Clinical trials: Menstrual Pain
Menstrual Cramps, Women's Health
A Study to Assess the Effect of My Happy Flo on Alleviating Period Symptoms and Heavy Flows.
This clinical study aims to evaluate the effectiveness of My Happy Flo, a dietary supplement, in alleviating period symptoms and heavy menstrual flows.
- Conditions
- Menstrual Cramps, Women's Health, Fatigue
- Trial name
- NCT06522672
- Testing
- My Happy Flo
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- My Happy Flo
Uterine Fibroids, Endometriosis
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
The purpose of this clinical trial to characterize changes in bone mineral density during continuous treatment with relugolix combination tablet for up to 48 months (4 years) and 1 year of post-treatment follow-up in…
- Trial name
- NCT05862272
- Testing
- Relugolix Combination Tablet
- Where
- 120 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
Primary Dysmenorrhea
Efficacy of Vitex Agnus-castus BNO 1095 (20 mg) in Women With Primary Dysmenorrhea
In this Phase III study, the herbal product Vitex agnus-castus BNO 1095 20 mg will be tested. The sponsor would like to find out if treatment with Vitex agnus-castus BNO 1095 20 mg may improve the cramping pain before or during…
- Trial name
- NCT06211049
- Testing
- Vitex agnus-castus BNO 1095 (20 mg)
- Where
- 34 sites in Austria, Czechia and 4 more
- Volunteers
- 335 people
- Sponsor
- Bionorica SE
Dysmenorrhea
Survey on Menstrual Symptoms, Health Related Quality of Life and Work Productivity in Patients Suffering From Pain During Menstruation (Dysmenorrhea) in Japan
In this study researcher want to gain more information on the treatment effect of Low-dose Estrogen Progestin (a hormone treatment) on the health related quality of life and work productivity in patients suffering from menstrual…
- Trial name
- NCT04607382
- Testing
- LEP, NSAIDs and/or Chinese medicine (CM)
- Where
- Japan
- Volunteers
- 397 people
- Sponsor
- Bayer
Endometriosis
A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Women With Endometriosis.
The objective of this study is to determine the safety and efficacy of 3 asoprisnil doses (0.5 mg, 1.5 mg, and 5.0 mg) for 12 weeks in women with endometriosis.
- Trial name
- NCT00160433
- Testing
- Asoprisnil
- Volunteers
- 131 people
- Sponsor
- Abbott
Endometriosis
A Long-Term Study to Evaluate the Safety of Asoprisnil in the Treatment of Women With Endometriosis From Study M01-398
The objective of this study is to determine the long-term safety of asoprisnil 5 mg for 12 months in women with endometriosis from study M01-398.
- Trial name
- NCT00160420
- Testing
- Asoprisnil
- Volunteers
- 73 people
- Sponsor
- Abbott
Endometriosis
A Phase 2 Trial to Investigate Efficacy and Safety of Vipoglanstat in Women With Endometriosis
The main objective of the trial is to evaluate the efficacy of vipoglanstat on endometriosis-related non-menstrual pelvic pain (NMPP).
- Trial name
- NOVA (NCT07260669)
- Testing
- Vipoglanstat
- Where
- 44 sites in Bulgaria, Czechia and 5 more
- Volunteers
- 213 people
- Sponsor
- Gesynta Pharma AB
Dysmenorrhea, Dyspareunia
Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Women
The purpose of the study is to evaluate the efficacy and safety of two doses of ERB-041 (75 mg and 150 mg) relative to placebo on the relief of endometriosis-related symptoms (dysmenorrhea, pelvic pain, and deep dyspareunia) in…
- Conditions
- Dysmenorrhea, Dyspareunia, Endometriosis, Pelvic Pain
- Trial name
- NCT00318500
- Testing
- ERB-041
- Where
- 70 sites in United States, Australia and 5 more
- Volunteers
- 150 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Endometriosis
A Study to Evaluate Safety and Efficacy of Elagolix in Participants With Endometriosis With Associated Moderate to Severe Pain
This is a Phase 3, dose-escalation study designed to evaluate the safety and efficacy of both elagolix alone and elagolix plus estradiol/norethindrone acetate (E2/NETA) over 24 months in the management of endometriosis with…
- Trial name
- NCT03343067
- Testing
- elagolix, estradiol/norethindrone acetate (E2/NETA)
- Where
- 37 sites in United States
- Volunteers
- 11 people
- Sponsor
- AbbVie
Premenstrual Syndrome, Premenstrual Dysphoric Disorder
CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life
This study evaluates the feasibility and efficacy of the Samphire Guided Care (SGC) program a 12-week structured digital health program combining clinician-led onboarding, at-home neuromodulation using the Lutea tDCS device…
- Conditions
- Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Dysmenorrhea, Endometriosis
- Trial name
- CREST (NCT07679074)
- Testing
- Lutea Transcranial Direct Current Stimulation (tDCS) Device, Samphire Guided Care Program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samphire Group, Inc.
Dysmenorrhea
The Impact of Oral Probiotics on Improving the Quality of Life in Patients With Dysmenorrhea.
Menstrual pain is mainly divided into primary dysmenorrhea and secondary dysmenorrhea, the former is caused by menstrual uterine muscle movement; the latter is caused by certain diseases, such as Endometriosis, Uterine fibroids…
- Trial name
- NCT07530081
- Testing
- High dose Probiotic, Low dose probiotic
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Glac Biotech Co., Ltd
Painful Menstruation
The Effect of a Ginger Formula on Menstrual Health vs a Placebo
This study will test whether a standardized ginger extract improves menstrual pain and related symptoms compared with placebo in women with painful periods.
- Trial name
- GinFlow (NCT07894406)
- Testing
- Ginger formula
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Primary Dysmenorrhea
Efficacy and Safety of DEH113 in the Treatment of Menstrual Cramp Pain in Primary Dysmenorrhea: a Pilot Study
This study aims to evaluate the preliminary efficacy and safety of DEH113 in the Treatment of Menstrual Cramps Pain Associated with Primary Dysmenorrhea.
- Trial name
- NCT06555549
- Testing
- DEH113
- Volunteers
- 60 people
- Sponsor
- EMS
Endometriosis Related Pain
SPIRIT 2: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain
The purpose of this study is to determine the benefit and safety of relugolix 40 milligrams (mg) once daily, co-administered with low-dose estradiol (E2) and norethindrone acetate (NETA) compared with placebo for 24 weeks, on…
- Trial name
- NCT03204331
- Testing
- Relugolix, Estradiol/norethindrone acetate
- Where
- 91 sites in United States, Australia and 9 more
- Volunteers
- 623 people
- Sponsor
- Myovant Sciences GmbH
Endometriosis
SPIRIT EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Endometriosis-Associated Pain
The purpose of this study is to evaluate the long-term efficacy and safety of relugolix 40 milligram (mg) once daily co-administered with low-dose estradiol (E2) and norethindrone acetate (NETA) for up to 104 weeks on…
- Trial name
- NCT03654274
- Testing
- Relugolix, Estradiol/norethindrone acetate
- Where
- 169 sites in United States, Argentina and 18 more
- Volunteers
- 802 people
- Sponsor
- Myovant Sciences GmbH
Womens Health, Menstrual Symptoms
Effera Dose Response: Women's Health
The goal of this clinical trial is to learn if a human equivalent lactoferrin supplement (effera®) can improve menstrual symptoms, mood, and quality of life in healthy women aged 18-40.
- Trial name
- NCT07524270
- Testing
- Effera® (human equivalent lactoferrin)
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Helaina Inc.
Uterine Fibroids, Leiomyoma
An Open-Label Study to Evaluate the Effect of Elix Cycle Balance & Elix Daily Harmony on Fibroid-related Symptoms
This is a 24-week, single-arm, open-label, virtual study evaluating the effects of Elix Cycle Balance and Elix Daily Harmony on uterine fibroid-related symptoms and quality of life in 42 participants.
- Conditions
- Uterine Fibroids, Leiomyoma, Menstrual Pain
- Trial name
- NCT07078682
- Testing
- Elix Daily Harmony
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Zenchi, Inc.
Endometriosis
A Study to Assess the Efficacy and Safety of OBE2109 in Subjects With Endometriosis
The primary objective of this study is to assess the efficacy and safety of a range of oral doses of OBE2109 versus placebo, in reducing endometriosis associated pain.
- Trial name
- EDELWEISS (NCT02778399)
- Testing
- OBE2109
- Where
- 86 sites in United States, Poland and 2 more
- Volunteers
- 328 people
- Sponsor
- ObsEva SA
Premenstrual Syndrome, Mastodynia
Efficacy and Safety of 20 mg (2 Tablets of 10mg)VAC BNO 1095 FCT on Cyclic Mastodynia and PMS
The purpose of this study is to proof the efficacy and safety of 20 mg (2 tablets of 10 mg) VAC BNO 1095 film-coated tablets in patients suffering from cyclic mastodynia and PMS (pre menstrual syndrome).
- Trial name
- NCT01870687
- Testing
- 20mg VAC BNO 1095 FCT
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Bionorica SE
Primary Dysmenorrhea
Efficacy and Safety of CDE100 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea
The purpose of this study if to evaluate the efficacy and safety of CDE100 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea.
- Trial name
- ASTRAL (NCT05640232)
- Testing
- CDE100 association, Buscopan® Composto association
- Where
- Brazil
- Volunteers
- 238 people
- Sponsor
- EMS