Clinical trials: Mental Distress, active
HIV, HIV - Human Immunodeficiency Virus
Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women
Purpose of this Study: The main purpose of this study is to adapt an existing evidence-based intervention, Project Accept Post-Test Support Services (PTSS) Module 3, specifically for pregnant and postpartum women living with HIV…
- Conditions
- HIV, HIV - Human Immunodeficiency Virus, Postpartum, Pregnancy
- Trial name
- WAT (NCT07064928)
- Testing
- Adapted Project Accept's Post-Test Support Services (PTSS) Module 3
- Where
- Ghana
- Volunteers
- 163 people
- Sponsor
- University of California, San Francisco
Psychological Distress, Stress Psychological
A Community-based, Peer-led Counseling Service: A Hybrid Type 3 Effectiveness-implementation Study
The goal of this observational study is to learn how a community-based peer counselling service works in everyday practice and whether it helps people who are going through a psychologically difficult time.
- Conditions
- Psychological Distress, Stress Psychological, Mental Health, Recovery
- Trial name
- NCT07879443
- Volunteers
- 65 people
- Sponsor
- St.Gallen University of Applied Sciences
Type 2 Diabetes, Mental Health
Technology-Enabled Collaborative Care for Diabetes and Mental Health
Managing both type 2 diabetes and mental health challenges can be difficult, and many people do not receive care that supports both.
- Conditions
- Type 2 Diabetes, Mental Health, Diabetes Distress
- Trial name
- TECC-DM (NCT07181863)
- Testing
- Health coaching, Educational emails
- Where
- 2 sites in Canada
- Volunteers
- 160 people
- Sponsor
- McMaster University
Mental Health, Parenting / Maternal Behavior
Healing Hearts: A Mindfulness App for Parents Navigating Divorce or Separation
This study examines online programs for parents navigating divorce or separation. Researchers will study whether a self-guided mindfulness app called Healing Hearts, followed by a self-guided online parenting program called the…
- Conditions
- Mental Health, Parenting / Maternal Behavior, Parenting Anxiety, Parenting Behavior
- Trial name
- NCT07871916
- Testing
- Healing Hearts, electronic New Beginnings Program, Curated internet resources
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Relationship Distress, Mental Health
Relationship Checkups to Reduce Veteran Suicide Risk
This study compares two approaches to working with Veterans that have a mix of mental health and relationship concerns in primary care. One approach is a 3-session couple-based program called the Brief Relationship Checkup (BRC).
- Trial name
- BRC RCT (NCT05525676)
- Testing
- Brief Relationship Checkup (BRC), Co-Located Collaborative Care (CCC)
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- VA Office of Research and Development
Altered Mental Status, Sepsis
Pre-hospital Ventilation Clinical Study
This study will collect and characterize ventilator use during patient care with a ZOLL 731 Series ventilator in a pre-hospital setting.
- Conditions
- Altered Mental Status, Sepsis, Heart Failure, Hemorrhage
- Trial name
- NCT05604430
- Testing
- 731 Series Ventilator
- Where
- 5 sites in United States
- Volunteers
- 500 people
- Sponsor
- Zoll Medical Corporation
Youth Mental Health, Psychological Distress in Adolescents and Young Adults
VIPeerAgent for Adolescent Mental Health
This three-arm parallel randomized controlled trial aims to evaluate the effectiveness of VIPeerAgent, a virtual peer support agent, in improving mental health outcomes among adolescents and young adults aged 14-25 years…
- Conditions
- Youth Mental Health, Psychological Distress in Adolescents and Young Adults, Early Intervention
- Trial name
- NCT07778758
- Testing
- Virtual Peer Agent Intervention, Human peer mentor
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Sun Yat-sen University
Mental Health, HIV
"Gwan Enjoy Life:" A Peer-Supported Mental Health Mentoring Intervention to Improve Engagement in Care Among Sexual Minority Men Living With HIV in Jamaica
Sexual minority men (SMM) in Jamaica face many challenges that affect their health and well-being. Although they make up a relatively small part of the population, they are much more likely to be living with HIV than the general…
- Conditions
- Mental Health, HIV, Pyschological Distress, Suicidal Ideation
- Trial name
- GwanEnjoyLife (NCT07762612)
- Testing
- Gwan Enjoy Life Interveniton
- Where
- Jamaica
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pelvic Floor Disorder, Loneliness
Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial
The goal of this clinical trial is to learn whether a postpartum chatbot powered by generative artificial intelligence (genAI) can help new mothers get better pelvic floor health information and feel less lonely after childbirth.
- Conditions
- Pelvic Floor Disorder, Loneliness, Postpartum, Mental Health
- Trial name
- PEARL (NCT07223736)
- Testing
- Generative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of California, San Diego
Mental Distress, Insomnia
Cognitive Behavioural Therapy for Insomnia Among Young People With Moderate Level of Mental Distress in Hong Kong
This randomized controlled trial (RCT) aims to evaluate the effectiveness of a Cognitive Behavioral Therapy for Insomnia (CBTi) intervention in enhancing sleep quality, overall quality of life, functional ability, and reducing…
- Trial name
- NCT07230899
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Volunteers
- 160 people
- Sponsor
- The University of Hong Kong
HIV, Drug Use
Development of a Multilevel HIV Prevention Intervention for the Emergency Department
The goal of this clinical trial is to pilot test a psychosocial-behavioral mobile health (mHealth) human immunodeficiency virus (HIV) prevention intervention in people who use drugs presenting to the emergency department (ED).
- Conditions
- HIV, Drug Use, Mental Health, Psychological Distress
- Trial name
- mSYNC (NCT06331767)
- Testing
- mSYNC
- Volunteers
- 100 people
- Sponsor
- Brigham and Women's Hospital
Caregiver Stress, Caregiver Stress Syndrome
ACT Group for Family Caregivers of Stroke Survivors
The goal of this study is to evaluate the efficacy of group-based ACT intervention in improving the levels of psychological distress in caregivers of stroke survivors. The main questions it aims to answer are: 1.
- Conditions
- Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress
- Trial name
- NCT07528261
- Testing
- Group-based ACT Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Wright Institute
Psychological Distress, PTSD
Boosting Refugee Integration Through Psychological Intervention
Refugees and asylum seekers (RAS) face numerous stressors and adversities which put them at risk for developing mental health problems. However, access to adequate mental health care in host countries is limited.
- Conditions
- Psychological Distress, PTSD, Trauma, Common Mental Health Problems
- Trial name
- BRIGHT (NCT06776523)
- Testing
- Problem Management Plus
- Where
- Switzerland
- Volunteers
- 1,200 people
- Sponsor
- University of Zurich
Mental Health Disorder, Depression
Digital Lifestyle Intervention for Mental Health Among Migrants: Randomized Controlled Trial
Migrant populations experience elevated levels of psychological distress while facing barriers to accessing mental health care. Lifestyle factors such as physical activity, sleep, diet, and social engagement are closely linked to…
- Conditions
- Mental Health Disorder, Depression, Anxiety, Psychological Distress
- Trial name
- LIFT-RCT (NCT07545239)
- Testing
- Digital Lifestyle Intervention
- Volunteers
- 240 people
- Sponsor
- Karolinska Institutet
Palliative Care, Refractory Pain
Single Arm, Monocentric, Pilot Feasibility Study on an Interactive Virtual Reality Program in 20 Complex In-clinic Palliative Care Patients
Palliative care patients frequently face a "symptom cluster" of pain (up to 96%), fatigue (up to 90%), and anxiety (up to 79%), which severely degrades their quality of life in their final months.The study is built on the concept…
- Conditions
- Palliative Care, Refractory Pain, Anxiety, Depression Disorders
- Trial name
- ZENCTUARY_VR+ (NCT07545928)
- Testing
- ZenctuaryVR+ Interactive Virtual Reality
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Mental Distress
Narrative Therapy Among Young People With Moderate Level of Mental Distress in Hong Kong
This cluster randomized controlled trial (cRCT) aims to evaluate the effectiveness of a narrative therapy (NT) intervention in (i) reducing mental distress, depressive symptoms, and anxiety, as well as (ii) enhancing perceived…
- Trial name
- NCT07231406
- Testing
- Narrative Therapy
- Where
- Hong Kong
- Volunteers
- 770 people
- Sponsor
- The University of Hong Kong
Mental Health Issue, Depression
Development and Validation of Psycho-Social Program (PSP)
The study aims to determine the effectiveness of a structured psycho-social program (PSP) in improving mental health outcomes among patients with Type 2 diabetes mellitus (T2DM).
- Conditions
- Mental Health Issue, Depression, Diabetes Distress, Quality of Life
- Trial name
- PSP-T2DM (NCT07456410)
- Testing
- Psycho-Social Program
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Government College University Faisalabad
Mental Health, Psychological Distress
Peer Counselling to Reduce Psychological Distress and Exposure to Violence Among Sexual and Gender Minorities
Lesbian, Gay, Bisexual, Transgender, Intersex, Queer, Asexual, and other sexually or gender diverse (LGBTIQA+) communities in many countries face high levels of mental health problems compared to the general population.
- Conditions
- Mental Health, Psychological Distress, Secondary Violence Reduction, Discrimination
- Trial name
- SAATHI (NCT06979193)
- Testing
- SAATHI intervention (Augmented PM+ counseling), SAATHI intervention with Peer-Led Group Meetings
- Where
- 6 sites in Nepal
- Volunteers
- 960 people
- Sponsor
- Public Health and Environment Research Centre (PERC), Nepal
Mental Health, Psychological Distress
Self-Help Plus to Enhance Early Development: A Cluster-Randomized Controlled Trial of Maternal Mental Health, Child Cognitive Abilities, and Socio-Behavioral Skills Among Refugee Mothers and Their Preschool-Aged Children in Rhino Camp, Uganda
This study evaluates whether the group-based mental health program Self-Help Plus (SH+) can improve the mental health, wellbeing, and functioning of refugee mothers and their preschool-aged children living in Rhino Refugee…
- Conditions
- Mental Health, Psychological Distress, Child Wellbeing, Child Mental Health
- Trial name
- SEED (NCT07062341)
- Testing
- Self-Help Plus (SH+), Enhanced Usual Care (EUC)
- Where
- Uganda
- Volunteers
- 725 people
- Sponsor
- Uppsala University
Depression - Major Depressive Disorder, Mental Distress
The Effect of Digital Markers in the Self-management of Depressive Symptoms
The purpose of the MENTINA trial is to investigate the effect of using the smartphone-based MENTINA app for self-monitoring of depressive symptoms and rule-based feedback in individuals with current or previous depression…
- Trial name
- MENTINA (NCT06919133)
- Testing
- The MENTINA app, Control
- Where
- 3 sites in Denmark, Germany and 1 more
- Volunteers
- 660 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital