Clinical trials: Mental Function
Depression
Working Memory Training for Dysphoric Students
Depression is associated with impairments in executive functions, including working memory (WM) which is needed to maintain and manipulate goal-relevant information.
- Trial name
- NCT02184481
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Relative Energy Deficiency in Sport
Using Energy Availability as a Strategy to Explore the Effects of Relative Energy Deficiency in Sport on Athletes
The goal of this type of study:clinical trial is to test, compare etc. In describe participant population health conditions. Participants will diet record,maintain training and life.
- Trial name
- NCT05649267
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Chen Ming You
Obesity (BMI>30), Postoperative Cognitive Function
Postoperative Cognitive Function After Different Anesthetic Techniques in Obese Patients
Obese patients are at increased risk of postoperative cognitive dysfunction (POCD). The effects of different anesthetic techniques on postoperative cognitive function remain controversial.
- Trial name
- NCT07665645
- Testing
- Sevoflurane (Volatile Anesthetic), propofol, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Self, Self-Perception
Immersive Training on Metacognitive Capacities of Young People
Metacognitive abilities and self-knowledge are necessary for psychological maturation and good mental functioning of individuals.
- Conditions
- Self, Self-Perception, Self Esteem
- Trial name
- VRtraining (NCT05899257)
- Testing
- Immersive Training using EYME
- Where
- Spain
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Delayed Sleep Phase Syndrome
Are Patients Suffering From DSPS Show Compromising in Everyday Functions and Abilities Before Handling the Disorder?
The purpose of this study is to determine whether the known treatment for DSPS also improve the cognitive ability and mood of the patients.
- Trial name
- NCT02962037
- Testing
- Melatonin and light therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lilach Kemer
Depression, Anxiety, PTSD
A Scalable Model for Promoting Functioning and Well-Being Among Veterans With a History of Mental Health Challenges Via Meaningful Social Interactions: Project V-SPEAK!
The goal of this study is to refine and test a strategy for engaging veterans with symptoms of depression and/or anxiety as volunteers to help English language learners (ELLs) improve their speaking skills via structured…
- Trial name
- V-SPEAK! (NCT05506839)
- Testing
- Intervention (videoconferencing)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bipolar Depression
Functional Connectivity in Mood Regulating Circuit In Bipolar Depression and Mania
The purpose of this study is to find out what parts of the brain have increased or decreased activity with individuals who have bipolar disorder and how medicine changes this activity in bipolar subjects.
- Trial name
- NCT00457054
- Testing
- Lithium
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Indiana University
Postpartum Depression, Mood Disorders
Whole-Body Hyperthermia for Mood and Anxiety Disorders
This study aims to examine the scientific mechanisms of whole-body hyperthermia (WBH), a novel, rapidly acting, single session antidepressant and anxiolytic therapy.
- Conditions
- Postpartum Depression, Mood Disorders, Anxiety Disorders, Postpartum Anxiety
- Trial name
- NCT06144294
- Testing
- Whole-Body Hyperthermia, fMRI
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Memory Impairment, Sleep Disorder
Improving Patient Memory for Treatment for Mild Cognitive Impairment
The main empirical question to be addressed is: What types of memory support are most potent for patients who are experiencing a mild cognitive impairment (MCI) relative to non-MCI patients?
- Trial name
- NCT05668481
- Testing
- Transdiagnostic sleep and circadian intervention (TranS-C)
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Aging, Nursing Homes
Effect of Sunlight Exposure and Outdoor Activities on Depression, Cognition and Quality of Life in the Elderly
Background: The transition to long-term care facility can be a stressful and emotional event for the elderly. The evidences showed that the prevalence of depression and the cognition impairment were higher in the…
- Conditions
- Aging, Nursing Homes, Depression in Old Age, Cognitive Impairment
- Trial name
- NCT03304301
- Testing
- sunlight exposure
- Where
- Taiwan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Chiayi Christian Hospital
Schizophrenia, Renal Impairment
A Study of the Pharmacokinetics of ER OROS Paliperidone in Volunteers With Normal or Impaired Renal Function
The purpose of this study is to evaluate the pharmacokinetics of a single oral dose of 3 mg extended release paliperidone (ER OROSÃ' paliperidone) in patients with varying degrees of renal impairment (mild, moderate, and severe)…
- Trial name
- NCT00791401
- Testing
- ER OROS Paliperidone
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Anorexia Nervosa
Lung Function Tests in Adolescents With Anorexia Nervosa
The investigators hypothesize that lung function would be adversely affected at the hypocaloric stage of adolescents suffering from anorexia nervosa.
- Trial name
- NCT00942929
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
Mild Cognitive Impairment (MCI), Cognition
LpD3.5 Intervention Study in Older Adults- LISA-I Trial
This randomized placebo-controlled clinical study, called the LpD3.5 Intervention Study in Older Adults (LISA), aims to evaluate whether a heat-inactivated postbiotic of human origin (LpD3.5) can serve as a non-pharmacological…
- Conditions
- Mild Cognitive Impairment (MCI), Cognition, Brain Aging, Microbiome Dysbiosis
- Trial name
- Postbiotics (NCT07794956)
- Testing
- LpD3.5
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Aging and Exercise Impacts on Glymphatic Function
Aging and Exercise Impacts on Glymphatic Function
This is a prospective, interventional, non-blinded, single center research project that will recruit cognitively unimpaired subjects in the 25-55 year old and 55-75 year old range.
- Trial name
- NCT07775196
- Testing
- Acute Aerobic exercise
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Major Depressive Disorder
Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response.
In this project we aim to further refine indications for the use of the thyroid hormone - T3 for patients suffering from depression.
- Trial name
- NCT00421369
- Testing
- sertraline, triiodothyronine (T3), reboxetine
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dyspepsia, Anxiety
SSRI Study for Functional Dyspepsia (SS)
Background: Functional dyspepsia is one of the commonest digestive disorders. The pathophysiology of functional dyspepsia (FD) is uncertain.
- Conditions
- Dyspepsia, Anxiety, Depression
- Trial name
- NCT02153567
- Testing
- Escitalopram
- Where
- Hong Kong
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Post-traumatic Stress Disorder (PTSD), Trauma
Functional Brain Imaging in PTSD
Patients with post-traumatic stress disorder (PTSD) have abnormalities in the function of the amygdala and medial prefrontal cortex (particularly anterior cingulate), in addition to abnormalities of hippocampal volume.
- Trial name
- NCT02053532
- Testing
- Positron emission tomography/magnetic resonance imaging
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cognitive Impairment, Executive Dysfunction
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
Complaints about memory and thinking are common in women as they go through menopause and estrogen levels fall. The ovarian hormone estrogen is important for supporting normal cognitive function, and changes in brain activity and…
- Conditions
- Cognitive Impairment, Executive Dysfunction, Endothelial Dysfunction, Cardiovascular Disease
- Trial name
- NCT02122198
- Testing
- Leuprolide acetate, Estradiol, Medroxyprogesterone
- Where
- 2 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sleep Deprivation
The Neurocognitive Effects of Total and Partial Sleep Deprivation in Younger Adults.
This study aims to examine how total and partial sleep deprivation affect brain function, cognitive performance, and biomarkers related to stress and inflammation in the same participants using a crossover design.
- Trial name
- NCT07822009
- Testing
- Total sleep deprivation, Partial sleep deprivation, Normal sleep
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
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