Clinical trials: Menstrual Cramp
Primary Dysmenorrhea
Effect of MA Versus TENS for Primary Dysmenorrhea
The trial aims to evaluate the effect of manual acupuncture versus transcutaneous electric nerve stimulation in treating primary dysmenorrhea.
- Trial name
- NCT03977519
- Testing
- MA, TENS
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Dysmenorrhea
A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Pain
This study is being conducted to evaluate the effects of treatment with Seasonique an extended-regimen oral contraceptive that utilizes low dose ethinyl estradiol during the typical hormone-free interval.
- Trial name
- NCT00196365
- Testing
- levonorgestrel/EE 0.15/0.03 and EE 0.01 mg tablets
- Where
- 18 sites in United States
- Volunteers
- 97 people
- Sponsor
- Duramed Research
Kinesio Taping, Myofascial Release Technique
Comparison of Acute Effects of Myofascial Release and Kinesio Taping® in Dysmenorrhea
Dysmenorrhea is a physiological condition and one of the most common issues experienced during menstruation. This study aims to compare the acute effects of Myofascial Release Technique (MRT) and Kinesio Taping® (KT) on pain…
- Conditions
- Kinesio Taping, Myofascial Release Technique, Pain, Primary Dysmenorrhea (PD)
- Trial name
- Dysmenorrhea (NCT06925087)
- Testing
- Myofascial Release Technique, Kinesio Taping Technique
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cyprus International University
Primary Dysmenorrhea
Rhythmical Massage Compared With Heart Rate Variability Biofeedback in Women With Menstrual Pain (Dysmenorrhea)
A study to explore whether rhythmical massage and heart rate variability biofeedback can help to reduce pain in women suffering from menstrual pain (dysmenorrhea).
- Trial name
- NCT03712800
- Testing
- Rhythmical massage, HRV biofeedback
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Dysmenorrhea Primary
A Study of Diclofenac Gel in Women With Primary Dysmenorrhea
The goal of this clinical trial is to compare 1% and 3% diclofenac gel (DARE-PDM1) to placebo in women with symptomatic primary dysmenorrhea.
- Trial name
- DARE-PDM1 (NCT05752526)
- Testing
- Diclofenac 1%, Diclofenac 3%
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Daré Bioscience, Inc.
Dysmenorrhea, Nonpharmalogical Pain Management
Anastatica Hierochuntica Breathing Exercises Dysmenorrhea
This randomized controlled trial was conducted between June 12 and December 29, 2025, among female university students to evaluate the effects of Anastatica hierochuntica application and breathing exercises on functional and…
- Trial name
- NCT07481552
- Testing
- Anastatica hierochuntica, Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Primary Dysmenorrhea
Tele-Pilates for Primary Dysmenorrhea
This randomized controlled trial investigates the effectiveness of a synchronized tele-Pilates program on menstrual pain, symptom severity, physical disability, and trunk muscle endurance in women with primary dysmenorrhea (PD).
- Trial name
- NCT07335926
- Testing
- Tele-Pilates Exercise program, standardized menstrual health education online
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Atlas University
Period Pain
Impacts of Static Magnetic Fields on Dysmenorrhea Pain
Study to determine the effectiveness of a certain type of magnet to reduce period pain
- Trial name
- NCT04539691
- Testing
- Magnet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Endometriosis
Postoperative Desogestrel for Endometriosis Related Pain
Endometriosis is one of the most common disease in reproductive aged women.Surgical intervention has a significant symptoms relief. However, symptom recurrence is often after surgery.
- Trial name
- NCT01559480
- Testing
- Desogestrel
- Where
- 2 sites in Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Endometriosis
Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain (EDELWEISS 6)
The primary objective of this extension study is to assess the maintenance of efficacy of linzagolix administered orally once daily for up to an additional 6 months (for up to 12 months of treatment in total) in women who have…
- Trial name
- NCT04335591
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 47 sites in United States, Austria and 7 more
- Volunteers
- 356 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Primary Dysmenorrhea
Menstrual Health Education's Impact on Knowledge, Attitudes and Self Care Behavior of Dysmenorrheal Adolescents
This study will be a randomized controlled trial. This study will be conducted in F G modal for girls' I/8-4, Federal Government College for Women and Islamabad Model College for Girls.
- Trial name
- NCT05315050
- Testing
- Educational session and Information Pamphlet, Information Pamphlet
- Where
- Pakistan
- Volunteers
- 138 people
- Sponsor
- Riphah International University
Endometriosis
A Global Phase 3 Study to Evaluate the Safety and Efficacy of Elagolix in Subjects With Moderate to Severe Endometriosis-Associated Pain
A randomized study evaluating the safety and efficacy of elagolix in the management of moderate to severe endometriosis-associated pain in adult premenopausal female subjects.
- Trial name
- ELARIS EM-II (NCT01931670)
- Testing
- Elagolix
- Volunteers
- 815 people
- Sponsor
- AbbVie
Autoimmune Diseases
Effect of Transcutaneous Electrical Acupoint Stimulation on Dysmenorrhea Among Autoimmune Disease Women
This study will be conducted to investigate transcutaneous electrical acupoint stimulation effect on pain and disease aggravation during menstruation among autoimmune disease women
- Trial name
- NCT06976151
- Testing
- Non-steroidal anti-inflammatory drugs (NSAID), Transcutaneous Electrical Acupoint Stimulation (TEAS)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Primary Dysmenorrhea, Kinesics
Kinesiological Taping and Aerobic Exercise in Women With Primary Dysmenorrhea:
Dysmenorrhea is defined as the pain and discomfort of women during the menstrual period. Kinesiological taping (KT) and aerobic exercise (AE) are effective methods for dysmenorrhea.
- Conditions
- Primary Dysmenorrhea, Kinesics, Aerobic Exercise
- Trial name
- NCT04856280
- Testing
- Kinesiological taping, Aerobic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Trigger Point Pain, Myofascial, Acupuncture
Clinical Study on Dry Needling for Primary Dysmenorrhea and Its Preliminary Correlation With Acupoints
Primary dysmenorrhea refers to menstrual pain not caused by pelvic organic lesions, commonly seen in young women, significantly affecting patients' quality of life.
- Conditions
- Trigger Point Pain, Myofascial, Acupuncture, Primary Dysmenorrhea
- Trial name
- NCT06316583
- Testing
- TrP-DN and Acupuncture
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- Beijing Hospital
Dysmenorrhea
Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Dysmenorrhea
The purpose of this study is to determine whether combination oral contraceptive pill of Norethindrone \& Ethinyl estradiol is effective in the treatment of dysmenorrhea associated with endometriosis.
- Trial name
- NCT00212342
- Testing
- Norethisterone,Ethinylestradiol, Sugar pill
- Volunteers
- 100 people
- Sponsor
- Nobelpharma
Premenstrual Syndrome, Premenstrual Dysphoric Disorder
CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life
This study evaluates the feasibility and efficacy of the Samphire Guided Care (SGC) program a 12-week structured digital health program combining clinician-led onboarding, at-home neuromodulation using the Lutea tDCS device…
- Conditions
- Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Dysmenorrhea, Endometriosis
- Trial name
- CREST (NCT07679074)
- Testing
- Lutea Transcranial Direct Current Stimulation (tDCS) Device, Samphire Guided Care Program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samphire Group, Inc.