Clinical trials: Menopause
Menopause
Choline Dose Ranging in Postmenopausal Women
This study will use a randomized placebo-controlled trial to examine smaller doses of choline and whether a signal in the brain is detectable using fMRI.
- Trial name
- NCT06924541
- Testing
- Choline
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Julie Dumas
Stage IV Non-small Cell Lung Cancer
Exemestane, Pemetrexed Disodium, and Carboplatin in Treating Post-Menopausal Women With Stage IV Non-Small Cell Lung Cancer
This phase I trial studies the side effects and best dose of exemestane in combination with pemetrexed disodium and carboplatin in treating post-menopausal women with stage IV non-small cell lung cancer.
- Trial name
- NCT01664754
- Testing
- exemestane, pemetrexed disodium, carboplatin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Postmenopausal Osteoporosis
Study of Post Menopausal Osteoporosis (PMO) Among Gynecology Outpatients in Pakistan
This observational study will provide an opportunity to document local patterns of susceptibility, patient profile, and usefulness of screening in postmenopausal patients coming to gynecology outpatient clinics in Pakistan.
- Trial name
- NCT02422069
- Where
- 8 sites in Pakistan
- Volunteers
- 624 people
- Sponsor
- Hoffmann-La Roche
Menopause, Hypertension
The Effects of Swimming on Elderly Women With Stage-2 Hypertension
Aging is associated with progressive decreases in arterial health and function as well as overall fitness. It is crucial to prevent or reduce the negative effects of aging on the vasculature and fitness components by implementing…
- Trial name
- NCT03546270
- Testing
- Swimming
- Volunteers
- 100 people
- Sponsor
- Pusan National University
Advanced Breast Cancer
AZD2171 in Addition to Fulvestrant in Patients With Advanced Breast Cancer.
The purpose of this study is to determine whether AZD2171 can effectively improve time to tumour progression when added to fulvestrant in patients with advanced hormone sensitive breast cancer who progressed on prior hormonal…
- Trial name
- NCT00454805
- Testing
- AZD2171, Fulvestrant
- Where
- 16 sites in United States, Australia and 1 more
- Volunteers
- 75 people
- Sponsor
- AstraZeneca
Infertility (IVF Patients)
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.
The goal of this multicenter, randomized, placebo-controlled, double-blind clinical trial is toto evaluate the efficacy and safety of a human menopausal gonadotropin (hMG) in the development of multiple follicles, pregnancy, and…
- Trial name
- GRACE (NCT07216742)
- Testing
- hMG subcutaneous injection
- Where
- 16 sites in United States
- Volunteers
- 659 people
- Sponsor
- Granata Bio Corporation
Obesity, Menopause
Obesity Prevention After Smoking Cessation in Menopause
This study addresses the high risk of weight gain associated with smoking cessation in women. The obesity prevention pilot study is designed for the primary prevention of weight gain that can lead to overweight in normal-weight…
- Trial name
- NCT00064961
- Testing
- Individualized dietary-control and exercise program, Weight-management and smoking cessation maintenance, Smoking Cessation program
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Menopause
Vasomotor Symptoms (VMS) Progesterone Study: Vasomotor Symptoms and Endothelial Function - Trial of Oral Micronized Progesterone
The primary purpose of this study is to determine the effects of a full dose (300 mg at hs) of oral micronized progesterone (OMP) on vasomotor symptoms [VMS] (hot flushes/night sweats), on forearm blood flow and on lipid levels…
- Trial name
- NCT00152438
- Testing
- Oral Micronized Progesterone (Prometrium®)
- Where
- Canada
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Menopause, Hot Flashes
Study Evaluating DVS-233 SR to Treat Vasomotor Systems Associated With Menopause
The purpose of this study is to assess the safety and efficacy of desvenlafaxine succinate (DVS) for treatment of moderate to severe vasomotor symptoms (VMS) that are associated with menopause, and also to assess the effects of…
- Conditions
- Menopause, Hot Flashes, Sleep Disorders
- Trial name
- NCT00256685
- Testing
- DVS-233 SR
- Volunteers
- 568 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Skin Aging, Quality of Life
Effect of DHEA on Skin Aging in Postmenopausal Women
The purpose of the study is to determine the response of skin parameters related to skin aging to the local action of DHEA in postmenopausal women.
- Trial name
- NCT00248989
- Testing
- Dehydroepiandrosterone
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Cardiovascular Risk Factor, Vascular Function
Abertay Tea for Cardiovascular Health During Menopause
The regular consumption of seaweed, as observed in Japan, is associated to a reduced cardiovascular risk and prolonged life expectancy.
- Trial name
- AberTeaM (NCT07070635)
- Testing
- Nutritional intervention with Fermented Seaweed Enriched English Breakfast Tea, Nutritional intervention with Control English Breakfast Tea
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Abertay University
Menopause
Electro-acupuncture for Menopausal Transition Symptoms
This trial aimed at exploring the efficacy as well as safety of electro-acupuncture for MT symptoms.
- Trial name
- NCT02471755
- Testing
- Eelectro-acupuncture
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Menopause Hot Flashes
Fezolinetant and Vascular Health and Brain Health
The goal of this clinical trial is to learn whether a study drug called fezolinetant impacts cardiovascular and cognitive health in women who have moderate to severe menopausal hot flashes and night sweats.
- Trial name
- FAVES-B (NCT07606664)
- Testing
- Fezolinetant
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Rebecca Thurston
Menopause
The Influence of the "Washoku" Diet on the Gut Microbiota in Postmenopausal Women
Menopause is a special period in a woman's life, when a sudden drop in estrogen levels leads to the cessation of menstrual cycles.
- Trial name
- NCT06673199
- Testing
- Washoku diet
- Where
- Poland
- Volunteers
- 35 people
- Sponsor
- Joanna Bajerska
Perimenopausal Bleeding
Different Modalities for the Evaluation of Patients With Peri-menopausal Bleeding
The study aims to compare between 3D ultrasonography and hysteroscopy for the evaluation of cases with Peri-menopausal bleeding
- Trial name
- NCT07309692
- Testing
- three dimensional ultrasonography, Hysteroscopy
- Where
- Egypt
- Volunteers
- 106 people
- Sponsor
- Sohag University
Breast Cancer
Surgical Breast Resection With or Without Axillary Lymph Node Excision in Treating Women With Breast Cancer
This randomized phase III trial is studying surgery and axillary lymph node dissection to evaluate if systematic Axillary Lymph Node Excision can be avoided in locoregional treatment for operable breast cancer smaller than 10 mm…
- Trial name
- AXIL95 (NCT00210236)
- Testing
- Conventional surgery WITHOUT Axillary Lymph Node Excision, Conventional surgery WITH Axillary Lymph Node Excision
- Where
- 14 sites in France
- Volunteers
- 625 people
- Sponsor
- Institut Bergonié
Menopause
Study to Investigate the Effectiveness of a Food Supplement Made of Hop in the Improvement of Menopausal Symptoms
This observational study will assess the effects of a dietary supplement based on Humulus Lupulus L. to relieve the symptoms of menopause in perimenopausal and postmenopausal women, by doing a follow up of the Cervantes scale and…
- Trial name
- OLSEM (NCT03875430)
- Testing
- Humulus lupulus L
- Volunteers
- 443 people
- Sponsor
- Aristo Pharma Iberia
Energy Expenditure, Appetite, Energy Intake, Food Reward Menopause Transition
Effects of Hormonal STatus on Energy Expenditure and Feeding behAvior in woMen(ESTEAM)
The health of women throughout their lives and especially during aging is a subject at the heart of current health issues. Indeed, hormonal variations during a woman's life condition her reproductive life, but also her…
- Trial name
- ESTEAM (NCT05935046)
- Testing
- Walk test and meal test
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Postmenopausal Period
The Effect of High Intensity Functional Exercise Programs on Menopausal Symptoms, Physical Performance, and Dual Task Performance in Postmenopausal Women
This study was conducted to examine the effects of exercise programs on the physical and psychosocial health of postmenopausal women.
- Trial name
- HIFT-PM (NCT07471620)
- Testing
- High-intensity functional exercise, moderate to low intensity exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Menopause, Menopause Related Conditions
Pragmatic Weight Loss Intervention During Menopause
The investigators are using a community-based participatory research (CBPR) model to develop a lifestyle intervention targeting weight loss that is specifically tailored to women in perimenopause.
- Trial name
- WISE (NCT04487782)
- Testing
- Focus Groups
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Kara Marlatt
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