Clinical trials: Menstruation Disorders
Anorexia Nervosa
Estradiol and Fear Extinction in Anorexia Nervosa (AN)
The purpose of this study is to determine whether estrogen may help reduce fear of high calorie-density foods in weight-restored women with Anorexia Nervosa (AN).
- Trial name
- NCT02792153
- Testing
- Estradiol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Heavy Uterine Bleeding, Uterine Fibroids
Safety and Efficacy in Premenopausal Women With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF)
This is a Phase 2b randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of elagolix alone and in combination with add-back therapy versus placebo on heavy menstrual bleeding in premenopausal women…
- Trial name
- NCT01817530
- Testing
- Elagolix, 0.5 mg estradiol / 0.1 mg norethindrone acetate, 1 mg estradiol / 0.5 mg norethindrone acetate
- Volunteers
- 571 people
- Sponsor
- AbbVie
Premenstrual Syndrome
Premenstrual Syndrome and Interpersonal Counseling
This study aims to test the effectiveness of interpersonal counseling in PMS symptom management in university students experiencing PMS symptoms.
- Trial name
- NCT04838691
- Testing
- interpersonal counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Dysmenorrhea
Effectiveness of the Transcutaneous Electrical Nerve Stimulation in Dysmenorrhea
Hypothesis: What is the best modulation of pulse frequency in transcutaneous electrical nerve stimulation in dysmenorrhea? Purpose: To determine the effect of hypoalgesia frequency modulation pulse by transcutaneous electrical…
- Trial name
- NCT01455285
- Testing
- transcutaneous electrical nerve stimulation
- Where
- Brazil
- Sponsor
- Universidade Federal do Piauí
Primary Dysmenorrhea, Menstrual Pain
Effect of Virtual Reality on Pain and Anxiety in Women With Dysmenorrhea
Dysmenorrhea, or painful menstrual periods, is a common condition that can affect daily activities and quality of life. This study aims to evaluate whether using virtual reality (VR) can reduce pain and anxiety in women with…
- Conditions
- Primary Dysmenorrhea, Menstrual Pain, Anxiety
- Trial name
- VR (NCT07853508)
- Testing
- Virtual Reality
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Dysmenorrhea
VA111913 TS: First in Human Study
This is a first-in-human study of VA111913 TS, a new chemical entity being developed for the treatment of dysmenorrhea. This study is designed to investigate determine the safety, tolerability and pharmacokinetics of VA111913 TS…
- Trial name
- NCT00769964
- Where
- United Kingdom
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Vantia Ltd
Heavy Menstrual Bleeding
Evaluation of 4th Generation Bipolar Radiofrequency Endometrial Ablation Device
All women presenting to the gynaecology outpatient clinic with heavy menstrual bleeding (HMB) in the absence of recognizable pelvic pathology, as determined by one or all of a normal pelvic ultrasound, hysteroscopy and / or…
- Trial name
- NCT02449304
- Testing
- Endometrial ablation (4th gen)
- Volunteers
- 50 people
- Sponsor
- Birmingham Women's NHS Foundation Trust
PMS, Menstrual Cramp
A Randomized Placebo-Controlled Study to Evaluate the Effects of a Gummy and Capsule Supplement on Symptoms of Premenstrual Syndrome
This virtual, randomized, placebo-controlled clinical trial evaluates the effectiveness of a PMS capsule and PMS gummy in alleviating premenstrual syndrome symptoms over 12 weeks.
- Conditions
- PMS, Menstrual Cramp, Mood Change
- Trial name
- NCT06763809
- Testing
- PMS Capsule, PMS Gummy
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Semaine Health
Dysmenorrhea
Adolescent Dysmenorrhoea as a Risk Factor for Chronic Pain: Clinical Cohort Study
This study aims to understand whether changes in a variety of body systems which are seen in adult women with period pain are also seen in adolescents in the first few years of having periods.
- Trial name
- RoADPain (NCT06353789)
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Menstrual Irregularity
Timing of Energy Availability on Menstrual Cycle Function
The primary aim of this clinical trial is to evaluate how fasted prolonged exercise may influence circulating reproductive hormones (i.e., estradiol, progesterone, luteinizing hormone) and menstrual cycle length when energy…
- Trial name
- FAST (NCT06471582)
- Testing
- Artificially Sweetened Carbohydrate Beverage, Artificially Sweetened Beverage
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Primary Dysmenorrhea
Effect of Hegu Point Ice Massage and Music in Dysmenorrhea
Dysmenorrhea, a gynecological health problem that is frequently observed in adolescents and young adult women and often cannot be diagnosed is defined as pelvic pain associated with menstruation.
- Trial name
- NCT05686460
- Testing
- ice massage, music medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Premenstrual Syndrome
Effects of a Female Hormone Balance Supplement on Premenstrual Syndrome Symptoms
This virtual single-group study evaluates the effects of the FemmeBalance supplement on symptoms of premenstrual syndrome (PMS) over four menstrual cycles.
- Trial name
- NCT07018479
- Testing
- FemmeBalance Supplement Group
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- VINABAS FORMULATIONS SL
Menorrhagia, Heavy Menstrual Bleeding
Minitouch Endometrial Ablation System Treatment for Menorrhagia: An Evaluation of Safety & Effectiveness
The EASE Clinical Trial is prospective, multi-center, single-arm (open-label), non-randomized, clinical trial to evaluate the Minitouch Endometrial Ablation System ("Minitouch System") in premenopausal women with menorrhagia.
- Conditions
- Menorrhagia, Heavy Menstrual Bleeding, Heavy Uterine Bleeding
- Trial name
- NCT04267562
- Testing
- Minitouch System
- Where
- 5 sites in United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- MicroCube, LLC
Leiomyoma, Uterine Fibroids
Fibroid Ablation Study - Large Fibroids
The purpose of this study is to establish the effectiveness and confirm the safety of the VizAblate System in the ablation of large (> 5 cm) symptomatic uterine fibroids.
- Conditions
- Leiomyoma, Uterine Fibroids, Menorrhagia
- Trial name
- FAST-L (NCT01539187)
- Testing
- VizAblate System
- Where
- 10 sites in Mexico, Netherlands and 1 more
- Volunteers
- 6 people
- Sponsor
- Gynesonics
Primary Ovarian Insufficiency, Low Ovarian Reserve
Rejuvenation of Premature Ovarian Failure With Stem Cells
The ROSE-1 study is designed to determine the efficacy of bone marrow derived stem cell therapy on ovarian function recovery in subjects with idiopathic and other types of premature or primary ovarian failure (POF or POI) and low…
- Conditions
- Primary Ovarian Insufficiency, Low Ovarian Reserve, Premature Ovarian Failure
- Trial name
- ROSE-1 (NCT02696889)
- Testing
- ROSE-1 Protocol
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Illinois Chicago
Dysmenorrhea
Effects of Interferential Current and Kinesio Taping Added to Pelvic Floor Muscle Exercises in Women With Primary Dysmenorrhea
Primary dysmenorrhea can adversely affect pain, sleep, and health-related quality of life in young women. This study will investigate and compare the effects of interferential current (IFC) and Kinesio taping (KT) added to pelvic…
- Trial name
- NCT07831421
- Testing
- pelvic floor muscle training, Interferential current, Kinesio taping
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Major Depressive Episode
Depressive Symptoms and Subjective Stress in the Course of the Menstrual Cycle - an Ambulatory Assessment Study.
Background: Major changes in female sex hormone concentrations influence the development of depressive symptoms in women. This hypothesis has been thoroughly investigated with regard to the menopause, the postpartal phase and…
- Trial name
- DepCy (NCT04086316)
- Where
- Germany
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
Seed Cycling, Nutrition Habits
The Effect of Seed Cycling-Based Nutritional Intervention on Premenstrual Symptoms
This study aims to investigate the effects of the seed-cycling intervention on premenstrual symptoms and nutritional status. At the beginning of the study, written informed consent will be obtained from all individuals who agree…
- Conditions
- Seed Cycling, Nutrition Habits, Premenstrual Syndrome-PMS
- Trial name
- NCT07575698
- Testing
- Seed consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Primary Dysmenorrhea
Assessment of the Uterus Using Ultrasonographic Elastography in Women with Dysmenorrhea
The aim of this study is to perform sonoelastographic assessment of the uterus in patients diagnosed with primary dysmenorrhea and to compare these measurements with sonoelastographic evaluations of the uteri in asymptomatic…
- Trial name
- NCT06606834
- Testing
- sonoelastography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Diabetes Mellitus, Type 1
Trajectories in Insulin Sensitivity Across MEnstrual cycleS in Women With Type 1 Diabetes
Standardized longitudinal data collection of diabetes management relevant factors in women with T1D (insulin requirements, glucose variability, nutritional information, and menstrual cycle information) to identify categories of…
- Trial name
- TIMES (NCT06282055)
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 350 people
- Sponsor
- DCB Research AG