Clinical trials: Menstrual Epilepsy
Catamenial Epilepsy
Fycompa in Catamenial Epilepsy
The purpose of the proposed investigation is to carry out a pilot study of add-on perampanel (Fycompa) in women with perimenstural (C1) catamenial epilepsy.
- Trial name
- NCT05201703
- Testing
- Fycompa, Fycompa with a boost
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Florida
Epilepsy
Role of Hormones in Susceptibility to Seizures in Women With Epilepsy
This study will measure and compare hormone levels in women with catamenial epilepsy (epilepsy in which seizures are more frequent during menstrual periods), women with seizures not related to their menstrual cycle, and normal…
- Trial name
- NCT00044252
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Epilepsy, Drug Resistant Epilepsy
Ketonemia Through Menstrual Cycle
Ketogenic dietary therapies (KDTs) are well-established, safe, non-pharmacologic treatments used for children and adults with drug-resistant epilepsy and other neurological disorders.
- Conditions
- Epilepsy, Drug Resistant Epilepsy, GLUT1DS1, Ketogenic Dieting
- Trial name
- KETOMENS (NCT05234411)
- Testing
- Evaluation of ketogenic diet impact on ketonemia
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Pavia
Partial Epilepsy, Catamenial Epilepsy
A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures
The study will evaluate the effectiveness and safety of an investigational drug-ganaxolone - on partial seizure frequency in adults with epilepsy taking a maximum of 3 antiepileptic medications (AEDs).
- Trial name
- NCT00465517
- Testing
- Ganaxolone
- Where
- 27 sites in United States
- Volunteers
- 147 people
- Sponsor
- Marinus Pharmaceuticals
Epilepsy
Study of Phenobarbital Inhibition of Catamenial Epilepsy
The purpose of this study is to test the effectiveness of low-dose Phenobarbital on the treatment of catamenial epilepsy. We propose that since the catamenial seizures are associated with the reduction in levels of GABA-enhancing…
- Trial name
- NCT00530413
- Testing
- Phenobarbital
- Where
- United States
- Sponsor
- University of Toledo Health Science Campus
Transformed Migraine, Chronic Daily Headache
Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines
This study will compare a local anesthetic technique that has been used to treat subjects suffering from transformed migraines (chronic migraines) versus medical management with traditional antidepressant Amitriptyline / Elavil.
- Trial name
- NCT02090998
- Testing
- SPG Block with 5% Lidocaine gel, Amitriptyline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rutgers, The State University of New Jersey
Epilepsy
Study on Safety and Efficacy of Levetiracetam in the Adjunctive Treatment of Female Subjects With C1 Catamenial Epilepsy
The relationship between hormone cycling/fluctuations and the occurrence of seizures in women has received considerable discussion in the medical literature.
- Trial name
- NCT00630630
- Testing
- Levetiracetam
- Volunteers
- 3 people
- Sponsor
- UCB Pharma
Epilepsies, Partial
Open-label Extension to Protocol 1042-0600
To allow open-label extension to patients who have completed Protocol 1042-0600.
- Trial name
- NCT00512317
- Testing
- ganaxolone
- Where
- 25 sites in United States
- Volunteers
- 123 people
- Sponsor
- Marinus Pharmaceuticals
Epilepsy Menstrual
Interest of a Specific Care Pathway for the Management of Catamenial Epilepsy
This is a study of patients with catamenial epilepsy. Catamenial epilepsies are defined as epileptic seizures during the menstrual cycle. Today, there are no recommendations and no care pathway for these patients.
- Trial name
- EPICAT (NCT05898152)
- Testing
- Data collection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Epilepsy
Women With Epilepsy: Pregnancy Outcomes and Deliveries
This is a three-center prospective case-control study to examine the patterns of fertility among women with epilepsy (WWE) compared to an age-matched group of women without epilepsy (WWoE).
- Trial name
- WEPOD (NCT01259310)
- Where
- 3 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Epilepsy, Seizure
Medium Chain Triglycerides as an Adjunct to the Modified Atkins Diet for Women With Catamenial Epilepsy
The modified Atkins diet (MAD) has been shown to be effective in treating intractable epilepsy. Approximately 55% of the patients started on the diet are women of childbearing age and women with epilepsy often have a pattern of…
- Conditions
- Epilepsy, Seizure, Catamenial Epilepsy, Medically Resistant Epilepsy
- Trial name
- NCT02426047
- Testing
- betaquik®
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Johns Hopkins University
Epilepsy
A Study to Look at Antiepileptic Drug Levels While on Lamictal or Depakote With or Without an Oral Contraceptive
Some antiseizure medication levels are affected by hormones. This study is being done to determine if blood levels of lamotrigine or valproate are affected by the hormones in the birth control pill or the menstrual cycle itself.
- Trial name
- NCT00296413
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Beth Israel Deaconess Medical Center
Epilepsy
Catamenial Epilepsy Treatment
Epilepsy is a disorder in the brain. The brain is full of "nerve" cells. Nerve cells have normal electrical activity to control the many functions of the body.
- Trial name
- NCT01299870
- Testing
- Keishibukuryogan
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Timothy Welty, PharmD
Catamenial Epilepsy
Verapamil and Catamenial Epilepsy
One in 3 epilepsy patients have refractory seizures. This drug resistance is likely related to the over expression of multidrug resistance proteins (MDR).
- Trial name
- NCT00559169
- Testing
- verapamil hyrochloride
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto