Clinical trials: Mental
Schizophrenia
Study of SPG302 in Adults With Schizophrenia
This Phase 2 study described herein will evaluate the safety, efficacy, tolerability, and pharmacodynamics of SPG302 in adults with a primary diagnosis of schizophrenia.
- Trial name
- NCT06442462
- Testing
- SPG302
- Where
- 3 sites in United States, Australia
- Volunteers
- 32 people
- Sponsor
- Spinogenix
Knee Osteoarthritis, Knee Pain Chronic
Gabapentin Regimens and Their Effects on Opioid Consumption
The purpose of this study is to determine the best strategy of administering gabapentin in connection with our current approach to perioperative pain management.
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Opioid Use, Opioid Dependence
- Trial name
- NCT03334903
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Social Anxiety Disorder
Cognitive Behavioral Therapy for Adolescents With Social Anxiety Disorder
The main aim of the present study is to investigate the effectiveness of a disorder specific group cognitive behavior therapy (G-CBT) program for youth SAD, the, Cool Kids Anxiety Program - Social Enhanced (CK-E), developed at…
- Trial name
- NCT03986827
- Testing
- Cool Kids Anxiety Program - Social Enhanced, Cool Kids Anxiety Program
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- University of Aarhus
Mental Health Issue
Effects of Mindfulness Based Elder Care (MBEC) on Psychological and Spiritual Well Being
This study aims to verify the effectiveness of the mindfulness-based elder care (MBEC) therapy developed by McBee (2008) in improving the psychological and spiritual well-being of seniors with disabilities living in residential…
- Trial name
- NCT05123261
- Testing
- the mindfulness-based elder care (MBEC) therapy
- Where
- Taiwan
- Volunteers
- 77 people
- Sponsor
- Mackay Medical College
Sleep Initiation and Maintenance Disorders
A Comparison of the Therapeutic Effect Between Head-point Acupuncture and Conventional Body Acupuncture on Insomnia
The investigators will conduct a single-center, and randomized controlled cases study. A total of 120 participants with insomnia will be enrolled.
- Trial name
- NCT04405427
- Testing
- head acupoints acupuncture, body acupoints acupuncture
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Post-traumatic Stress Disorder (PTSD) Among Road Traffic Injury Victims
Impact of Capacity Building of Healthcare Workers on Management of Post-Traumatic Stress Disorder
This is a community- and hospital-based interventional study consisting of two interventions: Capacity building of healthcare workers (HCWs) in the intervention group (Buea Regional Hospital, selected by simple random…
- Trial name
- NCT07110727
- Testing
- Two days, role play, adult interactive capacity building sessions of healthcare workers on PTSD screening and management. Pre/posttest and change in practice in screening will be used for evaluation
- Where
- 3 sites in Cameroon
- Volunteers
- 70 people
- Sponsor
- University of Buea
Mental Illness
Homelessness Prevention: Psychiatric Care With Representative Payeeship
Money management is a neglected issue in maintaining persons with mental illness in the community. This randomized controlled trial (RCT) assessed whether a community-based representative payee program, i.e., money management of…
- Trial name
- NCT00057161
- Testing
- Coordinated Representative Payeeship with Case Management
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Psychiatric Disorder, Psychiatric Hospitalization
Advanced Chronic Liver Disease Screening by Transient Elstography in Patients Hospitalised in a Psychiatric Unit
Scares data exists concerning the prevalence of chronic liver diseases in people with psychiatric disorders. There are still many barriers to screening and linkage to care for patients having somatic illness.
- Conditions
- Psychiatric Disorder, Psychiatric Hospitalization, Advanced Chronic Liver Disease, Liver Fibrosis
- Trial name
- HEPSY (NCT05602870)
- Testing
- non invasive evaluation of liver fibrosis by transient elastography (Fibroscan ®)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Montpellier
Alcohol Use Disorder (AUD)
Alpha Down Electroencephalography (EEG) Neurofeedback for Alcohol Use Disorder: Feasibility Trial
This pilot study is testing a short brain training program called neurofeedback in adults with alcohol use disorder. Participants will complete three sessions over about one week.
- Trial name
- Neurofeedback (NCT07746154)
- Testing
- EEG Neurofeedback
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Insomnia
Implementation of Internet-based Cognitive Behaviour Therapy for Adolescents With Co-morbid Insomnia
Insomnia is a commonly reported comorbidity for adolescents with psychiatric conditions. It is well-known that insomnia can exacerbate the concurrent psychiatric symptom load.
- Trial name
- NCT03492905
- Testing
- Internet-based Cognitive Behaviour Therapy (iCBT)
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Uppsala University Hospital
Anxiety, Agitated Depression
The Effects of Music Listening on Anxiety and Agitation in People With Mild and Moderate Cognitive Impairment
Advancing age is associated with an increased risk of developing dementia which can lead to a rapid acceleration in both the healthcare costs and caregiver burden.
- Trial name
- NCT05858541
- Testing
- Music Listening, Listening to Audiobooks
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Southern California
Schizophrenia
Examining Risk Factors for Atypical Antipsychotic Metabolic Side Effects
This study will examine possible causes of metabolic side effects in people taking atypical antipsychotic (AAP) medications.
- Trial name
- NCT00815854
- Testing
- Folic Acid
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Michigan
Tinnitus, Sleep Disturbances
Low-intensity TUS for Sleep Disturbances in Patients With Chronic Tinnitus
Background: Tinnitus, as a common symptom, can jeopardize the sleep quality and brain function and even lead to hearing loss and cognitive decline in elderly patients.
- Conditions
- Tinnitus, Sleep Disturbances, Cognition
- Trial name
- NCT06776705
- Testing
- Low-intensity transcranial ultrasound stimulation
- Where
- 2 sites in Hong Kong
- Volunteers
- 14 people
- Sponsor
- Chinese University of Hong Kong
Preschool Age Children, Preschool Education
The Building Resilience Program: Examining Self-Regulation, Behavior, and Resilience in Under-Resourced Preschoolers With ACEs
# Brief Summary The goal of this clinical trial is to learn if a occupational therapy-led trauma-informed care intervention can improve resilience, self-regulation, coping skills, and emotional health in preschoolers ages 2-4…
- Conditions
- Preschool Age Children, Preschool Education, Adverse Childhood Experience, Mental Health
- Trial name
- NCT07170605
- Testing
- Mental health, positive coping strategies promoting self-regulation and adaptive skills, Standard care/School Readiness Condition
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cleveland State University
Stress Disorders, Post-Traumatic
Evaluation of PTSD Family Coach, a Mobile Phone App for Family Members of Individuals With PTSD
The proposed pilot study is designed to test the feasibility, acceptability, and potential effectiveness of a mobile phone application (app) developed by the VA National Center for PTSD (VA NCPTSD) for use by family members of…
- Trial name
- NCT02486705
- Testing
- PTSD Family Coach Full, PTSD Family Coach Basic
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Mental Health
Alternative Care to the Accompaniment Called "Place of Respite" in the Resolution of the Psychotic Crises of Homeless People With Severe Mental Pathology
Document the effectiveness of the "Respite Site" program in relation to the current health system. Document in particular the number and type of constraints, lengths of hospitalization and mode of exit, as well as the exit…
- Trial name
- NCT03992105
- Testing
- prospective cohort
- Volunteers
- 200 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Total Hip Replacement, Pericapsular Nerve Group Bloc
Effect of Pericapsular Nerve Group Block on Postoperative Cognitive Function
The aim of this study was to examine the effect of pericapsular nerve group (PENG) block, which is frequently applied for postoperative analgesia in total hip replacement surgeries performed under spinal anesthesia, on…
- Conditions
- Total Hip Replacement, Pericapsular Nerve Group Bloc, Postoperative Cognitive Dysfunction
- Trial name
- NCT06736405
- Testing
- Pericapsular nerve group block, No Pericapsular nerve group block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Mental Illness
Perceptions and Experiences of (Family Members of) People With Mental Illness About the Chance for Mental Illness in (Future) Children, and Needs for Care and Research
Despite consistent evidence that mental illness runs in families, intergenerational transmission of risk of mental illness is rarely considered in clinical practice.
- Trial name
- PANDAcc (NCT06307366)
- Testing
- No intervention will be used
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Perinatal Loss, Grief
Digital Perinatal Bereavement Support Program for Women After Pregnancy Loss
This study aims to evaluate the effectiveness of a digital perinatal bereavement support program designed for women who have experienced pregnancy loss.
- Conditions
- Perinatal Loss, Grief, Depression Anxiety Disorder
- Trial name
- DPBSP (NCT07545551)
- Testing
- Supportive Care
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Gazi University
Eating Disorders
Targeting Transdiagnostic Self-regulatory Factors and Eating Disorder Pathology Among Adults With BInge-spectrum Eating disOrders: A mHEALTH Interoceptive Exposure Intervention (the Bio-HEALTH Study)
The present study will be fully remote (virtual) and include observational design features (assessments) plus a clinical trial. All assessments will be completed using HIPAA-approved platforms (e.g., Qualtrics, MindLogger EMA…
- Trial name
- NCT06631729
- Testing
- HRV-bio, ED-JITAI
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Minnesota
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