Clinical trials: Menopausal Depression
Hysterectomy
Post-Hysterectomy Nursing Support Program
Objective: This study was conducted to evaluate the effectiveness of the nursing support program developed for women undergoing hysterectomy.
- Trial name
- NCT05063864
- Testing
- Nursing Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Suleyman Demirel University
Osteoporosis, Osteopenia
Melatonin Osteoporosis Prevention Study
Osteoporosis is one of the most common skeletal disorders. Today in the United States, 10 million individuals have osteoporosis and 34 million more have low bone mass or osteopenia, which places them at an increased risk of some…
- Trial name
- MOPS (NCT01152580)
- Testing
- melatonin, sugar pill
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Postpartum Depression, Major Depressive Disorder
Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression
The project aimed at identifying neuropsychobiological signatures of pharmacological sex-steroid hormone manipulations in healthy women as a risk model for depression.
- Conditions
- Postpartum Depression, Major Depressive Disorder, Postpartum Psychosis, Menopause
- Trial name
- GnRHa (NCT02661789)
- Testing
- Goserelin 3.6 mg implant
- Where
- Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Gitte Moos Knudsen
Insomnia, Depressive Symptoms
IMB-Based Sleep Hygiene Education for Menopausal Women: Effects on Sleep Quality and Depression
This study aims to evaluate the effects of sleep hygiene education on sleep quality and depression in women during menopause. Women will be randomly assigned to either an education group or a control group.
- Trial name
- NCT07299903
- Testing
- Sleep Hygiene Education
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Ankara Yildirim Beyazıt University
Cardiovascular Diseases, Heart Diseases
Epidemiology of Cardiovascular Risk Factors in Women (Healthy Women Study)
To determine cardiovascular risk factors and the change in risk factors during and following the menopause.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Depression, Carotid Artery Diseases
- Trial name
- NCT00005160
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Edema, Depression
Safety and Efficacy Study of Gamaline+Hipericin in PMS
GAMALINE is already register for PMS and HIPERICIN as antidepressive drug. Both plant extracts. The investigators will try the mixture and see if the vasomotor symptoms will disappear.
- Conditions
- Edema, Depression, Hot Flashes, Anxiety
- Trial name
- GH (NCT01283568)
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Phytopharm Consulting Brazil
Perimenopause, Menopause
Perimenopausal Estrogen Replacement Therapy Study
Study Background and Objectives: In the U.S. the majority of heart disease deaths are in women, not men. Much of the gender disparity in CVD rates relate to the burden of CV risk in women after the menopause.
- Conditions
- Perimenopause, Menopause, Depression
- Trial name
- PERT (NCT01308814)
- Testing
- Estradiol
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Menopause, Depression
Brain Imaging Study in Menopausal Women With and Without Major Depressive Disorder
The purpose this study is to measure cortical gama-aminobutyric acid levels (GABA) levels in menopausal women with major depressive disorder and healthy subjects using nuclear magnetic resonance spectroscopy (MRS).
- Trial name
- NCT00626340
- Testing
- MDD diagnosis and Estrogen treatment, MDD diagnosis and Fluoxetine treatment, MDD diagnosis with both Estrogen and Fluoxetine treatment
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Perimenopause, Perimenopause-Related Depression
Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This observational study examines the safety and effects of injecting Muse cells (a type of naturally occurring stem like cells found in adult tissues such as fat or bone marrow) directly into the ovaries of women aged 28 to 70…
- Conditions
- Perimenopause, Perimenopause-Related Depression, Premature Ovarian Insufficiency, Premature Ovarian Failure (POF)
- Trial name
- MUSE-OVARY (NCT07511660)
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Healthy, Perimenopausal Depression
Multidimensional Determinants of Functional Health In Women Aged 45-60
The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years.
- Conditions
- Healthy, Perimenopausal Depression, Menopausal Complaints, Bone Mineral Density
- Trial name
- NCT07667699
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kartal City Hospital
Depression, Menopause
Vortioxetine for Menopausal Depression
The broad goal of this study was to examine the efficacy and tolerability of vortioxetine (flexible dose) for the treatment of major depressive disorder (MDD) in symptomatic women around the menopausal transition.
- Conditions
- Depression, Menopause, Vasomotor Disturbance, Hot Flashes
- Trial name
- NCT02234362
- Testing
- vortioxetine
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Massachusetts General Hospital
Depressive Disorder, Healthy
The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders
The normal menstrual cycle is produced by a series of hormonal signals that starts with the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus.
- Conditions
- Depressive Disorder, Healthy, Mental Disorders, Mood Disorders
- Trial name
- NCT00001232
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Menopause, Menopausal Symptoms
Meleis' Transition Theory-Based Education and Counseling Program in Menopausal Women
This randomized controlled trial aims to evaluate the effectiveness of a Meleis' Transition Theory-based education and counseling program on menopausal symptoms, perimenopausal depression, and menopause-specific quality of life…
- Conditions
- Menopause, Menopausal Symptoms, Perimenopausal Depression
- Trial name
- NCT07657078
- Testing
- Meleis' Transition Theory-Based Education and Counseling Program, Standard Information
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Ankara Medipol University
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Menopausal Depression
Cognitive Behavioural Therapy for Menopausal Symptoms
This study examined the effectiveness of a new cognitive-behavioural therapy for menopausal symptoms (CBT-Meno). Half of participants were randomly assigned to the 12-week CBT-Meno program and half to a 12-week waitlist.
- Trial name
- CBTMENO (NCT02480192)
- Testing
- CBT for Menopausal Symptoms (CBT-Meno)
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Depression, Insomnia
Cognitive Behavioral Therapy for Insomnia and Depression Among Menopausal Women
Considering physical and psychological problems that threaten women during the menopausal period, it seems that therapies that can help women cope with these problems, especially psychological ones, will be useful.
- Conditions
- Depression, Insomnia, Cognitive Behavioral Therapy, Menopausal Depression
- Trial name
- NCT05920460
- Testing
- Cognitive Behavioral Therapy Program
- Where
- 2 sites in Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Perimenopause, PMDD
Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause
Transcutaneous Auricular Neurostimulation (tAN) will be administered to women with premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and perimenopause.
- Trial name
- NCT07688720
- Testing
- transcutaneous auricular neurostimulation (tAN)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Texas Christian University
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Menopausal Women
The Effect of Value Clarification Based on Meleis's Transition Theory on Menopausal Symptoms, Depression, Anxiety, Stress, and Quality of Life in Perimenopausal Women
Menopause is a life stage influenced not only by hormonal factors but also by psychological, social, and cultural factors. Symptoms such as hot flashes, sleep problems, and mood changes may occur, and their severity depends on…
- Trial name
- NCT07584109
- Testing
- value clarification, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ordu University
Moderate Depression, Menopausal and Postmenopausal Disorders
Homeopathic Treatment for Depression in Peri- and Postmenopausal Women
The aim of this study was to determine whether individualized homeopathic treatment and fluoxetine are more efficient than placebo for moderate to severe depression in peri- and postmenopausal women.
- Trial name
- HOMDEP-MENOP (NCT01635218)
- Testing
- Individualized homeopathic treatment, Fluoxetine
- Where
- Mexico
- Volunteers
- 133 people
- Sponsor
- Hospital Juarez de Mexico