Clinical trials: Menstrual Problem, open to volunteers
Endometriosis
Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups
The goal of this clinical trial is to learn if a wearable brain stimulation device called NettleEndo can reduce chronic pelvic pain and improve wellbeing in women with endometriosis.
- Trial name
- RELIEF (NCT06974773)
- Testing
- NettleEndo
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Samphire Group, Inc.
PMDD, Premenstrual Dysphoric Disorder (PMDD)
Identification and Validation of Epigenetic Biomarkers of PMDD
This research is being done to examine epigenetic markers and mood changes across the menstrual cycle, particularly in premenstrual dysphoric disorder (PMDD).
- Conditions
- PMDD, Premenstrual Dysphoric Disorder (PMDD), Premenstrual Syndrome-PMS, Premenstrual Syndrome
- Trial name
- BIO (NCT06771583)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Heavy Menstrual Bleeding, Bleeding Disorder
Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study
The goal of this multicenter prospective observational study and registry of U.S. adolescents and young adults with heritable bleeding disorders is to determine the bleeding outcomes, satisfaction, hemostatic parameter changes…
- Conditions
- Heavy Menstrual Bleeding, Bleeding Disorder, Von Willebrand Diseases
- Trial name
- HMB-BD (NCT05916469)
- Testing
- Levonorgestrel Intrauterine System, Norethindrone Acetate
- Where
- 9 sites in United States
- Volunteers
- 300 people
- Sponsor
- Oregon Health and Science University
Menstrual Irregularities
the Effect of Implanon on Menstrual Patterns
This study aims to evaluate whether the timing of postpartum Implanon insertion (immediately postpartum, early postpartum, or late postpartum) affects menstrual patterns
- Trial name
- NCT06936436
- Testing
- Implanon (Etonogestrel)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Premenstrual Dysphoric Disorder
Emotion Regulation-based Internet-delivered Cognitive Behavioural Therapy for Premenstrual Dysphoric Disorder
Premenstrual dysphoric disorder (PMDD) is a debilitating cyclic mental disorder affecting about 2-5% of women of reproductive age.
- Trial name
- Premensis-s (NCT06496139)
- Testing
- Therapist-guided internet-delivered cognitive behavioural therapy
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Uppsala University
Primary Dysmenorrhea
Primary Dysmenorrhea and Comfort Theory
Dysmenorrhea is defined as lower abdominal pain experienced during menstruation. It is divided into two types: primary dysmenorrhea and secondary dysmenorrhea.
- Trial name
- NCT07376759
- Testing
- Comfort Theory-Based Education
- Volunteers
- 80 people
- Sponsor
- Ordu University
Adenomyosis, Adenomyoma of Uterus
Ultrasound-Guided Radiofrequency Ablation for Focal Adenomyosis
This single-center, single-arm, open-label study evaluates the efficacy and safety of ultrasound-guided radiofrequency ablation (RFA) in women with symptomatic focal adenomyosis who wish to preserve the uterus.
- Trial name
- RFA-ADENO-USG (NCT07906535)
- Testing
- Myoblate Radiofrequency Ablation System (Mygen V-1000 generator)
- Where
- Czechia
- Volunteers
- 41 people
- Sponsor
- University Hospital Pilsen
PCOS (Polycystic Ovary Syndrome), Obese Adolescents
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)
This pilot randomized controlled study will plan to enroll 36 adolescent females with Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) to evaluate the effectiveness and feasibility of a tailored…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Obese Adolescents, Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight Adolescents
- Trial name
- Beef+ (NCT07780188)
- Testing
- Beef+
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Texas A&M University
Type 1 Diabetes, Hypoglycemia
Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes
The objectives of this study are to examine how sex hormones (use of hormonal birth control, menstrual cycle phase) impact glycemic control among women with type 1 diabetes (T1D), and to test adjustments to insulin dosing and…
- Conditions
- Type 1 Diabetes, Hypoglycemia, Hyperglycaemia Due to Type 1 Diabetes Mellitus, Menstruation Disturbances
- Trial name
- MERIT (NCT06297980)
- Testing
- Personalized modifications to treatment to address menstrual cycle effects on glycemia
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Amenorrhea
Retrospective Observational Evaluation of the Bone Mineral Density Outcome in Young Women With Amenorrhea
The study aims to evaluate the outcomes of different estrogen therapy regimens in patients with amenorrhea who face prolonged periods of hypoestrogenism.
- Trial name
- NCT07015476
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Primary Dysmenorrhea (PD), Menstrual Pain
Transcutaneous Cervical Vagus Nerve Stimulation for Primary Dysmenorrhea
This randomized, sham-controlled, parallel-group clinical trial will investigate the effects of bilateral transcutaneous cervical vagus nerve stimulation (tcVNS) on menstrual pain and related clinical outcomes in women with…
- Trial name
- tcVNS-PD (NCT07880080)
- Testing
- Transcutaneous Cervical Vagus Nerve Stimulation
- Volunteers
- 70 people
- Sponsor
- Sinop University
Premenstrual Syndrome-PMS
Effects of Yoga on Balance, Cognition, Posture, and Body Awareness in Premenstrual Syndrome (PMS)
Premenstrual syndrome (PMS) is characterized by a combination of cognitive, somatic, behavioral, and emotional disorders that occur during the late luteal phase of the menstrual cycle, resolve rapidly after menstruation, and can…
- Trial name
- NCT06785766
- Testing
- Yoga-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Democracy University
Dysmenorrhea
Adolescent Dysmenorrhoea as a Risk Factor for Chronic Pain: Clinical Cohort Study
This study aims to understand whether changes in a variety of body systems which are seen in adult women with period pain are also seen in adolescents in the first few years of having periods.
- Trial name
- RoADPain (NCT06353789)
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Dysmenorrhea Primary
Taping and PMR Effects in Primary Dysmenorrhea
The study is randomized controlled trial,The study conducted in two groups. Group A has given the kinesiology taping on the lower abdomen and back for 1-3 days with progressive muscle relaxation technique for 10-20 minutes and a…
- Trial name
- NCT06761755
- Testing
- hot pack , K taping , Progressive muscle relaxation
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Premenstrual Syndrome
Aerobic Exercises Versus Sub Occipital Myofascial Release on Memory Function in Females With Premenstrual Syndrome.
This study will be conducted to investigate the effect of aerobic exercises versus sub occipital Myofascial release on memory functions in females with premenstrual syndrome.
- Trial name
- NCT07684495
- Testing
- Aerobic exercise, Sub occipital myofascial release
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Menorrhagia Due to Benign Causes
Reframing Endometrial Physiology by Advanced Integrated Research
Heavy menstrual bleeding (HMB) affects 1 in 3 women and can significantly impact quality of life. Despite its prevalence, there is no accessible and accurate diagnostic test.
- Trial name
- REPAIR (NCT07557992)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Painful Menstruation, Relaxation; Back Ligaments
Impact of Virtual Reality on Painful Menstruation
To investigate the effect of virtual reality on painful menstruation in adolescent female
- Trial name
- VR (NCT06961396)
- Testing
- Relaxation Technique, Pain treatment
- Where
- 2 sites in Egypt, Jordan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- New Ismailia National University
Dysmenorrhea, Menstrual Pain
Vaginal Sildenafil for Primary Dysmenorrhea
This open-label, non-randomized mechanistic study will evaluate whether a single 100 mg vaginal sildenafil citrate suppository reduces uterine hypercontractility during menstruation in adults with moderate-to-severe dysmenorrhea.
- Conditions
- Dysmenorrhea, Menstrual Pain, Endometriosis, Uterine Fibroid
- Trial name
- SILDYS (NCT07508358)
- Testing
- Sildenafil citrate vaginal suppository
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kevin Hellman
Heavy Menstrual Bleeding, Bleeding Disorder
Hormonal Management of Heavy Menstrual Bleeding in Adolescents
The goal of this study is to evaluate whether hormonal medications (such as contraceptive pill, patch, injectable progestins and hormonal intra-uterine device) have similar efficacy at managing heavy menstrual bleeding in…
- Trial name
- JAdoRE (NCT06740929)
- Where
- Switzerland
- Volunteers
- 163 people
- Sponsor
- University Hospital, Geneva
Polycystic Ovarian Syndrome in Adolescent Females, Obesity (Disorder)
Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)
The prevalence of childhood obesity in the United States has more than tripled in the past four decades affecting one in every five adolescent girls and is disproportionally higher among racial and/or ethnic minorities.
- Trial name
- NCT07169136
- Testing
- GLP-1 Receptor Agonists
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic