Clinical trials: Menstrual Cramps
Primary Dysmenorrhea
The Efficacy of Ayurved Siriraj Prasaplai for Treatment Primary Dysmenorrhea
Ayurved Siriraj Prasaplai is a Thai traditional herbal drug for pain treatment. Mostly it was used for antipain during menstruation or dysmenorrhea.
- Trial name
- NCT01598012
- Testing
- Ayurved Siriraj Prasaplai with or without mefenamic acid
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Primary Dysmenorrhea
Impact of Primary Dysmenorrhea on Academic Performance and Quality of Life Among Medical Students at Sohag University
Pain is an unpleasant sensation that negatively affects individual experiencing it, depending on its quality, intensity, location, and duration. One of the causes of pain among females is dysmenorrhea.
- Trial name
- NCT07350902
- Testing
- self administered questionnaire
- Where
- Egypt
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Sohag University
Dysmenorrhea, Pain
The Effect of Distraction Techniques Used in Intramuscular (IM) Injections on Pain in Adolescents Presenting to the Emergency Department With Dysmenorrhea: A Randomized Controlled Study
Brief Summary: This study investigates the effectiveness of non-pharmacological techniques for managing dysmenorrhea (menstrual pain) in adolescents.
- Conditions
- Dysmenorrhea, Pain, Distraction Methods
- Trial name
- "HSTT-SB Dysme (NCT06842329)
- Testing
- Halfer Skin Tape Technique, ShotBlocker Technique, Standard Intramusculer injection
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Duygu MEZDE
Endometriosis Related Pain
SPIRIT 2: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain
The purpose of this study is to determine the benefit and safety of relugolix 40 milligrams (mg) once daily, co-administered with low-dose estradiol (E2) and norethindrone acetate (NETA) compared with placebo for 24 weeks, on…
- Trial name
- NCT03204331
- Testing
- Relugolix, Estradiol/norethindrone acetate
- Where
- 91 sites in United States, Australia and 9 more
- Volunteers
- 623 people
- Sponsor
- Myovant Sciences GmbH
Primary Dysmenorrhea, Menstrual Pain
TENS for Primary Dysmenorrhea
Primary dysmenorrhea is a common gynecological condition characterized by recurrent menstrual pain in the absence of pelvic pathology.
- Conditions
- Primary Dysmenorrhea, Menstrual Pain, Dysmenorrhea
- Trial name
- TENS-DYS (NCT07521553)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Centro Universitario La Salle
Endometriosis, Endometriosis and Dysmenorrhea
Brain and Blood Vessel Health Following Endometriosis Treatment in People With Endometriosis
This research study wants to understand how medications used to treatment symptoms of endometriosis impact brain health in patients with endometriosis.
- Conditions
- Endometriosis, Endometriosis and Dysmenorrhea, Endometriosis (Diagnosis)
- Trial name
- BLOOM (NCT07799246)
- Testing
- Investigate how norethindrone acetate, a commonly used medication used to treat symptoms of endometriosis, impact biomarkers of brain health, Investigate how Orlissa, a commonly used medication used to treat symptoms of endometriosis, impact biomarkers of brain health, Investigate how Oriahnn, a commonly used medication used to treat symptoms of endometriosis, impact biomarkers of brain health
- Volunteers
- 45 people
- Sponsor
- Colorado State University
Dysmenorrhea Primary
The Effect of OMM in the Treatment of Primary Dysmenorrhea Symptoms
Primary dysmenorrhea or simply painful menstruation is a disorder that 45-90% of women experience to varying degrees. The most prominent symptom of dysmenorrhea is crampy suprapubic pain occurring prior to menstruation, closely…
- Trial name
- NCT05208476
- Testing
- Osteopathic manipulative medicine
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Primary Dysmenorrhea
Virtual Reality-Based Relaxation and Exergaming vs. Traditional Relaxation for Primer Dysmenorrhea
The goal of this clinical trial is to investigate the acute effects of virtual reality-based relaxation (immersive VR relaxation) and exergaming (non-immersive VR) compared to traditional Jacobson's relaxation on symptoms of…
- Trial name
- NCT06728306
- Testing
- Immersive Virtual Reality-Based Relaxation, Non-immersive VR-Based Exergaming, Jacobson's Relaxation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Trakya University
Intrauterine Device Expulsion, Adenomyosis, Endometriosis
Clinical Observation of Hysteroscopy-Assisted Placement of Handmade Frameless GyneFix-LNG-IUS (Retrospective Cohort)
This is a retrospective self-controlled observational study. We evaluated the safety and efficacy of a handmade frameless levonorgestrel-releasing intrauterine system (GyneFix-LNG-IUS) in patients at high risk of IUD expulsion.
- Conditions
- Intrauterine Device Expulsion, Adenomyosis, Endometriosis, Menorrhagia, Dysmenorrhea, Abnormal Uterine Bleeding
- Trial name
- Gyne-LNG-IUS (NCT07518693)
- Testing
- Handmade Frameless GyneFix-LNG-IUS
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Yu Wang
Primary Dysmenorrhea, Chronic Pelvic Pain
Evaluation of the Analgesic Effect of Intramyometrial Botulinum Toxin Injection Via Hysteroscopy in Pelvic Pain Suggestive of Dysmenorrhea
The objective of the study is to evaluate the global impression of improvement at 3 months following intramyometrial botulinum toxin injections via hysteroscopy in women with severe primary dysmenorrhea who have failed first-line…
- Trial name
- HYSTEROXINE (NCT06995287)
- Testing
- Xeomin
- Where
- 8 sites in France
- Volunteers
- 222 people
- Sponsor
- Nantes University Hospital
Dysmenorrhea Primary, Obesity and Overweight
Bioptron Light Therapy for Dysmenorrhea in Obese Adolesences: RCT
Dysmenorrhea is the most common health problem in women in the reproductive age(Bakhsh et al., 2022). The primary dysmenorrhea starts shortly after the menarche the pain lasting 1 to 3 days that start just before or at the onset…
- Trial name
- NCT06992349
- Testing
- bioptron light therapy
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Alaa Noureldeen Kora
Endometriosis
A Study to Evaluate the Safety and Effectiveness of Three Asoprisnil Doses in the Treatment of Women With Endometriosis
The objective of this study is to determine the safety and effectiveness of three doses of asoprisnil, compared to placebo, in the treatment of women with endometriosis.
- Trial name
- NCT00160446
- Testing
- Asoprisnil
- Volunteers
- 130 people
- Sponsor
- Abbott
Moderate to Severe Primary Dysmenorrhea
Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in Women With Primary Dysmenorrhea (With Optional Extension) (MK-8342B-059)
The purpose of this study is to assess the etonogestrel (ENG) + 17β-estradiol (E2) vaginal ring's efficacy compared to a placebo vaginal ring in the treatment of dysmenorrhea at Treatment Cycle 2.
- Trial name
- NCT02668783
- Testing
- Etonogestrel (ENG) 125 μg + 17β-estradiol (E2) 300 μg vaginal ring, Ibuprofen
- Volunteers
- 25 people
- Sponsor
- Organon and Co
Endometriosis
Study to Evaluate the Long-Term Safety and Efficacy of Elagolix in Adults With Moderate to Severe Endometriosis-Associated Pain
A randomized study evaluating the continued safety and efficacy of elagolix in the management of moderate to severe endometriosis-associated pain in pre-menopausal women.
- Trial name
- NCT01760954
- Testing
- Elagolix
- Volunteers
- 506 people
- Sponsor
- AbbVie
Dysmenorrhea
Research and Development of WPAPS Based on the Modern Technology of Traditional Chinese Medicine
The goal of this double-blind randomized controlled trial is to determine the efficacy of Warm Palace Analgesic Point Sticker in relieving dysmenorrhea compared to placebo sticker.
- Trial name
- NCT05815654
- Testing
- Warm Palace Analgesic Point Sticker
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Hong Kong Baptist University
Dysmenorrhea, Low Back Pain
Core Stability vs. Traditional Physical Therapy: A Comparative Study on Alleviating Low Back Pain in Dysmenorrhea
Dysmenorrhea is a menstrual disorder defined by the presence of painful cramps of uterine origin that occur during menstruation.
- Trial name
- NCT06807229
- Testing
- Transcutaneous electrical nerve stimulation, stretching exercises
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Delta University for Science and Technology
Menstrual Cycle, Menstrual Distress (Dysmenorrhea)
Menstrual Cycle Symptoms and Female Health
The complexity inherent to the hormonal fluctuations associated with the female menstrual cycle (MC) has contributed, from a methodological perspective in research, to the neglect of women's physiological characteristics and to…
- Conditions
- Menstrual Cycle, Menstrual Distress (Dysmenorrhea), Premenstrual Syndrome, Abnormal Uterine Bleeding (AUB)
- Trial name
- CICLOS (NCT07699224)
- Testing
- Prevalence
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Universidad Rey Juan Carlos
Migraine Disorders
Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as TREXIMA, for Menstrual Migraine in Women With Dysmenorrhea
This study was designed to determine efficacy of TREXIMA compared to placebo for the treatment of a menstrual migraine.
- Trial name
- NCT00329459
- Testing
- sumatriptan succinate/naproxen sodium
- Where
- 34 sites in United States
- Volunteers
- 320 people
- Sponsor
- GlaxoSmithKline
Pain, Postoperative, Neural Therapy of Huneke
Evaluation of the Neural Therapy Effect on Long Term Postoperative Discomforts in Patients Who Undergo Bilateral Tubal Ligation
The aim of this study was to explore the effect of neural therapy on postoperative pain and discomfort such as abdominal swelling; and gynecologic symptoms such as dysmenorrhea, dyspareunia, amount of menstrual bleeding and…
- Conditions
- Pain, Postoperative, Neural Therapy of Huneke, Dysmenorrhea, Dyspareunia
- Trial name
- NCT03761862
- Testing
- Neural Therapy
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Dysmenorrhea
The Effect of vırtual realıty on paın and Sleep qualıty ın Women
The aim of this study is to determine whether a video viewed through virtual reality goggles accompanied by music has an effect on pain and sleep quality in women with dysmenorrhea.
- Trial name
- NCT07633990
- Testing
- experiment, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Hasan Kalyoncu University