Clinical trials: Menopause-Hot Flashes
Menopause
Qing'E Formula Therapy on Menopausal Symptoms
The objective of this study is to evaluate whether a Chinese medicine formula (Qing'E) is effective in alleviating menopausal symptoms and safety.
- Trial name
- NCT01805765
- Testing
- Qing'E pills
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Menopause, Insomnia
Cognitive Behavioral Therapy for Insomnia and Nocturnal Hot Flashes in Menopause
The primary aim of the current study is to evaluate the effectiveness of a Cognitive Behavioral Therapy intervention in the treatment of menopause-associated insomnia and nocturnal hot flashes.
- Conditions
- Menopause, Insomnia, Hot Flashes
- Trial name
- NCT02092844
- Testing
- CBT for Menopausal Insomnia (CBTMI)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Breast Cancer, Menopausal Symptoms
Effect of a Brassicaceae-Enriched Diet on Menopausal Symptoms in Women With Breast Cancer Receiving Antiestrogen Therapy
This study aims to evaluate whether increasing the intake of Brassicaceae vegetables may help reduce menopausal symptoms in women with hormone-sensitive breast cancer who are receiving adjuvant antiestrogen therapy.
- Trial name
- BRASSICA (NCT07842614)
- Testing
- Increased Dietary Intake of Brassicaceae Vegetables
- Where
- Italy
- Volunteers
- 81 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Menopause Hot Flashes
Fezolinetant and Vascular Health and Brain Health
The goal of this clinical trial is to learn whether a study drug called fezolinetant impacts cardiovascular and cognitive health in women who have moderate to severe menopausal hot flashes and night sweats.
- Trial name
- FAVES-B (NCT07606664)
- Testing
- Fezolinetant
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Rebecca Thurston
Menopause, Hot Flashes
Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW)
This study will evaluate whether an 8-week course of a standardized herbal extract containing Shatavari and natural bio-enhancer ingredients can reduce menopausal symptoms in post-menopausal women.
- Trial name
- RENEW (NCT07834463)
- Testing
- Shatavari (Asparagus racemosus) Extract
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- India Glycols Ltd
Hot Flashes, Menopause
MsFLASH-01: Escitalopram for Menopausal Symptoms in Midlife Women
The purpose of this study is to test whether a medication reduces the number, severity and bothersomeness of menopausal hot flashes. Escitalopram (also called Lexapro®) is a selective serotonin reuptake inhibitor (SSRI).
- Conditions
- Hot Flashes, Menopause, Vasomotor Symptoms
- Trial name
- NCT00894543
- Testing
- Escitalopram
- Where
- 5 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Hot Flashes, Menopause
Comparison of the Effect of Exercises on Vasomotor Symptoms in Middle Aged Women
Vasomotor symptoms (VMS) develop in the premenopausal period and symptoms may persist for years after menopause.Vasomotor symptoms such as hot flashes, night sweats, mood swings and sleep disturbances affect women's quality of…
- Trial name
- NCT05892094
- Testing
- Resistance and Aerobic Training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul Medipol University Hospital
Vasomotor Symptoms, Hot Flushes
Dehydroepiandrosterone (DHEA) + Acolbifene Against Vasomotor Symptoms (Hot Flushes) in Postmenopausal Women
The purpose of this Phase III trial is to evaluate the efficacy of oral administration of dehydroepiandrosterone (DHEA) combined with acolbifene (a selective estrogen receptor modulator (SERM)) on vasomotor symptoms (hot flushes)…
- Trial name
- NCT01452373
- Testing
- DHEA and Acolbifene
- Where
- 15 sites in Canada
- Volunteers
- 238 people
- Sponsor
- EndoCeutics Inc.
Menopause, Hot Flashes
A Dose-ranging Study of the Efficacy of ESN364 in Postmenopausal Women Suffering Vasomotor Symptoms (Hot Flashes)
This study determined the effects of different doses and dosing regimens of ESN364 on the frequency and severity of hot flashes.
- Trial name
- NCT03192176
- Testing
- Fezolinetant
- Where
- 51 sites in United States
- Volunteers
- 356 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Hot Flashes
A Study to Find Out if Fezolinetant Helps Reduce Moderate to Severe Hot Flashes in Women Going Through Menopause
This study was for women in menopause with moderate to severe hot flashes. Menopause, a normal part of aging, is the time of a woman's last period. Hot flashes can interrupt a woman's daily life.
- Trial name
- Skylight 1 (NCT04003155)
- Testing
- fezolinetant
- Where
- 96 sites in United States, Canada and 5 more
- Volunteers
- 527 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Hot Flashes
Mechanical Device for the Relief of Hot Flashes
Hypothesis: A mechanical device when applied to the back of the neck at the onset of a menopausal hot flash will attenuate the severity and duration of symptoms providing women with a reassuring non-hormonal intervention to…
- Trial name
- NCT01281332
- Testing
- Menopod, Inactive device
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Queen's University
Menopause, Hot Flashes
PhytoSERM for Menopausal Hot Flashes and Sustained Brain Health
This is a proof-of-concept phase 2 clinical trial to investigate the effect of the phytoestrogenic supplement PhytoSERM on vasomotor symptoms and other symptoms associated with the menopausal transition, and on blood-based…
- Trial name
- HF-Relief (NCT06186531)
- Testing
- PhytoSERM
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- NeuTherapeutics
Obesity, Menopause Hot Flashes
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity
The purpose of this study is to determine the effect of tirzepatide on vasomotor symptoms and on measures of biological aging.
- Trial name
- NCT07218445
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Menopause
Studying the Impact of Exercise on Hot Flashes
A prospective randomized pragmatic trial will be used to obtain data on energy expenditure, temperature changes and vasomotor symptoms at baseline, during the intervention in which participants will be randomized to either…
- Trial name
- NCT03236896
- Testing
- Exercise, No exercise
- Volunteers
- 35 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Menopause, Hot Flashes
Caria: Digital Intervention for Menopause Symptom
Menopause is the time of life when menstrual cycles cease. Women typically spend 30-40% of their lives in menopause. Individual experiences of menopause vary and although some women do not experience any significant symptoms…
- Trial name
- NCT04882982
- Testing
- Caria app, Menopause Education
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Illinois at Chicago
Menopause, Hot Flashes
Alternative Therapies for Menopause: A Randomized Trial
This randomized, controlled trial will evaluate the efficacy and safety of three alternative approaches utilizing phytoestrogens to treat hot flashes and night sweats in peri- and post-menopausal women.
- Trial name
- NCT00061711
- Testing
- Hormone Replacement Therapy, Cimicifuga racemosa (Black Cohosh), Multibotanical phytoestrogen formula
- Where
- United States
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Menopausal Symptoms
Effects of Soy Isoflavones on Menopausal Hot Flashes
Hot flashes occur in three quarters of menopausal women, and can negatively impact quality of life. Interest has arisen in isoflavones, found in rich supply in soy products, as therapy for hot flashes.
- Trial name
- NCT00179556
- Testing
- Isoflavone supplement
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Hot Flashes
24-Week Efficacy & Safety Study of Brisdelle™ (Formerly Known as Mesafem) in the Treatment of Vasomotor Symptoms
To assess the safety and efficacy of Brisdelle (paroxetine mesylate) Capsules 7.5 mg for treatment of vasomotor symptoms (VMS) associated with menopause
- Trial name
- NCT01101841
- Testing
- Brisdelle (paroxetine mesylate)
- Where
- 32 sites in United States
- Volunteers
- 570 people
- Sponsor
- Noven Therapeutics
Menopause-related Hot Flashes
Yoga for Treatment of Hot Flashes
The Yoga for Treatment of Hot Flashes and Menopausal Symptoms is an uncontrolled pilot clinical trial to determine the feasibility of recruitment and of evaluating yoga for the relief of menopausal hot flashes in 12 peri- or…
- Trial name
- NCT00283205
- Testing
- Yoga
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Menopausal Symptom Relief
"Pi" and Hot Flushes
Hot flushes are common symptoms in women after menopause, and are important causes of discomfort and lead to high number of medical consultations.
- Trial name
- NCT01315041
- Testing
- Capsicum frutescens fruits, homeopathic medicine, Inert alcoholic solution
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Casa Espirita Terra de Ismael