Clinical trials: Mental
Psychiatric Disorders
Influence of Oxytocin on the Startle Reflex and on Its Modulation
Oxytocin (OXT) is currently regarded as a crucial neuropeptide in the mediation of various human social behaviors, e.g. social affiliation, social recognition, and the modulation of anxiety, mood, and aggression.
- Trial name
- NCT01066299
- Testing
- Syntocinon®, inactive nasal spray
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Schizophrenia
The Hi-tACS on Cognitive Function in Patients With Schizophrenia
This study is a double-blind, randomized, controlled intervention study aimed at exploring whether high-frequency transcranial alternating current stimulation (Hi-tACS) can improve cognitive impairment in patients with…
- Trial name
- NCT06470516
- Testing
- high-frequency transcranial alternating current stimulation
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Sir Run Run Shaw Hospital
Fibrinogen Abnormality, Telomere Length, Mean Leukocyte
Pediatric ACEs Screening and Resiliency Study
Stressful and traumatic experiences in childhood (Adverse Childhood Events, or ACEs) have been associated with poor health outcomes that extend into adulthood.
- Conditions
- Fibrinogen Abnormality, Telomere Length, Mean Leukocyte, Atopic, Acute Infection
- Trial name
- PEARLS (NCT04182906)
- Testing
- Care Coordination, Resiliency Clinic, Usual Care
- Where
- United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Schizophrenia, Bipolar Disorder
Indicated Prevention of Psychotic Disorders With Low-dose Lithium
This study investigates the neuroprotective properties of low-dose lithium in young individuals at ultra-high risk of developping a first psychotic episode.
- Conditions
- Schizophrenia, Bipolar Disorder, Psychotic Disorders
- Trial name
- NCT00202306
- Testing
- lithium carbonate
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- Melbourne Health
Eating Disorders, Anorexia Nervosa
A Clinical Trial Into the Efficacy of rTMS Treatment for Treating Anorexia Nervosa and Bulimia Nervosa
This is a pilot study to test the efficacy of repetitive transcranial magnetic stimulation (rTMS) in treating individuals with Anorexia Nervosa and Bulimia Nervosa.
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa
- Trial name
- NCT04061304
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
Post-Traumatic Stress Disorder
Guitars for Vets: Evaluating Psychological Outcome of a Novel Music Therapy
Post traumatic Stress disorder (PTSD) is a common condition for persons who have served in the Armed services during combat or deployment.
- Trial name
- NCT01229904
- Testing
- music therapy with guitar lessons
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- US Department of Veterans Affairs
Consciousness Disorders
Etiologies, Definitive Diagnosis and Patient Outcomes in Altered Level of Consciousness in the Emergency Department
When someone starts acting differently in terms of how alert or awake they are, it can be a tough situation for emergency (ER) department doctors.e exact and definitive etiologies of ALOC that can be intracranial or extracranial.
- Trial name
- NCT06744114
- Testing
- Consciousness in the Emergency Department
- Where
- Pakistan
- Volunteers
- 1 people
- Sponsor
- Superior University
Depression, Anxiety Disorders
School Withdrawal in Adolescents
The aim of the study is to evaluate the impact of the outpatient ambulatory child psychiatric care system on the functioning of anxio-depressive adolescents in school retreat by describing the modalities of individual psychic…
- Conditions
- Depression, Anxiety Disorders, Obsessive-Compulsive Disorder, Behavior Disorders
- Trial name
- DESCOL (NCT03904784)
- Testing
- school withdrawal teenagers
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Restless Legs Syndrome, Pregnant
The Effect of Hot and Cold Water Application on Pregnant Women With Restless Leg Syndrome
This study was planned as a randomized controlled study to determine the effect of hot and cold water application on complaints and sleep quality in pregnant women with restless legs syndrome (RLS).
- Conditions
- Restless Legs Syndrome, Pregnant, Sleep Disorder
- Trial name
- RLS (NCT04786314)
- Testing
- Hot Water Application, Cold Water Application
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Violence, Gender-Based
Evaluation of the WiseGuyz Program for Adolescent Boys
Adolescent dating violence (ADV) is a pressing public health problem in North America, and strategies to prevent perpetration are needed.
- Trial name
- NCT03994016
- Testing
- WiseGuyz
- Where
- Canada
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Mild Cognitive Impairment
A Computer-based Cognitive Stimulation in Mild Cognitive Impairment With White Matter Hyperintensities
This is a non-pharmacological study evaluating the impact of a computerized cognitive stimulation program on verbal learning and on the progression white matter hyperintensities in elderly with mild cognitive impairment.
- Trial name
- NCT03195816
- Testing
- Computerized Cognitive training
- Volunteers
- 90 people
- Sponsor
- Leila DJABELKHIR
Obesity
"Program "Cerdanya on Fitness" to Improve the Lifestyle of People With Obesity in Cerdanya (CF).
To evaluate the effectiveness of an intervention program called "Cerdanya on fitness" based on the prescription of physical activity, healthy nutritional habits and the promotion of positive mental health, adapted to people with…
- Trial name
- CF (NCT05420116)
- Testing
- Cerdanya on Fitness
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Anxiety Disorders
Modulating Escape Using Focused Ultrasound
This is a study to find out if a cutting-edge technology called transcranial focused ultrasound (tFUS) can be used to treat how people with anxiety or related concerns cope with emotional situations.
- Trial name
- NCT06273904
- Testing
- Active transcranial focused ultrasound (tFUS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Clinical High Risk for Psychosis (CHR), Psychotic Disorders
Accelerated Neuromodulation Therapy and Neurocomputational Biomarkers in Individuals at Clinical High Risk for Psychosis
The goal of this study is to learn whether an accelerated form of neuromodulation therapy is safe, feasible, and well tolerated in young people at clinical high risk for psychosis (CHR-P), and whether it is associated with…
- Conditions
- Clinical High Risk for Psychosis (CHR), Psychotic Disorders, Prodromal Symptoms
- Trial name
- TMS-CHR (NCT07786714)
- Testing
- Active Intermittent Theta Burst Stimulation (BEAM-F3 Targeting)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Douglas Mental Health University Institute
Alzheimer's Disease
Safety and Efficacy Study of ABT-089 in Adults With Mild to Moderate Alzheimer's Disease
The purpose of this study is to test if the investigational medication ABT-089 is a safe and effective treatment for Alzheimer's disease.
- Trial name
- NCT00555204
- Testing
- ABT-089
- Where
- 42 sites in United States
- Volunteers
- 337 people
- Sponsor
- Abbott
Cancer, Myocarditis
Randomized Controlled Study Evaluating the Efficacy of Hypnosis in Nuclear Medicine
In Nuclear Medicine, the examinations are long (20-60 minutes) and the patients must remain immobile, sometimes fasting. The anxiety of the latter can lead to poor quality examinations and sometimes, although already injected…
- Conditions
- Cancer, Myocarditis, Alzheimer Disease, Parkinson
- Trial name
- HYDEM (NCT06116084)
- Testing
- Ericksonian Hypnosis, Hypnosis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Mobility, Depressive Symptoms
Effectiveness of AMICOPE Intervention to Maintain Self-Perceived Health and Intrinsic Capacity in Older People
In their day to day, persons do from simple to more or less complicated tasks and activities (ie: stand from a chair, open a door, shopping, read, drive, play chess, remind an appointment...).
- Conditions
- Mobility, Depressive Symptoms, Nutrition, Healthy, Cognitive Decline
- Trial name
- EFICIS (NCT05249504)
- Testing
- VIVIFRAIL, Nutrition, Psychology
- Volunteers
- 212 people
- Sponsor
- Fundacio Salut i Envelliment UAB
Parent Training, Psychoeducation
Development and Effectiveness of a Micro-Psychoeducation Program for Parents of Children With ADHD in Disaster Situations
Abstract Disasters are among the major crisis situations that adversely affect children's psychological well-being, emotional regulation, and adaptation.
- Trial name
- ADHD (NCT07777016)
- Testing
- articipants in the intervention group received the micro-psychoeducation program.
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Schizophrenia
A Placebo-Controlled Study of Physiologic Effects of L-methylfolate in Schizophrenia Patients
This study is a 12-week, double-blind, placebo-controlled trial of L-methylfolate 15 mg/d supplementation in schizophrenia patients with mild or greater negative symptoms.
- Trial name
- NCT01091506
- Testing
- L-methylfolate
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Pamlab, Inc.
Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4, Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4
Study to Evaluate the Effect of Rifampicin, Ketoconazole, and Omeprazole on the Pharmacokinetics of Sativex
Study to assess the effect of rifampicin, ketoconazole and omeprazole on the pharmacokinetics of a single dose of Sativex and to evaluate the safety of Sativex when given in combination with these other drugs.
- Conditions
- Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4, Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4, Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19 Inhibitor
- Trial name
- NCT01323465
- Testing
- Sativex and rifampicin, Sativex and ketoconazole, Sativex and omeprazole
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jazz Pharmaceuticals
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