Clinical trials: Mental Disorder
Tobacco Dependence
Tobacco Intervention in Buprenorphine Treatment
Drug addiction treatment patients, including those in treatment for opioid dependence, have a high rate of tobacco dependence, especially cigarette smoking.
- Trial name
- IBIS (NCT01350011)
- Testing
- Innovative System, Standard Treatment Control (STC)
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Mild Cognitive Impairment, Alzheimer Disease
Skeletal Muscle as a Mediator of Exercise Induced Effects on Metabolism & Cognitive Function: Role for Myokines & miRNAs
The purpose of this study is to determine specific changes in muscle secretory profile (myokines, miRNA) in association with neurodegenerative disease progression and metabolic dysfunction.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Parkinson Disease, Healthy Volunteers
- Trial name
- Brain-Muscle (NCT02253732)
- Testing
- 3 months exercise intervention program
- Where
- 2 sites in Slovakia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Slovak Academy of Sciences
Sports Physical Therapy, Multi-Tasking Behavior
A New Dual Task Test Method for Football Players
Multitasking (Dual Task) is a measurement method to evaluate cognitive ability to execute multiple functions at the same time. To perform this test, while participant/patient performing a main skill (for example, walking), a…
- Conditions
- Sports Physical Therapy, Multi-Tasking Behavior, ACL Injury, Kinesiophobia
- Trial name
- NCT05218993
- Testing
- A new dual-task measurement method with images, A new dual-task measurement method with cards
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Menopause, Sleep Quality
Effect of Menopausal Hormone Therapy on Sleep
The Effect of Menopausal Hormone Therapy on Sleep (menoSLEEP) study is investigating the effects of menopausal hormone therapy (MHT) on sleep problems in peri- and postmenopausal women with an indication for MHT.
- Conditions
- Menopause, Sleep Quality, Psychological Wellbeing
- Trial name
- menoSLEEP (NCT07674316)
- Testing
- HRT
- Where
- Switzerland
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Bulimia Nervosa, Binge Eating Behaviour
Wise Eating: A Guided Digital DBT-Based Intervention for Binge Eating
Bulimia Nervosa (BN), characterized by binge eating and purging behaviors, constitutes a chronic psychiatric disorder predominantly affecting young females, characterized by high prevalence and relapse rates.
- Conditions
- Bulimia Nervosa, Binge Eating Behaviour, Anorexia Nervosa, Eating Disorders
- Trial name
- NCT07143214
- Testing
- online dialectical behavior therapy, Waitlist and psychoeducation
- Where
- China
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
ADHD, Attention Deficit Hyperactivity Disorder
Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD
The purpose of the study is to examine the developmental trajectory of response control in boys and girls with ADHD entering adolescence.
- Trial name
- NCT05927506
- Testing
- Other
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Cognitive Impairment, Variable
The Effect of Cognitive Rehabilitation on Cognitive Skills, Academic Performance And Quality of Life in Refugee Children
Children are the most vulnerable group to be affected by war. The long-term effects of exposure to conflict on children's mental, physical and cognitive development have been documented in the context of war and refugee camps.
- Trial name
- NCT05093738
- Testing
- Cognitive Rehabilitation
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Bipolar Disorder, Subsyndromal Depressive Phase
Heart Rate Variability of Patients With Bipolar Disorder in Subsyndromal Depressive Phase
The purposes of this study were: (1) to compare heart rate variability between bipolar patients in subsyndromal depressive phase and healthy controls (2) to evaluate the relation between the severity of subsyndromal depressive…
- Conditions
- Bipolar Disorder, Subsyndromal Depressive Phase, Heart Rate Variability
- Trial name
- NCT01455038
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Anxiety, Depression
CALM for Pregnant and Post-Partum Women
Anxiety and depression is common along pregnant mothers and has been found to increase risk for negative outcomes in both mothers and infants.
- Conditions
- Anxiety, Depression, Depression, Postpartum, Pregnancy Related
- Trial name
- NCT03351465
- Testing
- Coordinated Anxiety Learning and Management
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Prevention, Digital Health
Digital Detox Study
The Digital Detox study is designed as a randomized controlled trial (two unblinded parallel groups) to examine the effects of reducing smartphone screentime on mental health.
- Conditions
- Prevention, Digital Health, Smartphone Addiction
- Trial name
- RESET (NCT06910371)
- Testing
- smartphone screen time reduction
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danube University Krems
Alzheimer Disease, Healthy Aging
Telerehabilitation Alzheimer's Disease Usability (TADU)
Usability evaluation of BrightGo cognitive telerehabilitation system. An experimental system was developed to enhance standard of care (medication effect) for Early Alzheimer's Disease populations.
- Trial name
- TADU (NCT04731311)
- Testing
- Usability evaluation of BrightGo computerized device for cognitive therapy of individuals with early Alzheimer's Disease
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Bright Cloud International Corp
Dementia, Frontotemporal
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VES001 in Healthy Participants
This is a Phase 1, randomized, placebo-controlled, double-blind study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single and multiple doses of VES001 in a two part followed by a…
- Trial name
- SORT-IN-1 (NCT06226064)
- Testing
- VES001
- Where
- Netherlands
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Vesper Biotechnologies ApS
Substance Abuse, Opioid Dependence
Methadone Oxytocin Option
The purpose of the study is to examine the effects of intranasal oxytocin administration on social cognition in patients receiving methadone maintenance treatment (MMT), examine the effects of intranasal oxytocin administration…
- Conditions
- Substance Abuse, Opioid Dependence, Methadone Treatment
- Trial name
- MOO (NCT01728909)
- Testing
- Oxytocin, Saline Nasal Spray
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke, Caregiving Burden
CaknaStrok Education Package for Stroke Caregivers
This study evaluated the feasibility and potential effectiveness of the CaknaStrok Education Package (CEP), a culturally tailored education package developed to support informal caregivers of stroke survivors.
- Conditions
- Stroke, Caregiving Burden, Caregiver, Caregiver Burden for Those Who Care for Adults With Impaired Functional Status
- Trial name
- CaknaStrok (NCT07807332)
- Testing
- CaknaStrok Education Package (CEP)
- Where
- Malaysia
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Clinical Research Centre, Malaysia
Schizophrenia, Psychotic Disorder NOS
The Effect of N-Acetyl Cysteine on Cortical Erosion in Early Stage Schizophrenia
The primary objective of this study is to determine if NAC, added to existing antipsychotic treatment, is superior to placebo for cortical erosion in patients with early stage psychosis.
- Conditions
- Schizophrenia, Psychotic Disorder NOS, Schizoaffective Disorder, Schizophreniform
- Trial name
- Breier-Stanley (NCT01339858)
- Testing
- N-Acetyl Cysteine, sugar pill
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hand Massage
The Effect of the Hand Massage A Women Undergoing Brachytherapy
Background Gynecologic cancers are among the ten most common cancers among women. During brachytherapy, women can have pain and situational anxiety due to the treatment.
- Trial name
- NCT05937607
- Testing
- Hand massage
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Death Anxiety, Occupational Stress
Effect of Expressive Arts Therapy on Death Anxiety in Intensive Care Unit Nurses
This randomized controlled trial aimed to evaluate the effect of expressive arts therapy on death anxiety among intensive care unit nurses.
- Conditions
- Death Anxiety, Occupational Stress, Psychological Distress
- Trial name
- Expressive Art (NCT07462936)
- Testing
- Expressive Arts Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Alzheimer Disease
Blood Biomarker of Alzheimer's Disease (AD)
Currently, no cures or disease modifying therapies exist for Alzheimer's disease (AD). This is partially due to the inability to detect the disease before it has progressed to a stage where there are clinical manifestations.
- Trial name
- NCT03340571
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Duke University
Overweight and Obesity, Health Behavior
Location-based Smartphone Technology to Guide College Students Healthy Choices Ph II
College students are in a newly independent phase of life; many of whom encounter unhealthy dietary decision- making, barriers to physical activity, and poor sleep behaviors.
- Conditions
- Overweight and Obesity, Health Behavior, Sleep Deprivation
- Trial name
- NCT02996864
- Testing
- Healthy Detours App, Fat Secret App
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
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