Clinical trials: Menopause
Menopause, Sleep Quality
Effect of Menopausal Hormone Therapy on Sleep
The Effect of Menopausal Hormone Therapy on Sleep (menoSLEEP) study is investigating the effects of menopausal hormone therapy (MHT) on sleep problems in peri- and postmenopausal women with an indication for MHT.
- Conditions
- Menopause, Sleep Quality, Psychological Wellbeing
- Trial name
- menoSLEEP (NCT07674316)
- Testing
- HRT
- Where
- Switzerland
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Breast Cancer
Using Technology to Improve Physical Activity Levels Among Postmenopausal Women (The Active & Aware Study)
Women who are overweight or do not exercise are at higher risk for breast cancer after menopause. This study will test a new electronic device that measures the body's movement and works alongside a website to help women increase…
- Trial name
- NCT01837147
- Testing
- Technology-Based Physical Activity Promotion, Pedometer Intervention
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Corneal Deformity, Macular Degeneration Advanced
Comparison of Ocular Changes by Surgical Menopause Using Optical Coherence Tomography (OCT)
The aim of this study is to investigate the early changes in macular thickness, corneal thickness and intraocular pressure in young women undergoing surgical menopause.
- Conditions
- Corneal Deformity, Macular Degeneration Advanced, Surgical Menopause
- Trial name
- NCT05920655
- Testing
- Optic coherence tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Batman Training and Research Hospital
Effects of Chemotherapy
Assessing Fertility Potential in Female Cancer Survivors
Hypothesis: Girls and women exposed to chemotherapy and/or radiation therapy experience endocrine changes more similar to women in their late reproductive years than to same-age peers.
- Trial name
- NCT01143844
- Where
- 2 sites in United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sexual Dysfunction
Motivational Interviews With Women Experiencing Sexual Dysfunction During Menopause Period
The aim of this study is to evaluate the effect of motivational interviews with women who experience sexual dysfunction during menopause on sexual quality of life and self-efficacy.The population of the study consisted of…
- Trial name
- NCT06337058
- Testing
- Experimental group (motivational interview)
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Hülya KAMALAK
Osteoporosis, Post-Menopausal
Combination Osteogenic Therapy in Established Osteoporosis
This study is designed to determine if combining parathyroid (PTH 1-34) with fluoride (MFPSR) therapy in a cyclic treatment regimen will: (1) produce a greater increase in bone density of the spine than would be produced by…
- Trial name
- NCT00018447
- Testing
- PTH 1-34, MFPSR-fluoride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hot Flashes
Safety and Efficacy of Dr. Tagliaferri's Menopause Formula
The primary goal of this study is to evaluate the safety and efficacy of 12 weeks of treatment of 4 grams/day of Dr. Tagliaferri's Menopause Formula (administered as 2 grams PO BID) in reducing the frequency of menopausal…
- Trial name
- NCT01957306
- Testing
- Dr. Tagliaferri's Menopause Formula
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herba Buena, Inc
Perimenopause, Perimenopausal Women
12-week Multi-vitamin/Mineral Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being.
Perimenopause is a stage of transition into menopause that is marked by menopausal symptoms while menstruation is still taking place.
- Conditions
- Perimenopause, Perimenopausal Women, Perimenopause, Climacteric Syndrome
- Trial name
- NCT07242430
- Testing
- Multivitamin/mineral supplement
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Coronary Artery Disease, Genetic Predisposition to Disease
Genetic Risk Stratification for Primary Prevention of CAD in Men and Pre & Post-menopausal Women
The investigators propose to genotype males and females at age 40 years and older, who are asymptomatic and without known heart disease (N=2000).
- Trial name
- NCT05169840
- Testing
- Genetic Risk Score for Coronary Artery Disease
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Strength Training Effects, Menopausal Women
Building Strength for Menopause
A pilot study investigating whether heavy resistance training is enjoyable, acceptable, and feasible for middle-aged women undergoing the menopausal transition.
- Conditions
- Strength Training Effects, Menopausal Women, Cognitive Function
- Trial name
- NCT06813404
- Testing
- Heavy resistance training, Yoga
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northeastern University
Menopausal Symptoms
A Clinical Trial on the Efficacy of a Combination Herbal Product, Biotropics' Nu Femme, on Menopausal Symptoms and Quality of Life in Women
The purpose of this study is to assess the effectiveness of an herbal combination product called Nu Femme, on menopausal symptoms in peri-menopausal women.
- Trial name
- 14NMHB (NCT02269891)
- Testing
- Nu Femme
- Where
- 4 sites in Canada
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Healthy, Premenopausal Period
Effects of Omega-3 Fatty Acids on Risk Factors for Breast Cancer in Pre-menopausal Women
Healthy premenopausal women were enrolled in a diet intervention study that examined the effect of a combination EPA/DHA supplement on risk factors associated with breast cancer.
- Trial name
- NCT02816125
- Testing
- omega-3 fatty acid
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Contraception
To Investigate the Pharmacological Effects, Drug Blood Levels and Safety of an Intrauterine System Releasing the Study Drug BAY1007626 in Comparison to Mirena and Jaydess in Healthy Young Women Treated for 90 Days to Determine the Drug Dose for Further Development
Investigation of pharmacological effects, drug blood levels and safety of an intrauterine system releasing the study drug BAY1007626 in comparison to Mirena and Jaydess in healthy young women treated for 90 days to determine the…
- Trial name
- NCT02490774
- Testing
- BAY1007626, Jaydess, Mirena
- Where
- 7 sites in Germany, Netherlands and 1 more
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Bayer
Menopausal Symptoms
Randomized Placebo Controlled Clinical Study of an Oral Product in Subjects With Menopausal Symptoms
The objective of this study is to assess the safety and effectiveness of a dietary supplement for symptom relief in subjects with menopausal symptoms over the course of five weeks of continuous daily use.
- Trial name
- NCT06787443
- Testing
- Dietary Supplement with Proprietary Herbal Extract Blend and GABA
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Primary Ovarian Insufficiency, Premature Menopause
Injections of Autologous PRP in Women With Primary Ovarian Insufficiency
Premature ovarian failure is a loss of normal function before age 40, leading to infertility and hypoestrogenism. This study will involve only adult women with a diagnosis of POI.
- Trial name
- PRP4POI (NCT03542708)
- Testing
- A-PRP
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Postmenopause
Use of the Synthetic Hormone CDB-2914 in Treating Symptoms of Menopause
This study will examine the safety and effectiveness of a synthetic hormone, CDB-2914, for treating symptoms of menopause. It will compare the effects of estrogen and CDB-2914 with those of estrogen and progesterone in…
- Trial name
- NCT00009659
- Testing
- CDB 2914
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Body Weight Changes, Habits, Diet
Innovations Applied to the Pyrenean Beef Production to Enhance Consumer-identifiable Meat.
The DIETAPYR2 study is a randomized controlled crossover trial consisting of two experimental periods each lasting 8 weeks. Enrolled participants were randomly assigned to either a Pyrenean beef-based diet or a conventional…
- Conditions
- Body Weight Changes, Habits, Diet, Habit, Food, Life Change Events
- Trial name
- DIETAPYR2 (NCT04832217)
- Testing
- Pyrenees´ Beef diet
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Major Depressive Disorder, Menopausal Staging and Vasomotor Symptoms (for Females)
Desvenlafaxine Succinate (DVS) for Major Depressive Disorder (MDD) in Midlife Men and Women
The main objective of this study is to characterize a range of brain activation symptoms associated with depression and response to treatment in midlife men and women with MDD, using MRI and functional MRI.
- Trial name
- DVS (NCT00888862)
- Testing
- Desvenlafaxine Succinate
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Post-menopausal Osteoporosis
Bone Healing in Healthy and Post-menopausal Osteoporotic Women
Both the pathogenesis and the treatment of osteoporosis may potentially interfere at different levels on the multi-stage complex cascade of events involved in bone healing/regeneration.
- Trial name
- NCT01826656
- Testing
- tooth extraction, CBCT scan, DXA scan
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University College, London
Breast Cancer, Hot Flashes
Effect of Non-estrogenic Pollen Extract PCC-100 on Hot Flushes
Many postmenopausal women have vasomotor symptoms during adjuvant hormonal treatment for breast cancer. PCC-100 is a pollen extract used for alleviation of postmenopausal symptoms.
- Conditions
- Breast Cancer, Hot Flashes, Postmenopausal Symptoms
- Trial name
- NCT03684096
- Testing
- non-estrogenic pollen extract PCC-100
- Where
- Belgium
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent