Clinical trials: Menstrual Cramp
Endometriosis
Endometriosis Trial: Study of NBI-56418 in Endometriosis
This is a Phase II, multicenter, randomized, double-blind, placebo-controlled, parallel-group study with subjects randomized to one of three treatment groups, placebo, 75 mg and 150 mg in a 1:1:1 ratio.
- Trial name
- NCT00109512
- Testing
- NBI-56418 (GnRH antagonist)
- Where
- 15 sites in United States
- Volunteers
- 76 people
- Sponsor
- Abbott
Menorrhagia, Dysmenorrhea
Prospective, Non-interventional, Multi-center Safety Study of Mirena for Heavy Menstrual Bleeding and Dysmenorrhea
The primary objective in this study is collecting post-marketing information on the safety. Thus, it includes information under the routine clinical practice on adverse events (AEs) and adverse drug reactions (ADRs) including…
- Trial name
- J-MIRAI (NCT02475356)
- Testing
- Levonorgestrel IUS (Mirena, BAY86-5028)
- Where
- Japan
- Volunteers
- 601 people
- Sponsor
- Bayer
Primary Dysmenorrhea (PD)
Muscle Energy Technique and Myofascial Chain Training for Menstrual Pain in Primary Dysmenorrhea (METPD-25)
This prospective clinical trial evaluates the effects of a non-pharmacological intervention combining muscle energy technique (MET) and myofascial chain (MFC)-based pelvic stabilization training in women with primary dysmenorrhea…
- Trial name
- METPD-25 (NCT07058480)
- Testing
- Combined MET and MFC-Based Pelvic Stabilization Training, Interferential current therapy (ICT), Deep Friction Massage (DFM)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanjiao Luo
Dysmenorrhea
Study to Assess the Safety and Efficacy of Etoricoxib Versus Ibuprofen in the Treatment of Dysmenorrhea (MK-0663-145 AM1)
This is a study to determine the overall analgesic effect of a single oral dose of etoricoxib compared to ibuprofen in participants with moderate-to-severe primary dysmenorrhea.
- Trial name
- NCT01462370
- Testing
- Etoricoxib, Ibuprofen, Acetaminophen 250 mg, isopropylantipyrine 150 mg and anhydrous caffeine 50 mg
- Volunteers
- 139 people
- Sponsor
- Organon and Co
Primary Dysmenorrhea, Pain
More Than Just p-Values: MCID for the VAS, MSQ and FEMD in Patients With Primary Dysmenorrhea
The aim of this study is to determine the Minimal Clinically Important Difference (MCID) for the Visual Analog Scale (VAS), Menstrual Symptom Questionnaire (MSQ), and Functional and Emotional Measure of Dysmenorrhea (FEMD) in…
- Conditions
- Primary Dysmenorrhea, Pain, Menstrual Discomfort
- Trial name
- NCT06835036
- Testing
- Exercise Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Artvin Coruh University
Primary Dysmenorrhea
Effects of Functional Exercise Versus High Frequency Transcutaneous Electrical Nerve Stimulation on Primary Dysmenorrhea
The objective of this study is to assess the impacts of utilitarian exercise versus high frequency anscutaneous Electrical Nerve Stimulation on pain and sleep quality in students with primary dysmenorrhea.
- Trial name
- NCT05439096
- Testing
- Functional Exercise, High Frequency Transcutaneous Electrical Nerve Stimulation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Infertility, Female
Effects of Wurn Technique on Dyspareunia, Menstrual Cramps & QoL in Infertile Women
Wurn technique is a PT technique. It is site specific massage therapy in the form of relaxing technique, helps to promote the function of abdominopelvic and reproductive organs.
- Trial name
- NCT06845670
- Testing
- Wurn technique
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Primary Dysmenorrhea
Primary Dysmenorrhea and Comfort Theory
Dysmenorrhea is defined as lower abdominal pain experienced during menstruation. It is divided into two types: primary dysmenorrhea and secondary dysmenorrhea.
- Trial name
- NCT07376759
- Testing
- Comfort Theory-Based Education
- Volunteers
- 80 people
- Sponsor
- Ordu University
Dysmenorrhea, Endometriosis
Effect of Melatonin on Reduction of Pelvic Pain
In two double blinded randomized controlled trials (RCT) we will study the effect of pain reduction of melatonin vs placebo in women with severe dysmenorrhea and women with endometriosis.The aim is to find an effective method for…
- Trial name
- NCT03782740
- Testing
- Melatonin 10 mg, Melatonin 20 mg
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Dysmenorrhea, Inflammation
The Effects of Exercise and Probiotics on Dysmenorrhea and Microbiome
The study try to investigate the possible effects of exercise and probiotics supplementation on dysmenorrhea amelioration from the perspective of microbiome.
- Conditions
- Dysmenorrhea, Inflammation, Microbial Substitution
- Trial name
- NCT05326217
- Testing
- Aerobic exercise, Resistant exercise
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Adenomyosis, Adenomyoma of Uterus
Ultrasound-Guided Radiofrequency Ablation for Focal Adenomyosis
This single-center, single-arm, open-label study evaluates the efficacy and safety of ultrasound-guided radiofrequency ablation (RFA) in women with symptomatic focal adenomyosis who wish to preserve the uterus.
- Trial name
- RFA-ADENO-USG (NCT07906535)
- Testing
- Myoblate Radiofrequency Ablation System (Mygen V-1000 generator)
- Where
- Czechia
- Volunteers
- 41 people
- Sponsor
- University Hospital Pilsen
Primary Dysmenorrhea
The Effects Of Pilates-Based Tele-Exercise In Primary Dysmenorrhea
In this study, the investigators will aim to investigate the effects of Pilates-based tele-exercise on the physical and mental health of women with primary dysmenorrhea.
- Trial name
- NCT06518525
- Testing
- pilates-based tele-exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Derya Azim
Dysmenorrhea, Metrorrhagia
Cooperative Adenomyosis Network
To set up a Cooperative Network by enrolling 5000 patients with Adenomyosis(AM) from multiple centers.Based on the Network platform and Database,the investigators try to explore the diagnostic strategies for AM and carry out…
- Conditions
- Dysmenorrhea, Metrorrhagia, Infertility, Female, Pathology
- Trial name
- CAN (NCT03230994)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Peking Union Medical College Hospital
Primary Dysmenorrhea, Dysmucorrhea
Effects of High-frequency Deep Diathermy on Heart Rate Variability in Women With Primary Dysmenorrhea
Superficial heat therapy is mainly used to relieve menstrual pain, but it does not penetrate deeper than the skin tissue. In order to penetrate deep into the deep layers and promote tissue relaxation, deep heat therapy can be…
- Trial name
- NCT04937270
- Testing
- High frequency therapy (5 minutes), High frequency therapy (7 minutes), High frequency therapy (9 minutes)
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Sahmyook University
Primary Dysmenorrhea (PD)
Graded Motor Imagery for Primary Dysmenorrhea
The goal of this clinical trial is to learn if graded motor imagery can reduce pain sensitivity and period pain in women with primary dysmenorrhea (painful periods with no medical cause).
- Trial name
- NCT07618832
- Testing
- Graded Motor Imagery (GMI)
- Where
- Pakistan
- Volunteers
- 81 people
- Sponsor
- Dr. Mehak Naeem
Endometriosis
Effects of Aerobic Exercise and Core Muscle Strengthening on Pain, Menstrual Pattern and QOL in Endometriosis
Endometriosis is a complex and debilitating gynecological condition affecting millions of women worldwide. It is characterized by the abnormal growth of endometrial-like tissue outside the uterus, leading to chronic pelvic pain…
- Trial name
- NCT06241040
- Testing
- Aerobic Exercises with core Muscle strengthening, Aerobic Exercise without Core Muscle Strengthening
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Menstrual Pain
Effectiveness of PEA Compared to Placebo on Acute Menstrual Pain
This is a double blind, randomised, placebo-controlled trial to evaluate orally-dosed Palmitoylethanolamide (PEA) compared to placebo on menstrual pain in otherwise healthy participants 18 years and over.
- Trial name
- NCT05810116
- Testing
- Levagen+, Microcrystalline cellulose
- Where
- Australia
- Volunteers
- 80 people
- Sponsor
- RDC Clinical Pty Ltd
Dysmenorrhea Primary, Pain Management
The Effect of Breathing-based Pelvic Floor Muscle Training on Menstrual Symptoms, Pain and Quality of Life
Primary dysmenorrheic (PD) pain usually begins during adolescence, at menarche or shortly after (6-24 months), and has a clear and predictable temporal pattern.
- Conditions
- Dysmenorrhea Primary, Pain Management, Diaphragmatic Breathing, Pelvic Floor Muscle Exercise
- Trial name
- NCT06615258
- Testing
- Dynamic Neuromuscular Stabilization based breathing training and pelvic floor muscle training, Pelvic floor muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Izmir University of Economics
Dysmenorrhea, Menstrual Pain
Non-Steroidal Anti-Inflammatory Drug (NSAID) Response and Central Sensitization of Pain in Women With Dysmenorrhea
Menstrual pain is the most common gynecological complaint and the leading cause of school and work absences in reproductive-age girls and women.
- Conditions
- Dysmenorrhea, Menstrual Pain, Non-steroidal Anti-inflammatory Drug
- Trial name
- NCT05900336
- Testing
- Sodium Naproxen
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Dysmenorrhea, Exercise
Kinesiotaping Versus Pilate Exercises
Sixty girls participated in this study and their main complaints were pain and cramping during menstruation. They were divided randomly into two equal groups.
- Trial name
- NCT04359381
- Testing
- kinesiotaping application, Pilate exercises program
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University