Clinical trials: Menstrual Cycle Disorder
Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease
NAFLD in Adolescents and Young Adults With PCOS
This project focuses on an at-risk adolescent and young adult population who may gain long-term health benefits from detection of risk factors at a young age.
- Conditions
- Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome
- Trial name
- NCT02506946
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hypothalamic Amenorrhea, Functional
Health and Lifestyle Support for Functional Hypothalamic Amenorrhea
The goal of this clinical trial is to learn whether a 10-week psychoeducational health and lifestyle intervention can help women with Functional Hypothalamic Amenorrhea (FHA) restore their endocrine balance and menstrual cycles.
- Trial name
- HEAL-FHA (NCT07386223)
- Testing
- Psychoeducaction or treatment as usual, Treatment as usual (TAU)
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Karolinska Institutet
Uterine Adenomyosis, Recurrent Implantation Failure
Aromatase Plus GnRH Analogue Versus GnRH Analog Alone in Adenomyosis
With this study the investigators want to test which is the best medical treatment for symptomatic adenomyosis affecting women undergoing IVF and with previous implantation failure, between Aromatase inhibitor plus GnRH analog…
- Conditions
- Uterine Adenomyosis, Recurrent Implantation Failure, Menstrual Pain
- Trial name
- NCT03421639
- Testing
- GnRH analog (11.25mg Leuprolide acetate), Aromatase inhibitor and GnRH analog, Aromatase and GnRH analog (11.25mg Leuprolide acetate)
- Where
- 3 sites in Albania, Bulgaria and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Menstrual Cycle-Associated Gingivitis
The Effect of Menstrual Cycle On IL-6, TNF-α And Periodontal Status
Aim: Women's menstrual cycle is controlled by the secretion of sex hormones. Sex steroid hormones are thought to be affect to periodontal tissues, wound healing, periodontal disease progression and bone turn over.
- Trial name
- NCT03281109
- Testing
- diagnosis
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Yuzuncu Yil University
Von Willebrand Disease, Congenital Coagulation Factors Deficiency
Evaluation of Menses in Congenital Bleeding Disorders
Menorrhagia is the term used to define excessive menstrual blood losses, as often based on a subjective judgment of women. Many arbitrary values, expressed in milliliters of blood, have been proposed to define this symptom: 60 on…
- Conditions
- Von Willebrand Disease, Congenital Coagulation Factors Deficiency, Haemophilia Carriers
- Trial name
- MEVA-3 (NCT01261936)
- Where
- 3 sites in Italy
- Volunteers
- 30 people
- Sponsor
- University of L'Aquila
Premenstrual Syndrome, PMS
Dutasteride to Treat Women With Menstrually Related Mood Disorders
This study will explore the effects of dutasteride on mood and the stress response across the menstrual cycle. Dutasteride blocks production of neurosteroids-hormones that help regulate the stress response systems.
- Conditions
- Premenstrual Syndrome, PMS, Healthy, Depression
- Trial name
- NCT00082043
- Testing
- Dutasteride
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institute of Mental Health (NIMH)
Root Canal Treatment
Post-Endodontic Pain According to Menstrual Cycle Phases
This study aimed to evaluate whether the phase of the menstrual cycle affects pain after root canal treatment. A total of 99 patients (72 females and 27 males) who needed root canal treatment in lower molar teeth were included.
- Trial name
- PEP-MC (NCT07291518)
- Testing
- root canal treathment
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Ahter Sanal Cikman
Menstrual Pain, Dysmenorrhea
Yoga and Aerobic Exercise Training in Primary Dysmenorrhea
The aim of this study is to compare the effects of aerobic exercise and yoga exercises on menstrual pain parameters (pain severity and duration, analgesic usage), uterine artery blood flow, menstrual stress level, physical…
- Trial name
- NCT05623085
- Testing
- Aerobic exercise, Yoga exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Amenorrhea, Bone Loss
Bone Mass Accrual in Adolescent Athletes
The adolescent and young adult years are a critical window in time for bone mineral accrual. More than 90% of peak bone mass is achieved by 18 years, and data indicate that insults sustained during adolescence and young adulthood…
- Trial name
- 838 (NCT00827151)
- Testing
- Estrogen
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Dysmenorrhoea
Treatment of Dysmenorrhoea With the OVA TENS Apparatus
Dysmenorrhoea (menstrual pain) is a common complaint among women, leading to use of analgesics, reduced quality of life, and interference with daily activities such as going to work or school.
- Trial name
- NCT00225836
- Testing
- OVA (TENS apparatus)
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hospital of Vestfold
Uterine Fibroids (UF)
A Study to Evaluate Changes in Hair in Adult Participants Taking Oral Oriahnn Capsules With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF)
Uterine Fibroids (UF) are benign smooth muscle neoplasms of the uterus that affect women of reproductive age. UFs are one of the leading causes of hospitalizations for gynecological disorders and often lead to hysterectomy.
- Trial name
- Pink Orchid (NCT06058728)
- Where
- United States
- Sponsor
- AbbVie
Premenstrual Syndrome, Quality of Life
The Effect of Laughter Yoga and Premenstrual Symptoms
Premenstrual Syndrome (PMS) describes somatic, cognitive, emotional, and behavioral symptoms that occur in women during the luteal phase of the menstrual cycle and resolve with the onset of menstruation.
- Trial name
- NCT07074314
- Testing
- Laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Menstrual Irregularity
Sonographic Evaluation Of Uterine Fibroids At Different Locations In Patient With Irregular Menstrul Cycle
Uterine fibroids are a major cause of illness in women of a reproductive age. There are many factors involved in the growth and reduction of these common tumors.
- Trial name
- NCT06768879
- Testing
- Ultrasound
- Where
- Pakistan
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Superior University
Fibroid Uterus, Leiomyoma
Safety of Treatment of Uterine Fibroids With Asoprisnil
The objective of this study is to determine the long-term safety of asoprisnil in women with symptomatic uterine fibroids who completed the 6 month Study C02-037.
- Conditions
- Fibroid Uterus, Leiomyoma, Menorrhagia, Metrorrhagia
- Trial name
- NCT00156208
- Testing
- Asoprisnil
- Volunteers
- 166 people
- Sponsor
- Abbott
Uterine Leiomyoma, Uterine Fibroids
Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
The objectives of this randomized withdrawal study are to evaluate the long-term efficacy and safety of the combination of relugolix, estradiol (E2) and norethindrone acetate (NETA), once daily, for up to 104 weeks in patients…
- Trial name
- NCT03751124
- Testing
- Relugolix, Estradiol/norethindrone acetate
- Where
- 104 sites in United States, Brazil and 6 more
- Volunteers
- 229 people
- Sponsor
- Myovant Sciences GmbH
Uterine Fibroids, Leiomyoma
Hysteroscopic Cryomyolysis for the Treatment of Submucosal Leiomyomata
The purpose of the current study is to evaluate the technical success, safety and procedure feasibility of hysteroscopic cryoablation treatment of symptomatic uterine fibroids in women who do not desire further pregnancies using…
- Conditions
- Uterine Fibroids, Leiomyoma, Menorrhagia
- Trial name
- NCT00731341
- Testing
- Cryoablation for the treatment of uterine fibroids
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- Boston Scientific Corporation
Abnormal Uterine Bleeding, Dysmenorrhea
Failed Endometrial Ablation Treatment With Implantable Progesterone (FEAT) Study
The objective of this study is to assess the efficacy of an implantable etonogestrel device in reducing hysterectomy rate in patients with a failed endometrial ablation.
- Trial name
- FEATS (NCT05227456)
- Testing
- Etonogestrel 68mg implant
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Dysmenorrhea, Heavy Menstrual Bleeding
Menstrual Complaints in Adolescents and Adults
The aim of this study is to investigate the prevalence of menstrual complaints and their impact on daily life activities (school/work absence, absence from social activities, sports) in adults and adolescents.
- Conditions
- Dysmenorrhea, Heavy Menstrual Bleeding, Daily Activities, Menstrual Cramps
- Trial name
- MEK app (NCT06921629)
- Testing
- Menstruatie Educatie Kalender (Menstrution Education Calendar) application (MEK-app), Questionnaires
- Where
- Netherlands
- Volunteers
- 2,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Morbid Obesity, Endometrial Pathology
Study of Menstrual Irregularities and Endometrial Pathology in Women Undergoing Bariatric Surgery
Objectives: Given the profound impact of obesity on the genesis of endometrial cancer, this study proposes to prospectively evaluate the baseline prevalence of menstrual irregularities and endometrial pathology in morbidly obese…
- Conditions
- Morbid Obesity, Endometrial Pathology, Menstrual Irregularities
- Trial name
- NCT01473186
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Primary Dysmenorrhea, Dysmenorrhea
Spinal Manipulation For Menstrual Symptoms and Sleep in Individuals With Primary Dysmenorrhea
The goal of this observational study is to evaluate if spinal manipulation (SM) combined with connective tissue massage (CTM) improves pain, menstrual symptoms, depression levels, and sleep quality in women with primary…
- Trial name
- NCT06673537
- Testing
- Connective Tissue Massage (CTM), Spinal Manipulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa