Clinical trials: Menstrual Cramps
Dysmenorrhea
Dose-Finding Study of PDC31 in Patients With Primary Dysmenorrhea
The purpose of this study is to determine a safe and effective dose range for intravenous administration (infusion) of PDC31 by determining the maximum tolerated dose of PDC31 in patients with primary dysmenorrhea.
- Trial name
- NCT01250587
- Testing
- PDC31
- Where
- 4 sites in Austria, Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- PDC Biotech GmbH
Dysmenorrhea, Gynecologic Disease
MOPEXE and RE in Treating Dysmenorrhea
The aim of this study is to compare the effects of motor imagery focused pelvic floor exercises and relaxation exercises used in the treatment of dysmenorrhea on pain and menstrual symptoms.
- Trial name
- NCT06011928
- Testing
- MOPEX Exercise, Relaxation Exercise, Combine Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uskudar University
Endometriosis
A Study to Assess the Efficacy and Safety of OBE2109 in Subjects With Endometriosis
The primary objective of this study is to assess the efficacy and safety of a range of oral doses of OBE2109 versus placebo, in reducing endometriosis associated pain.
- Trial name
- EDELWEISS (NCT02778399)
- Testing
- OBE2109
- Where
- 86 sites in United States, Poland and 2 more
- Volunteers
- 328 people
- Sponsor
- ObsEva SA
Dysmenorrhea, Endometriosis
Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With Dysmenorrhea
Dysmenorrhea affects up to 90% of women of reproductive age and represents a significant public health concern. Beyond prostaglandin-mediated uterine contractions, dysmenorrhea involves central sensitization mechanisms and…
- Trial name
- NCT07645196
- Testing
- Abdominal manual mobilization
- Where
- 2 sites in Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Dysmenorrhea
Comparison of Dexketoprofen, Paracetamol and Ibuprofen in the Treatment of Primary Dysmenorrhea
Our study will be performed on 300 patients who meet the criteria for joining the emergency service with primary dysmenorrhea. 3 drugs we will use: 1000 mg vial of paracetamol, dexketoprofen trometamol will be 50 mg ampoule and…
- Trial name
- NCT03697746
- Testing
- paracetamol, Dexketoprofen Trometamol, Ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Endometriosis, Pelvic Pain Syndrome
Study on the Outcomes of Patients Treated in Gynecological Emergency Departments for Pelvic Endometriosis or Suspected Pelvic Endometriosis
Adult patients consulting the gynecological emergency department of CHI Créteil during the inclusion period for endometriosis or symptoms suggestive of endometriosis
- Conditions
- Endometriosis, Pelvic Pain Syndrome, Chronic Gynaecological Disease
- Trial name
- NCT07472842
- Testing
- Emergency care for endometriosis
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Adenomyosis of Uterus, Uterine Diseases
Multicenter Observational Cohort Study on the Epidemiology of Therapeutic Strategies in Patients Affected by Adenomyosis
The primary objective of this multicenter observational cohort study is to evaluate the current medical approach to the management of adenomyosis in women, with particular focus on treatment selection and treatment persistence.
- Conditions
- Adenomyosis of Uterus, Uterine Diseases, Gynecologic Diseases, Menorrhagia, Dysmenorrhea
- Trial name
- Adenomyosis (NCT07478614)
- Testing
- This is a non-interventional study. Treatment allocation will not be influenced by the study protocol.
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- SCHETTINI SERGIO
Primary Dysmenorrhea
Comparison of the Effects of Different Massage Techniques in Women With Primary Dysmenorrhea
The aim of this study was to compare the effects of different massage techniques on pain, primary dysmenorrhea (PD)-related symptoms and functional and emotional influence in women with PD.
- Trial name
- NCT05158036
- Testing
- Classic massage group, Connective tissue masage
- Volunteers
- 50 people
- Sponsor
- Ataturk Training and Research Hospital
Dysmenorrhea Primary
The The Effect of Planned Behavior Theory-Based Education on Physical Activity and Dysmenorrhea
The aim of the study is to examine the effect of the planned behavior theory-based education program applied to university students with primary dysmenorrhea on physical activity behavior and dysmenorrhea's impact.
- Trial name
- NCT06210659
- Testing
- Theory of Planned Behavior Based Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ankara University
Dysmenorrhea Primary, Central Sensitisation
Myofascial Release Technique in Women With Primary Dysmenorrhea
It has been found that women with dysmenorrhea have active trigger points, particularly in the rectus abdominis, oblique abdominal muscles, quadratus lumborum, and paraspinal muscles.
- Conditions
- Dysmenorrhea Primary, Central Sensitisation, Myofascial Trigger Point Pain, Menstrual Discomfort
- Trial name
- NCT06492148
- Testing
- Myofascial Release
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Endometriosis
Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain (EDELWEISS 6)
The primary objective of this extension study is to assess the maintenance of efficacy of linzagolix administered orally once daily for up to an additional 6 months (for up to 12 months of treatment in total) in women who have…
- Trial name
- NCT04335591
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 47 sites in United States, Austria and 7 more
- Volunteers
- 356 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Primary Dysmenorrhea
Effects of Chamomile With L-theanine Beverage Among Young Women Experiencing Primary Dysmenorrhea
This study aims to evaluate the effects of a beverage containing chamomile and L-theanine on menstrual symptoms, pain intensity, mood, and sleep quality among young adult females with primary dysmenorrhea.
- Trial name
- NCT07092878
- Testing
- Chamomile (Matricaria recutita), Chamomile
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Tunku Abdul Rahman
Primary Dysmenorrhea (PD)
Effects of Transcutaneous Tibial and Auricular Vagus Nerve Stimulation in Females With Primary Dysmenorrhea
Primary dysmenorrhea is a common gynecological condition characterized by painful menstrual cramps that can negatively affect daily activities and quality of life.
- Trial name
- NCT07834658
- Testing
- Transcutaneous Tibial Nerve Stimulation (TTNS), Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS), TTNS+TaVNS
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Dysmenorrhea
Impact of OMT on the Symptoms of Dysmenorrhea
This pilot study will span two months per participant and include a baseline evaluation, a control period, the treatment itself, and an after-treatment evaluation.
- Trial name
- NCT07849140
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Western University of Health Sciences
Primary Dysmenorrhea
Menstrual Health Education's Impact on Knowledge, Attitudes and Self Care Behavior of Dysmenorrheal Adolescents
This study will be a randomized controlled trial. This study will be conducted in F G modal for girls' I/8-4, Federal Government College for Women and Islamabad Model College for Girls.
- Trial name
- NCT05315050
- Testing
- Educational session and Information Pamphlet, Information Pamphlet
- Where
- Pakistan
- Volunteers
- 138 people
- Sponsor
- Riphah International University
Dysmenorrhea
The Effect of Psychoeducation on Dysmenorrhea in Nursing Students
This study will be conducted to examine the effect of psychoeducation based on Leventhal's Self-Regulation Model on dysmenorrhea in nursing students.
- Trial name
- NCT05646238
- Testing
- psychoeducation, training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Gazi University
Dysmenorrhea
Chinese Herbal Medicine for Gynecologic Patients
This is a prospective randomized-controlled trial looking at the safety and acceptability of using Chinese herbal medicine in patients with primary dysmenorrhea.
- Trial name
- NCT06187376
- Testing
- Chinese Herbal Medicine (CHM) supplement
- Where
- United States
- Sponsor
- Icahn School of Medicine at Mount Sinai