Clinical trials: Menopause
Menopause Symptoms
The Impact of Concurrent Training on Women Experiencing Symptoms of Menopause
The aim of this study is to examine the impact of a concurrent training exercise intervention on menopausal symptoms and key physical and mental health outcomes.
- Trial name
- NCT07417228
- Testing
- Concurrent training
- Where
- Ireland
- Volunteers
- 90 people
- Sponsor
- University College Dublin
Dyspareunia, Menopause
Genital Laser Treatment in Postmenopausal Patients
Regulation of sexual functions without hormonal support in order to correct the sexual dysfunctions in women with the estrogen hormone lost in the menopausal process.
- Conditions
- Dyspareunia, Menopause, Sexual Activity, Atrophy Vulva
- Trial name
- NCT05631665
- Testing
- Survey results before and after laser treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Menopause Symptoms
Study to Evaluate the Effects of the Cooling Bolero in Women With Common Menopause Symptoms
The Cooling Bolero is a a vest filled with a new material (not ice or a gel) that provides controlled cooling by absorbing heat. The vest is manufactured by Nanohealth.
- Trial name
- NCT02795741
- Testing
- Cooling Bolero
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Englewood Hospital and Medical Center
Menopause, Postmenopausal Vaginal Atrophy
Vagifem® Used for the Treatment of Atrophic Vaginitis Due to Oestrogen Deficiency
This study is conducted in Europe. The aim of this study is to investigate the self-reported impact of Vagifem® (estradiol) treatment on urogenital discomfort in women with atrophic vaginitis due to oestrogen deficiency.
- Trial name
- NCT01507454
- Testing
- estradiol, 25 mcg
- Where
- Germany
- Volunteers
- 1,613 people
- Sponsor
- Novo Nordisk A/S
Climacteric Syndrome, Postmenopausal Symptoms
Multimodal Program for Climacteric Women
Your study seems to aim at emphasizing the significance of non-pharmacological and non-hormonal approaches in managing menopausal symptoms, particularly focusing on muscle training and education.
- Conditions
- Climacteric Syndrome, Postmenopausal Symptoms, Menopause, Perimenopausal Disorder
- Trial name
- NCT06419972
- Testing
- multimodal physiotherapy programme
- Where
- 2 sites in Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Skin Ageing
Evaluation of Soy Isoflavones on Skin Ageing Parameters
This double-blind, placebo-controlled, randomised pilot trial aims to assess the effect of oral soy isoflavone consumption on skin ageing parameters in post-menopausal women.
- Trial name
- ISOSKIN (NCT06047145)
- Testing
- soy isoflavones
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Postmenopausal Osteoporosis
Study of Post Menopausal Osteoporosis (PMO) Among Gynecology Outpatients in Pakistan
This observational study will provide an opportunity to document local patterns of susceptibility, patient profile, and usefulness of screening in postmenopausal patients coming to gynecology outpatient clinics in Pakistan.
- Trial name
- NCT02422069
- Where
- 8 sites in Pakistan
- Volunteers
- 624 people
- Sponsor
- Hoffmann-La Roche
Menopause, Estrogen Deficiency
Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics (NoMEN Study)
This study will evaluate changes in blood vessels around the heart (e.g., aorta and carotid arteries) and in the brain with the loss of female sex hormones (e.g., estrogen) during the menopause transition.
- Conditions
- Menopause, Estrogen Deficiency, Women, Aging
- Trial name
- NCT05057546
- Testing
- GnRH antagonist
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Atrophy, Vaginal Diseases
Efficacy and Safety of Ospemifene in the Treatment of Moderate to Severe Vaginal Dryness and Vaginal Pain Associated With Sexual Activity
The purpose of this study is to determine the safety and efficacy of ospemifene in postmenopausal women experiencing moderate to severe vaginal dryness and vaginal pain associated with sexual activity.
- Trial name
- NCT00729469
- Testing
- Ospemifene 60 mg
- Volunteers
- 919 people
- Sponsor
- Shionogi
Iron-deficiency
Safety and Effectiveness of IHAT in Iron Deficient Pre-menopausal Woman
This is a double blind, randomised, placebo-controlled trial to evaluate orally-dosed IHAT (iron hydroxide adipate tartrate) at 2 different doses compared to placebo for increasing serum ferritin levels in iron-deficient but…
- Trial name
- NCT05950841
- Testing
- Low dose IHAT, High Dose IHAT, Carob flour
- Where
- Australia
- Volunteers
- 180 people
- Sponsor
- RDC Clinical Pty Ltd
Postmenopausal Period
The Effect of High Intensity Functional Exercise Programs on Menopausal Symptoms, Physical Performance, and Dual Task Performance in Postmenopausal Women
This study was conducted to examine the effects of exercise programs on the physical and psychosocial health of postmenopausal women.
- Trial name
- HIFT-PM (NCT07471620)
- Testing
- High-intensity functional exercise, moderate to low intensity exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Pregnancy
Urine Sample Collection From Non Pregnant Peri and Post-menopausal Women
This is a sample collection study, participants will be required to collect one (if last menstrual period ≥12 months) or two (if last menstrual period <12 months) urine samples and return them to the study site, together with…
- Trial name
- NCT02945189
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Breast Cancer
PET/CT Guided Fulvestrant Therapy for Patients With Recurrent or Metastatic Breast Cancer
Purpose: To determine whether [18F]FES can predict clinical benefit (defined as complete response, partial response and stable disease ≥ 6 months) to fulvestrant (250 mg IM q 28 days) in post-menopausal women with recurrent or…
- Trial name
- NCT00816582
- Testing
- Diagnostic Imaging: 18F-FDG PET/CT Scan - Baseline, Diagnostic Imaging: 18F-FES PET/CT - Baseline, Diagnostic Imaging: 18F-FES PET/CT - 3 month follow-up
- Where
- 4 sites in Canada
- Volunteers
- 17 people
- Sponsor
- British Columbia Cancer Agency
Vitamin D Deficiency
The Effect of Vitamin D3 Therapy in Post Menopausal Women and Assessment of Changes in Bone Mineral Density After Orally Vitamin D3 Administration
a study design based on vitamin D deficiency in postmenopausal women with low bone density. pre-test for BMD will be done then vitamin D oral supplements will be provided for the period of 3 months.
- Trial name
- NCT05389943
- Testing
- Oral administration of vitamin D3, Vitamin D3 50000 UNT Oral Capsule, milk, Dietary and life style modifications.
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sargodha
Metabolic Syndrome, Menopause
Effects of L-citrulline Supplementation on Vascular Function in Metabolic Syndrome
The objective of this project is to provide evidence that L-Citrulline (CIT) supplementation can improve vascular function in the fasted and acute hyperglycemia conditions in middle-aged and older women with metabolic syndrome.
- Trial name
- NCT06025357
- Testing
- L-Citrulline supplementation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Menopause, Depression
Impact of Hot Flashes on Sleep and Mood Disturbance
We plan to enroll premenopausal women in a trial investigating the impact of hot flashes developed in response to an injection of a gonadotropin-releasing hormone agonist (GnRHa), leuprolide (brand name: Lupron), on sleep…
- Conditions
- Menopause, Depression, Hot Flashes
- Trial name
- NCT01116401
- Testing
- leuprolide
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Vaginal Atrophy
Exploratory Study on Two Different Doses of VML-0001 on the Effects on Vaginal pH in Healthy Post-Menopausal Women
The study is designed to determine the effect on vaginal pH and the duration of action measured on the ability of the base formulation to reduce the vaginal pH
- Trial name
- NCT03770065
- Testing
- VML-0001
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Viramal Limited
Exercise-induced Joint Pain Stiffness and Cartilage Turnover
NEM® Versus Placebo on Exercise-induced Joint Pain, Stiffness, & Cartilage Turnover In Healthy, Post-Menopausal Women
This study is intended to evaluate the effect of the dietary supplement NEM® brand eggshell membrane versus placebo in reducing exercise-induced joint pain \& stiffness \& cartilage turnover in healthy post-menopausal women.
- Trial name
- NCT02751944
- Testing
- NEM
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ESM Technologies, LLC
Dyslipidemias, Obesity
Time-restricted Eating in Peri- and Postmenopausal Women
The overall objective of the study is to examine the effect of an 8-hour time-restricted eating intervention on lipid levels and body composition in peri- and recently postmenopausal women with untreated dyslipidemia.
- Conditions
- Dyslipidemias, Obesity, Menopause
- Trial name
- NCT06188598
- Testing
- Time-restricted eating
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Coronary Artery Disease, Menopause
The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers
Cardiovascular diseases (CVD) and neoplasms are the main causes of death in Brazilian women. Coronary artery disease (CAD) and stroke were responsible for approximately 54% of deaths from CVD in this population.
- Conditions
- Coronary Artery Disease, Menopause, Endothelial Dysfunction
- Trial name
- RE-AGES (NCT05808387)
- Testing
- Resveratrol
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- InCor Heart Institute
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