years women on the women's quality of life and marital satisfaction during transitional period to…
- Trial name
- NCT02496338
- Testing
- Training program about menopausal health isues
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gonabad University of Medical Sciences
Osteoporosis
A Study of the Clinical Safety, Tolerability, and Efficacy of Zoledronic Acid Compared to an Oral Bisphosphonate
The purpose of this trial is to study the clinical safety, tolerability, and efficacy of zoledronic acid compared to an oral bisphosphonate in postmenopausal women with osteoporosis.
- Trial name
- NCT00100555
- Testing
- zoledronic acid
- Where
- 18 sites in United States
- Volunteers
- 120 people
- Sponsor
- Novartis Pharmaceuticals
Menopause, Gait, Unsteady
Effects of Strength Training on the Gait and Pelvic Floor in Menopausal Women
The overall objective will be to observe whether a strength and balance training intervention produces significant changes in the analysis of double stance phase movement during gait, the analysis of coxofemoral, tibial and…
- Conditions
- Menopause, Gait, Unsteady, Pelvic Floor Disorders
- Trial name
- NCT07824947
- Testing
- Strength training
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Menopause, Postmenopausal Disorder
Metabotyping in the Postmenopausal Stage
Menopause is defined as the absence of menstrual periods for twelve consecutive months. Although the onset may vary, natural menopause occurs between the ages of 45 and 55 and is considered a stage in the aging process for women.
- Conditions
- Menopause, Postmenopausal Disorder, Postmenopausal Symptoms
- Trial name
- SHE-HEALTH (NCT05397015)
- Testing
- No intervention will be done
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Menopause
Assessment of Menopause Related Quality of Life Among Health Professionals in University Hospitals of UMC in Nur-Sultan
This study aims to investigate the quality of life of menopausal health-care providers in University Medical Center (UMC) hospitals in Nur-Sultan and identify whether there is a difference in the quality of life between two major…
- Trial name
- NCT04724135
- Testing
- Survey
- Volunteers
- 320 people
- Sponsor
- Nazarbayev University Medical Center
Metastatic Breast Cancer
Palbociclib (PD-0332991) Combined With Fulvestrant In Hormone Receptor+ HER2-Negative Metastatic Breast Cancer After Endocrine Failure (PALOMA-3)
The study is a randomized, double blind, placebo controlled, Phase 3 clinical trial with the primary objective of demonstrating the superiority of palbociclib in combination with fulvestrant (Faslodex®) over fulvestrant alone in…
- Trial name
- NCT01942135
- Testing
- Palbociclib, Fulvestrant
- Where
- 247 sites in United States, Australia and 15 more
- Volunteers
- 521 people
- Sponsor
- Pfizer
Chronic Venous Insufficiency
Efficacy Study of Kinesio Taping to Treat Muscular and Joint Problems in Chronic Venous Insufficiency
The purpose of this study is to analyze the effects of Kinesio Taping on gastrocnemius muscle activation during gait and on Range of ankle motion in postmenopausal females with Chronic Venous Insufficiency in initial stages in…
- Trial name
- NCT01501188
- Testing
- Kinesio Taping
- Where
- Spain
- Volunteers
- 259 people
- Sponsor
- Universidad de Granada
Fatigue
Effect of Pilates Exercises On Fatigue In Post Menopausal Women
Pilates is a system of exercises using special apparatus, designed to improve physical strength, flexibility, and enhance mental awareness.
- Trial name
- NCT05002894
- Testing
- Pilates exercises, medical standard care for fatigue
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Menopause, Sleep Disorder
the Effects of Different Therapy Regimens on Menopausal Sleep Disorders
Sleeping disorders are one of the most common menopausal symptoms, which seriously affect health and life quality of perimenopausal women.
- Trial name
- NCT06117969
- Testing
- Tibolone, Xiangshao granules, Tibolone plus Xiangshao granules
- Volunteers
- 180 people
- Sponsor
- Peking Union Medical College Hospital
Metastatic Breast Adenocarcinoma, Breast Cancer
CR1447 in Endocrine Responsive-HER2neg and TN-ARpos Breast Cancer
SAKK 21/12 is a stratified, multicenter Phase II first in-human trial with transdermal CR1447 (4-OH-testosterone) and is directed to patients with endocrine responsive-HER2neg and TN-ARpos metastatic or locally advanced breast…
- Trial name
- NCT02067741
- Testing
- CR1447
- Where
- 13 sites in Switzerland
- Volunteers
- 29 people
- Sponsor
- Swiss Cancer Institute
Postmenopausal Osteoporosis
PRIOR Study - A Study of Ibandronate (Boniva) in Postmenopausal Women With Osteoporosis or Osteopenia
The purpose of this study is to evaluate treatment adherence to different regimens of ibandronate in postmenopausal women with osteoporosis or osteopenia who are intolerant to daily or weekly alendronate or risedronate therapy…
- Trial name
- NCT02598453
- Testing
- Ibandronate
- Where
- 60 sites in United States
- Volunteers
- 545 people
- Sponsor
- Hoffmann-La Roche
Female Sexual Dysfunction
Study To Investigate Effect Of A New Drug (PF-00446687) In Post-Menopausal Women Who Suffer From Sexual Dysfunction.
The purpose of this study is to investigate the effect of up to 200 mg of PF-00446687 on acute sexual arousal and sexual interest in post menopausal females, as well as examining the safety and toleration of the drug.
- Trial name
- NCT00479570
- Testing
- PF-00446687
- Where
- 3 sites in Denmark, Norway and 1 more
- Volunteers
- 23 people
- Sponsor
- Pfizer
Breast Cancer, Hot Flashes
Hormone Replacement Therapy for Hot Flashes and/or Vaginal Symptoms in Postmenopausal Women Receiving Tamoxifen for Breast Cancer
RATIONALE: Hormone replacement therapy may be effective in managing the hot flashes and/or vaginal symptoms in postmenopausal women who are receiving tamoxifen for breast cancer.
- Conditions
- Breast Cancer, Hot Flashes, Menopausal Symptoms
- Trial name
- NCT00026286
- Testing
- conjugated estrogens, medroxyprogesterone
- Where
- 24 sites in United States
- Sponsor
- Eastern Cooperative Oncology Group
Advanced ER-Positive HER2-Negative Breast Cancer
A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer
This study is randomized, open-label, parallel-group, multicentre Phase 2 study aimed to compare the efficacy and safety of oral AZD9833 versus intramuscular (IM) fulvestrant in women with advanced breast cancer.
- Trial name
- SERENA-2 (NCT04214288)
- Testing
- AZD9833, Fulvestrant
- Where
- 85 sites in United States, Belgium and 14 more
- Volunteers
- 240 people
- Sponsor
- AstraZeneca
Combat Disorders
Prospective Study of Veteran Health in Previously Deployed Soldiers
Background: Previous deployments like that to the Persian Gulf in 1991 produced veterans with post-deployment symptom-based health problems with no medical explanation.
- Trial name
- NCT00285246
- Where
- 2 sites in United States
- Volunteers
- 838 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Metabolic Syndrome
Early Vascular Wall Changes by Magnetic Resonance Imaging (MRI) in Metabolic Syndrome Versus Metabolically Normal Pre-Menopausal Women: A Pilot Study
The purpose of this study is to compare the vascular permeability of blood vessel walls (of the carotid artery) in pre-menopausal women who have metabolic syndrome (syndrome of having at least 3/5 following features- increased…
- Trial name
- NCT01068535
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Washington
Chronic Insomnia During Perimenopause and Menopause
Clinical Efficacy of Thumbtack Needle for Chronic Insomnia in Perimenopausal and Menopausal Women
A multicenter, randomized, controlled, blinded clinical trial was conducted to evaluate the effects of thumbtack needle on sleep in patients with chronic insomnia during perimenopause and menopause.
- Trial name
- NCT07229976
- Testing
- thumbtack needle
- Where
- 8 sites in China
- Volunteers
- 198 people
- Sponsor
- Huazhong University of Science and Technology
Hot Flushes, Vasomotor Symptoms
A Study of MF101 in Postmenopausal Women
This phase 3a study is designed to assess the safety and efficacy of MF101 on the frequency of moderate to severe hot flushes in postmenopausal women.
- Trial name
- HERBA (NCT00906308)
- Testing
- MF101 5 g/day, MF101 10 g/day
- Where
- 50 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Bionovo
Osteoporosis, Metabolic Syndrome
Body Composition and Risk for Development of Pre-diabetes in Post-menopausal Chinese Women in Singapore
This project aims to ascertain that novel imaging and metabolic markers can be used to identify as well as to validate and improve the detection of Singapore-Chinese women at increased risk of diabetes.
- Trial name
- NCT03503552
- Where
- Singapore
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- JeyaKumar Henry
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