Clinical trials: Mental
Auditory Perceptual Disorders, Aging Problems
Auditory Temporal Processes in Aging
Older people experience great difficulty understanding speech, especially accented English, and this problem is expected to increase with the influx of immigrants who provide services to the elderly population.
- Trial name
- NCT03468660
- Testing
- Auditory training with feedback, Listening paradigm with no feedback
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Post-traumatic Stress Disorder
Clinician-Assisted Videofeedback Exposure-Approach Therapy (CAVEAT) Trial
The first study proposed is a small (n= 10 to 12 maximum) open feasibility trial of CAVEAT which is a 16-session manualized brief psychotherapy prototcol that is designed to help mothers of infants and young children, whereby the…
- Trial name
- CAVEAT (NCT05927324)
- Testing
- CAVEAT
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Alzheimer Disease
Study of Genetic Alzheimer's Disease Mutation Carriers in Preclinical Stages of the Disease 18F-Florbetaben Positron Emission Tomography Study
The main purpose of the study is to assess safety of a single dose of FBB followed by PET scan in individuals at risk of genetic Alzheimer's disease.
- Trial name
- NCT02362880
- Testing
- Florbetaben
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Judit Pich Martínez
Delirium
Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium
The use of weighted blankets to avert or alleviate Delirium in Adult ICU patients.
- Trial name
- NCT06161480
- Testing
- Weighted Blanket
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Inattention, Cognitive Training
RECOGNeyes Gaze-Control Training
RECOGNeyes is a computer game developed by members of the research team to improve attention in people who find it hard to "keep their eyes on the task".
- Conditions
- Inattention, Cognitive Training, Cognitive Control, Oculomotor Dysfunction
- Trial name
- NCT06691646
- Testing
- Gaze-control training game
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Schizophrenia
Elpipodect (MK-8189) Multiple Dose Study in Healthy Volunteers and Schizophrenia Participants (MK-8189-003)
This 3-part dose titration study will assess elpipodect safety, tolerability, pharmacokinetics (PK), and central nervous system activity.
- Trial name
- NCT02181803
- Testing
- Elpipodect, Base Monotherapy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Alzheimer Disease, Neurodegenerative Diseases
Cognitive Impairment Cohort Study of the Elderly Population in YuGarden
The goal of this prospective observational research with an 8-year follow-up is to study the cognitive changes in the elderly in YuGarden community, Shanghai, China.
- Conditions
- Alzheimer Disease, Neurodegenerative Diseases, Cognitive Impairment, Mild Cognitive Impairment
- Trial name
- NCT06325527
- Where
- China
- Volunteers
- 1,872 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Anxiety, Opioid Use
Effects of Hypnosis Therapy on Outcomes in Total Knee Replacement
The purpose of this study is to collect information to evaluate the role of the psychogenic component of pain induced by anxiety on postoperative outcomes in major orthopaedic surgery and to determine whether hypnosis therapy…
- Trial name
- NCT05818969
- Testing
- Hypnosis Therapy
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Foundation for Orthopaedic Research and Education
Anorexia Nervosa
Dopamine Receptor Contributions to Prediction Error and Reversal Learning in Anorexia Nervosa
Anorexia nervosa (AN) is an eating disorder associated with intense fear of weight gain, food refusal, and severe weight loss. AN has the highest mortality rate among the psychiatric disorders; however, little is known about…
- Trial name
- NCT04128683
- Testing
- amisulpride, bromocriptine
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hypopituitarism, Sleep Wake Disorders
Sleep Disorders in Hypothalamic and Pituitary Damage
Hypothalamus has a key role in multiple vital functions, including regulation of sleep-wake cycles. Oxytocin (OT), a neurohormone synthetized in the hypothalamus, has a wide range of physiological functions, including a putative…
- Conditions
- Hypopituitarism, Sleep Wake Disorders, Hypothalamic Diseases, Oxytocin Deficiency
- Trial name
- SDHPD (NCT07143266)
- Testing
- This is an observational study. No drugs will be administered
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Bipolar Disorder
Sleep Deprivation and Advancement of Sleep Period as Treatment for Bipolar Depression.
The purpose of this study is to determine if sleep deprivation and sleep phase advancement is effective treatment of bipolar patients in a depressive phase.
- Trial name
- NCT00229151
- Testing
- Sleep deprivation and sleep phase advancement, usual treatment
- Where
- Norway
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Work Stress, Sleep Disturbance
The Use of Worktime Planning Tools in the Finnish Public Sector. A Quasi-experimental Study (PLANTOOLS)
This study aims to investigate whether use of interactive worktime planning tools that support work-time control (possibilities to influence individual shift rosters, i.e., participatory rostering) and guide for health-supporting…
- Trial name
- PLANTOOLS (NCT02775331)
- Testing
- Shift planning with self-rostering and shift ergonomics, Shift planning with shift ergonomics
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Finnish Institute of Occupational Health
Anxiety, Parenting
Sowing the Seeds of Confidence: Brief Online Group Parenting Programme for Anxious Parents of 1-3 Year Olds
To pilot a brief group early intervention aimed at reducing or preventing the intergenerational transmission of anxiety, with parents whose child is between 12 and 47 months.
- Trial name
- StS (NCT04556331)
- Testing
- Parenting programme (cognitive behavioural) aimed at reducing generational transmission of anxiety
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- King's College London
ADHD, ADHD - Attention Deficit Disorder With Hyperactivity
Developing Microbiome and Dietary Strategies Based on Chrono-nutrition for Targeting ADHD
Study objectives This project seeks to understand how an intervention based on time-restricted eating (ChronoFeeding or CF) can improve quality of life, behavior, sleep, and gut health in adults with ADHD (Attention Deficit…
- Trial name
- CronoNutriBiom (NCT07821060)
- Testing
- Circadian fasting
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Spanish National Research Council
Global Health of Asylum Seekers in France
Prevalence of Mental Disorder and Somatic Co-morbidities Among Asylum Seekers in Marseille
Introduction : World Health Organization (WHO) considers that the heterogeneity of concepts and definitions of migrants is an obstacle to obtaining evidence to inform public health policies.
- Trial name
- PREMENTADA (NCT05423782)
- Where
- France
- Volunteers
- 419 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
ADHD, Behavioral Disorder
Randomized Controlled Trial of the Myndlift BPT App
We propose addressing these aims by conducting a randomized controlled trial (RCT) that will evaluate the hybrid BPT (Myndlift BPT) compared to a wait-list control group.
- Trial name
- NCT05182424
- Testing
- Myndlift BPT App & As-Needed Therapist Support
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- New York University
Knee Osteoarthritis, Knee Pain Chronic
Gabapentin Regimens and Their Effects on Opioid Consumption
The purpose of this study is to determine the best strategy of administering gabapentin in connection with our current approach to perioperative pain management.
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Opioid Use, Opioid Dependence
- Trial name
- NCT03334903
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Mental Illness
Homelessness Prevention: Psychiatric Care With Representative Payeeship
Money management is a neglected issue in maintaining persons with mental illness in the community. This randomized controlled trial (RCT) assessed whether a community-based representative payee program, i.e., money management of…
- Trial name
- NCT00057161
- Testing
- Coordinated Representative Payeeship with Case Management
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Preschool Age Children, Preschool Education
The Building Resilience Program: Examining Self-Regulation, Behavior, and Resilience in Under-Resourced Preschoolers With ACEs
# Brief Summary The goal of this clinical trial is to learn if a occupational therapy-led trauma-informed care intervention can improve resilience, self-regulation, coping skills, and emotional health in preschoolers ages 2-4…
- Conditions
- Preschool Age Children, Preschool Education, Adverse Childhood Experience, Mental Health
- Trial name
- NCT07170605
- Testing
- Mental health, positive coping strategies promoting self-regulation and adaptive skills, Standard care/School Readiness Condition
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cleveland State University
Stress Disorders, Post-Traumatic
Evaluation of PTSD Family Coach, a Mobile Phone App for Family Members of Individuals With PTSD
The proposed pilot study is designed to test the feasibility, acceptability, and potential effectiveness of a mobile phone application (app) developed by the VA National Center for PTSD (VA NCPTSD) for use by family members of…
- Trial name
- NCT02486705
- Testing
- PTSD Family Coach Full, PTSD Family Coach Basic
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
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