Clinical trials: Menopause
Menopause
Relationship Between Genitourinary and Respiratory Symptoms in Postmanopause
The aim of this study is to evaluate the relationship between genitourinary system symptoms and respiratory function and respiratory muscle strength in postmenopausal women.
- Trial name
- NCT07651566
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Halic University
Menopause Syndrome
Evaluation of the Efficacy and Safety of A High Molecular Weight, Natural Hyaluronic Acid Vaginal Gel in Women With Genitourinary Syndrome of Menopause
The aim of the study is to evaluate the safety and efficacy of the vaginal gel with HMW HA in women with genitourinary syndromes due to either menopause or other causes such as the patients after ovarian or breast cancer…
- Trial name
- NCT05263102
- Testing
- Vaginal Moisturizing Gel
- Where
- 4 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- HAN Biomedical Inc
Vasomotor Symptoms (VMS) Associated With Menopause
An Observational Study to Learn More About Vasomotor Symptoms Burden and Treatment Patterns in Menopausal Women Before and After Participating in OASIS Studies
This is an observational study to learn more about vasomotor symptoms (VSM) burden and treatment patterns in menopausal women before and after participating in OASIS studies.
- Trial name
- OASIS STAR (NCT06949553)
- Testing
- No study intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Menopause
A Comparison of Patch vs. Pill Estrogen Therapy on Testosterone Levels and Thyroid Tests in Menopausal Women
This study compares the effects of 12 weeks of treatment with transdermal versus oral estrogen therapy on testsoterone levels and thyroid tests in healthy, naturally menopausal women.
- Trial name
- NCT00224094
- Testing
- Premarin® (oral) vs. Alora® (transdermal)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Watson Pharmaceuticals
Menopause, Cancer
The Menopause After Cancer Study
This study will recruit women with vasomotor symptoms of menopause and a prior cancer diagnosis, for whom conventional menopausal hormone therapy (MHT) is contraindicated for any reason.
- Conditions
- Menopause, Cancer, Insomnia
- Trial name
- MACS (NCT04766229)
- Testing
- Citalopram +/- Gabapentin + Sleepio + support person
- Where
- 2 sites in Ireland
- Volunteers
- 205 people
- Sponsor
- University College Dublin
Menopause
Estrogen and the Urogenital Microbiome in GSM
This is a study of how local estrogen treatment affects the microbiome of the vagina and bladder in postmenopausal women experiencing symptoms as part of "Genitourinary Syndrome of Menopause." The goal is to understand more about…
- Trial name
- NCT03336437
- Testing
- Estradiol vaginal ring
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Menopause, Cognitive Change
PhytoSERM to Prevent Menopause Associated Decline in Brain Metabolism and Cognition
This is a proof-of-concept phase 2 clinical trial to investigate the safety and effect of the phytoestrogenic supplement PhytoSERM on regional brain metabolism by fluorine-18 fluorodeoxyglucose positron emission tomography…
- Conditions
- Menopause, Cognitive Change, Brain Disorder, Metabolic
- Trial name
- NCT05664477
- Testing
- PhytoSERM
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Roberta Brinton
Postmenopause, Hot Flashes
Effects of Black Cohosh on Menopausal Hot Flashes
This study will assess whether treatment with black cohosh is effective in reducing the frequency and intensity of menopausal hot flashes.
- Conditions
- Postmenopause, Hot Flashes, Osteoporosis, Postmenopausal
- Trial name
- NCT00010712
- Testing
- Black Cohosh
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Menopausal and Perimenopausal Disorder, Unspecified, Atrophic Vaginitis
Preliminary Study of a Vaginal Lubrication Ring to Treat the Symptoms of Vaginal Dryness
This is a pilot study, assessing the ability and safety of the use of VR101 intravaginal ring to relieve the symptoms of vaginal dryness, in peri and post-menopausal women. VR1010 is designed to release glycerol.
- Trial name
- NCT02029053
- Testing
- Vaginal Lubrication Ring for Vaginal Dryness
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- J3 Bioscience, Inc.
Menopausal Women
A Clinical Trial to Investigate the Effect of Pollen Extracts on Menopausal Symptoms in Healthy Women.
The goal of this study is to investigate the effect of pollen extracts on menopausal symptoms in healthy women The main question it aims to answer is: What is the difference in change in severity of menopausal symptoms as…
- Trial name
- NCT06889753
- Testing
- Graminex WSPE, Graminex LSPE
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Graminex LLC
Sperm DNA Fragmentation
HMG Treatment Reduces Sperm DNA Fragmentation
Male factors account for approximately 50% of infertility cases. The principal etiologies of male infertility include sexual dysfunction, semen abnormalities arising from various etiologies, and idiopathic infertility.
- Trial name
- NCT07873502
- Testing
- Human Menopausal Gonadotropin (hMG), Vitamin E
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Jinling Hospital, China
Induced Menopause
Nurse-Led Self-Compassion Intervention for Women With Induced Menopause
This study evaluated the effectiveness of a nurse-led self-compassion intervention on self-compassion, menopausal symptom severity, and self-esteem among women with medically induced menopause.
- Trial name
- NCT07884357
- Testing
- Nurse-Led Self-Compassion Intervention
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Aya Ibrahim
Menopause Related Conditions
Low-level Laser Therapy in Genitourinary Symptoms of Menopause
The study will employ a prospective single-arm design involving menopausal women who present with genitourinary symptoms of menopause (GSM).
- Trial name
- NCT06074120
- Testing
- Low-level laser therapy
- Where
- Taiwan
- Volunteers
- 27 people
- Sponsor
- National Taiwan University Hospital
Skin Aging
Menopausal Impact on Skin Aging Among Egyptian Women
The goal of this study is to understand how menopause affects skin aging in Egyptian women between the ages of 40 and 60. The main question the study wants to answer is: Does menopause cause any changes in how the skin ages? To…
- Trial name
- NCT07120542
- Testing
- Dermoscopy
- Volunteers
- 500 people
- Sponsor
- Sohag University
Type 2 Diabetes Mellitus, Menopause
Effect of Anti-diabetic Drugs on Bone Metabolism and Glycemic Variability
This is a Monocentric, Prospective, Randomized, Open-label, Comparative, Phase IV Study, to compare the effects of Vildagliptin and Gliclazide MR on Markers of Bone Remodeling, Bone Mineral Density and Glycemic Variability in…
- Conditions
- Type 2 Diabetes Mellitus, Menopause, Osteoporosis, Osteopenia
- Trial name
- BoneGlyc (NCT01679899)
- Testing
- Vildagliptin, Gliclazide MR
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Centro de Diabetes Curitiba Ltda
Meditation, Health Education
Women's Healthy Aging and Menopause; (WHAM)
The present study will examine whether women at high risk for developing hypertension, i.e., post-menopausal status, at least mild psychological distress, and mildly elevated blood pressure, show improvements in these risk…
- Trial name
- NCT07314827
- Testing
- Transcendental Meditation (TM), Women's Health Education (WHE)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Miami
Menopausal, Dementia
Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk
By age 45, women's lifetime risk of dementia is estimated to be 1 in 5. Two-thirds of people currently living with a dementia diagnosis are women, and-women make up the majority of carers for people with dementia.
- Trial name
- PERI-MIND (NCT06965686)
- Testing
- PERI-MIND
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Chicago
Post-menopausal ER+ Stage I-IIIA Primary Operable Breast Cancer
Anti-Proliferative Effects and Genomic Alterations of Abiraterone Acetate Compared to an Aromatase Inhibitor in Post-menopausal HR+ Operable Breast Cancer
This study is being offered to patients who are post-menopausal, have breast cancer with a positive estrogen and/or progesterone hormone receptor test and are currently awaiting surgery for breast cancer.
- Trial name
- NCT01814865
- Testing
- Abiraterone Acetate, Prednisone, Aromatase Inhibitor
- Where
- 4 sites in Canada
- Sponsor
- British Columbia Cancer Agency
Osteoporosis, Post-Menopausal
Long Term Effects of Raloxifene Treatment on Bone Quality
This is a cross-sectional study to determine, via iliac crest bone biopsies, the effect of long-term treatment with raloxifene on histomorphometry and bone quality in patients who participated in the Continuing Outcomes Relevant…
- Trial name
- NCT00532428
- Testing
- Raloxifene
- Where
- 7 sites in United States, Mexico and 2 more
- Volunteers
- 31 people
- Sponsor
- Eli Lilly and Company
Vasomotor Symptoms
Acupuncture in Menopause
The primary purpose of this study is to determine the effectiveness of acupuncture for treating vasomotor and other symptoms associated with menopause as acupuncture is generally practiced in the "real world" setting and to…
- Trial name
- AIM (NCT01276028)
- Testing
- Acupuncture
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Wake Forest University Health Sciences
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