Clinical trials: Menstrual Problem
Primary Dysmenorrhea
Neuromodulatary Efficacy of Transcranial Direct Current Stimulation in Severe Refractory Primary Dysmenorrhea
Primary Dysmenorrhea (PDM), defined as menstrual pain without discernable organic causes, is inexorably common in adolescent women, about 40-90% of women may suffer from it, and 20% of them can be severe in the context of being…
- Trial name
- NCT03608215
- Testing
- Active tDCS
- Where
- Taiwan
- Volunteers
- 31 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Heavy Menstrual Bleeding
Tranexamic Acid in Adolescents With Heavy Menstrual Bleeding
This is a study to learn more about a drug called Tranexamic acid (TA), otherwise known as Lysteda, and whether or not this drug can decrease menstrual blood loss in young women and lead to an increase in the quality of life.
- Trial name
- NCT01846507
- Testing
- Tranexamic Acid
- Where
- 5 sites in United States
- Volunteers
- 32 people
- Sponsor
- Nationwide Children's Hospital
Heavy Menstrual Bleeding, Uterine Fibroid
LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
The purpose of this study is to determine the benefit of relugolix 40 milligrams (mg) once a day co-administered with estradiol (E2) 1 mg and norethindrone acetate (NETA) 0.5 mg compared with placebo for 24 weeks on heavy…
- Trial name
- NCT03103087
- Testing
- Relugolix, Estradiol/norethindrone acetate
- Where
- 127 sites in United States, Belgium and 6 more
- Volunteers
- 382 people
- Sponsor
- Myovant Sciences GmbH
Primary Dysmenorrhea
Effect of Hegu Point Ice Massage and Music in Dysmenorrhea
Dysmenorrhea, a gynecological health problem that is frequently observed in adolescents and young adult women and often cannot be diagnosed is defined as pelvic pain associated with menstruation.
- Trial name
- NCT05686460
- Testing
- ice massage, music medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Premenstrual Dysphoric Disorder
Deep Transcranial Magnetic Stimulation (dTMS) for the Treatment of Premenstrual Dysphoric Disorder (PMDD)
Premenstrual dysphoric disorder (PMDD) is a hormone-dependent mental condition that causes significant suffering in 5% of women of reproductive age worldwide.
- Trial name
- NCT02448836
- Testing
- dTMS H-coil system:magstim stimulator rapid2,BrainswayH1coil
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Premenstrual Syndrome
Effects of Mandala Coloring on Premenstrual Syndrome
This research was planned as a randomized controlled experimental study in order to reduce premenstrual syndrome symptoms of women with premenstrual syndrome.
- Trial name
- NCT05665972
- Testing
- Mandala coloring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Dysmenorrhoea, Pelvic Pain
The Progression From Dysmenorrhoea to Chronic Pelvic Pain
This is a cross-sectional observational study. For participants resident in Adelaide, South Australia. The study consists of 3 visits to the Pain and Anaesthesia Research Clinic (PARC), within the Royal Adelaide Hospital (RAH).
- Conditions
- Dysmenorrhoea, Pelvic Pain, Chronic Pain
- Trial name
- NCT02636972
- Testing
- OCPs
- Where
- Australia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Endometriosis
Endometriosis Trial: Study of NBI-56418 in Endometriosis
This is a Phase II, multicenter, randomized, double-blind, placebo-controlled, parallel-group study with subjects randomized to one of three treatment groups, placebo, 75 mg and 150 mg in a 1:1:1 ratio.
- Trial name
- NCT00109512
- Testing
- NBI-56418 (GnRH antagonist)
- Where
- 15 sites in United States
- Volunteers
- 76 people
- Sponsor
- Abbott
Menstrual Irregularities
the Effect of Implanon on Menstrual Patterns
This study aims to evaluate whether the timing of postpartum Implanon insertion (immediately postpartum, early postpartum, or late postpartum) affects menstrual patterns
- Trial name
- NCT06936436
- Testing
- Implanon (Etonogestrel)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Premenstrual Dysphoric Disorder
Emotion Regulation-based Internet-delivered Cognitive Behavioural Therapy for Premenstrual Dysphoric Disorder
Premenstrual dysphoric disorder (PMDD) is a debilitating cyclic mental disorder affecting about 2-5% of women of reproductive age.
- Trial name
- Premensis-s (NCT06496139)
- Testing
- Therapist-guided internet-delivered cognitive behavioural therapy
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Uppsala University
Premenstrual Syndrome
Premenstrual Syndrome and Physical Activity Self-Worth
Premenstrual syndrome (PMS) negatively affects the quality of life of millions of women. PMS is a common cyclic disorder characterized by somatic, cognitive, emotional and behavioral symptoms that usually occurs in young and…
- Trial name
- NCT05692479
- Testing
- Premenstrual Syndrome Scale, Women's Physical Activity Self-Worth Inventory, Descriptive data
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Nigde Omer Halisdemir University
Menorrhagia, Dysmenorrhea
Prospective, Non-interventional, Multi-center Safety Study of Mirena for Heavy Menstrual Bleeding and Dysmenorrhea
The primary objective in this study is collecting post-marketing information on the safety. Thus, it includes information under the routine clinical practice on adverse events (AEs) and adverse drug reactions (ADRs) including…
- Trial name
- J-MIRAI (NCT02475356)
- Testing
- Levonorgestrel IUS (Mirena, BAY86-5028)
- Where
- Japan
- Volunteers
- 601 people
- Sponsor
- Bayer
Dysmenorrhea
Study to Assess the Safety and Efficacy of Etoricoxib Versus Ibuprofen in the Treatment of Dysmenorrhea (MK-0663-145 AM1)
This is a study to determine the overall analgesic effect of a single oral dose of etoricoxib compared to ibuprofen in participants with moderate-to-severe primary dysmenorrhea.
- Trial name
- NCT01462370
- Testing
- Etoricoxib, Ibuprofen, Acetaminophen 250 mg, isopropylantipyrine 150 mg and anhydrous caffeine 50 mg
- Volunteers
- 139 people
- Sponsor
- Organon and Co
Primary Dysmenorrhea, Pain
More Than Just p-Values: MCID for the VAS, MSQ and FEMD in Patients With Primary Dysmenorrhea
The aim of this study is to determine the Minimal Clinically Important Difference (MCID) for the Visual Analog Scale (VAS), Menstrual Symptom Questionnaire (MSQ), and Functional and Emotional Measure of Dysmenorrhea (FEMD) in…
- Conditions
- Primary Dysmenorrhea, Pain, Menstrual Discomfort
- Trial name
- NCT06835036
- Testing
- Exercise Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Artvin Coruh University
Menstrual Irregularity
COVID-19 Vaccines and the Menstrual Cycle
The study aimed to explore the effect of different COVID-19 vaccines on menstrual cycle
- Trial name
- NCT05688995
- Testing
- Naser Al-Husban
- Where
- Jordan
- Volunteers
- 617 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Primary Dysmenorrhea
Effects of Functional Exercise Versus High Frequency Transcutaneous Electrical Nerve Stimulation on Primary Dysmenorrhea
The objective of this study is to assess the impacts of utilitarian exercise versus high frequency anscutaneous Electrical Nerve Stimulation on pain and sleep quality in students with primary dysmenorrhea.
- Trial name
- NCT05439096
- Testing
- Functional Exercise, High Frequency Transcutaneous Electrical Nerve Stimulation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Premenstrual Syndrome
Dual-Task Postural Stability in Women With Premstrual Syndrome: A Within-Subject Comparative Study
This within-subject repeated-measures study investigated dual-task postural stability in women with premenstrual syndrome (PMS) by comparing performance during the PMS and non-PMS phases of the menstrual cycle.
- Trial name
- NCT07801651
- Testing
- PMS Group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Deraya University
Menorrhagia
Evaluation of the Endometrial Cavity After Endometrial Ablation
The purpose of this study is to evaluate the shape, size and appearance of the inside of the uterus six months following an endometrial ablation procedure.
- Trial name
- Postablation (NCT02087228)
- Testing
- Genesys HydroTherm Ablator, radiofrequency energy ablation device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Baylor Research Institute
Menorrhagia, Dysfunctional Uterine Bleeding
Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution
Approximately 600,000 women undergo hysterectomy each year in the United States, of which 12% are laparoscopic. The most common indications for hysterectomy are: symptomatic uterine leiomyomas (40.7%), endometriosis (17.7%), and…
- Conditions
- Menorrhagia, Dysfunctional Uterine Bleeding, Leiomyoma, Pelvic Pain
- Trial name
- NCT01581905
- Testing
- Conventional Laparoscopic Hysterectomy (LH), Robot Assisted Hysterectomy
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Premenstrual Syndrome
Comparison of Fluoxetine, Calcium and Placebo for the Treatment of Moderate to Severe Premenstrual Syndrome (PMS)
The purpose of this study is to compare the efficacy of calcium carbonate to fluoxetine in the treatment of moderate to severe PMS. Second, to compare each active agent to a placebo control.
- Trial name
- NCT00965562
- Testing
- Fluoxetine, Calcium
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Donaghue Medical Research Foundation